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  1. Article ; Online: Harnessing the natural anti-glycan immune response to limit the transmission of enveloped viruses such as SARS-CoV-2.

    Breiman, Adrien / Ruvën-Clouet, Nathalie / Le Pendu, Jacques

    PLoS pathogens

    2020  Volume 16, Issue 5, Page(s) e1008556

    MeSH term(s) ABO Blood-Group System ; Angiotensin-Converting Enzyme 2 ; Betacoronavirus ; COVID-19 ; Coronavirus Infections/immunology ; Coronavirus Infections/transmission ; Glycosylation ; Humans ; Immunity, Innate ; Pandemics ; Peptidyl-Dipeptidase A ; Pneumonia, Viral/immunology ; Pneumonia, Viral/transmission ; Polysaccharides/immunology ; SARS-CoV-2 ; Spike Glycoprotein, Coronavirus/immunology
    Chemical Substances ABO Blood-Group System ; Polysaccharides ; Spike Glycoprotein, Coronavirus ; spike protein, SARS-CoV-2 ; Peptidyl-Dipeptidase A (EC 3.4.15.1) ; ACE2 protein, human (EC 3.4.17.23) ; Angiotensin-Converting Enzyme 2 (EC 3.4.17.23)
    Keywords covid19
    Language English
    Publishing date 2020-05-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2205412-1
    ISSN 1553-7374 ; 1553-7374
    ISSN (online) 1553-7374
    ISSN 1553-7374
    DOI 10.1371/journal.ppat.1008556
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Harnessing the natural anti-glycan immune response to limit the transmission of enveloped viruses such as SARS-CoV-2.

    Adrien Breiman / Nathalie Ruvën-Clouet / Jacques Le Pendu

    PLoS Pathogens, Vol 16, Iss 5, p e

    2020  Volume 1008556

    Keywords Immunologic diseases. Allergy ; RC581-607 ; Biology (General) ; QH301-705.5 ; covid19
    Language English
    Publishing date 2020-05-01T00:00:00Z
    Publisher Public Library of Science (PLoS)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: COVID-19 et groupes sanguins ABO - Où en est-on ?

    Le Pendu, Jacques / Breiman, Adrien / Deleers, Marie / El Kenz, Hanane / Ruvoën, Nathalie

    Medecine sciences : M/S

    2021  Volume 37, Issue 6-7, Page(s) 565–568

    Title translation COVID-19 and ABO blood types: Where do we stand?
    MeSH term(s) ABO Blood-Group System/immunology ; COVID-19/blood ; Disease Susceptibility ; Humans ; Immunity, Innate ; Risk Factors ; SARS-CoV-2/pathogenicity
    Chemical Substances ABO Blood-Group System
    Language French
    Publishing date 2021-06-03
    Publishing country France
    Document type Journal Article
    ZDB-ID 632733-3
    ISSN 1958-5381 ; 0767-0974
    ISSN (online) 1958-5381
    ISSN 0767-0974
    DOI 10.1051/medsci/2021065
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Microbiota-induced regulatory T cells associate with

    Godefroy, Emmanuelle / Barbé, Laure / Le Moullac-Vaidye, Béatrice / Rocher, Jézabel / Breiman, Adrien / Leuillet, Sébastien / Mariat, Denis / Chatel, Jean-Marc / Ruvoën-Clouet, Nathalie / Carton, Thomas / Jotereau, Francine / Le Pendu, Jacques

    Frontiers in microbiology

    2023  Volume 14, Page(s) 1123803

    Abstract: The FUT2 α1,2fucosyltransferase contributes to the synthesis of fucosylated glycans used as attachment factors by several pathogens, including noroviruses and rotaviruses, that can induce life-threatening gastroenteritis in young children. ...

    Abstract The FUT2 α1,2fucosyltransferase contributes to the synthesis of fucosylated glycans used as attachment factors by several pathogens, including noroviruses and rotaviruses, that can induce life-threatening gastroenteritis in young children.
    Language English
    Publishing date 2023-02-27
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587354-4
    ISSN 1664-302X
    ISSN 1664-302X
    DOI 10.3389/fmicb.2023.1123803
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Harnessing the natural anti-glycan immune response to limit the transmission of enveloped viruses such as SARS-CoV-2

    Breiman, Adrien / Ruvën-Clouet, Nathalie / Le Pendu, Jacques

    PLoS Pathog

    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #327291
    Database COVID19

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  6. Article ; Online: ABO Blood Types and COVID-19: Spurious, Anecdotal, or Truly Important Relationships? A Reasoned Review of Available Data.

    Pendu, Jacques Le / Breiman, Adrien / Rocher, Jézabel / Dion, Michel / Ruvoën-Clouet, Nathalie

    Viruses

    2021  Volume 13, Issue 2

    Abstract: Since the emergence of COVID-19, many publications have reported associations with ABO blood types. Despite between-study discrepancies, an overall consensus has emerged whereby blood group O appears associated with a lower risk of COVID-19, while non-O ... ...

    Abstract Since the emergence of COVID-19, many publications have reported associations with ABO blood types. Despite between-study discrepancies, an overall consensus has emerged whereby blood group O appears associated with a lower risk of COVID-19, while non-O blood types appear detrimental. Two major hypotheses may explain these findings: First, natural anti-A and anti-B antibodies could be partially protective against SARS-CoV-2 virions carrying blood group antigens originating from non-O individuals. Second, O individuals are less prone to thrombosis and vascular dysfunction than non-O individuals and therefore could be at a lesser risk in case of severe lung dysfunction. Here, we review the literature on the topic in light of these hypotheses. We find that between-study variation may be explained by differences in study settings and that both mechanisms are likely at play. Moreover, as frequencies of ABO phenotypes are highly variable between populations or geographical areas, the ABO coefficient of variation, rather than the frequency of each individual phenotype is expected to determine impact of the ABO system on virus transmission. Accordingly, the ABO coefficient of variation correlates with COVID-19 prevalence. Overall, despite modest apparent risk differences between ABO subtypes, the ABO blood group system might play a major role in the COVID-19 pandemic when considered at the population level.
    MeSH term(s) ABO Blood-Group System/blood ; COVID-19/blood ; COVID-19/epidemiology ; COVID-19/microbiology ; Disease Susceptibility/blood ; Disease Susceptibility/epidemiology ; Disease Susceptibility/microbiology ; Disease Susceptibility/pathology ; Humans ; Incidence ; Isoantibodies/blood ; Microbiota ; Odds Ratio ; SARS-CoV-2 ; Thrombosis/blood ; Thrombosis/epidemiology ; Thrombosis/microbiology
    Chemical Substances ABO Blood-Group System ; Isoantibodies
    Language English
    Publishing date 2021-01-22
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 2516098-9
    ISSN 1999-4915 ; 1999-4915
    ISSN (online) 1999-4915
    ISSN 1999-4915
    DOI 10.3390/v13020160
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Harnessing the natural anti-glycan immune response to limit the transmission of enveloped viruses such as SARS-CoV-2

    Breiman, Adrien / Ruvën-Clouet, Nathalie / Le Pendu, Jacques

    PLOS Pathogens

    2020  Volume 16, Issue 5, Page(s) e1008556

    Keywords Immunology ; Genetics ; Molecular Biology ; Microbiology ; Parasitology ; Virology ; covid19
    Language English
    Publisher Public Library of Science (PLoS)
    Publishing country us
    Document type Article ; Online
    ZDB-ID 2205412-1
    ISSN 1553-7374 ; 1553-7366
    ISSN (online) 1553-7374
    ISSN 1553-7366
    DOI 10.1371/journal.ppat.1008556
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Book ; Article ; Online: Harnessing the natural anti-glycan immune response to limit the transmission of enveloped viruses such as SARS-CoV-2

    Breiman, Adrien / Ruvën-Clouet, Nathalie / Le Pendu, Jacques

    https://www.hal.inserm.fr/inserm-02514946 ; 2020

    2020  

    Keywords [SDV.CAN]Life Sciences [q-bio]/Cancer ; covid19
    Language English
    Publishing date 2020-03-23
    Publisher HAL CCSD
    Publishing country fr
    Document type Book ; Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Book ; Article ; Online: Harnessing the natural anti-glycan immune response to limit the transmission of enveloped viruses such as SARS-CoV-2

    Breiman, Adrien / Ruvën-Clouet, Nathalie / Le Pendu, Jacques

    https://www.hal.inserm.fr/inserm-02514946 ; 2020

    2020  

    Keywords [SDV.CAN]Life Sciences [q-bio]/Cancer ; covid19
    Language English
    Publishing date 2020-03-23
    Publisher HAL CCSD
    Publishing country fr
    Document type Book ; Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Book ; Article ; Online: Harnessing the natural anti-glycan immune response to limit the transmission of enveloped viruses such as SARS-CoV-2

    Breiman, Adrien / Ruvën-Clouet, Nathalie / Le Pendu, Jacques

    https://www.hal.inserm.fr/inserm-02514946 ; 2020

    2020  

    Keywords [SDV.CAN]Life Sciences [q-bio]/Cancer ; covid19
    Language English
    Publishing date 2020-03-23
    Publisher HAL CCSD
    Publishing country fr
    Document type Book ; Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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