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Article ; Online: Prevalence and risk factors for development of recurrent calciphylaxis.

Xia, Joyce / Tan, Alice J / Gabel, Colleen K / Nguyen, Emily D / Chand, Sidharth / Rrapi, Renajd / Dobry, Allison S / Garza-Mayers, Anna Cristina / Ko, Lauren N / Shah, Radhika / St John, Jessica / Nigwekar, Sagar U / Kroshinsky, Daniela

Journal of the American Academy of Dermatology

2024

Language	English
Publishing date	2024-02-19
Publishing country	United States
Document type	Journal Article
ZDB-ID	603641-7
ISSN	1097-6787 ; 0190-9622
ISSN (online)	1097-6787
ISSN	0190-9622
DOI	10.1016/j.jaad.2024.02.019
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Article ; Online: Factors influencing birth setting decision making in the United States: An integrative review.

George, Erin K / Shorten, Allison / Lyons, Karen S / Edmonds, Joyce K

Birth (Berkeley, Calif.)

2022 Volume 49, Issue 3, Page(s) 403–419

Abstract: Background: The United States has the highest perinatal morbidity and mortality (M&M) rates among all high-resource countries in the world. Birth settings (birth center, home, or hospital) influence clinical outcomes, experience of care, and health care ...

Abstract	Background: The United States has the highest perinatal morbidity and mortality (M&M) rates among all high-resource countries in the world. Birth settings (birth center, home, or hospital) influence clinical outcomes, experience of care, and health care costs. Increasing use of low-intervention birth settings can reduce perinatal M&M. This integrative review evaluated factors influencing birth setting decision making among women and birthing people in the United States. Methods: A search strategy was implemented within the CINAHL, PubMed, PsycInfo, and Web of Science databases. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guided the review, and the Johns Hopkins Nursing Evidence-Based Practice model was used to evaluate methodological quality and appraisal of the evidence. The Whittemore and Knafl integrative review framework informed the extraction and analysis of the data and generation of findings. Results: We identified 23 articles that met inclusion criteria. Four analytical themes were generated that described factors that influence birth setting decision making in the United States: "Birth Setting Safety vs. Risk," "Influence of Media, Family, and Friends on Birth Setting Awareness," "Presence or Absence of Choice and Control," and "Access to Options." Discussion: Supporting women and birthing people to make informed decisions by providing information about birth setting options and variations in models of care by birth setting is a critical patient-centered strategy to ensure equitable access to low-intervention birth settings. Policies that expand affordable health insurance to cover midwifery care in all birth settings are needed to enable people to make informed choices about birth location that align with their values, individual pregnancy characteristics, and preferences.
MeSH term(s)	Birth Setting ; Birthing Centers ; Decision Making ; Female ; Humans ; Infant, Newborn ; Midwifery ; Parturition ; Perinatal Death ; Pregnancy ; United States
Language	English
Publishing date	2022-04-20
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	604869-9
ISSN	1523-536X ; 0730-7659
ISSN (online)	1523-536X
ISSN	0730-7659
DOI	10.1111/birt.12640
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Article ; Online: Durable Left Ventricular Assist Device Outflow Graft Obstructions

Carli J. Peters / Robert S. Zhang / Mahesh K. Vidula / Jay Giri / Pavan Atluri / Michael A. Acker / Christian A. Bermúdez / Allison Levin / Kim Urgo / Joyce Wald / Jeremy A. Mazurek / Thomas C. Hanff / Lee R. Goldberg / Dinesh Jagasia / Edo Y. Birati

Journal of Clinical Medicine, Vol 12, Iss 2430, p

Clinical Characteristics and Outcomes

2023 Volume 2430

Abstract: Purpose: We report on the clinical course and management of patients supported with durable implantable LVADs who developed outflow graft obstructions at a large academic center. Methods: We performed a retrospective review of patients receiving LVAD ... ...

Abstract	Purpose: We report on the clinical course and management of patients supported with durable implantable LVADs who developed outflow graft obstructions at a large academic center. Methods: We performed a retrospective review of patients receiving LVAD support from 2012 through 2020. Patients who developed an outflow graft obstruction diagnosed by computed tomography angiography (CTA) or angiogram were identified, and patient characteristics and outcomes were reported. Results: Of the 324 patients supported by LVAD at our institution, 11 patients (3.4%) were diagnosed with outflow graft obstructions. The most common presentation was low flow alarms, which was present in 10/11 patients, and the remaining patient presented with lightheadedness. Patients had minimal LDH elevation with 8/11 presenting with less than 2-fold the upper limit of normal. Transthoracic echocardiograms were not diagnostic, but CTA enabled non-invasive diagnoses in 8/11 of the patients. Three patients with extrinsic compression of the outflow graft successfully underwent endovascular stent placement, and three patients with outflow cannula kinks received supportive care. Of the five patients diagnosed with intraluminal thromboses, one received a heart transplant, one underwent an outflow graft revision, and three received supportive care due to comorbidities. Conclusion: Outflow graft obstructions remain a rare, but serious complication. The true prevalence of this entity is likely underestimated due to the non-specific clinical presentation. CTA is a pivotal non-invasive diagnostic step. Patients with external compression were successfully treated with endovascular stenting.
Keywords	LVAD ; outflow graft ; stenosis ; stent ; Medicine ; R
Subject code	610 ; 616
Language	English
Publishing date	2023-03-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Durable Left Ventricular Assist Device Outflow Graft Obstructions: Clinical Characteristics and Outcomes.

Peters, Carli J / Zhang, Robert S / Vidula, Mahesh K / Giri, Jay / Atluri, Pavan / Acker, Michael A / Bermúdez, Christian A / Levin, Allison / Urgo, Kim / Wald, Joyce / Mazurek, Jeremy A / Hanff, Thomas C / Goldberg, Lee R / Jagasia, Dinesh / Birati, Edo Y

Journal of clinical medicine

2023 Volume 12, Issue 6

Abstract: Purpose: We report on the clinical course and management of patients supported with durable implantable LVADs who developed outflow graft obstructions at a large academic center.: Methods: We performed a retrospective review of patients receiving ... ...

Abstract	Purpose: We report on the clinical course and management of patients supported with durable implantable LVADs who developed outflow graft obstructions at a large academic center. Methods: We performed a retrospective review of patients receiving LVAD support from 2012 through 2020. Patients who developed an outflow graft obstruction diagnosed by computed tomography angiography (CTA) or angiogram were identified, and patient characteristics and outcomes were reported. Results: Of the 324 patients supported by LVAD at our institution, 11 patients (3.4%) were diagnosed with outflow graft obstructions. The most common presentation was low flow alarms, which was present in 10/11 patients, and the remaining patient presented with lightheadedness. Patients had minimal LDH elevation with 8/11 presenting with less than 2-fold the upper limit of normal. Transthoracic echocardiograms were not diagnostic, but CTA enabled non-invasive diagnoses in 8/11 of the patients. Three patients with extrinsic compression of the outflow graft successfully underwent endovascular stent placement, and three patients with outflow cannula kinks received supportive care. Of the five patients diagnosed with intraluminal thromboses, one received a heart transplant, one underwent an outflow graft revision, and three received supportive care due to comorbidities. Conclusion: Outflow graft obstructions remain a rare, but serious complication. The true prevalence of this entity is likely underestimated due to the non-specific clinical presentation. CTA is a pivotal non-invasive diagnostic step. Patients with external compression were successfully treated with endovascular stenting.
Language	English
Publishing date	2023-03-22
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2662592-1
ISSN	2077-0383
ISSN	2077-0383
DOI	10.3390/jcm12062430
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Article ; Online: Comorbid neurotrauma increases neurodegenerative-relevant cognitive, motor, and autonomic dysfunction in patients with REM sleep behavior disorder: A substudy of the North American Prodromal Synucleinopathy Consortium.

Elliott, Jonathan E / Ligman, Brittany R / Bryant-Ekstrand, Mohini D / Keil, Allison T / Powers, Katherine / Olivo, Cosette / Neilson, Lee / Postuma, Ronald B / Pelletier, Amélie / Gagnon, Jean-François / Gan-Or, Ziv / Yu, Eric / Liu, Lang / St Louis, Erik K / Forsberg, Leah K / Fields, Julie A / Ross, Owen A / Huddleston, Daniel E / Bliwise, Donald L /

Avidan, Alon Y / Howell, Michael J / Schenck, Carlos H / McLeland, Jennifer / Criswell, Susan R / Videnovic, Aleksandar / During, Emmanuel H / Miglis, Mitchell G / Shprecher, David R / Lee-Iannotti, Joyce K / Boeve, Bradley F / Ju, Yo-El S / Lim, Miranda M

Sleep

2024

Abstract: Study objectives: Rapid eye movement (REM) sleep behavior disorder (RBD) is strongly associated with phenoconversion to an overt synucleinopathy, e.g., Parkinson's disease (PD), Lewy Body Dementia (LBD), and related disorders. Comorbid traumatic brain ... ...

Abstract	Study objectives: Rapid eye movement (REM) sleep behavior disorder (RBD) is strongly associated with phenoconversion to an overt synucleinopathy, e.g., Parkinson's disease (PD), Lewy Body Dementia (LBD), and related disorders. Comorbid traumatic brain injury (TBI) and posttraumatic stress disorder (PTSD) - henceforth "neurotrauma" (NT) - increase the odds of RBD by ~2.5-fold and is associated with an increased rate of service-connected PD in Veterans. Thus, RBD and NT are both independently associated with PD; however, it is unclear how NT influences neurological function in patients with RBD. Methods: Participants ≥18 years with overnight-polysomnogram-confirmed RBD were enrolled between 8/2018 to 4/2021 through the North American Prodromal Synucleinopathy (NAPS) Consortium. Standardized assessments for RBD, TBI, and PTSD history, as well as cognitive, motor, sensory and autonomic function were completed. This cross-sectional analysis compared cases (n=24; RBD+NT) to controls (n=96; RBD), matched for age (~60 years), sex (15% female), and years of education (~15 years). Results: RBD+NT reported earlier RBD symptom onset (37.5±11.9 vs. 52.2±15.1 years of age) and a more severe RBD phenotype. Similarly, RBD+NT reported more severe anxiety and depression, greater frequency of hypertension, and significantly worse cognitive, motor, and autonomic function compared to RBD. No differences in olfaction or color vision were observed. Conclusion: This cross-sectional, matched case:control study shows individuals with RBD+NT have significantly worse neurological measures related to common features of an overt synucleinopathy. Confirmatory longitudinal studies are ongoing; however, these results suggest RBD+NT may be associated with more advanced neurological symptoms related to an evolving neurodegenerative process.
Language	English
Publishing date	2024-01-05
Publishing country	United States
Document type	Journal Article
ZDB-ID	424441-2
ISSN	1550-9109 ; 0161-8105
ISSN (online)	1550-9109
ISSN	0161-8105
DOI	10.1093/sleep/zsae007
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Zs.A 1475: Show issues

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Article ; Online: Hantavirus Disease and COVID-19.

Joyce, Allison K / Oliver, Tarrah T / Kofman, Aaron D / Talker, Donna L / Safaeian, Shahrokh / Peker Barclift, Deniz / Perricone, Adam J / D'Andrea, Shawn M / Whitesell, Amy N / Yazzie, Del / Guarner, Jeannette / Saleki, Mozafar / Ingall, Glynnis B / Choi, Mary J / Antone-Nez, Ramona

American journal of clinical pathology

2022 Volume 157, Issue 3, Page(s) 470–475

Abstract: Objectives: Navajo Nation is disproportionately affected by hantavirus cardiopulmonary syndrome (HCPS), a severe respiratory disease that can quickly progress to respiratory failure and cardiogenic shock. The initial signs and symptoms of HCPS are ... ...

Abstract	Objectives: Navajo Nation is disproportionately affected by hantavirus cardiopulmonary syndrome (HCPS), a severe respiratory disease that can quickly progress to respiratory failure and cardiogenic shock. The initial signs and symptoms of HCPS are indistinguishable from coronavirus disease 2019 (COVID-19). However, this distinction is critical, as the disease course differs greatly, with most patients with COVID-19 experiencing mild to moderate illness. We set out to determine if the evaluation of peripheral blood smears for five hematopathologic criteria previously identified as hallmarks of hantavirus infection, or "the hantavirus 5-point screen," could distinguish between COVID-19 and HCPS. Methods: The hantavirus 5-point screen was performed on peripheral blood smears from 139 patients positive for COVID-19 seeking treatment from Tséhootsooí Medical Center and two Emory University hospitals. Results: Of these 139 individuals, 136 (98%) received a score of 3/5 or below, indicating low suspicion for HCPS. While thrombocytopenia, one of the key signs of HCPS, was seen in the patients with COVID-19, it was generally mild and remained stable on repeat specimens collected 12 to 24 hours later. Conclusions: Given these findings, the 5-point screen remains a useful rapid screening tool for potential HCPS cases and may be useful to distinguish early HCPS from COVID-19 in HCPS endemic regions.
MeSH term(s)	COVID-19 ; Hantavirus ; Hantavirus Infections/diagnosis ; Hantavirus Pulmonary Syndrome/diagnosis ; Hantavirus Pulmonary Syndrome/epidemiology ; Hantavirus Pulmonary Syndrome/pathology ; Humans ; SARS-CoV-2
Language	English
Publishing date	2022-03-09
Publishing country	England
Document type	Journal Article
ZDB-ID	2944-0
ISSN	1943-7722 ; 0002-9173
ISSN (online)	1943-7722
ISSN	0002-9173
DOI	10.1093/ajcp/aqab155
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Article ; Online: Cardiocutaneous Features of Autosomal Dominant Desmoplakin-Associated Arrhythmogenic Cardiomyopathy.

Hylind, Robyn / Beauséjour-Ladouceur, Virginie / Plovanich, Molly Elizabeth / Helms, Adam / Smith, Eric / Joyce, Emer / Granter, Scott / Stevenson, Lynne Warner / Cirino, Allison L / McDonough, Barbara A / Mostaghimi, Arash / Abrams, Dominic J / Lakdawala, Neal K

Circulation. Genomic and precision medicine

2020 Volume 13, Issue 6, Page(s) e003081

MeSH term(s)	Adolescent ; Adult ; Aged ; Arrhythmogenic Right Ventricular Dysplasia/genetics ; Child ; Desmoplakins/genetics ; Female ; Genes, Dominant ; Humans ; Male ; Middle Aged ; Mutation/genetics ; Skin/pathology ; Young Adult
Chemical Substances	Desmoplakins
Language	English
Publishing date	2020-11-15
Publishing country	United States
Document type	Letter
ISSN	2574-8300
ISSN (online)	2574-8300
DOI	10.1161/CIRCGEN.120.003081
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Article ; Online: Artificial intelligence enables whole-body positron emission tomography scans with minimal radiation exposure.

Wang, Yan-Ran Joyce / Baratto, Lucia / Hawk, K Elizabeth / Theruvath, Ashok J / Pribnow, Allison / Thakor, Avnesh S / Gatidis, Sergios / Lu, Rong / Gummidipundi, Santosh E / Garcia-Diaz, Jordi / Rubin, Daniel / Daldrup-Link, Heike E

European journal of nuclear medicine and molecular imaging

2021 Volume 48, Issue 9, Page(s) 2771–2781

Abstract: Purpose: To generate diagnostic : Methods: We used whole-body : Results: The peak signal-to-noise ratio and structural similarity index were significantly higher, and the normalized root-mean-square error was significantly lower on the AI- ... ...

Abstract	Purpose: To generate diagnostic Methods: We used whole-body Results: The peak signal-to-noise ratio and structural similarity index were significantly higher, and the normalized root-mean-square error was significantly lower on the AI-reconstructed PET images compared to simulated 6.25% dose images (p < 0.001). Compared to the ground-truth standard-dose PET, SUV Conclusions: Our CNN model could generate simulated clinical standard
MeSH term(s)	Artificial Intelligence ; Child ; Fluorodeoxyglucose F18 ; Humans ; Magnetic Resonance Imaging ; Positron-Emission Tomography ; Radiation Exposure ; Whole Body Imaging ; Young Adult
Chemical Substances	Fluorodeoxyglucose F18 (0Z5B2CJX4D)
Language	English
Publishing date	2021-02-01
Publishing country	Germany
Document type	Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
ZDB-ID	8236-3
ISSN	1619-7089 ; 0340-6997 ; 1619-7070
ISSN (online)	1619-7089
ISSN	0340-6997 ; 1619-7070
DOI	10.1007/s00259-021-05197-3
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Article ; Online: Immunologic predictors of vaccine responsiveness in patients with lymphoma and CLL.

Chong, Elise A / Kumashie, Kingsley Gideon / Chong, Emeline R / Fabrizio, Joseph / Gupta, Aditi / Svoboda, Jakub / Barta, Stefan K / Walsh, Kristy M / Napier, Ellen B / Lundberg, Rachel K / Nasta, Sunita D / Gerson, James N / Landsburg, Daniel J / Gonzalez, Joyce / Gaano, Andrew / Weirick, Madison E / McAllister, Christopher M / Awofolaju, Moses / John, Gavin N /

The Journal of infectious diseases

2024

Abstract: Patients with B-cell lymphomas have altered cellular components of vaccine responses due to malignancy and therapy, and the optimal timing of vaccination relative to therapy remains unknown. SARS-CoV-2 vaccines created an opportunity for new insights in ... ...

Abstract	Patients with B-cell lymphomas have altered cellular components of vaccine responses due to malignancy and therapy, and the optimal timing of vaccination relative to therapy remains unknown. SARS-CoV-2 vaccines created an opportunity for new insights in vaccine timing because patients were challenged with a novel antigen across multiple phases of treatment. We studied serologic mRNA vaccine response in retrospective and prospective cohorts with lymphoma and CLL, paired with clinical and research immune parameters. Reduced serologic response was observed more frequently during active therapies, but non-response was also common within observation and post-treatment groups. Total IgA and IgM correlated with successful vaccine response. In individuals treated with CART-19, non-response was associated with reduced B and T follicular helper cells. Predictors of vaccine response varied by disease and therapeutic group, and therefore further studies of immune health during and after cancer therapies are needed to allow individualized vaccine timing.
Language	English
Publishing date	2024-03-04
Publishing country	United States
Document type	Journal Article
ZDB-ID	3019-3
ISSN	1537-6613 ; 0022-1899
ISSN (online)	1537-6613
ISSN	0022-1899
DOI	10.1093/infdis/jiae106
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Article ; Online: Use of Ebola Vaccine: Expansion of Recommendations of the Advisory Committee on Immunization Practices To Include Two Additional Populations - United States, 2021.

MMWR. Morbidity and mortality weekly report

2022 Volume 71, Issue 8, Page(s) 290–292

Abstract: On December 19, 2019, the Food and Drug Administration (FDA) approved rVSVΔG-ZEBOV-GP Ebola vaccine (ERVEBO, Merck) for the prevention of Ebola virus disease (EVD) caused by infection with Ebola virus, species Zaire ebolavirus, in adults aged ≥18 years. ... ...

Abstract	On December 19, 2019, the Food and Drug Administration (FDA) approved rVSVΔG-ZEBOV-GP Ebola vaccine (ERVEBO, Merck) for the prevention of Ebola virus disease (EVD) caused by infection with Ebola virus, species Zaire ebolavirus, in adults aged ≥18 years. In February 2020, the Advisory Committee on Immunization Practices (ACIP) recommended preexposure vaccination with ERVEBO for adults aged ≥18 years in the United States who are at highest risk for potential occupational exposure to Ebola virus because they are responding to an outbreak of EVD, work as health care personnel at federally designated Ebola treatment centers in the United States, or work as laboratorians or other staff members at biosafety level 4 facilities in the United States (1).
MeSH term(s)	Adult ; Advisory Committees ; Centers for Disease Control and Prevention, U.S. ; Ebola Vaccines/administration & dosage ; Health Personnel ; Health Planning Guidelines ; Hemorrhagic Fever, Ebola/prevention & control ; Humans ; Laboratory Personnel ; Occupational Exposure/prevention & control ; United States/epidemiology ; Vaccination
Chemical Substances	Ebola Vaccines
Language	English
Publishing date	2022-02-25
Publishing country	United States
Document type	Journal Article
ZDB-ID	412775-4
ISSN	1545-861X ; 0149-2195
ISSN (online)	1545-861X
ISSN	0149-2195
DOI	10.15585/mmwr.mm7108a2
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