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Article ; Online: The hepatic capsular arteries: imaging features and clinical significance.

Ibukuro, Kenji / Mori, Masaya / Akita, Keiichi

2019 Volume 44, Issue 8, Page(s) 2729–2739

Abstract: Background: Although the anatomical features of the hepatic capsular arteries have been previously reported, the radiological and clinical importance of these arteries has not been well documented.: Imaging findings: We injected barium sulfate into ... ...

Abstract	Background: Although the anatomical features of the hepatic capsular arteries have been previously reported, the radiological and clinical importance of these arteries has not been well documented. Imaging findings: We injected barium sulfate into the intra- and extra-hepatic arteries in cadavers to investigate the hepatic capsular arteries. The web-like hepatic capsular arteries derived from the capsular branch of the peripheral hepatic arteries are called isolated arteries. There were anastomoses between the intra- and extra-hepatic arteries (inferior phrenic artery, superior falciform ligament artery, and cystic artery) through the hepatic capsular arteries. Clinical significance: We reviewed the radiology database and assessed clinical cases. When the hepatic artery is occluded, the collateral vessels, such as the inferior phrenic artery and the superior falciform ligament artery, develop via the hepatic capsular arteries at the right triangular ligament and falciform ligament, respectively. Bleeding from capsular arteries causes extensions of the subcapsular hematoma. Conclusion: The hepatic capsular arteries spread along the hepatic surface and constitute the vascular network throughout the liver. These arteries play an important role in collateral circulation in various clinical situations, as well as subcapsular hematoma.
MeSH term(s)	Arteries/diagnostic imaging ; Barium Sulfate ; Cadaver ; Collateral Circulation ; Computed Tomography Angiography ; Contrast Media ; Hepatic Artery/diagnostic imaging ; Humans ; Liver/blood supply
Chemical Substances	Contrast Media ; Barium Sulfate (25BB7EKE2E)
Language	English
Publishing date	2019-04-25
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	2839786-1
ISSN	2366-0058 ; 2366-004X
ISSN (online)	2366-0058
ISSN	2366-004X
DOI	10.1007/s00261-019-02021-3
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Article ; Online: Comparison between CT volumetry and extracellular volume fraction using liver dynamic CT for the predictive ability of liver fibrosis in patients with hepatocellular carcinoma.

Tago, Kenichiro / Tsukada, Jitsuro / Sudo, Naohiro / Shibutani, Kazu / Okada, Masahiro / Abe, Hayato / Ibukuro, Kenji / Higaki, Tokio / Takayama, Tadatoshi

European radiology

2022 Volume 32, Issue 11, Page(s) 7555–7565

Abstract: Objectives: To compare the predictive ability of liver fibrosis (LF) by CT-volumetry (CTV) for liver and spleen and extracellular volume fraction (ECV) for liver in patients undergoing liver resection.: Methods: We retrospectively analysed 90 ... ...

Abstract	Objectives: To compare the predictive ability of liver fibrosis (LF) by CT-volumetry (CTV) for liver and spleen and extracellular volume fraction (ECV) for liver in patients undergoing liver resection. Methods: We retrospectively analysed 90 consecutive patients who underwent CTV and ECV. Manually placed region-of-interest ECV (manual-ECV), rigid-registration ECV (rigid-ECV), and nonrigid-registration ECV (nonrigid-ECV) were calculated as ECV(%) = (1-haematocrit) × (ΔHU Results: After excluding 10 patients, seventy-eight (97.5%) out of 80 patients had a Child-Pugh score of 5 points, and two (2.5%) patients had a Child-Pugh score of 6 points. AUC of ECV showed no significant difference among manual-ECV, rigid-ECV, and nonrigid-ECV. TLV/BSA, SV/BSA, TLV/SV, and RV/SV had a higher correlation with LF grades than manual-ECV. AUC of SV/BSA was significantly higher than that of manual-ECV in F0-1 vs F2-4 and F0-2 vs F3-4. AUC of SV/BSA (0.76-0.83) was higher than that of manual-ECV (0.61-0.75) for all LF grades, although manual-ECV could differentiate between F0-3 and F4 at high AUC (0.75). Conclusions: In patients undergoing liver resection, SV/BSA is a better method for estimating severe LF grades, although manual-ECV has the ability to estimate cirrhosis (≥ F4). Key points: The splenic volume is a better method for estimating liver fibrosis grades. The extracellular volume fraction is also a candidate for the estimation of severe liver fibrosis.
MeSH term(s)	Humans ; Carcinoma, Hepatocellular/complications ; Carcinoma, Hepatocellular/diagnostic imaging ; Carcinoma, Hepatocellular/pathology ; Retrospective Studies ; Liver Neoplasms/complications ; Liver Neoplasms/diagnostic imaging ; Liver Neoplasms/pathology ; Liver Cirrhosis/complications ; Liver Cirrhosis/diagnostic imaging ; Liver Cirrhosis/pathology ; Liver/diagnostic imaging ; Liver/pathology ; Tomography, X-Ray Computed/methods ; Fibrosis
Language	English
Publishing date	2022-05-20
Publishing country	Germany
Document type	Journal Article
ZDB-ID	1085366-2
ISSN	1432-1084 ; 0938-7994 ; 1613-3749
ISSN (online)	1432-1084
ISSN	0938-7994 ; 1613-3749
DOI	10.1007/s00330-022-08852-x
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Article ; Online: A proposed model on MR elastography for predicting postoperative major complications in patients with hepatocellular carcinoma.

Shibutani, Kazu / Okada, Masahiro / Tsukada, Jitsuro / Hyodo, Tomoko / Ibukuro, Kenji / Abe, Hayato / Matsumoto, Naoki / Midorikawa, Yutaka / Moriyama, Mitsuhiko / Takayama, Tadatoshi

BJR open

2021 Volume 3, Issue 1, Page(s) 20210019

Abstract: ... intraoperative data, and ICG-K value. For an easy application to the prediction model, the continuous variables ...

Abstract	Objective: To develop a model for predicting post-operative major complications in patients with hepatocellular carcinoma (HCC). Methods: In all, 186 consecutive patients with pre-operative MR elastography were included. Complications were categorised using Clavien‒Dindo classification, with major complications defined as ≥Grade 3. Liver-stiffness measurement (LSM) values were measured on elastogram. The indocyanine green clearance rate of liver remnant (ICG-Krem) was based on the results of CT volumetry, intraoperative data, and ICG-K value. For an easy application to the prediction model, the continuous variables were converted to categories. Moreover, logistic regression analysis and fivefold cross-validation were performed. The prediction model's discriminative performance was evaluated using the area under the receiver operating characteristic curve (AUC), and the calibration of the model was assessed by the Hosmer‒Lemeshow test. Results: 43 of 186 patients (23.1%) had major complications. The multivariate analysis demonstrated that LSM, albumin-bilirubin (ALBI) score, intraoperative blood loss, and ICG-Krem were significantly associated with major complications. The median AUC of the five validation subsets was 0.878. The Hosmer-Lemeshow test confirmed no evidence of inadequate fit ( Conclusion: The proposed prediction model can be used to predict post-operative major complications in patients with HCC. Advances in knowledge: The proposed prediction model can be used in routine clinical practice to identify post-operative major complications in patients with HCC and to strategise appropriate treatments of HCC.
Language	English
Publishing date	2021-11-24
Publishing country	England
Document type	Journal Article
ISSN	2513-9878
ISSN (online)	2513-9878
DOI	10.1259/bjro.20210019
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Article ; Online: Predictive value of combined computed tomography volumetry and magnetic resonance elastography for major complications after liver resection.

Shibutani, Kazu / Okada, Masahiro / Tsukada, Jitsuro / Ibukuro, Kenji / Abe, Hayato / Matsumoto, Naoki / Midorikawa, Yutaka / Moriyama, Mitsuhiko / Takayama, Tadatoshi

Abdominal radiology (New York)

2021 Volume 46, Issue 7, Page(s) 3193–3204

Abstract: Purpose: To retrospectively compare the predictive value of computed tomography volumetry (CTV), magnetic resonance elastography (MRE) of the liver, and their combination for major complications after liver resection.: Methods: We enrolled 108 ... ...

Abstract	Purpose: To retrospectively compare the predictive value of computed tomography volumetry (CTV), magnetic resonance elastography (MRE) of the liver, and their combination for major complications after liver resection. Methods: We enrolled 108 consecutive patients who underwent anatomical liver resection for liver tumors and preoperative contrast-enhanced CT and MRE. The future liver remnant (FLR) ratio was calculated by CTV, while the liver stiffness measurement (LSM) was obtained by MRE. FLR ratio alone, LSM alone, and combined FLR ratio and LSM were evaluated to predict major complications (Clavien-Dindo grade ≥ IIIa). Univariate and multivariate analyses of hepatic biochemical parameters and imaging data were performed to identify predictors of major complications. Receiver operating characteristic analyses of FLR ratio, LSM, and their combination were performed, and the sensitivity and specificity were calculated. Results: Twenty-two (20.4%) of the 108 patients experienced major complications. According to multiple regression analysis, the FLR ratio (odds ratio [OR] 0.96, 95% confidence interval [CI] 0.91-0.99, p = 0.040) and LSM (OR 1.72, 95% CI 1.01-2.94, p = 0.047) were independent predictors of major complications. The combined FLR ratio and LSM were predictive of major complications, with an area under the curve (AUC) of 0.818, sensitivity of 68.2%, and specificity of 84.9%. The AUC and specificity for combined FLR ratio and LSM were larger than those for FLR ratio (AUC: 0.711, specificity: 80.2%) and LSM (AUC: 0.793, specificity: 80.2%). Conclusion: Combined CTV and MRE analysis can improve the AUC and specificity for predicting major complications after anatomical liver resection.
MeSH term(s)	Elasticity Imaging Techniques ; Hepatectomy ; Humans ; Liver/diagnostic imaging ; Liver/pathology ; Liver/surgery ; Liver Cirrhosis/pathology ; Retrospective Studies ; Tomography, X-Ray Computed
Language	English
Publishing date	2021-03-08
Publishing country	United States
Document type	Journal Article
ZDB-ID	2839786-1
ISSN	2366-0058 ; 2366-004X
ISSN (online)	2366-0058
ISSN	2366-004X
DOI	10.1007/s00261-021-02991-3
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Article: Vascular anatomy of the pancreas and clinical applications.

Ibukuro, K

International journal of gastrointestinal cancer

2001 Volume 30, Issue 1-2, Page(s) 87–104

Abstract: The development of recent technology, especially the helical computed tomography (CT) scan, allows us to observe small peripancreatic vessels which previously could be demonstrated only by angiography (1), and therefore make three-dimensional (3-D) ... ...

Abstract	The development of recent technology, especially the helical computed tomography (CT) scan, allows us to observe small peripancreatic vessels which previously could be demonstrated only by angiography (1), and therefore make three-dimensional (3-D) volume rendered CT angiographic reconstruction possible (2). The neighboring structures as well as the pancreatic vessels are clearly visualized on the axial CT scan. Therefore, it is necessary to define the peripancreatic vessels on the axial images, as well as on angiography to make an accurate diagnosis of pancreatic disease so that we can also estimate the dynamic flow of the peripancreatic vessels. In this chapter, I would like to use the cadaver dissections of pancreatic vessels to explain each pancreatic vessel based on previous anatomic and radiologic references and finally demonstrate the clinical cases in terms of the pancreatic vessels. The pancreatic arteries and veins are explained based on the anatomic and radiologic references. Principal pancreatic vessels are demonstrated on cadaver dissection. The pancreas head is supplied by the anterior and posterior pancreaticoduodenal arteries forming arcades in the pancreaticoduodenal sulcus and is drained by the pancreaticoduodenal veins. The pancreas body and tail are supplied by the dorsal, inferior, and caudate pancreatic arteries, and are drained by the inferior and left pancreatic veins. Clinical applications in terms of the pancreatic vessels such as basis for interpretation of the angiography and the CT scan, treatment of pancreatitis and pancreatic cancer, detection of small insulinoma are stated.
MeSH term(s)	Angiography/methods ; Cadaver ; Humans ; Pancreas/anatomy & histology ; Pancreas/blood supply ; Pancreas/diagnostic imaging ; Pancreatic Neoplasms/blood supply ; Pancreatic Neoplasms/diagnosis ; Pancreatic Neoplasms/diagnostic imaging ; Tomography, X-Ray Computed/methods
Language	English
Publishing date	2001
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	2094727-6
ISSN	1537-3649 ; 0169-4197
ISSN	1537-3649 ; 0169-4197
DOI	10.1385/IJGC:30:1-2:087
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Article ; Online: Protective effect against repeat adverse reactions to iodinated contrast medium: Premedication vs. changing the contrast medium.

Abe, Shoko / Fukuda, Hozumi / Tobe, Kimiko / Ibukuro, Kenji

European radiology

2015 Volume 26, Issue 7, Page(s) 2148–2154

Abstract: Objectives: The purpose of this study was to assess the protective effect of premedication and changing contrast media (CM) against repeat adverse reactions (ARs) to iodinated CM.: Methods: Between January 2006 and September 2014, 771 cases with ... ...

Abstract	Objectives: The purpose of this study was to assess the protective effect of premedication and changing contrast media (CM) against repeat adverse reactions (ARs) to iodinated CM. Methods: Between January 2006 and September 2014, 771 cases with previous ARs to CM were administered CM. The same CM that had caused ARs previously was administered to 491 cases (220 without premedication [defined as the control group], and 271 with premedication [the premedication alone group]). A different CM from the previous CM was given to 280 cases (58 without premedication [the changing CM alone group], and 222 with premedication [the premedication and changing CM group]). Results: The control group had 61 repeat ARs (27.7%). The premedication alone group had 47 ARs (17.3%, p<0.01). The changing CM alone group had 3 ARs (5.2%, p<0.001). Three ARs (7.9%) were observed in 38 cases changing from one to another low-osmolar nonionic CM. Twenty cases with previous ARs to the high-osmolar CM and to the low-osmolar ionic CM showed no ARs. The premedication and changing CM group had 6 ARs (2.7%, p<0.001). Conclusion: Premedication prior to contrast for patients with previous ARs may be protective, however, changing CM was more effective. Key points: • In patients with previous adverse reactions, changing contrast media is recommended. • Premedication is unnecessary against previous reactions to high-osmolar or ionic CM. • Changing from one to another low-osmolar non-ionic CM may be effective.
MeSH term(s)	Adult ; Aged ; Aged, 80 and over ; Contrast Media/adverse effects ; Female ; Gadolinium DTPA/adverse effects ; Humans ; Image Enhancement ; Iohexol/adverse effects ; Iopamidol/adverse effects ; Male ; Middle Aged ; Premedication/methods ; Retrospective Studies ; Young Adult
Chemical Substances	Contrast Media ; Iohexol (4419T9MX03) ; Iopamidol (JR13W81H44) ; Gadolinium DTPA (K2I13DR72L)
Language	English
Publishing date	2015-10-01
Publishing country	Germany
Document type	Journal Article
ZDB-ID	1085366-2
ISSN	1432-1084 ; 0938-7994 ; 1613-3749
ISSN (online)	1432-1084
ISSN	0938-7994 ; 1613-3749
DOI	10.1007/s00330-015-4028-1
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Article ; Online: The vascular anatomy of the ligaments of the liver: gross anatomy, imaging and clinical applications.

Ibukuro, Kenji / Fukuda, Hozumi / Tobe, Kimiko / Akita, Keiichi / Takeguchi, Takaya

The British journal of radiology

2016 Volume 89, Issue 1064, Page(s) 20150925

Abstract: The vessels that communicate between the liver and adjacent structures require bridges between them. The bridges comprise the ligaments of the liver as follows: the falciform ligament, right and left coronary ligaments, lesser omentum including the ... ...

Abstract	The vessels that communicate between the liver and adjacent structures require bridges between them. The bridges comprise the ligaments of the liver as follows: the falciform ligament, right and left coronary ligaments, lesser omentum including the hepatogastric ligament and hepatoduodenal ligament. Each ligament has specific communications between the intrahepatic and extrahapetic vessels. The venous communications called as the portosystemic shunt would become apparent in patients with portal hypertension, intrahepatic portal vein thrombosis and superior vena cava syndrome. The location of the venous communication is related to the pseudolesion or focal enhancement of the liver demonstrated on the CT scan. The arterial communications called collateral vascularization would become apparent in patients with hepatic artery occlusion, especially post-transhepatic arterial embolization, or in patients with the hepatic tumour abutting diaphragm. The knowledge of these collateral arteries is necessary to accomplish the effective transarterial embolization for the hepatic tumours. We reviewed the vessels in these ligaments using contrast-enhanced CT scans and angiography and discussed the clinical applications. Cadaver dissection photos were included as supplementary images for readers to recognize the actual spatial anatomy of the vessel in each ligament.
Language	English
Publishing date	2016-05-10
Publishing country	England
Document type	Journal Article
ZDB-ID	2982-8
ISSN	1748-880X ; 0007-1285
ISSN (online)	1748-880X
ISSN	0007-1285
DOI	10.1259/bjr.20150925
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Article ; Online: Spatial anatomy of the round ligament, gallbladder, and intrahepatic vessels in patients with right-sided round ligament of the liver.

Ibukuro, Kenji / Takeguchi, Takaya / Fukuda, Hozumi / Abe, Shoko / Tobe, Kimiko

Surgical and radiologic anatomy : SRA

2016 Volume 38, Issue 9, Page(s) 1061–1067

Abstract: Purpose: To analyze the vascular structure of the liver in patients with a right-sided round ligament.: Methods: We reviewed 16 patients with a right-sided round ligament and 3 polysplenia and situs inversus patients with a left-sided round ligament ... ...

Abstract	Purpose: To analyze the vascular structure of the liver in patients with a right-sided round ligament. Methods: We reviewed 16 patients with a right-sided round ligament and 3 polysplenia and situs inversus patients with a left-sided round ligament who underwent multidetector row CT with contrast media. The patient population consisted of 13 men and 6 women (mean 62 years). We analyzed the axial and volume-rendered images for the location of the round ligament, gallbladder, portal veins, hepatic veins, and hepatic artery. The following imaging findings for the patients with polysplenia and situs inversus were horizontally reversed. Results: The prevalence of a right-sided round ligament with and without polysplenia was 75 and 0.11 %, respectively. The gallbladder was located to the right, below, and left of the round ligament in 27.7, 38.8 and 33.3 %, respectively. Independent branching of the right posterior portal vein was noted in 57.8 %. PV4 was difficult to identify in 36.8 %. The middle hepatic vein was located to the left of the round ligament. Two branching patterns for the lateral and medial branches of the right anterior hepatic artery were noted: the common (44.4 %) and separated types (55.5 %). Both of the right anterior hepatic artery and portal vein ramified into two segments; the lateral segment with many branches and the medial segment with a few branches. Conclusions: The right-sided round ligament divided the right anterior section into the lateral and medial segments based on the portal vein and hepatic artery anatomy.
MeSH term(s)	Adolescent ; Adult ; Aged ; Aged, 80 and over ; Anatomic Variation ; Child ; Female ; Gallbladder/abnormalities ; Gallbladder/diagnostic imaging ; Humans ; Liver/blood supply ; Liver/diagnostic imaging ; Male ; Middle Aged ; Radiography, Abdominal/statistics & numerical data ; Round Ligament of Liver/abnormalities ; Round Ligament of Liver/diagnostic imaging ; Spleen/abnormalities ; Spleen/diagnostic imaging ; Young Adult
Language	English
Publishing date	2016-11
Publishing country	Germany
Document type	Journal Article
ZDB-ID	632839-8
ISSN	1279-8517 ; 0930-312X ; 0930-1038
ISSN (online)	1279-8517
ISSN	0930-312X ; 0930-1038
DOI	10.1007/s00276-016-1674-1
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Article ; Online: Probing hole spin transport of disorder quantum dots via Pauli spin-blockade in standard silicon transistors.

Hillier, Joseph / Ono, Keiji / Ibukuro, Kouta / Liu, Fayong / Li, Zuo / Husain Khaled, Muhammad / Nicholas Rutt, Harvey / Tomita, Isao / Tsuchiya, Yoshishige / Ishibashi, Koji / Saito, Shinichi

Nanotechnology

2021 Volume 32, Issue 26

Abstract: Single hole transport and spin detection is achievable in standard p-type silicon transistors owing to the strong orbital quantization of disorder based quantum dots. Through the use of the well acting as a pseudo-gate, we discover the formation of a ... ...

Abstract	Single hole transport and spin detection is achievable in standard p-type silicon transistors owing to the strong orbital quantization of disorder based quantum dots. Through the use of the well acting as a pseudo-gate, we discover the formation of a double-quantum dot system exhibiting Pauli spin-blockade and investigate the magnetic field dependence of the leakage current. This enables attributes that are key to hole spin state control to be determined, where we calculate a tunnel coupling
Language	English
Publishing date	2021-04-07
Publishing country	England
Document type	Journal Article
ZDB-ID	1362365-5
ISSN	1361-6528 ; 0957-4484
ISSN (online)	1361-6528
ISSN	0957-4484
DOI	10.1088/1361-6528/abef91
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Article ; Online: Isolated Arteries Originating from the Intrahepatic Arteries: Anatomy, Function, and Importance in Intervention.

Yoshida, Kotaro / Matsui, Osamu / Miyayama, Shiro / Ibukuro, Kenji / Yoneda, Norihide / Inoue, Dai / Kozaka, Kazuto / Minami, Tetsuya / Koda, Wataru / Gabata, Toshifumi

Journal of vascular and interventional radiology : JVIR

2018 Volume 29, Issue 4, Page(s) 531–537.e1

Abstract: Isolated hepatic arteries are defined as hepatic terminal arterioles that are not accompanied by portal venules or bile ductules and penetrate the liver parenchyma and distribute to the hepatic capsule and intrahepatic hepatic veins. Abundant ... ...

Abstract	Isolated hepatic arteries are defined as hepatic terminal arterioles that are not accompanied by portal venules or bile ductules and penetrate the liver parenchyma and distribute to the hepatic capsule and intrahepatic hepatic veins. Abundant communications exist between intra- and extrahepatic arteries through isolated arteries and capsular arterial plexus. They play a principal role in the development of subcapsular hemorrhage and arterial collateral formation following transcatheter arterial chemoembolization for liver cancers. The anatomy, function, and clinical importance of isolated hepatic arteries in interventional radiology, especially regarding subcapsular hemorrhage and arterial collateral formation, are highlighted in this article.
MeSH term(s)	Arterioles/anatomy & histology ; Collateral Circulation ; Hepatic Artery/anatomy & histology ; Humans ; Radiography, Interventional
Language	English
Publishing date	2018-02-22
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	1137756-2
ISSN	1535-7732 ; 1051-0443
ISSN (online)	1535-7732
ISSN	1051-0443
DOI	10.1016/j.jvir.2017.12.002
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