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Article ; Online: Benzyl isothiocyanate attenuates the hydrogen peroxide-induced interleukin-13 expression through glutathione S-transferase P induction in T lymphocytic leukemia cells.

Tang, Yue / Naito, Sho / Abe-Kanoh, Naomi / Ogawa, Seiji / Yamaguchi, Shu / Zhu, Beiwei / Murata, Yoshiyuki / Nakamura, Yoshimasa

Journal of biochemical and molecular toxicology

2018 Volume 32, Issue 6, Page(s) e22054

Abstract: ... gene expression of a T-helper-2 cytokine, interleukin (IL)-13, in T lymphocytic leukemia Jurkat cells. The 24-h ...

Abstract	We investigated the effect of benzyl isothiocyanate (BITC) on the hydrogen peroxide-induced gene expression of a T-helper-2 cytokine, interleukin (IL)-13, in T lymphocytic leukemia Jurkat cells. The 24-h pretreatment of BITC significantly inhibited the IL-13 expression enhanced by hydrogen peroxide. Although the BITC pretreatment did not change the enhanced level of the phosphorylated c-Jun N-terminal kinase (JNK), it significantly inhibited the nuclear translocation of c-Jun induced by hydrogen peroxide. BITC also increased the protein expression of glutathione S-transferase (GST) isozymes, GSTP1/2, as well as the total GST activity. A GSTP1/2-specific inhibitor, 6-(7-nitro-2,1,3-benzoxadiazol-4-ylthio)hexanol (NBDHEX), significantly counteracted the inhibitory effect of BITC on the hydrogen peroxide-enhanced IL-13 upregulation as well as the c-Jun nuclear translocation. Taken together, these results suggested that BITC inhibits the oxidative stress-mediated IL-13 mRNA expression, possibly through interference of the c-Jun phosphorylation by GSTP.
MeSH term(s)	Cell Nucleus/enzymology ; Enzyme Inhibitors/pharmacology ; Glutathione Transferase/antagonists & inhibitors ; Glutathione Transferase/biosynthesis ; Humans ; Hydrogen Peroxide/toxicity ; Interleukin-13/genetics ; Isoenzymes/antagonists & inhibitors ; Isoenzymes/metabolism ; Isothiocyanates/toxicity ; JNK Mitogen-Activated Protein Kinases/metabolism ; Jurkat Cells ; Oxadiazoles/pharmacology ; Oxidative Stress/drug effects ; Oxidative Stress/genetics ; Phosphorylation ; Protein Transport ; RNA, Messenger/metabolism ; Up-Regulation
Chemical Substances	6-(7-nitro-2,1,3-benzoxadiazol-4-ylthio)hexanol ; Enzyme Inhibitors ; Interleukin-13 ; Isoenzymes ; Isothiocyanates ; Oxadiazoles ; RNA, Messenger ; benzyl isothiocyanate (871J6YOR8Q) ; Hydrogen Peroxide (BBX060AN9V) ; Glutathione Transferase (EC 2.5.1.18) ; JNK Mitogen-Activated Protein Kinases (EC 2.7.11.24)
Language	English
Publishing date	2018-04-18
Publishing country	United States
Document type	Journal Article
ZDB-ID	1410020-4
ISSN	1099-0461 ; 1095-6670
ISSN (online)	1099-0461
ISSN	1095-6670
DOI	10.1002/jbt.22054
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Article: Locating Specimens of Extinct Tiger (Panthera tigris) Subspecies: Javan Tiger (P. T. sondaica), Balinese Tiger (P. T. balica), and Caspian Tiger (P. T. virgata), Including Previously Unpublished Specimens

Yamaguchi, Nobuyuki / Driscoll Carlos A / Werdelin Lars / Abramov Alexei V / Csorba Gabor / Cuisin Jacques / Fernholm Bo / Hiermeier Michael / Hills Daphne / Hunter Luke / Itakura Hiroyuki / Johansson Ulf S / Kascheev Vitaliy / Krohmann Katrin / Martin Thomas / Nowak-Kemp Malgosia / Pavlinov Igor Ya / Renoud Francis / Tomsett Louise /

Mije Steven van der / Zholnerovskaya Elena / Groves Colin / Kitchener Andrew C / Nijman Vincent / Macdonald David W

Mammal study. 2013 Sept., v. 38, no. 3

2013

Abstract: Recent advances in multivariate statistics, and in ancient DNA techniques, have greatly increased understanding of tiger phylogeography. However, regardless of advances in analytical methodology, researchers will continue to need access to specimens for ... ...

Abstract	Recent advances in multivariate statistics, and in ancient DNA techniques, have greatly increased understanding of tiger phylogeography. However, regardless of advances in analytical methodology, researchers will continue to need access to specimens for morphological measurements and sampling for genetic analysis. The tiger has become increasingly endangered, and out of the nine putative tiger subspecies, three (Javan, Balinese, and Caspian) have become extinct in the last 100 years, leaving the specimens kept in natural history collections as the only materials available for research. Frustratingly little information is widely available concerning the specimens of these extinct tiger subspecies. We conducted an extensive search for specimens of extinct tiger subspecies, and also developed a simple on-site method to assign unprovenanced and probable Indonesian specimens to either Javan/Balinese or Sumatran subspecies. We located a total of 88 Javan, 11 Balinese, and 46 Caspian tigers, including seven new Javan tigers, and three Balinese tigers that were not widely known previously. These specimens are critical for research in order to understand the intraspecific phylogeny and evolutionary history of the tiger.
Keywords	DNA ; Panthera tigris sondaica ; genetic techniques and protocols ; multivariate analysis ; natural history ; phylogeny ; phylogeography ; Central Asia ; conservation ; Indonesia ; museum ; Sunda Islands
Language	English
Dates of publication	2013-09
Size	p. 187-198.
Publishing place	UniBio Press
Document type	Article
ZDB-ID	2152177-3
ISSN	1348-6160 ; 1343-4152
ISSN (online)	1348-6160
ISSN	1343-4152
DOI	10.3106%2F041.038.0307
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Article: Frequent expression of P-glycoprotein/MDR1 by nasal T-cell lymphoma cells.

Yamaguchi, M / Kita, K / Miwa, H / Nishii, K / Oka, K / Ohno, T / Shirakawa, S / Fukumoto, M

Cancer

1995 Volume 76, Issue 11, Page(s) 2351–2356

Abstract: ... from peripheral T cells or from natural killer cells. The therapeutic outcome of nasal T-cell lymphoma (NL ... a good response to radiotherapy. To clarify the mechanisms of drug resistance, the expression of P ... glycoprotein (P-gp)/MDR1, which is the product of the multidrug resistance (MDR) 1 gene, and MDR3 mRNA in NL ...

Abstract	Background: Lethal midline granuloma is now considered to be a malignant lymphoma derived from peripheral T cells or from natural killer cells. The therapeutic outcome of nasal T-cell lymphoma (NL) treated by conventional chemotherapy for non-Hodgkin's lymphoma is poor, although some patients have a good response to radiotherapy. To clarify the mechanisms of drug resistance, the expression of P-glycoprotein (P-gp)/MDR1, which is the product of the multidrug resistance (MDR) 1 gene, and MDR3 mRNA in NL cells, were examined. Methods: Ten Japanese patients with NL were studied. Nine of these patients were examined before therapy. P-glycoprotein expression and phenotypes of lymphoma cells were examined by immunohistochemical staining using UIC2 as an anti-P-gp monoclonal antibody. In one case, the Rhodamine-123 efflux test was performed. MDR1 and MDR3 mRNA were detected by reverse transcription polymerase chain reaction. Results: Nine of the 10 patients were P-gp positive. In one of nine, functional P-gp expression was observed. MDR1 mRNA was detected in all seven examined patients with P-gp positive NLs, whereas MDR3 mRNA was negative. Retrospectively, patients who received chemotherapy alone had poorer outcome than those treated by combination chemotherapy after irradiation. Conclusion: The poor prognosis for patients with NL treated with chemotherapy may be explained by P-gp expression of the NL cells.
MeSH term(s)	ATP Binding Cassette Transporter, Subfamily B ; ATP Binding Cassette Transporter, Subfamily B, Member 1/genetics ; ATP-Binding Cassette Transporters/genetics ; Adult ; Antibodies, Monoclonal ; Combined Modality Therapy ; Drug Resistance, Multiple/genetics ; Female ; Fluorescent Antibody Technique, Direct ; Fluorescent Dyes ; Gene Expression Regulation, Neoplastic ; Granuloma, Lethal Midline/genetics ; Granuloma, Lethal Midline/pathology ; Humans ; Killer Cells, Natural/pathology ; Lymphoma, T-Cell/drug therapy ; Lymphoma, T-Cell/genetics ; Lymphoma, T-Cell/pathology ; Lymphoma, T-Cell/radiotherapy ; Male ; Nose Diseases/genetics ; Nose Diseases/pathology ; Nose Neoplasms/drug therapy ; Nose Neoplasms/genetics ; Nose Neoplasms/pathology ; Nose Neoplasms/radiotherapy ; Phenotype ; Polymerase Chain Reaction ; RNA, Messenger/analysis ; RNA, Messenger/genetics ; Retrospective Studies ; Rhodamine 123 ; Rhodamines ; T-Lymphocytes/pathology ; Transcription, Genetic ; Treatment Outcome
Chemical Substances	ATP Binding Cassette Transporter, Subfamily B ; ATP Binding Cassette Transporter, Subfamily B, Member 1 ; ATP-Binding Cassette Transporters ; Antibodies, Monoclonal ; Fluorescent Dyes ; RNA, Messenger ; Rhodamines ; Rhodamine 123 (1N3CZ14C5O) ; multidrug resistance protein 3 (9EI49ZU76O)
Language	English
Publishing date	1995-12-01
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1429-1
ISSN	1097-0142 ; 0008-543X ; 1934-662X
ISSN (online)	1097-0142
ISSN	0008-543X ; 1934-662X
DOI	10.1002/1097-0142(19951201)76:11<2351::aid-cncr2820761125>3.0.co;2-1
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Article: [Stability of house drawing in the H-T-P test].

Yamaguchi, M

Shinrigaku kenkyu : The Japanese journal of psychology

1983 Volume 54, Issue 3, Page(s) 160–166

Abstract: The stability of House Drawing in H-T-P test was examined by administering the test to 38 high ...

Abstract	The stability of House Drawing in H-T-P test was examined by administering the test to 38 high school male students (Group A), 40 high school male students (Group B) and 32 juvenile delinquents (Group C). Group A performed the test two times, two weeks apart. The two sets of drawings were then statistically analysed by the experimenter. And the matching of 20 drawings of the first time with 20 drawings of the second was attempted by four judges. In result, test-retest correlations were significant in the style of drawings and the impression as a whole but not so significant in details. Group B and Group C also performed the test two times but the instruction was changed in the second time. Result showed that the stability of drawings was maintained in Group C but not in Group B. Line pressure, One wall and Window Curtains were stable in drawings of all groups.
MeSH term(s)	Adolescent ; Humans ; Juvenile Delinquency/psychology ; Male ; Projective Techniques
Language	Japanese
Publishing date	1983-08
Publishing country	Japan
Document type	English Abstract ; Journal Article
ZDB-ID	203421-9
ISSN	1884-1082 ; 0021-5236
ISSN (online)	1884-1082
ISSN	0021-5236
DOI	10.4992/jjpsy.54.160
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Article: S100-positive histiocytes in T-cell-dependent area in human lymph nodes express P-glycoprotein.

Nishii, K / Kita, K / Miwa, H / Ohno, T / Yamaguchi, M / Oka, K / Shirakawa, S / Fukumoto, M

Japanese journal of cancer research : Gann

1994 Volume 85, Issue 9, Page(s) 946–951

Abstract: ... to histiocytes in the T-cell-dependent paracortical area. Our results show that P-gp was expressed in histiocytes ... In the present study, we examined P-glycoprotein (P-gp)-expressing cells in human lymph nodes (LN ... The signal intensity of the bands was stronger in samples from T-cell ML LN than in those from LN of reactive ...

Abstract	In the present study, we examined P-glycoprotein (P-gp)-expressing cells in human lymph nodes (LN) from patients with reactive lymph adenitis and various malignant lymphomas (ML). MDR1 mRNA was detected in all reactive LN and in 8 of 10 ML samples examined by reverse transcription polymerase chain reaction (RT-PCR). The signal intensity of the bands was stronger in samples from T-cell ML LN than in those from LN of reactive lymph adenitis and B-cell ML. Immunohistochemistry also showed positive reactivity with cellular components in the LN. The P-gp-positive cells, detected by UIC2, in reactive lymph adenitis and ML samples were large in size in the T-cell-dependent paracortical area in LN. Further, morphological characteristics were similar in UIC2-positive cells between reactive and ML LN. Double staining with UIC2 and a hematopoietic cell lineage-specific monoclonal antibody showed that UIC2-positive cell co-expressed S-100, but not other lymphocyte- and ML cell-specific antigens, indicating that these cells correspond to histiocytes in the T-cell-dependent paracortical area. Our results show that P-gp was expressed in histiocytes but not ML cells in LN, and suggest that this molecule may play an important role in the biological function of histiocytes and/or for maintenance of homeostatic levels in T-cell ML LN.
MeSH term(s)	ATP Binding Cassette Transporter, Subfamily B, Member 1/metabolism ; Gene Expression Regulation, Neoplastic ; Histiocytes/metabolism ; Humans ; Immunoenzyme Techniques ; Lymph Nodes/cytology ; Lymph Nodes/metabolism ; Lymphadenitis/metabolism ; Lymphadenitis/pathology ; Lymphoma/metabolism ; Lymphoma/pathology ; RNA, Messenger/genetics ; RNA, Neoplasm/genetics ; S100 Proteins/metabolism ; T-Lymphocytes/cytology
Chemical Substances	ATP Binding Cassette Transporter, Subfamily B, Member 1 ; RNA, Messenger ; RNA, Neoplasm ; S100 Proteins
Language	English
Publishing date	1994-09
Publishing country	Japan
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	804498-3
ISSN	0910-5050
ISSN	0910-5050
DOI	10.1111/j.1349-7006.1994.tb02973.x
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Article ; Online: Study of the electron-doping mechanism in single-walled carbon nanotubes using dimethylbenzimidazole.

Tanaka, N / Yamaguchi, I / Yamaguchi, R / Fujigaya, T

Faraday discussions

2024 Volume 250, Page(s) 390–399

Abstract: Single-walled carbon nanotubes (SWCNTs) exhibit p-type properties in air, necessitating electron ...

Abstract	Single-walled carbon nanotubes (SWCNTs) exhibit p-type properties in air, necessitating electron doping using n-dopants (
Language	English
Publishing date	2024-03-11
Publishing country	England
Document type	Journal Article
ISSN	1364-5498
ISSN (online)	1364-5498
DOI	10.1039/d3fd00128h
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Article ; Online: Severe Pulmonary Hypertension and Septum Left Shift.

Yamaguchi, Craig T / Moody, Alastair E / Beutler, Bryce D / Lee, James P

Anesthesiology

2023 Volume 139, Issue 3, Page(s) 326–327

MeSH term(s)	Humans ; Hypertension, Pulmonary/diagnostic imaging
Language	English
Publishing date	2023-07-10
Publishing country	United States
Document type	Case Reports ; Journal Article
ZDB-ID	269-0
ISSN	1528-1175 ; 0003-3022
ISSN (online)	1528-1175
ISSN	0003-3022
DOI	10.1097/ALN.0000000000004638
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Article: Low-Temperature Synthesis of Cu-Doped Anatase TiO

Honda, Mitsuhiro / Ochiai, Tsuyoshi / Listiani, Popy / Yamaguchi, Yuma / Ichikawa, Yo

Materials (Basel, Switzerland)

2023 Volume 16, Issue 2

Abstract: Titanium dioxide ( ... ...

Abstract	Titanium dioxide (TiO
Language	English
Publishing date	2023-01-09
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2487261-1
ISSN	1996-1944
ISSN	1996-1944
DOI	10.3390/ma16020639
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Article ; Online: Tmem2 Deficiency Leads to Enamel Hypoplasia and Soft Enamel in Mouse.

Nag, P / Inubushi, T / Sasaki, J I / Murotani, T / Kusano, S / Nakanishi, Y / Shiraishi, Y / Kurosaka, H / Imazato, S / Yamaguchi, Y / Yamashiro, T

Journal of dental research

2023 Volume 102, Issue 10, Page(s) 1162–1171

Abstract: Teeth consist of 3 mineralized tissues: enamel, dentin, and cementum. Tooth malformation, the most common craniofacial anomaly, arises from complex genetic and environmental factors affecting enamel structure, size, shape, and tooth eruption. Hyaluronic ... ...

Abstract	Teeth consist of 3 mineralized tissues: enamel, dentin, and cementum. Tooth malformation, the most common craniofacial anomaly, arises from complex genetic and environmental factors affecting enamel structure, size, shape, and tooth eruption. Hyaluronic acid (HA), a primary extracellular matrix component, contributes to structural and physiological functions in periodontal tissue. Transmembrane protein 2 (TMEM2), a novel cell surface hyaluronidase, has been shown to play a critical role during embryogenesis. In this study, we demonstrate
MeSH term(s)	Mice ; Animals ; Dental Enamel Hypoplasia/genetics ; X-Ray Microtomography ; Dental Enamel/metabolism ; Ameloblasts/metabolism ; Amelogenesis/genetics ; Mice, Knockout ; Membrane Proteins/genetics ; Membrane Proteins/metabolism
Chemical Substances	Tmem2 protein, mouse ; Membrane Proteins
Language	English
Publishing date	2023-07-14
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	80207-4
ISSN	1544-0591 ; 0022-0345
ISSN (online)	1544-0591
ISSN	0022-0345
DOI	10.1177/00220345231182355
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Zs.MO 262: Show issues

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Article ; Online: Differences in Approach and Avoidance Motivation Sensitivities Predicting Participation and Performance in Strength Sport.

Cusimano, Kurtis / Freeman, Paul / Moran, Jason / Yamaguchi, Motonori

Journal of strength and conditioning research

2023 Volume 38, Issue 1, Page(s) 180–184

Abstract: Abstract: Cusimano, K, Freeman, P, Moran, J, and Yamaguchi, M. Differences in approach and ... athletes also providing their Wilks scores as a measure of sporting performance. Independent t tests showed ... significantly higher BIS (MD = 2.37, p = 0.003, 95% CI [0.79, 3.94], d = 0.31) and total BAS (MD = 11.71, p < 0 ...

Abstract	Abstract: Cusimano, K, Freeman, P, Moran, J, and Yamaguchi, M. Differences in approach and avoidance motivation sensitivities predicting participation and performance in strength sport. J Strength Cond Res 38(1): 180-184, 2024-Gray's Reinforcement Sensitivity Theory proposes that individual differences in behavior are due to the sensitivity to 2 brain systems: the behavioral inhibition system (BIS), which regulates aversive emotions to threatening stimuli, and the behavioral approach system (BAS), which regulates positive emotions toward rewarding or nonpunishing stimuli. The current study investigated whether BIS and BAS sensitivity predicts participation and performance in strength sports. A sample of 177 competitive strength athletes (male = 148; female = 29; mean age = 28.68; SD = 6.24 years) and 178 control participants (male = 89; female = 89; mean age = 29.39; SD = 7.42) completed the BIS/BAS scale, with strength athletes also providing their Wilks scores as a measure of sporting performance. Independent t tests showed significantly higher BIS (MD = 2.37, p = 0.003, 95% CI [0.79, 3.94], d = 0.31) and total BAS (MD = 11.71, p < 0.001, 95% CI [9.26, 14.15], d = 1.00) sensitivity in strength athletes than individuals in the control group. A 3-step hierarchical regression analysis revealed that the number of training years (β = 0.506, p < 0 .001), BIS (β = -203, p = 0.005) and BAS drive (β = 0.188, p = 0.012) made significant unique contributions to predicting the Wilks score, with no significant contributions of age, sex, BAS fun seeking, and BAS reward responsiveness. The findings indicate that the overall reward sensitivity (total BAS score) and reward seeking (BAS drive) are associated positively with participation and performance in strength sports, respectively. Given the association of these brain systems to addiction and other psychiatric disorders, the findings could have implications in psychiatric treatment and sporting recruitment.
MeSH term(s)	Humans ; Male ; Female ; Adult ; Motivation ; Reinforcement, Psychology ; Inhibition, Psychological ; Affect ; Reward
Language	English
Publishing date	2023-10-06
Publishing country	United States
Document type	Journal Article
ZDB-ID	1156349-7
ISSN	1533-4287 ; 1064-8011
ISSN (online)	1533-4287
ISSN	1064-8011
DOI	10.1519/JSC.0000000000004710
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