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  1. Article ; Online: Brazil reports an increased incidence of oropouche and mayaro fever in the amazon region.

    Lorenz, Camila / Chiaravalloti-Neto, Francisco

    Travel medicine and infectious disease

    2024  Volume 58, Page(s) 102692

    MeSH term(s) Humans ; Brazil/epidemiology ; Incidence ; Orthobunyavirus/genetics ; RNA, Viral
    Chemical Substances RNA, Viral
    Language English
    Publishing date 2024-02-02
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2170891-5
    ISSN 1873-0442 ; 1477-8939
    ISSN (online) 1873-0442
    ISSN 1477-8939
    DOI 10.1016/j.tmaid.2024.102692
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Why are there no human West Nile virus outbreaks in South America?

    Lorenz, Camila / Chiaravalloti-Neto, Francisco

    Lancet regional health. Americas

    2022  Volume 12, Page(s) 100276

    Language English
    Publishing date 2022-05-19
    Publishing country England
    Document type Journal Article
    ISSN 2667-193X
    ISSN (online) 2667-193X
    DOI 10.1016/j.lana.2022.100276
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  3. Article ; Online: Why are there no human West Nile virus outbreaks in South America?

    Camila Lorenz / Francisco Chiaravalloti-Neto

    The Lancet Regional Health. Americas, Vol 12, Iss , Pp 100276- (2022)

    2022  

    Keywords Public aspects of medicine ; RA1-1270
    Language English
    Publishing date 2022-08-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Control methods for Aedes aegypti: Have we lost the battle?

    Lorenz, Camila / Chiaravalloti-Neto, Francisco

    Travel medicine and infectious disease

    2022  Volume 49, Page(s) 102428

    Abstract: The past twenty years have been a period of remarkable innovation in Aedes vector control, and several methods with varying success rates have been used. Here we discussed the main intervention categories of vector control applied nowadays and their main ...

    Abstract The past twenty years have been a period of remarkable innovation in Aedes vector control, and several methods with varying success rates have been used. Here we discussed the main intervention categories of vector control applied nowadays and their main weaknesses. It is urgent to have more efficient design and management of control programs, and the requirement for studies to evaluate and compare methods must be prioritised. The world must better articulate actions and cooperate with other sectors beyond health; it is necessary to work together with managers and entomologists in action plans and adapt them to the condition of each region.
    MeSH term(s) Aedes ; Animals ; Dengue/prevention & control ; Humans ; Mosquito Vectors
    Language English
    Publishing date 2022-08-17
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2170891-5
    ISSN 1873-0442 ; 1477-8939
    ISSN (online) 1873-0442
    ISSN 1477-8939
    DOI 10.1016/j.tmaid.2022.102428
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  5. Article ; Online: Spatial analysis of American cutaneous leishmaniasis in the state of Amazonas.

    Santos, Mirely Ferreira Dos / Lorenz, Camila / Chiaravalotti-Neto, Francisco / Lima-Camara, Tamara Nunes

    Revista de saude publica

    2024  Volume 58, Page(s) 11

    Abstract: Objective: To evaluate, using spatial analysis, the occurrence of American Cutaneous Leishmaniasis (ACL) and analyze its association with the municipal human development index (MHDI) and deforestation in the state of Amazonas, Brazil, from 2016 to 2020.! ...

    Abstract Objective: To evaluate, using spatial analysis, the occurrence of American Cutaneous Leishmaniasis (ACL) and analyze its association with the municipal human development index (MHDI) and deforestation in the state of Amazonas, Brazil, from 2016 to 2020.
    Methods: This ecological study, carried out from January 2016 to December 2020, included the 62 municipalities of the state of Amazonas. The incidence rate of ACL was determined in space and time. Using Multiple Linear Regression by Ordinary Least Squares (OLS) and Spatial Autoregressive Regression (SAR) models, the relationship between incidence rates and Human Development Index (HDI) and deforestation was analyzed., The high- and low-risk clusters were identified by employing the Getis-Ord Gi* statistic.
    Results: A total of 7,499 cases of ACL were registered in all 62 municipalities in the state. Most cases were in male (n=5,924; 79.24%), with the greatest frequency in the population aged from 20 to 39 years (n=3,356; 44.7%). The incidence rate in the state of Amazonas was 7.34 cases per 100,000 inhabitants-year, with the municipalities of Rio Preto da Eva and Presidente Figueiredo showing the highest rates (1,377.5 and 817.5 cases per 100,000 population-year, respectively). The ACL cases were clustered into specific areas related to those municipalities with the highest incidence rates. The SAR model revealed a positive relationship between ACL and deforestation.
    Conclusions: The occurrence of ACL was evident in a variety of patterns in the state of Amazonas; the high incidence rates and persistence of this disease in this state were linked to deforestation. The temporal distribution showed variations in the incidence rates during each year. Our results can help optimize the measures needed to prevent and control this disease in the state.
    MeSH term(s) Humans ; Brazil/epidemiology ; Leishmaniasis, Cutaneous/epidemiology ; Incidence ; Spatial Analysis ; Male ; Adult ; Female ; Young Adult ; Adolescent ; Child ; Middle Aged ; Conservation of Natural Resources ; Child, Preschool ; Infant ; Risk Factors ; Socioeconomic Factors
    Language English
    Publishing date 2024-04-19
    Publishing country Brazil
    Document type Journal Article
    ZDB-ID 732179-x
    ISSN 1518-8787 ; 0034-8910
    ISSN (online) 1518-8787
    ISSN 0034-8910
    DOI 10.11606/s1518-8787.2024058005662
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: The use of wing shape for characterising macroevolution in mosquitoes (Diptera: Culicidae)

    Lorenz, Camila / Suesdek, Lincoln

    Infection, genetics, and evolution. 2020 Jan., v. 77

    2020  

    Abstract: The wing form of culicid mosquitoes shows considerable variation among groups: this phenomenon has been addressed by several studies through space-time analyses in mosquito populations, species, and genera. The observed variation results from a ... ...

    Abstract The wing form of culicid mosquitoes shows considerable variation among groups: this phenomenon has been addressed by several studies through space-time analyses in mosquito populations, species, and genera. The observed variation results from a combination of two distinct factors: heredity and phenotypic plasticity. The first is usually related to wing shape, a complex character that may serve as a taxonomic marker in specific cases. We hypothesized that wing shape might be phylogenetically meaningful in Culicidae. In this study, we applied a geometric morphometrical approach based on 18 landmarks in 81 species of mosquitoes, representing 19 different genera, to investigate whether wing shape can help retrieve macroevolutionary patterns or identify any phylogenetic signals. We observed that wing shape differed considerably among groups, especially between Anophelinae and Culicinae subfamilies; thus, some wing shape elements may be synapomorphic. Comparisons among wing consensus after Procrustes superimposition revealed that landmark #1, located between the veins RS and R1, was the most variable. Sabethini tribe was distinguished from other taxa owing to a strong phylogenetic signal of its wings, whereas other culicids presented weaker signals and were not that distinguishable. Evolutionary forces such as natural selection, evolutionary limitation/constraint, or canalization mechanisms might drive the evolution of wing phenotype. These findings suggest that the wing undergoes evolution over long periods, but is not neutral enough to reconstruct the phylogenetic history of these insects. Gene-based studies should be performed to understand the driving forces in wing evolution.
    Keywords Culicidae ; geometry ; infection ; inheritance (genetics) ; natural selection ; phenotype ; phenotypic plasticity ; space and time ; synapomorphy
    Language English
    Dates of publication 2020-01
    Publishing place Elsevier B.V.
    Document type Article
    Note NAL-AP-2-clean
    ZDB-ID 2037068-4
    ISSN 1567-1348
    ISSN 1567-1348
    DOI 10.1016/j.meegid.2019.104052
    Database NAL-Catalogue (AGRICOLA)

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  7. Article ; Online: Impact of climate change on West Nile virus distribution in South America.

    Lorenz, Camila / de Azevedo, Thiago Salomão / Chiaravalloti-Neto, Francisco

    Transactions of the Royal Society of Tropical Medicine and Hygiene

    2022  Volume 116, Issue 11, Page(s) 1043–1053

    Abstract: Background: West Nile virus (WNV) is a vector-borne pathogen of global relevance and is currently the most widely distributed flavivirus causing encephalitis worldwide. Climate conditions have direct and indirect impacts on vector abundance and virus ... ...

    Abstract Background: West Nile virus (WNV) is a vector-borne pathogen of global relevance and is currently the most widely distributed flavivirus causing encephalitis worldwide. Climate conditions have direct and indirect impacts on vector abundance and virus dynamics within the mosquito. The significance of environmental variables as drivers in WNV epidemiology is increasing under the current climate change scenario. In this study we used a machine learning algorithm to model WNV distributions in South America.
    Methods: Our model evaluated eight environmental variables for their contribution to the occurrence of WNV since its introduction in South America in 2004.
    Results: Our results showed that environmental variables can directly alter the occurrence of WNV, with lower precipitation and higher temperatures associated with increased virus incidence. High-risk areas may be modified in the coming years, becoming more evident with high greenhouse gas emission levels. Countries such as Bolivia, Paraguay and several Brazilian areas, mainly in the northeast and midwest regions and the Pantanal biome, will be greatly affected, drastically changing the current WNV distribution.
    Conclusions: Understanding the linkages between climatological and ecological change as determinants of disease emergence and redistribution will help optimize preventive strategies. Increased virus surveillance, integrated modelling and the use of geographically based data systems will provide more anticipatory measures by the scientific community.
    MeSH term(s) Animals ; Humans ; West Nile virus ; West Nile Fever/epidemiology ; Climate Change ; Mosquito Vectors ; Brazil
    Language English
    Publishing date 2022-05-31
    Publishing country England
    Document type Journal Article
    ZDB-ID 441375-1
    ISSN 1878-3503 ; 0035-9203
    ISSN (online) 1878-3503
    ISSN 0035-9203
    DOI 10.1093/trstmh/trac044
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  8. Article ; Online: The use of wing shape for characterising macroevolution in mosquitoes (Diptera: Culicidae).

    Lorenz, Camila / Suesdek, Lincoln

    Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases

    2019  Volume 77, Page(s) 104052

    Abstract: The wing form of culicid mosquitoes shows considerable variation among groups: this phenomenon has been addressed by several studies through space-time analyses in mosquito populations, species, and genera. The observed variation results from a ... ...

    Abstract The wing form of culicid mosquitoes shows considerable variation among groups: this phenomenon has been addressed by several studies through space-time analyses in mosquito populations, species, and genera. The observed variation results from a combination of two distinct factors: heredity and phenotypic plasticity. The first is usually related to wing shape, a complex character that may serve as a taxonomic marker in specific cases. We hypothesized that wing shape might be phylogenetically meaningful in Culicidae. In this study, we applied a geometric morphometrical approach based on 18 landmarks in 81 species of mosquitoes, representing 19 different genera, to investigate whether wing shape can help retrieve macroevolutionary patterns or identify any phylogenetic signals. We observed that wing shape differed considerably among groups, especially between Anophelinae and Culicinae subfamilies; thus, some wing shape elements may be synapomorphic. Comparisons among wing consensus after Procrustes superimposition revealed that landmark #1, located between the veins RS and R1, was the most variable. Sabethini tribe was distinguished from other taxa owing to a strong phylogenetic signal of its wings, whereas other culicids presented weaker signals and were not that distinguishable. Evolutionary forces such as natural selection, evolutionary limitation/constraint, or canalization mechanisms might drive the evolution of wing phenotype. These findings suggest that the wing undergoes evolution over long periods, but is not neutral enough to reconstruct the phylogenetic history of these insects. Gene-based studies should be performed to understand the driving forces in wing evolution.
    MeSH term(s) Animals ; Culicidae/anatomy & histology ; Culicidae/classification ; Female ; Male ; Phenotype ; Phylogeny ; Species Specificity ; Wings, Animal/anatomy & histology
    Language English
    Publishing date 2019-10-25
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2037068-4
    ISSN 1567-7257 ; 1567-1348
    ISSN (online) 1567-7257
    ISSN 1567-1348
    DOI 10.1016/j.meegid.2019.104052
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: COVID-19 and dengue fever: A dangerous combination for the health system in Brazil.

    Lorenz, Camila / Azevedo, Thiago S / Chiaravalloti-Neto, Francisco

    Travel medicine and infectious disease

    2020  Volume 35, Page(s) 101659

    MeSH term(s) Betacoronavirus ; Brazil ; COVID-19 ; Coronavirus Infections ; Dengue ; Humans ; Pandemics ; Pneumonia, Viral ; SARS-CoV-2 ; Singapore
    Keywords covid19
    Language English
    Publishing date 2020-04-09
    Publishing country Netherlands
    Document type Letter ; Comment
    ZDB-ID 2170891-5
    ISSN 1873-0442 ; 1477-8939
    ISSN (online) 1873-0442
    ISSN 1477-8939
    DOI 10.1016/j.tmaid.2020.101659
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  10. Article ; Online: Stress of emergency physicians during helicopter operations: impact of patients' diagnoses, severity of diagnoses, and physicians' work experience.

    Petrowski, Katja / Malkewitz, Camila Paola / Schöniger, Christian / Frank, Mark / Theiler, Lorenz

    BMC emergency medicine

    2023  Volume 23, Issue 1, Page(s) 20

    Abstract: Purpose: Emergency physicians are in danger of developing illnesses due to stress in their demanding work environment. Until today, scholars have not identified stressors or resilience factors that qualify to promote the preservation of emergency ... ...

    Abstract Purpose: Emergency physicians are in danger of developing illnesses due to stress in their demanding work environment. Until today, scholars have not identified stressors or resilience factors that qualify to promote the preservation of emergency physicians' well-being. Therefore, potential influencing variables such as patients' diagnoses, the severity of diagnoses, as well as physicians' work experience have to be considered. The present study aims at investigating emergency physicians in the Helicopter Emergency Medical Service (HEMS)' autonomic nervous system activity during emergency operations in one shift with respect to patients' diagnoses, severity of diagnoses, and physicians' work experience.
    Methods: Measurement of HRV (employing the parameters RMSSD and LF/HF) for 59 EPs (age: M = 39.69, SD = 6.19) was performed during two complete air-rescue-days, the alarm and landing phase being investigated in particular. Besides patients' diagnoses, the National Advisory Committee for Aeronautics Score (NACA) was included as an indicator for severity. Diagnoses' and NACA's effect on HRV were examined using a linear mixed model.
    Results: Both HRV parameters indicate a significant decrease of the parasympathetic nervous system as a function of the diagnoses. Furthermore, high NACA scores (≥ V) predicted a significantly lower HRV. In addition, a lower HRV/RMSSD with increasing work experience was observed as well as a positive association between physicians' work experience and sympathetic activation (LF/HF).
    Conclusion: The present study showed that pediatric diagnoses as well as time-critical diagnoses are most stressful and have the highest impact on the physicians' ANS. This knowledge allows the development of specific training to reduce stress.
    MeSH term(s) Humans ; Child ; Infant ; Air Ambulances ; Aircraft ; Emergency Medical Services ; Physicians ; Linear Models
    Language English
    Publishing date 2023-02-20
    Publishing country England
    Document type Journal Article
    ZDB-ID 2050431-7
    ISSN 1471-227X ; 1471-227X
    ISSN (online) 1471-227X
    ISSN 1471-227X
    DOI 10.1186/s12873-023-00786-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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