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  1. Article ; Online: Determining How Coronaviruses Overcome the Interferon and Innate Immune Response.

    Coleman, Christopher M

    Methods in molecular biology (Clifton, N.J.)

    2020  Volume 2203, Page(s) 223–229

    Abstract: All viruses have to overcome the innate immune response in order to establish infection. Methods have been developed to assay if, and how, viruses overcome these responses, and many can be directly applied to coronaviruses. Here, in vitro methods to ... ...

    Abstract All viruses have to overcome the innate immune response in order to establish infection. Methods have been developed to assay if, and how, viruses overcome these responses, and many can be directly applied to coronaviruses. Here, in vitro methods to determine how coronaviruses overcome this response are described.
    MeSH term(s) Animals ; Cell Line ; Coronavirus/growth & development ; Coronavirus/metabolism ; Coronavirus/pathogenicity ; Host-Pathogen Interactions ; Humans ; Immunity, Innate/immunology ; Interferons ; Middle East Respiratory Syndrome Coronavirus/growth & development ; Middle East Respiratory Syndrome Coronavirus/pathogenicity ; RNA, Viral ; Viral Nonstructural Proteins ; Virus Cultivation/methods ; Virus Replication
    Chemical Substances RNA, Viral ; Viral Nonstructural Proteins ; Interferons (9008-11-1)
    Keywords covid19
    Language English
    Publishing date 2020-07-29
    Publishing country United States
    Document type Journal Article
    ISSN 1940-6029
    ISSN (online) 1940-6029
    DOI 10.1007/978-1-0716-0900-2_16
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: A perspective on the impacts of microplastics on mosquito biology and their vectorial capacity.

    Jones, Christopher M / Hughes, Grant L / Coleman, Sylvester / Fellows, Rosie / Quilliam, Richard S

    Medical and veterinary entomology

    2024  Volume 38, Issue 2, Page(s) 138–147

    Abstract: Microplastics (plastic particles <5 mm) permeate aquatic and terrestrial ecosystems and constitute a hazard to animal life. Although much research has been conducted on the effects of microplastics on marine and benthic organisms, less consideration has ... ...

    Abstract Microplastics (plastic particles <5 mm) permeate aquatic and terrestrial ecosystems and constitute a hazard to animal life. Although much research has been conducted on the effects of microplastics on marine and benthic organisms, less consideration has been given to insects, especially those adapted to urban environments. Here, we provide a perspective on the potential consequences of exposure to microplastics within typical larval habitat on mosquito biology. Mosquitoes represent an ideal organism in which to explore the biological effects of microplastics on terrestrial insects, not least because of their importance as an infectious disease vector. Drawing on evidence from other organisms and knowledge of the mosquito life cycle, we summarise some of the more plausible impacts of microplastics including physiological, ecotoxicological and immunological responses. We conclude that although there remains little experimental evidence demonstrating any adverse effect on mosquito biology or pathogen transmission, significant knowledge gaps remain, and there is now a need to quantify the effects that microplastic pollution could have on such an important disease vector.
    MeSH term(s) Animals ; Microplastics/toxicity ; Culicidae/drug effects ; Culicidae/physiology ; Mosquito Vectors/drug effects ; Mosquito Vectors/physiology ; Larva/growth & development ; Larva/drug effects ; Water Pollutants, Chemical/toxicity
    Chemical Substances Microplastics ; Water Pollutants, Chemical
    Language English
    Publishing date 2024-03-12
    Publishing country England
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 286021-1
    ISSN 1365-2915 ; 0269-283X
    ISSN (online) 1365-2915
    ISSN 0269-283X
    DOI 10.1111/mve.12710
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Book: The autisms

    Coleman, Mary / Gillberg, Christopher

    2012  

    Author's details Mary Coleman ; Christopher Gillberg
    Keywords Autistic Disorder / etiology ; Autistic Disorder / physiopathology
    Language English
    Size XII, 389 S. : Ill.
    Edition 4. ed.
    Publisher Oxford Univ. Press
    Publishing place Oxford u.a.
    Publishing country Great Britain
    Document type Book
    Note Includes bibliographical references and indexes
    HBZ-ID HT017103917
    ISBN 978-0-19-973212-8 ; 0-19-973212-4
    Database Catalogue ZB MED Medicine, Health

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  4. Article: The Spatial Ecology of Nuisance Crocodiles: Movement Patterns of Relocated American Crocodiles (

    Coleman, Tyler Steven / Gabel, Wray / Easter, Michael / McGreal, Maggie / Marin, Mahmood Sasa / Garrigos, Davinia Beneyto / Murray, Christopher M

    Animals : an open access journal from MDPI

    2024  Volume 14, Issue 2

    Abstract: Anthropogenic alterations of the environment have increased, highlighting the need for human-wildlife coexistence and conflict mitigation. Spatial ecology, and the use of passive satellite movement technology in particular, has been used to identify ... ...

    Abstract Anthropogenic alterations of the environment have increased, highlighting the need for human-wildlife coexistence and conflict mitigation. Spatial ecology, and the use of passive satellite movement technology in particular, has been used to identify patterns in human-wildlife conflict as a function of shared resources that present potential for dangerous situations. Here, we aim to remotely identify patterns indicative of human-crocodile conflict in Guanacaste, Costa Rica by exploring site fidelity and diverse modes of movement (i.e., land and water) across space between nuisance (relocated) and non-nuisance (wild) crocodiles. Advanced satellite remote sensing technology provided near-constant movement data on individuals at the regional scale. Telonics Iridium SeaTrkr-4370-4 transmitters were used with modified crocodilian fitting. Results indicate that relocated crocodiles exhibited large-scale movements relative to wild crocodiles. Nuisance relocated crocodiles either returned to the area of nuisance or potentially attempted to in short time frames. The results presented here highlight the need for alternative management strategies that facilitate relocation efficacy.
    Language English
    Publishing date 2024-01-22
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2606558-7
    ISSN 2076-2615
    ISSN 2076-2615
    DOI 10.3390/ani14020339
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: The Potential Role of the Light Adjustable Lens in Flanged Intrascleral Haptic Fixation.

    LoBue, Stephen A / Saba, Nicholas / Catapano, Thomas M / Martin, Curtis R / Shelby, Christopher L / Coleman, Wyche T

    Journal of cataract and refractive surgery

    2024  

    Abstract: Purpose: To compare maximum tensile strength between commonly used 3-piece intraocular lens (IOL) for flanged intrascleral haptic fixation (FISHF).: Setting: Willis-Knight Eye Institute.: Design: Laboratory investigation.: Methods: Haptic ... ...

    Abstract Purpose: To compare maximum tensile strength between commonly used 3-piece intraocular lens (IOL) for flanged intrascleral haptic fixation (FISHF).
    Setting: Willis-Knight Eye Institute.
    Design: Laboratory investigation.
    Methods: Haptic tensile strength was compared with MA60AC, CT Lucia 602, AR40E, and the light-adjustable lens (LAL). Haptic strength with a 24D (diopter) IOL was compared across all lenses, as well as a range of 10-30D with the MA60AC. A custom device was created to hold the IOL in correct haptic orientation. The max tension (mean +/- standard deviation) was recorded in newtons (N) when the haptic lost tension or broke.
    Results: CT Lucia was the strongest at 1.53 +/- 0.11 N vs 1.00 +/- 0.15 (MA60AC), 0.87 +/- 0.19 (AR40E), and 0.83 +/- 0.14 N (LAL), P<0.001. The LAL and AR40E were similar to a 9-0 polypropylene suture while being significantly stronger than 10-0 polypropylene suture, P<0.001. No difference in haptic tension for the MA60AC from 10-30D, P>0.05. High magnification revealed the highest haptic fractures for MA60AC at 40% compared to LAL, AR40E, and CT Lucia at 0%. CT Lucia and AR40E had 100% of haptics disinserted from the IOL without any damage compared to 60% LAL and 60% MA60AC. CT Lucia, AR40E, and LAL have a flatter haptic angulation at 5 degrees.
    Conclusion: Haptic strength, durability, and angulation of the LAL may support the possibility of FISHF in the hands of experienced surgeons. However, further testing is strongly recommended to verify if physiologic conditions or light treatments may compromise long-term haptic stability.
    Language English
    Publishing date 2024-04-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 632744-8
    ISSN 1873-4502 ; 0886-3350
    ISSN (online) 1873-4502
    ISSN 0886-3350
    DOI 10.1097/j.jcrs.0000000000001455
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Prediction of In-Hospital Mortality Following Vertebral Fracture Fixation in Patients With Ankylosing Spondylitis or Diffuse Idiopathic Skeletal Hyperostosis: Machine Learning Analysis.

    Cabrera, Andrew / Bouterse, Alexander / Nelson, Michael / Dietrich, Coleman / Razzouk, Jacob / Oyoyo, Udochukwu / Bono, Christopher M / Danisa, Olumide

    International journal of spine surgery

    2024  Volume 18, Issue 1, Page(s) 62–68

    Language English
    Publishing date 2024-03-04
    Publishing country Netherlands
    Document type Journal Article
    ISSN 2211-4599
    ISSN 2211-4599
    DOI 10.14444/8567
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: The Role of Multifocal Intraocular Lens Implantation in Extreme Axial Myopia: A Case Report and Literature Review.

    LoBue, Stephen A / Catapano, Thomas M / DeNaro, Brittany B / Shelby, Christopher / Coleman, Wyche T

    Cureus

    2023  Volume 15, Issue 1, Page(s) e33976

    Abstract: The prevalence of high myopia is rising globally. In addition to an increased risk of retinal detachment, high myopia is associated with earlier cataract formation. Patients with myopia are also often more motivated to become spectacle-independent after ... ...

    Abstract The prevalence of high myopia is rising globally. In addition to an increased risk of retinal detachment, high myopia is associated with earlier cataract formation. Patients with myopia are also often more motivated to become spectacle-independent after a lens procedure. However, the use of multifocal intraocular lens (MfIOL) remains controversial for patients with extreme myopia, which is classified as patients with an axial length >28 mm. Here, we present the case of a 64-year-old patient with visually significant cataract and extreme axial myopia >31 mm in both eyes who desired to be spectacle-independent. A preoperative workup revealed a normal macula with peripheral lattice degeneration. On optical coherence tomography, the macula had a normal fovea contour without the presence of a staphyloma. A thorough peripheral examination was performed by a retina specialist which required no prophylactic treatment. Pentacam analysis demonstrated a low spherical aberration and minimal ectasia risk. Cataract surgery was uneventful with a 5 mm laser capsulotomy centered over the visual axis with the placement of a trifocal intraocular lens. Two months after the cataract surgery, the remaining refractive error was corrected with a laser-assisted in situ keratomileusis enhancement. The patient achieved an uncorrected distance visual acuity of 20/15- and uncorrected near visual acuity of J1+ in both eyes. Overall, this case report and review aims to highlight important preoperative, intraoperative, and postoperative techniques to improve patient outcomes with MfIOL in patients with extreme myopia.
    Language English
    Publishing date 2023-01-19
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.33976
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Body composition changes in physically active individuals consuming ketogenic diets: a systematic review.

    Coleman, Julie L / Carrigan, Christopher T / Margolis, Lee M

    Journal of the International Society of Sports Nutrition

    2021  Volume 18, Issue 1, Page(s) 41

    Abstract: Background: To achieve ideal strength/power to mass ratio, athletes may attempt to lower body mass through reductions in fat mass (FM), while maintaining or increasing fat-free mass (FFM) by manipulating their training regimens and diets. Emerging ... ...

    Abstract Background: To achieve ideal strength/power to mass ratio, athletes may attempt to lower body mass through reductions in fat mass (FM), while maintaining or increasing fat-free mass (FFM) by manipulating their training regimens and diets. Emerging evidence suggests that consumption of high-fat, ketogenic diets (KD) may be advantageous for reducing body mass and FM, while retaining FFM.
    Methods: A systematic review of the literature was conducted using PubMed and Cochrane Library databases to compare the effects of KD versus control diets (CON) on body mass and composition in physically active populations. Randomized and non-randomized studies were included if participants were healthy (free of chronic disease), physically active men or women age ≥ 18 years consuming KD (< 50 g carbohydrate/d or serum or whole blood β-hydroxybutyrate (βhb) > 0.5 mmol/L) for ≥14 days.
    Results: Thirteen studies (9 parallel and 4 crossover/longitudinal) that met the inclusion criteria were identified. Aggregated results from the 13 identified studies show body mass decreased 2.7 kg in KD and increased 0.3 kg in CON. FM decreased by 2.3 kg in KD and 0.3 kg in CON. FFM decreased by 0.3 kg in KD and increased 0.7 kg in CON. Estimated energy balance based on changes in body composition was - 339 kcal/d in KD and 5 kcal/d in CON. Risk of bias identified some concern of bias primarily due to studies which allowed participants to self-select diet intervention groups, as well as inability to blind participants to the study intervention, and/or longitudinal study design.
    Conclusion: KD can promote mobilization of fat stores to reduce FM while retaining FFM. However, there is variance in results of FFM across studies and some risk-of-bias in the current literature that is discussed in this systematic review.
    Language English
    Publishing date 2021-06-05
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2162810-5
    ISSN 1550-2783 ; 1550-2783
    ISSN (online) 1550-2783
    ISSN 1550-2783
    DOI 10.1186/s12970-021-00440-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Prioritizing personal well-being during vascular surgery training.

    Audu, Christopher O / Coleman, Dawn M

    Seminars in vascular surgery

    2019  Volume 32, Issue 1-2, Page(s) 23–26

    Abstract: Burnout among vascular surgery trainees is a significant problem and needs to be addressed at the level of the individual, training program duties, and at each institution. The clinical challenges and patient-oriented care required of a vascular surgeon ... ...

    Abstract Burnout among vascular surgery trainees is a significant problem and needs to be addressed at the level of the individual, training program duties, and at each institution. The clinical challenges and patient-oriented care required of a vascular surgeon generate a level of stress that requires its recognition and development of coping methods to promote well-being and personal happiness. There are ways to minimize burnout during surgical training, including acknowledgment of its symptoms, mentorship, self-care, and access to resources for stress reduction. Crucial factors in maintaining a positive outlook and a sense of meaningful work are faculty entrustability, receptive leadership, celebrating small victories, and recognition that resiliency is a skill that can be learned. Successful vascular surgeon training is a mission that requires everyone involved to actively promote well-being behavior and a supportive work environment. With appropriate implementation of these practices, our training programs can cultivate surgeons who are competent, compassionate, and committed to advancing vascular care.
    MeSH term(s) Adaptation, Psychological ; Burnout, Professional/etiology ; Burnout, Professional/prevention & control ; Burnout, Professional/psychology ; Curriculum ; Education, Medical, Graduate/methods ; Humans ; Interpersonal Relations ; Leadership ; Mental Health ; Mentors ; Resilience, Psychological ; Surgeons/education ; Surgeons/psychology ; Vascular Surgical Procedures/education ; Workplace/psychology
    Language English
    Publishing date 2019-01-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 645131-7
    ISSN 1558-4518 ; 0895-7967
    ISSN (online) 1558-4518
    ISSN 0895-7967
    DOI 10.1053/j.semvascsurg.2019.01.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Experimental study of the purification performance of a MopFan-based photocatalytic air cleaning system.

    Tapia-Brito, Emmanuel / Riffat, James / Wang, Yixin / Wang, Yuhao / Ghaemmaghami, Amir M / Coleman, Christopher M / Erdinç, Mehmet T / Riffat, Saffa

    Building and environment

    2023  Volume 240, Page(s) 110422

    Abstract: Severe acute respiratory syndrome coronavirus (SARS-CoV)-2, the virus that causes the coronavirus disease (COVID)-19, is primarily transmitted through respiratory droplets which linger in enclosed spaces, often exacerbated by HVAC systems. Although ... ...

    Abstract Severe acute respiratory syndrome coronavirus (SARS-CoV)-2, the virus that causes the coronavirus disease (COVID)-19, is primarily transmitted through respiratory droplets which linger in enclosed spaces, often exacerbated by HVAC systems. Although research to improve HVAC handling of SARS-CoV-2 is progressing, currently installed HVAC systems cause problems because they recirculate air and use ineffective filters against virus. This paper details the process of developing a novel method of eliminating air pollutants and suspended pathogens in enclosed spaces using Photocatalytic Oxidation (PCO) technology. It has been previously employed to remove organic contaminants and compounds from air streams using the irradiation of titanium dioxide (TiO
    Language English
    Publishing date 2023-05-16
    Publishing country England
    Document type Journal Article
    ISSN 0360-1323
    ISSN 0360-1323
    DOI 10.1016/j.buildenv.2023.110422
    Database MEDical Literature Analysis and Retrieval System OnLINE

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