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  1. Article ; Online: Monitoring non-pharmaceutical public health interventions during the COVID-19 pandemic.

    Shen, Yannan / Powell, Guido / Ganser, Iris / Zheng, Qulu / Grundy, Chris / Okhmatovskaia, Anya / Buckeridge, David L

    Scientific data

    2021  Volume 8, Issue 1, Page(s) 225

    MeSH term(s) COVID-19/prevention & control ; Communicable Disease Control ; Crowdsourcing ; Databases, Factual ; Health Policy ; Humans ; Pandemics/prevention & control
    Language English
    Publishing date 2021-08-24
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2775191-0
    ISSN 2052-4463 ; 2052-4463
    ISSN (online) 2052-4463
    ISSN 2052-4463
    DOI 10.1038/s41597-021-01001-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Effectiveness of mRNA Booster Vaccine Against Coronavirus Disease 2019 Infection and Severe Outcomes Among Persons With and Without Immune Dysfunction: A Retrospective Cohort Study of National Electronic Medical Record Data in the United States.

    Sun, Jing / Zheng, Qulu / Anzalone, Alfred J / Abraham, Alison G / Olex, Amy L / Zhang, Yifan / Mathew, Jomol / Safdar, Nasia / Haendel, Melissa A / Segev, Dorry / Islam, Jessica Y / Singh, Jasvinder A / Mannon, Roslyn B / Chute, Christopher G / Patel, Rena C / Kirk, Gregory D

    Open forum infectious diseases

    2024  Volume 11, Issue 2, Page(s) ofae019

    Abstract: Background: Real-world evidence of coronavirus disease 2019 (COVID-19) messenger RNA (mRNA) booster effectiveness among patients with immune dysfunction are limited.: Methods: We included data from patients in the United States National COVID Cohort ... ...

    Abstract Background: Real-world evidence of coronavirus disease 2019 (COVID-19) messenger RNA (mRNA) booster effectiveness among patients with immune dysfunction are limited.
    Methods: We included data from patients in the United States National COVID Cohort Collaborative (N3C) who completed ≥2 doses of mRNA vaccination between 10 December 2020 and 27 May 2022. Immune dysfunction conditions included human immunodeficiency virus infection, solid organ or bone marrow transplant, autoimmune diseases, and cancer. We defined incident COVID-19 BTI as positive results from laboratory tests or diagnostic codes 14 days after at least 2 doses of mRNA vaccination; and severe COVID-19 BTI as hospitalization, invasive cardiopulmonary support, and/or death. We used propensity scores to match boosted versus nonboosted patients and evaluated hazards of incident and severe COVID-19 BTI using Cox regression after matching.
    Results: Among patients without immune dysfunction, the relative effectiveness of booster (3 doses) after 6 months from the primary (2 doses) vaccination against BTI ranged from 69% to 81% during the Delta-predominant period and from 33% to 39% during the Omicron-predominant period. Relative effectiveness against BTI was lower among patients with immune dysfunction but remained statistically significant in both periods. Boosted patients had lower risk of COVID-19-related hospitalization (hazard ratios [HR] ranged from 0.5 [95% confidence interval {CI}, .48-.53] to 0.63 [95% CI, .56-.70]), invasive cardiopulmonary support, or death (HRs ranged from 0.46 [95% CI, .41-.52] to 0.63 [95% CI, .50-.79]) during both periods.
    Conclusions: Booster vaccines remain effective against severe COVID-19 BTI throughout the Delta- and Omicron-predominant periods, regardless of patients' immune status.
    Language English
    Publishing date 2024-01-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2757767-3
    ISSN 2328-8957
    ISSN 2328-8957
    DOI 10.1093/ofid/ofae019
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Monitoring non-pharmaceutical public health interventions during the COVID-19 pandemic

    Yannan Shen / Guido Powell / Iris Ganser / Qulu Zheng / Chris Grundy / Anya Okhmatovskaia / David L. Buckeridge

    Scientific Data, Vol 8, Iss 1, Pp 1-

    2021  Volume 6

    Abstract: Measuring and monitoring non-pharmaceutical interventions is important yet challenging due to the need to clearly define and encode non-pharmaceutical interventions, to collect geographically and socially representative data, and to accurately document ... ...

    Abstract Measuring and monitoring non-pharmaceutical interventions is important yet challenging due to the need to clearly define and encode non-pharmaceutical interventions, to collect geographically and socially representative data, and to accurately document the timing at which interventions are initiated and changed. These challenges highlight the importance of integrating and triangulating across multiple databases and the need to expand and fund the mandate for public health organizations to track interventions systematically.
    Keywords Science ; Q
    Language English
    Publishing date 2021-08-01T00:00:00Z
    Publisher Nature Portfolio
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Book ; Online: HIT-COVID, a global database tracking public health interventions for COVID-19

    Zheng, Qulu / Sarah V. Leavitt / Jones, Forrest K / Ung, Lawson / Lee, Elizabeth / Andrew Azman

    2020  

    Abstract: Data and Codebook for the HIT-COVID ... ...

    Abstract Data and Codebook for the HIT-COVID Project
    Keywords covid19
    Publishing date 2020-07-10
    Publishing country eu
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Cholera outbreaks in sub-Saharan Africa during 2010-2019: a descriptive analysis.

    Zheng, Qulu / Luquero, Francisco J / Ciglenecki, Iza / Wamala, Joseph F / Abubakar, Abdinasir / Welo, Placide / Hussen, Mukemil / Wossen, Mesfin / Yennan, Sebastian / Keita, Alama / Lessler, Justin / Azman, Andrew S / Lee, Elizabeth C

    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases

    2022  Volume 122, Page(s) 215–221

    Abstract: Background: Cholera remains a public health threat but is inequitably distributed across sub-Saharan Africa. Lack of standardized reporting and inconsistent outbreak definitions limit our understanding of cholera outbreak epidemiology.: Methods: From ...

    Abstract Background: Cholera remains a public health threat but is inequitably distributed across sub-Saharan Africa. Lack of standardized reporting and inconsistent outbreak definitions limit our understanding of cholera outbreak epidemiology.
    Methods: From a database of cholera incidence and mortality, we extracted data from sub-Saharan Africa and reconstructed outbreaks of suspected cholera starting in January 2010 to December 2019 based on location-specific average weekly incidence rate thresholds. We then described the distribution of key outbreak metrics.
    Results: We identified 999 suspected cholera outbreaks in 744 regions across 25 sub-Saharan African countries. The outbreak periods accounted for 1.8 billion person-months (2% of the total during this period) from January 2010 to January 2020. Among 692 outbreaks reported from second-level administrative units (e.g., districts), the median attack rate was 0.8 per 1000 people (interquartile range (IQR), 0.3-2.4 per 1000), the median epidemic duration was 13 weeks (IQR, 8-19), and the median early outbreak reproductive number was 1.8 (range, 1.1-3.5). Larger attack rates were associated with longer times to outbreak peak, longer epidemic durations, and lower case fatality risks.
    Conclusions: This study provides a baseline from which the progress toward cholera control and essential statistics to inform outbreak management in sub-Saharan Africa can be monitored.
    MeSH term(s) Africa South of the Sahara/epidemiology ; Cholera/epidemiology ; Disease Outbreaks ; Humans ; Incidence ; Public Health
    Language English
    Publishing date 2022-05-20
    Publishing country Canada
    Document type Journal Article
    ZDB-ID 1331197-9
    ISSN 1878-3511 ; 1201-9712
    ISSN (online) 1878-3511
    ISSN 1201-9712
    DOI 10.1016/j.ijid.2022.05.039
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: A multi-family cluster of COVID-19 associated with asymptomatic and pre-symptomatic transmission in Jixi City, Heilongjiang, China, 2020.

    Zhang, Hongyang / Hong, Chengcheng / Zheng, Qulu / Zhou, Pengzheng / Zhu, Yuliang / Zhang, Zhongkai / Bi, Qifang / Ma, Ting

    Emerging microbes & infections

    2020  Volume 9, Issue 1, Page(s) 2509–2514

    Abstract: We investigated a multi-family cluster of 22 cases in Jixi, where pre-symptomatic and asymptomatic transmission resulted in at least 41% of household infections of SARS-CoV-2. Our study illustrates the challenge of controlling COVID-19 due to the ... ...

    Abstract We investigated a multi-family cluster of 22 cases in Jixi, where pre-symptomatic and asymptomatic transmission resulted in at least 41% of household infections of SARS-CoV-2. Our study illustrates the challenge of controlling COVID-19 due to the presence of asymptomatic and pre-symptomatic transmission even when extensive testing and contact tracing are conducted.
    MeSH term(s) Adult ; Asymptomatic Diseases ; COVID-19/diagnosis ; COVID-19/epidemiology ; COVID-19/transmission ; COVID-19/virology ; COVID-19 Testing/methods ; Child ; China/epidemiology ; Contact Tracing/statistics & numerical data ; Family ; Female ; Humans ; Male ; Pandemics ; Public Health ; Quarantine/organization & administration ; Reverse Transcriptase Polymerase Chain Reaction ; SARS-CoV-2/genetics ; SARS-CoV-2/isolation & purification ; Severity of Illness Index ; Surveys and Questionnaires
    Language English
    Publishing date 2020-11-23
    Publishing country United States
    Document type Letter
    ZDB-ID 2681359-2
    ISSN 2222-1751 ; 2222-1751
    ISSN (online) 2222-1751
    ISSN 2222-1751
    DOI 10.1080/22221751.2020.1837015
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Book ; Online: HopkinsIDD/hit-covid

    Zheng, Qulu / Jones, Forrest / Ung, Lawson / Leavitt, Sarah V / Labrique, Alain B / Peters, David / Lee, Elizabeth C / Azman, Andrew S

    pre data-descriptor submission

    2020  

    Abstract: Data and Codebook for the HIT-COVID ... ...

    Abstract Data and Codebook for the HIT-COVID Project
    Keywords covid19
    Publishing date 2020-05-18
    Publishing country eu
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: HIT-COVID, a global database tracking public health interventions to COVID-19.

    Zheng, Qulu / Jones, Forrest K / Leavitt, Sarah V / Ung, Lawson / Labrique, Alain B / Peters, David H / Lee, Elizabeth C / Azman, Andrew S

    Scientific data

    2020  Volume 7, Issue 1, Page(s) 286

    Abstract: The COVID-19 pandemic has sparked unprecedented public health and social measures (PHSM) by national and local governments, including border restrictions, school closures, mandatory facemask use and stay at home orders. Quantifying the effectiveness of ... ...

    Abstract The COVID-19 pandemic has sparked unprecedented public health and social measures (PHSM) by national and local governments, including border restrictions, school closures, mandatory facemask use and stay at home orders. Quantifying the effectiveness of these interventions in reducing disease transmission is key to rational policy making in response to the current and future pandemics. In order to estimate the effectiveness of these interventions, detailed descriptions of their timelines, scale and scope are needed. The Health Intervention Tracking for COVID-19 (HIT-COVID) is a curated and standardized global database that catalogues the implementation and relaxation of COVID-19 related PHSM. With a team of over 200 volunteer contributors, we assembled policy timelines for a range of key PHSM aimed at reducing COVID-19 risk for the national and first administrative levels (e.g. provinces and states) globally, including details such as the degree of implementation and targeted populations. We continue to maintain and adapt this database to the changing COVID-19 landscape so it can serve as a resource for researchers and policymakers alike.
    MeSH term(s) Betacoronavirus ; COVID-19 ; Communicable Disease Control/methods ; Coronavirus Infections/prevention & control ; Coronavirus Infections/therapy ; Databases, Factual ; Humans ; Pandemics/prevention & control ; Pneumonia, Viral/prevention & control ; Pneumonia, Viral/therapy ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-08-27
    Publishing country England
    Document type Dataset ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2775191-0
    ISSN 2052-4463 ; 2052-4463
    ISSN (online) 2052-4463
    ISSN 2052-4463
    DOI 10.1038/s41597-020-00610-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: HIT-COVID, a global database tracking public health interventions to COVID-19

    Qulu Zheng / Forrest K. Jones / Sarah V. Leavitt / Lawson Ung / Alain B. Labrique / David H. Peters / Elizabeth C. Lee / Andrew S. Azman / HIT-COVID Collaboration

    Scientific Data, Vol 7, Iss 1, Pp 1-

    2020  Volume 8

    Abstract: Measurement(s) Public Health • Preventive Intervention Technology Type(s) digital curation Factor Type(s) country • date Sample Characteristic - Location global Machine-accessible metadata file describing the reported data: https://doi.org/10.6084/m9 ... ...

    Abstract Measurement(s) Public Health • Preventive Intervention Technology Type(s) digital curation Factor Type(s) country • date Sample Characteristic - Location global Machine-accessible metadata file describing the reported data: https://doi.org/10.6084/m9.figshare.12724058
    Keywords Science ; Q ; covid19
    Language English
    Publishing date 2020-08-01T00:00:00Z
    Publisher Nature Publishing Group
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: HIT-COVID, a global database tracking public health interventions to COVID-19

    Zheng, Qulu / Jones, Forrest K. / Leavitt, Sarah V. / Ung, Lawson / Labrique, Alain B. / Peters, David H. / Lee, Elizabeth C. / Azman, Andrew S.

    Scientific Data

    2020  Volume 7, Issue 1

    Keywords Statistics, Probability and Uncertainty ; Statistics and Probability ; Education ; Library and Information Sciences ; Information Systems ; Computer Science Applications ; covid19
    Language English
    Publisher Springer Science and Business Media LLC
    Publishing country us
    Document type Article ; Online
    ZDB-ID 2775191-0
    ISSN 2052-4463
    ISSN 2052-4463
    DOI 10.1038/s41597-020-00610-2
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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