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  1. Article ; Online: Network pharmacology analysis of

    Nandi, Arijit / Nigar, Tanzeem / Das, Anwesha / Dey, Yadu Nandan

    Journal of biomolecular structure & dynamics

    2023  , Page(s) 1–15

    Abstract: ... Plumbago ... ...

    Abstract Plumbago zeylanica
    Language English
    Publishing date 2023-11-10
    Publishing country England
    Document type Journal Article
    ZDB-ID 49157-3
    ISSN 1538-0254 ; 0739-1102
    ISSN (online) 1538-0254
    ISSN 0739-1102
    DOI 10.1080/07391102.2023.2280681
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2093: Show issues Location:
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    ab Jg. 2022: Lesesaal (EG)

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  2. Article: The Abundant Phytocannabinoids in Rheumatoid Arthritis: Therapeutic Targets and Molecular Processes Identified Using Integrated Bioinformatics and Network Pharmacology.

    Nandi, Arijit / Das, Anwesha / Dey, Yadu Nandan / Roy, Kuldeep K

    Life (Basel, Switzerland)

    2023  Volume 13, Issue 3

    Abstract: The endocannabinoid system consists of several phytocannabinoids, cannabinoid receptors, and enzymes that aid in numerous steps necessary to manifest any pharmacological activity. It is well known that the endocannabinoid system inhibits the pathogenesis ...

    Abstract The endocannabinoid system consists of several phytocannabinoids, cannabinoid receptors, and enzymes that aid in numerous steps necessary to manifest any pharmacological activity. It is well known that the endocannabinoid system inhibits the pathogenesis of the inflammatory and autoimmune disease rheumatoid arthritis (RA). To the best of our knowledge, no research has been done that explains the network-pharmacology-based anti-rheumatic processes by focusing on the endocannabinoid system. Therefore, the purpose of this study is to further our understanding of the signaling pathways, associated proteins, and genes underlying RA based on the abundant natural endocannabinoids. The knowledge on how the phytocannabinoids in
    Language English
    Publishing date 2023-03-05
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662250-6
    ISSN 2075-1729
    ISSN 2075-1729
    DOI 10.3390/life13030700
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Inhibitory activity of

    Chattaraj, Bornika / Nandi, Arijit / Das, Anwesha / Sharma, Amit / Dey, Yadu Nandan / Kumar, Dharmendra / R, Mogana

    Frontiers in pharmacology

    2023  Volume 13, Page(s) 982419

    Abstract: The decoction of the whole plant ... ...

    Abstract The decoction of the whole plant of
    Language English
    Publishing date 2023-01-20
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587355-6
    ISSN 1663-9812
    ISSN 1663-9812
    DOI 10.3389/fphar.2022.982419
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Transcriptional Regulation of the Hippo Pathway: Current Understanding and Insights from Single-Cell Technologies.

    Paul, Sayantanee / Xie, Shiqi / Yao, Xiaosai / Dey, Anwesha

    Cells

    2022  Volume 11, Issue 14

    Abstract: The Hippo pathway regulates tissue homeostasis in normal development and drives oncogenic processes. In this review, we extensively discuss how YAP/TAZ/TEAD cooperate with other master transcription factors and epigenetic cofactors to orchestrate a broad ...

    Abstract The Hippo pathway regulates tissue homeostasis in normal development and drives oncogenic processes. In this review, we extensively discuss how YAP/TAZ/TEAD cooperate with other master transcription factors and epigenetic cofactors to orchestrate a broad spectrum of transcriptional responses. Even though these responses are often context- and lineage-specific, we do not have a good understanding of how such precise and specific transcriptional control is achieved-whether they are driven by differences in TEAD paralogs, or recruitment of cofactors to tissue-specific enhancers. We believe that emerging single-cell technologies would enable a granular understanding of how the Hippo pathway influences cell fate and drives oncogenic processes, ultimately allowing us to design better pharmacological agents against TEADs and identify robust pharmacodynamics markers of Hippo pathway inhibition.
    MeSH term(s) Carcinogenesis ; Gene Expression Regulation ; Hippo Signaling Pathway/genetics ; Humans ; Protein Serine-Threonine Kinases/genetics ; Signal Transduction ; Single-Cell Analysis ; Transcription Factors/metabolism
    Chemical Substances Transcription Factors ; Protein Serine-Threonine Kinases (EC 2.7.11.1)
    Language English
    Publishing date 2022-07-17
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2661518-6
    ISSN 2073-4409 ; 2073-4409
    ISSN (online) 2073-4409
    ISSN 2073-4409
    DOI 10.3390/cells11142225
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: The Abundant Phytocannabinoids in Rheumatoid Arthritis

    Arijit Nandi / Anwesha Das / Yadu Nandan Dey / Kuldeep K. Roy

    Life, Vol 13, Iss 700, p

    Therapeutic Targets and Molecular Processes Identified Using Integrated Bioinformatics and Network Pharmacology

    2023  Volume 700

    Abstract: The endocannabinoid system consists of several phytocannabinoids, cannabinoid receptors, and enzymes that aid in numerous steps necessary to manifest any pharmacological activity. It is well known that the endocannabinoid system inhibits the pathogenesis ...

    Abstract The endocannabinoid system consists of several phytocannabinoids, cannabinoid receptors, and enzymes that aid in numerous steps necessary to manifest any pharmacological activity. It is well known that the endocannabinoid system inhibits the pathogenesis of the inflammatory and autoimmune disease rheumatoid arthritis (RA). To the best of our knowledge, no research has been done that explains the network-pharmacology-based anti-rheumatic processes by focusing on the endocannabinoid system. Therefore, the purpose of this study is to further our understanding of the signaling pathways, associated proteins, and genes underlying RA based on the abundant natural endocannabinoids. The knowledge on how the phytocannabinoids in Cannabis sativa affect the endocannabinoid system was gathered from the literature. SwissTarget prediction and BindingDB databases were used to anticipate the targets for the phytocannabinoids. The genes related to RA were retrieved from the DisGeNET and GeneCards databases. Protein–protein interactions (high confidence > 0.7) were carried out with the aid of the string web server and displayed using Cytoscape. The Kyoto Encyclopedia of Genes and Genomes (KEGG) metabolic pathway analysis was used to perform enrichment analyses on the endocannabinoid–RA common targets. ShinyGO 0.76 was used to predict the biological processes listed in the Gene Ontology (GO) classification system. The binding affinity between the ligand and the receptors was precisely understood using molecular docking, induced-fit docking, and a molecular dynamics simulation. The network pharmacology analyses predicted that processes like response to oxygen-containing compounds and peptodyl-amino acid modification are related to the potential mechanisms of treatment for RA. These biological actions are coordinated by cancer, neuroactive ligand–receptor interaction, lipids and atherosclerosis, the calcium signaling pathway, and the Rap1 signaling pathway. According to the results of molecular docking, in the context of RA, ...
    Keywords cannabis ; Cannabis sativa ; endocannabinoid system ; inflammation ; network pharmacology ; Science ; Q
    Subject code 612
    Language English
    Publishing date 2023-03-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Synthesis, Kinetics, Reaction Mechanism, and Bioactivity Assays of a Dimeric Palladium Complex.

    Dey, Anwesha / Kumar, Ramesh / Dutta, Bhramar / Bandopadhyay, Rajib / Chakrabortty, Sankha / Khan, Moonis Ali / Jeon, Byong Hun / Ghosh, Alak Kumar

    ACS omega

    2023  Volume 8, Issue 48, Page(s) 45653–45667

    Abstract: A dimer of Pd(II), [(bpy)Pd(μ-OH) ...

    Abstract A dimer of Pd(II), [(bpy)Pd(μ-OH)
    Language English
    Publishing date 2023-11-20
    Publishing country United States
    Document type Journal Article
    ISSN 2470-1343
    ISSN (online) 2470-1343
    DOI 10.1021/acsomega.3c05944
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Network pharmacology and molecular modelling study of

    Chattaraj, Bornika / Khanal, Pukar / Nandi, Arijit / Das, Anwesha / Sharma, Amit / Mitra, Soumya / Dey, Yadu Nandan

    Journal of biomolecular structure & dynamics

    2023  Volume 41, Issue 24, Page(s) 15400–15410

    Abstract: In view of the ethno medicinal use ... ...

    Abstract In view of the ethno medicinal use of
    MeSH term(s) Asteraceae ; Network Pharmacology ; Nephrolithiasis/drug therapy ; Nephrolithiasis/genetics ; Extracellular Space ; Molecular Docking Simulation ; Drugs, Chinese Herbal
    Chemical Substances Drugs, Chinese Herbal
    Language English
    Publishing date 2023-03-13
    Publishing country England
    Document type Journal Article
    ZDB-ID 49157-3
    ISSN 1538-0254 ; 0739-1102
    ISSN (online) 1538-0254
    ISSN 0739-1102
    DOI 10.1080/07391102.2023.2189476
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2093: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  8. Article ; Online: Evaluation of management practices in rice-wheat cropping system using multicriteria decision-making methods in conservation agriculture.

    Biswas, Tufleuddin / Majumder, Anurup / Dey, Shamik / Mandal, Anwesha / Ray, Soumik / Kapoor, Promil / Emam, Walid / Kanthal, Sahely / Ishizaka, Alessio / Matuka, Adelajda

    Scientific reports

    2024  Volume 14, Issue 1, Page(s) 8600

    Abstract: In this study, we employed two multiple criteria decision-making (MCDM) methods, namely the Technique for Order Preference by Similarity to Ideal Solution (TOPSIS) and the Analytic Hierarchic Process (AHP), to determine the best management choice for the ...

    Abstract In this study, we employed two multiple criteria decision-making (MCDM) methods, namely the Technique for Order Preference by Similarity to Ideal Solution (TOPSIS) and the Analytic Hierarchic Process (AHP), to determine the best management choice for the cultivation of wheat with a regime of conservation agriculture (CA) practices. By combining alternative tillage approaches, such as reduced tillage and zero tillage, with the quantity of crop residues and fertilizer application, we were able to develop the regime of CA practices. The performance of the regimes compared to the conventional ones was then evaluated using conflicting parameters relating to energy use, economics, agronomy, plant protection, and soil science. TOPSIS assigned a grade to each alternative based on how close it was to the ideal solution and how far away it was from the negative ideal solution. However, employing AHP, we determined the weights of each of the main and sub-parameters used for this study using pairwise comparison. With TOPSIS, we found ZERO1 (0% residue + 100% NPK) followed by ZERO4 (50%residue + 100% NPK), and ZERO2 (100% residue + 50% NPK) were the best performing tillage-based alternatives. To best optimize the performance of wheat crops under various CA regimes, TOPSIS assisted the decision-makers in distinguishing the effects of the parameters on the outcome and identifying the potential for maneuvering the weak links. The outcomes of this investigation could be used to improve management techniques for wheat production with CA practices for upscaling among the farmers.
    MeSH term(s) Humans ; Oryza ; Triticum ; Agriculture ; Crops, Agricultural ; Farmers
    Language English
    Publishing date 2024-04-13
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-024-58022-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Synthesis, Kinetics, Reaction Mechanism, and Bioactivity Assays of a Dimeric Palladium Complex

    Anwesha Dey / Ramesh Kumar / Bhramar Dutta / Rajib Bandopadhyay / Sankha Chakrabortty / Moonis Ali Khan / Byong Hun Jeon / Alak Kumar Ghosh

    ACS Omega, Vol 8, Iss 48, Pp 45653-

    2023  Volume 45667

    Keywords Chemistry ; QD1-999
    Language English
    Publishing date 2023-11-01T00:00:00Z
    Publisher American Chemical Society
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: Establishment of seed biopriming in salt stress mitigation of rice plants by mangrove derived Bacillus sp

    Dutta, Bhramar / Datta, Arunava / Dey, Anwesha / Ghosh, Alak K. / Bandopadhyay, Rajib

    Biocatalysis and Agricultural Biotechnology. 2023 Feb. 07, p.102626-

    2023  , Page(s) 102626–

    Abstract: Salinity stress is one of the growing challenges for agro-ecosystems. Present study aimed to explore the role of halotolerant bacteria in alleviation of salinity stressed rice plants. Bacillus sp. strain PnD was isolated from Indian Sundarban Mangrove ... ...

    Abstract Salinity stress is one of the growing challenges for agro-ecosystems. Present study aimed to explore the role of halotolerant bacteria in alleviation of salinity stressed rice plants. Bacillus sp. strain PnD was isolated from Indian Sundarban Mangrove Forest, conferred plant growth promoting (PGP) traits like indole 3-acetic acid (IAA) production, phosphate solubilization, siderophore production but had negative effect of 1-aminoacyclopropane 1-carboxylate (ACC) deaminase activity. Rice seeds (Oryza sativa L.) of Amal-Mana variety were subjected to salinity stress for 24 hours by being immersing in 1% NaCl. Another set of seeds were soaked in a broth cultured with Bacillus sp strain PnD, containing 1% NaCl in the media, denoted as bioprimed condition. The seeds that were soaked in distilled water had no salt stress and weren't primed, served as control. All the treatments were assigned randomly to the seeds and each treatment was replicated three times resulting in nine experimental units. Completely randomized design was adopted in this experiment. Overall results showed bioprimed seeds soaked in 1% NaCl for 24 hours had significantly increased germination percentage, seedling growth, photosynthetic pigments content etc. compared to control and non-primed salinity exposed plants. Scanning electron micrograph revealed root colonization of bacteria in bioprimed seedlings, tissue distortion was also noted during salt stress. The study revealed that Bacillus sp. strain PnD is a potential plant growth promoting bacterium (PGPB), and the seed biopriming technique efficiently mitigate inhibitory effects of salinity in rice plants.
    Keywords Bacillus (bacteria) ; Oryza sativa ; agricultural biotechnology ; agroecosystems ; bacteria ; biocatalysis ; germination ; indole acetic acid ; mangrove forests ; phosphates ; photosynthesis ; rice ; salinity ; salt stress ; salt tolerance ; seedling growth ; siderophores ; solubilization ; Bacillus sp. ; Biopriming ; PGPB
    Language English
    Dates of publication 2023-0207
    Publishing place Elsevier Ltd
    Document type Article ; Online
    Note Pre-press version
    ZDB-ID 2642052-1
    ISSN 1878-8181
    ISSN 1878-8181
    DOI 10.1016/j.bcab.2023.102626
    Database NAL-Catalogue (AGRICOLA)

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