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  1. Article ; Online: Bicarbonate: From Physiology to Clinical Practice: Reply.

    Coppola, Silvia / Caccioppola, Alessio / Froio, Sara / Chiumello, Davide

    Anesthesiology

    2023  Volume 139, Issue 4, Page(s) 550

    MeSH term(s) Bicarbonates ; Sodium Bicarbonate
    Chemical Substances Bicarbonates ; Sodium Bicarbonate (8MDF5V39QO)
    Language English
    Publishing date 2023-08-15
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 269-0
    ISSN 1528-1175 ; 0003-3022
    ISSN (online) 1528-1175
    ISSN 0003-3022
    DOI 10.1097/ALN.0000000000004696
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  2. Article: Updates on Glycaemic Control Strategies: A Range of Opportunities after Total Pancreatectomy.

    Pieralice, Silvia / Coppola, Alessandro / Maddaloni, Ernesto

    Journal of clinical medicine

    2023  Volume 12, Issue 9

    Abstract: In the past, indications for total pancreatectomy (TP) were rare, with several concerns about patients' postoperative quality of life due to exocrine and endocrine post-pancreatectomy management [ ... ]. ...

    Abstract In the past, indications for total pancreatectomy (TP) were rare, with several concerns about patients' postoperative quality of life due to exocrine and endocrine post-pancreatectomy management [...].
    Language English
    Publishing date 2023-05-06
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm12093306
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  3. Article ; Online: The intraoperative management of robotic-assisted laparoscopic prostatectomy.

    Chiumello, Davide / Fratti, Isabella / Coppola, Silvia

    Current opinion in anaesthesiology

    2023  Volume 36, Issue 6, Page(s) 657–665

    Abstract: Purpose of review: Robotic-assisted laparoscopic radical prostatectomy has become the second most commonly performed robotic surgical procedure worldwide, therefore, anesthesiologists should be aware of the intraoperative pathophysiological consequences. ...

    Abstract Purpose of review: Robotic-assisted laparoscopic radical prostatectomy has become the second most commonly performed robotic surgical procedure worldwide, therefore, anesthesiologists should be aware of the intraoperative pathophysiological consequences. The aim of this narrative review is to report the most recent updates regarding the intraoperative management of anesthesia, ventilation, hemodynamics and central nervous system, during robotic-assisted laparoscopic radical prostatectomy.
    Recent findings: Surgical innovations and the advent of new technologies make it imperative to optimize the anesthesia management to provide the most holistic approach possible. In addition, an ageing population with an increasing burden of comorbidities requires multifocal attention to reduce the surgical stress.
    Summary: Total intravenous anesthesia (TIVA) and balanced general anesthesia are similar in terms of postoperative complications and hospital stay. Reversal of rocuronium is associated with shorter hospital stay and postanesthesia recovery time. Adequate PEEP levels improve oxygenation and driving pressure, and the use of a single recruitment maneuver after the intubation reduces postoperative pulmonary complications. Restrictive intravenous fluid administration minimizes bladder-urethra anastomosis complications and facial edema. TIVA maintains a better autoregulation compared with balanced general anesthesia. Anesthesiologists should be able to optimize the intraoperative management to improve outcomes.
    Language English
    Publishing date 2023-08-29
    Publishing country United States
    Document type Journal Article
    ZDB-ID 645203-6
    ISSN 1473-6500 ; 0952-7907
    ISSN (online) 1473-6500
    ISSN 0952-7907
    DOI 10.1097/ACO.0000000000001309
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    Zs.A 2564: Show issues Location:
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  4. Article ; Online: Physiology of extracorporeal CO

    Gattinoni, Luciano / Coppola, Silvia / Camporota, Luigi

    Intensive care medicine

    2022  Volume 48, Issue 10, Page(s) 1322–1325

    MeSH term(s) Carbon Dioxide ; Extracorporeal Circulation ; Extracorporeal Membrane Oxygenation ; Humans ; Respiratory Insufficiency
    Chemical Substances Carbon Dioxide (142M471B3J)
    Language English
    Publishing date 2022-08-25
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 80387-x
    ISSN 1432-1238 ; 0340-0964 ; 0342-4642 ; 0935-1701
    ISSN (online) 1432-1238
    ISSN 0340-0964 ; 0342-4642 ; 0935-1701
    DOI 10.1007/s00134-022-06827-6
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  5. Article ; Online: Aspirin in Coronavirus Disease 2019-Related Acute Respiratory Distress Syndrome: An Old, Low-Cost Therapy With a Strong Rationale.

    Coppola, Silvia / Chiumello, Davide

    Anesthesia and analgesia

    2021  Volume 132, Issue 4, Page(s) 927–929

    MeSH term(s) Aspirin/adverse effects ; COVID-19 ; Hospital Mortality ; Humans ; Intensive Care Units ; Respiration, Artificial ; Respiratory Distress Syndrome/diagnosis ; Respiratory Distress Syndrome/therapy ; SARS-CoV-2
    Chemical Substances Aspirin (R16CO5Y76E)
    Language English
    Publishing date 2021-02-24
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 80032-6
    ISSN 1526-7598 ; 0003-2999
    ISSN (online) 1526-7598
    ISSN 0003-2999
    DOI 10.1213/ANE.0000000000005408
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  6. Article: Lung Imaging and Artificial Intelligence in ARDS.

    Chiumello, Davide / Coppola, Silvia / Catozzi, Giulia / Danzo, Fiammetta / Santus, Pierachille / Radovanovic, Dejan

    Journal of clinical medicine

    2024  Volume 13, Issue 2

    Abstract: Artificial intelligence (AI) can make intelligent decisions in a manner akin to that of the human mind. AI has the potential to improve clinical workflow, diagnosis, and prognosis, especially in radiology. Acute respiratory distress syndrome (ARDS) is a ... ...

    Abstract Artificial intelligence (AI) can make intelligent decisions in a manner akin to that of the human mind. AI has the potential to improve clinical workflow, diagnosis, and prognosis, especially in radiology. Acute respiratory distress syndrome (ARDS) is a very diverse illness that is characterized by interstitial opacities, mostly in the dependent areas, decreased lung aeration with alveolar collapse, and inflammatory lung edema resulting in elevated lung weight. As a result, lung imaging is a crucial tool for evaluating the mechanical and morphological traits of ARDS patients. Compared to traditional chest radiography, sensitivity and specificity of lung computed tomography (CT) and ultrasound are higher. The state of the art in the application of AI is summarized in this narrative review which focuses on CT and ultrasound techniques in patients with ARDS. A total of eighteen items were retrieved. The primary goals of using AI for lung imaging were to evaluate the risk of developing ARDS, the measurement of alveolar recruitment, potential alternative diagnoses, and outcome. While the physician must still be present to guarantee a high standard of examination, AI could help the clinical team provide the best care possible.
    Language English
    Publishing date 2024-01-05
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm13020305
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  7. Article ; Online: The evaluation of a non-invasive respiratory monitor in ards patients in supine and prone position.

    Pozzi, Tommaso / Coppola, Silvia / Chiodaroli, Elena / Cucinotta, Federico / Becci, Francesca / Chiumello, Davide

    Journal of clinical monitoring and computing

    2024  

    Abstract: Purpose: The Prone positioning in addition to non invasive respiratory support is commonly used in patients with acute respiratory failure. The aim of this study was to assess the accuracy of an impedance-based non-invasive respiratory volume monitor ( ... ...

    Abstract Purpose: The Prone positioning in addition to non invasive respiratory support is commonly used in patients with acute respiratory failure. The aim of this study was to assess the accuracy of an impedance-based non-invasive respiratory volume monitor (RVM) in supine and in prone position.
    Methods: In sedated, paralyzed and mechanically ventilated patients in volume-controlled mode with acute respiratory distress syndrome scheduled for prone positioning it was measured and compared non-invasively tidal volume and respiratory rate provided by the RVM in supine and, subsequently, in prone position, by maintaining unchanged the ventilatory setting.
    Results: Forty patients were enrolled. No significant difference was found between measurements in supine and in prone position either for tidal volume (p = 0.795; p = 0.302) nor for respiratory rate (p = 0.181; p = 0.604). Comparing supine vs. prone position, the bias and limits of agreements for respiratory rate were 0.12 bpm (-1.4 to 1.6) and 20 mL (-80 to 120) for tidal volume.
    Conclusions: The RVM is accurate in assessing tidal volume and respiratory rate in prone compared to supine position. Therefore, the RVM could be applied in non-intubated patients with acute respiratory failure receiving prone positioning to monitor respiratory function.
    Language English
    Publishing date 2024-03-26
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1418733-4
    ISSN 1573-2614 ; 1387-1307 ; 0748-1977
    ISSN (online) 1573-2614
    ISSN 1387-1307 ; 0748-1977
    DOI 10.1007/s10877-024-01147-0
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    Zs.A 2054: Show issues Location:
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  8. Article ; Online: Extracorporeal cardiopulmonary resuscitation in out of hospital cardiac arrest: Does exist the right patient?

    Chiumello, Davide / Coppola, Silvia

    Resuscitation

    2020  Volume 148, Page(s) 271–272

    MeSH term(s) Cardiopulmonary Resuscitation ; Humans ; Out-of-Hospital Cardiac Arrest
    Language English
    Publishing date 2020-01-22
    Publishing country Ireland
    Document type Editorial ; Comment
    ZDB-ID 189901-6
    ISSN 1873-1570 ; 0300-9572
    ISSN (online) 1873-1570
    ISSN 0300-9572
    DOI 10.1016/j.resuscitation.2020.01.008
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  9. Article ; Online: Gold standard motion analysis system for evaluating jumping performance in rhythmic gymnastics

    Silvia Coppola / Claudia Costa / Rodolfo Vastola

    Journal of Human Sport and Exercise, Vol 18, Iss

    2023  Volume 3

    Abstract: The aim of this study is to investigate the effectiveness, not yet described in the literature, of the gold standard system for motion analysis, to analyse the kinematic and dynamic aspects of the split leap in rhythmic gymnastics performed with and ... ...

    Abstract The aim of this study is to investigate the effectiveness, not yet described in the literature, of the gold standard system for motion analysis, to analyse the kinematic and dynamic aspects of the split leap in rhythmic gymnastics performed with and without the ribbon. The sample consists of six top level gymnasts aged between 13 and 16 (mean 15.1 ± 0.94). The acquisitions were carried out with the integrated multifactorial optoelectronic system BTS Bioengineering. Fifteen passive markers, six BTS Smart-DX cameras, two cameras for video support and seven BTS-6000 force platforms were used. After the acquisition of the gymnasts' anthropometric measurements, a standardized and specific neuromuscular activation was carried out. The software SMART tracker and SMART analyser were used to process and analyse the dynamics and kinematics data. A questionnaire was administered to the gymnasts to collect information regarding training. The results showed no major differences in force impulse, jump amplitude, elevation and flight time between the trials performed with and without ribbon. The experiment conducted demonstrates the effectiveness of using the integrated multifactor optoelectronic system to carry out the kinematic and dynamic analysis of a highly complex sports technique.
    Keywords Performance analysis of sport ; Gold standard system ; Sport performance ; Gymnasts ; Biomechanical evaluation ; Sports medicine ; RC1200-1245
    Subject code 796
    Language English
    Publishing date 2023-07-01T00:00:00Z
    Publisher University of Alicante
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: Short-term effects of small volume saline infusion on acid base equilibrium in critically ill patients.

    Chiumello, Davide / Pozzi, Tommaso / Catozzi, Giulia / Chioccola, Mara / Cucinotta, Federico / Coppola, Silvia

    Minerva anestesiologica

    2024  Volume 90, Issue 4, Page(s) 280–290

    Abstract: Background: Short-term acid-base effects of 0.9% saline solution infusion are not well described. Aim of this study was to assess the effects of a fluid challenge with 0.9% saline in critically ill patients according to the Stewart's approach, which ... ...

    Abstract Background: Short-term acid-base effects of 0.9% saline solution infusion are not well described. Aim of this study was to assess the effects of a fluid challenge with 0.9% saline in critically ill patients according to the Stewart's approach, which allows a precise determination of acid base equilibrium.
    Methods: In 40 mechanically ventilated critically ill patients, acid-base variables according to Stewart's approach were measured before and after 30 minutes from the infusion of 0.5L of 0.9% saline. Patients were divided in saline responder (fractional sodium excretion increase <0.5) and non-responders, and in patients with (estimated glomerular filtration rate >63 mL/min) and without renal impairment.
    Results: After saline infusion, plasma sodium concentration did not change (138 [135-141] vs. 138 [135-140] mEq/L, P=0.646), while chloride concentration significantly increased (102 [100-106] vs. 104 [191-106] mEq/L, P=0.003), reducing strong ion difference (37.0 [34.9-38.0] vs. 35.4 [32.7-37.5] mEq/L, P=0.004) without any impact on pH, due to the concomitant albumin dilution. In saline non-responders, the increase of plasma chloride concentration caused a reduction in strong ion difference, while in saline responders both plasma chloride concentration and strong ion difference remained similar. Patients with and without renal impairment presented a similar acid-base response.
    Conclusions: The infusion of 0.9% saline reduced strong ion difference by increasing plasma chloride concentration, with no effect on pH due to concomitant albumin dilution. Saline non-responders, characterized by the ability to excrete the sodium excess, were more likely to suffer the acidifying effects of saline infusion, while renal function did not affect the acid-base response to saline infusion.
    MeSH term(s) Humans ; Critical Illness ; Male ; Female ; Saline Solution/administration & dosage ; Acid-Base Equilibrium/drug effects ; Middle Aged ; Aged ; Infusions, Intravenous ; Adult ; Fluid Therapy ; Respiration, Artificial
    Chemical Substances Saline Solution
    Language English
    Publishing date 2024-04-01
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 123584-9
    ISSN 1827-1596 ; 0026-4717 ; 0375-9393
    ISSN (online) 1827-1596
    ISSN 0026-4717 ; 0375-9393
    DOI 10.23736/S0375-9393.23.17784-4
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