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  1. Book ; Online ; E-Book: Pediatric plastic and reconstructive surgery for primary care

    King, MD, PhD, FAAP, FACS, Timothy W. / Taub, MD, FAAP, FACS, Peter J.

    2020  

    Institution American Academy of Pediatrics, Section on Plastic Surgery,
    Author's details Timothy W. American Academy of Pediatrics, Section on Plastic Surgery ; editors : King, Peter J. Taub
    Keywords Surgery, Plastic
    Subject code 617.95
    Language English
    Size 1 online resource (266 pages) :, illustrations
    Publisher American Academy of Pediatrics
    Publishing place Itasca, Illinois
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 1-61002-395-1 ; 1-61002-394-3 ; 978-1-61002-395-5 ; 978-1-61002-394-8
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article: Sensory Chronic Inflammatory Demyelinating Polyradiculoneuropathy: Neglected Immunotherapy-Responsive Sensory Neuropathy.

    Oh, Shin J / King, Peter

    Journal of clinical neurology (Seoul, Korea)

    2024  

    Abstract: Background and purpose: To report an improvement with immunotherapy in 34 (85%)/40 patients who required an immunotherapy among 56 patients with sensory chronic inflammatory demyelinating polyradiculoneuropathy (CIDP).: Methods: Sensory CIDP was ... ...

    Abstract Background and purpose: To report an improvement with immunotherapy in 34 (85%)/40 patients who required an immunotherapy among 56 patients with sensory chronic inflammatory demyelinating polyradiculoneuropathy (CIDP).
    Methods: Sensory CIDP was diagnosed when two inclusion criteria are met: 1) acquired, chronic progressive or relapsing symmetrical or asymmetrical sensory polyneuropathy that had progressed for >2 months; and 2) definite electrophysiological and/or biopsy evidence of demyelinating neuropathy.
    Results: Fifty-six patients with sensory CIDP were identified. Evidence of demyelination was obtained from by the routine motor nerve conduction study (NCS) in 39 (70%) patients, from a nerve biopsy in 10, and from a near-nerve needle sensory NCS in 7 patients. The most prominent laboratory abnormality was a high protein level in the cerebrospinal fluid in 21 (49%) of 43 tested patients. Immunotherapy was required in 41 (79%) of the 52 followed-up patients. An improvement with immunotherapy was observed in 36 (88%)/41 patients. In three patients, motor weakness developed in 5-8 years' follow-up period and so, their diagnosis was changed to CIDP.
    Conclusions: Sensory CIDP is responded to an immunotherapy in 88% of the treated patients. Sensory CIDP was diagnosed by the routine motor NCS in 70% of patients and by a sural nerve biopsy in 18% of patients. Thus, sensory CIDP should be recognized as a treatable CIDP variant among the different types of "idiopathic sensory neuropathy."
    Language English
    Publishing date 2024-02-05
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 2500489-X
    ISSN 2005-5013 ; 1738-6586
    ISSN (online) 2005-5013
    ISSN 1738-6586
    DOI 10.3988/jcn.2023.0469
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: A Perspective on the Use of Fluorescent Imaging to Reveal Mechanisms of Breakup.

    King-Smith, Peter Ewen / Begley, Carolyn / Braun, Richard J

    Current eye research

    2022  Volume 47, Issue 10, Page(s) 1355–1361

    Abstract: Purpose: ...

    Abstract Purpose:
    MeSH term(s) Coloring Agents ; Dry Eye Syndromes/diagnosis ; Fluorescein ; Humans ; Tears
    Chemical Substances Coloring Agents ; Fluorescein (TPY09G7XIR)
    Language English
    Publishing date 2022-07-21
    Publishing country England
    Document type Journal Article ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 82079-9
    ISSN 1460-2202 ; 0271-3683
    ISSN (online) 1460-2202
    ISSN 0271-3683
    DOI 10.1080/02713683.2022.2098981
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Life-Long Steroid Responsive Familial Myopathy With Docking Protein 7 Mutation.

    Oh, Shin J / King, Peter H / Schindler, Alice

    Journal of clinical neuromuscular disease

    2022  Volume 24, Issue 2, Page(s) 80–84

    Abstract: Abstract: Docking protein 7 (DOK7) congenital myasthenic syndrome (CMS) is characterized by limb-girdle weakness and lack of fluctuating fatigability simulating many familial myopathies. Albuterol is the first line of therapy in view of consistent ... ...

    Abstract Abstract: Docking protein 7 (DOK7) congenital myasthenic syndrome (CMS) is characterized by limb-girdle weakness and lack of fluctuating fatigability simulating many familial myopathies. Albuterol is the first line of therapy in view of consistent improvement. Two brothers with progressive predominant biceps weakness for 1-3 years responded to prednisone treatment for 40-50 years. Various studies including muscle biopsy and many laboratory studies were unsuccessful for the definite diagnosis. Gene study, 40 years after the initial evaluation, confirmed the diagnosis of DOK7 CMS. These are the first reported cases of DOK7 CMS associated with a sustained benefit from corticosteroids.
    MeSH term(s) Humans ; Male ; Albuterol ; Muscle Weakness ; Mutation/genetics ; Myasthenic Syndromes, Congenital/genetics ; Steroids
    Chemical Substances Albuterol (QF8SVZ843E) ; Steroids ; DOK7 protein, human
    Language English
    Publishing date 2022-11-30
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1454947-5
    ISSN 1537-1611 ; 1522-0443
    ISSN (online) 1537-1611
    ISSN 1522-0443
    DOI 10.1097/CND.0000000000000398
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Book: Committed uncertainty in psychotherapy

    Lomas, Peter / King, Lucy

    essays in honour of Peter Lomas

    1999  

    Author's details ed. by Lucy King
    Keywords Psychotherapy
    Language English
    Size XII, 161 S.
    Publisher Whurr
    Publishing place London
    Publishing country Great Britain
    Document type Book
    HBZ-ID HT011230300
    ISBN 1-86156-110-5 ; 978-1-86156-110-7
    Database Catalogue ZB MED Medicine, Health

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  6. Article ; Online: Author response-nonoperative treatment of lateral epicondylitis: a systematic review and meta-analysis.

    Lapner, Peter / Hebert-Davies, Jonah / Pollock, J Whitcomb / Alfonso, Ana / Marsh, Jonathan / King, Graham J W

    JSES international

    2023  Volume 7, Issue 5, Page(s) 883–884

    Language English
    Publishing date 2023-06-30
    Publishing country United States
    Document type Journal Article
    ISSN 2666-6383
    ISSN (online) 2666-6383
    DOI 10.1016/j.jseint.2023.05.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Static Subjective Visual Vertical (SVV) in Patients with Vestibular Migraine.

    Bogle, Jamie M / King, Ashley Zaleski / Deep, Nicholas / Weisskopf, Peter / Starling, Amaal J

    Journal of the American Academy of Audiology

    2023  

    Abstract: Background:  Vestibular migraine (VM) is one of the common causes of episodic dizziness, but it is underdiagnosed and poorly understood. Previous research suggests that otolith reflex pathway performance is often impaired in this patient group, leading ... ...

    Abstract Background:  Vestibular migraine (VM) is one of the common causes of episodic dizziness, but it is underdiagnosed and poorly understood. Previous research suggests that otolith reflex pathway performance is often impaired in this patient group, leading to altered perception of roll plane stimuli. Clinically, this perception can be measured with subjective visual vertical (SVV) testing.
    Purpose:  The aim of this study is to compare static SVV performance (absolute mean SVV tilt, variance) in a cohort of patients diagnosed with VM to results obtained from clinically derived normative data.
    Study design:  Retrospective case review.
    Study sample:  Ninety-four consecutive patients between 18 and 65 years of age diagnosed with VM were included in this comparison to clinically derived normative data.
    Data collection and analysis:  Retrospective chart review was completed. Demographic data, symptom report, and vestibular laboratory results were documented. SVV performance was documented in terms of absolute mean SVV tilt and response variance.
    Results:  Abnormal mean SVV tilt was described in 54% (
    Conclusion:  Absolute mean SVV tilt and response variance are often abnormal in patients diagnosed with VM. These findings support theories suggesting atypical intralabyrinthine integration within the vestibular nuclei and cerebellar nodular pathways.
    Language English
    Publishing date 2023-02-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1132599-9
    ISSN 2157-3107 ; 1050-0545
    ISSN (online) 2157-3107
    ISSN 1050-0545
    DOI 10.1055/a-1938-1161
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Saccade-Responsive Visual Cortical Neurons Do Not Exhibit Distinct Visual Response Properties.

    King, Chase W / Ledochowitsch, Peter / Buice, Michael A / de Vries, Saskia E J

    eNeuro

    2023  Volume 10, Issue 9

    Abstract: Rapid saccadic eye movements are used by animals to sample different parts of the visual scene. Previous work has investigated neural correlates of these saccades in visual cortical areas such as V1; however, how saccade-responsive neurons are ... ...

    Abstract Rapid saccadic eye movements are used by animals to sample different parts of the visual scene. Previous work has investigated neural correlates of these saccades in visual cortical areas such as V1; however, how saccade-responsive neurons are distributed across visual areas, cell types, and cortical layers has remained unknown. Through analyzing 818 1 h experimental sessions from the Allen Brain Observatory, we present a large-scale analysis of saccadic behaviors in head-fixed mice and their neural correlates. We find that saccade-responsive neurons are present across visual cortex, but their distribution varies considerably by transgenically defined cell type, cortical area, and cortical layer. We also find that saccade-responsive neurons do not exhibit distinct visual response properties from the broader neural population, suggesting that the saccadic responses of these neurons are likely not predominantly visually driven. These results provide insight into the roles played by different cell types within a broader, distributed network of sensory and motor interactions.
    MeSH term(s) Animals ; Mice ; Saccades ; Neurons ; Brain ; Visual Cortex
    Language English
    Publishing date 2023-09-15
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2800598-3
    ISSN 2373-2822 ; 2373-2822
    ISSN (online) 2373-2822
    ISSN 2373-2822
    DOI 10.1523/ENEURO.0051-23.2023
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Neuronavigation in endoscopic skull base surgery and the accuracy of different MRI sequences.

    Candy, Nicholas G / Jukes, Alistair K / Patel, Sandy / King, Timothy / Bouras, George / Vrodos, Nick / Wormald, Peter-John / Psaltis, Alkis J

    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia

    2024  Volume 123, Page(s) 203–208

    Abstract: Objective: Neuronavigation is common technology used by skull base teams when performing endoscopic endonasal surgery. A common practice of MRI imagining is to obtain 3D isotopic gadolinium enhanced T1W magnetisation prepared rapid gradient echo (MPRAGE) ...

    Abstract Objective: Neuronavigation is common technology used by skull base teams when performing endoscopic endonasal surgery. A common practice of MRI imagining is to obtain 3D isotopic gadolinium enhanced T1W magnetisation prepared rapid gradient echo (MPRAGE) sequences. These are prone to distortion when undertaken on 3 T magnets. The aim of this project is to compare the in vivo accuracy of MRI sequences between current and new high resolution 3D sequences. The goal is to determine if geometric distortion significantly affects neuronavigation accuracy.
    Methods: Patients were scanned with a 3D T1 MPRAGE sequence, 3D T1 SPACE sequence and a CT stereotactic localisation. Following general anaesthesia, patients were registered on the Stealth Station (Medtronic, USA) using a side mount emitter for Electromagnetic navigation. A variety of surgically relevant anatomical landmarks in the sagittal and coronal plane were selected with real and virtual data points measured.
    Results: A total of 10 patients agreed be enrolled in the study with datapoints collected during surgery. The distance between real and virtual datapoints trended to be lower in SPACE sequences compared to MPRAGE. Paired t test did not demonstrate a significant difference.
    Conclusion: We have demonstrated that navigational accuracy is not significantly affected by the type of MRI sequence selected and that current corrective algorithms are sufficient. Navigational accuracy is affected by many factors, with registration error likely playing the most significant role. Further research involving real time imaging such as endoscopic ultrasound may hopefully address this potential error.
    MeSH term(s) Humans ; Neuronavigation/methods ; Magnetic Resonance Imaging/methods ; Skull Base/surgery ; Skull Base/diagnostic imaging ; Male ; Female ; Middle Aged ; Adult ; Imaging, Three-Dimensional/methods ; Neuroendoscopy/methods ; Aged
    Language English
    Publishing date 2024-04-11
    Publishing country Scotland
    Document type Journal Article
    ZDB-ID 1193674-5
    ISSN 1532-2653 ; 0967-5868
    ISSN (online) 1532-2653
    ISSN 0967-5868
    DOI 10.1016/j.jocn.2024.04.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Adapting adaptive design methods to accelerate adoption of a digital asthma management intervention.

    Bender, Bruce G / Cvietusa, Peter J / Goodrich, Glenn K / King, Diane K / Shoup, Jo Ann

    Translational behavioral medicine

    2023  Volume 13, Issue 3, Page(s) 149–155

    Abstract: Investigators conducting translational research in real-world settings may experience changes that create challenges to the successful completion of the trial as well as post-trial adoption and implementation. Adaptive designs support translational ... ...

    Abstract Investigators conducting translational research in real-world settings may experience changes that create challenges to the successful completion of the trial as well as post-trial adoption and implementation. Adaptive designs support translational research by systematically adapting content and methods to meet the needs of target populations, settings and contexts. This manuscript describes an adaptive implementation research model that provides strategies for changing content, delivery processes, and research methods to correct course when anticipated and unanticipated circumstances occur during a pragmatic trial. The Breathewell Program included two large pragmatic trials of the effectiveness of a digital communication technology intervention to improve symptom management and medication adherence in asthma care. The first trial targeted parents of children with asthma; the second targeted adults with asthma. Adaptations were made iteratively to adjust to dynamic conditions within the healthcare setting, informed by prospectively collected stakeholder input, and were categorized retrospectively by the authors as proactive or reactive. Study outcomes demonstrated improved treatment adherence and clinical efficiency. Kaiser Permanente Colorado, the setting for both studies, adopted the speech recognition intervention into routine care, however, both interventions required numerous adaptations, including changes to target population, intervention content, and internal workflows. Proactive and reactive adaptations assured that both trials were successfully completed. Adaptive research designs will continue to provide an important pathway to move healthcare delivery research into practice while conducting ongoing effectiveness evaluation.
    MeSH term(s) Adult ; Child ; Humans ; Asthma/therapy ; Delivery of Health Care ; Health Services Needs and Demand ; Research Design ; Retrospective Studies
    Language English
    Publishing date 2023-01-24
    Publishing country England
    Document type Adaptive Clinical Trial ; Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 2586893-7
    ISSN 1613-9860 ; 1869-6716
    ISSN (online) 1613-9860
    ISSN 1869-6716
    DOI 10.1093/tbm/ibac093
    Database MEDical Literature Analysis and Retrieval System OnLINE

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