LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 524

Search options

  1. Article ; Online: Investigating the mechanisms of drug resistance and prognosis in ovarian cancer using single-cell RNA sequencing and bulk RNA sequencing.

    Liu, Pengfei / Liu, Jinbao / Liu, Jinxing / Yu, Xiao

    Aging

    2024  Volume 16, Issue 5, Page(s) 4736–4758

    Abstract: Ovarian cancer stands as a prevalent malignancy within the realm of gynecology, and the emergence of resistance to chemotherapeutic agents remains a pivotal impediment to both prognosis and treatment. Through a single-cell level investigation, we ... ...

    Abstract Ovarian cancer stands as a prevalent malignancy within the realm of gynecology, and the emergence of resistance to chemotherapeutic agents remains a pivotal impediment to both prognosis and treatment. Through a single-cell level investigation, we scrutinize the drug resistance and mitotic activity of the core tumor cells in ovarian cancer. Our study revisits the interrelationships and temporal trajectories of distinct epithelial cells (EPCs) subpopulations, while identifying genes associated with ovarian cancer prognosis. Notably, our findings establish a strong association between the drug resistance of EPCs and oxidative phosphorylation pathways. Subsequently, through subpopulation and temporal trajectory analysis, we confirm the intermediate position of EPCs subpopulation C0. Furthermore, we delve into the immunological functions and differentially expressed genes associated with the prognosis of C0, shedding light on the potential for constructing novel ovarian cancer prognosis models and identifying new therapeutic targets.
    MeSH term(s) Humans ; Female ; Drug Resistance, Neoplasm/genetics ; Ovarian Neoplasms/drug therapy ; Ovarian Neoplasms/genetics ; Ovarian Neoplasms/pathology ; Prognosis ; Epithelial Cells/metabolism ; Sequence Analysis, RNA
    Language English
    Publishing date 2024-03-08
    Publishing country United States
    Document type Journal Article
    ISSN 1945-4589
    ISSN (online) 1945-4589
    DOI 10.18632/aging.205628
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  2. Article ; Online: Elementary school teachers’ attitudes towards project-based learning in China

    Zhiling Cai / Jinxing Zhu / Yu Yu / Saiqi Tian

    Humanities & Social Sciences Communications, Vol 10, Iss 1, Pp 1-

    2023  Volume 11

    Abstract: Abstract This study analyzed the Chinese elementary school teachers’ attitudes toward project-based learning (PBL) and identified factors that may influence elementary school teachers’ attitudes. The analysis was based on a questionnaire survey of 257 ... ...

    Abstract Abstract This study analyzed the Chinese elementary school teachers’ attitudes toward project-based learning (PBL) and identified factors that may influence elementary school teachers’ attitudes. The analysis was based on a questionnaire survey of 257 elementary school teachers and interviews with 10 elementary school teachers in China. Results showed that Chinese elementary school teachers generally had positive attitudes towards PBL, but their attitudes differed based on their educational level, years of teaching, and subjects taught. Results of the regression analysis found that training, social support, resources, and availability of time all positively influenced teachers’ attitudes toward PBL. Finally, the interview data were analyzed to understand teachers’ perceptions of how they could be helped to use PBL in teaching.
    Keywords History of scholarship and learning. The humanities ; AZ20-999 ; Social Sciences ; H
    Language English
    Publishing date 2023-10-01T00:00:00Z
    Publisher Springer Nature
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  3. Article ; Online: NiFeP nanosheets for efficient and durable hydrazine-assisted electrolytic hydrogen production.

    Hou, Jinxing / Mei, Kaifeng / Jiang, Tongtong / Yu, Xinxin / Wu, Mingzai

    Dalton transactions (Cambridge, England : 2003)

    2024  Volume 53, Issue 10, Page(s) 4574–4579

    Abstract: Hydrazine-assisted electrochemical water splitting is an important avenue toward low cost and sustainable hydrogen production, which can significantly reduce the voltage of electrochemical water splitting. Herein, we took a simple approach to fabricate ... ...

    Abstract Hydrazine-assisted electrochemical water splitting is an important avenue toward low cost and sustainable hydrogen production, which can significantly reduce the voltage of electrochemical water splitting. Herein, we took a simple approach to fabricate NiFeP nanosheet arrays on nickel foam (NiFeP/NF), which exhibit superior electrocatalytic activity for the hydrogen evolution reaction (HER) and the hydrazine oxidation reaction (HzOR). Our investigations revealed that the excellent electrocatalytic activity of NiFeP/NF mainly arises from the bimetallic synergistic effect, abundant electrocatalytically active sites facilitated by the porous nanosheet morphology, high intrinsic conductivity of NiFeP/NF and strong NiFeP-NF adhesion. We assembled a hydrazine-boosted electrochemical water splitting cell using NiFeP/NF as a bifunctional catalyst for both electrodes, and the overall hydrazine splitting (OHzS) exhibits a considerably low overpotential (100 mV at 10 mA cm
    Language English
    Publishing date 2024-03-05
    Publishing country England
    Document type Journal Article
    ZDB-ID 1472887-4
    ISSN 1477-9234 ; 1364-5447 ; 0300-9246 ; 1477-9226
    ISSN (online) 1477-9234 ; 1364-5447
    ISSN 0300-9246 ; 1477-9226
    DOI 10.1039/d3dt04373h
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Article ; Online: Facile Synthesis of a Novel AgIO

    Shen, Liqiang / Ye, Tingting / Chen, Yehui / Chu, Bei / Chen, Hui / Hu, Jinxing / Yu, Yan

    Toxics

    2024  Volume 12, Issue 2

    Abstract: With the development of modern industry, the issue of water pollution has garnered increasing attention. Photocatalysis, as a novel green environmental technology that is resource-efficient, environmentally friendly, and highly promising, has found ... ...

    Abstract With the development of modern industry, the issue of water pollution has garnered increasing attention. Photocatalysis, as a novel green environmental technology that is resource-efficient, environmentally friendly, and highly promising, has found extensive applications in the field of organic pollutant treatment. However, common semiconductor materials exhibit either a relatively low photocatalytic efficiency in the visible light range or an inefficient separation of photogenerated charges, resulting in their limited ability to harness solar energy effectively. Consequently, the development of new photocatalysts has become a pivotal focus in current photocatalysis research to enhance solar energy utilization. This research provides a brief explanation of the photocatalytic mechanism of the AgIO
    Language English
    Publishing date 2024-02-06
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2733883-6
    ISSN 2305-6304 ; 2305-6304
    ISSN (online) 2305-6304
    ISSN 2305-6304
    DOI 10.3390/toxics12020133
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Article: The adverse role of endocrine disrupting chemicals in the reproductive system.

    Pan, Jing / Liu, Pengfei / Yu, Xiao / Zhang, Zhongming / Liu, Jinxing

    Frontiers in endocrinology

    2024  Volume 14, Page(s) 1324993

    Abstract: Reproductive system diseases pose prominent threats to human physical and mental well-being. Besides being influenced by genetic material regulation and changes in lifestyle, the occurrence of these diseases is closely connected to exposure to harmful ... ...

    Abstract Reproductive system diseases pose prominent threats to human physical and mental well-being. Besides being influenced by genetic material regulation and changes in lifestyle, the occurrence of these diseases is closely connected to exposure to harmful substances in the environment. Endocrine disrupting chemicals (EDCs), characterized by hormone-like effects, have a wide range of influences on the reproductive system. EDCs are ubiquitous in the natural environment and are present in a wide range of industrial and everyday products. Currently, thousands of chemicals have been reported to exhibit endocrine effects, and this number is likely to increase as the testing for potential EDCs has not been consistently required, and obtaining data has been limited, partly due to the long latency of many diseases. The ability to avoid exposure to EDCs, especially those of artificially synthesized origin, is increasingly challenging. While EDCs can be divided into persistent and non-persistent depending on their degree of degradation, due to the recent uptick in research studies in this area, we have chosen to focus on the research pertaining to the detrimental effects on reproductive health of exposure to several EDCs that are widely encountered in daily life over the past six years, specifically bisphenol A (BPA), phthalates (PAEs), polychlorinated biphenyls (PCBs), parabens, pesticides, heavy metals, and so on. By focusing on the impact of EDCs on the hypothalamic-pituitary-gonadal (HPG) axis, which leads to the occurrence and development of reproductive system diseases, this review aims to provide new insights into the molecular mechanisms of EDCs' damage to human health and to encourage further in-depth research to clarify the potentially harmful effects of EDC exposure through various other mechanisms. Ultimately, it offers a scientific basis to enhance EDCs risk management, an endeavor of significant scientific and societal importance for safeguarding reproductive health.
    MeSH term(s) Humans ; Endocrine Disruptors/toxicity ; Polychlorinated Biphenyls/toxicity ; Pesticides ; Genitalia
    Chemical Substances Endocrine Disruptors ; Polychlorinated Biphenyls (DFC2HB4I0K) ; Pesticides
    Language English
    Publishing date 2024-01-17
    Publishing country Switzerland
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 2592084-4
    ISSN 1664-2392
    ISSN 1664-2392
    DOI 10.3389/fendo.2023.1324993
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  6. Article ; Online: Enhanced performance of quantum dot light-emitting diodes enabled by zirconium doped SnO

    Zhao, Jinxing / Man, Zhongwei / Wang, Shuaibing / Hao, Chaoqi / Yu, Zhenzhen / Li, Xu / Tang, Aiwei

    Optics letters

    2024  Volume 49, Issue 8, Page(s) 1896–1899

    Abstract: Next-generation display and lighting based on quantum dot light-emitting diodes (QLEDs) require a balanced electron injection of electron transport layers (ETLs). However, classical ZnO nanoparticles (NPs) as ETLs face inherent defects such as excessive ... ...

    Abstract Next-generation display and lighting based on quantum dot light-emitting diodes (QLEDs) require a balanced electron injection of electron transport layers (ETLs). However, classical ZnO nanoparticles (NPs) as ETLs face inherent defects such as excessive electron injection and positive aging effects, urgently requiring the development of new types of ETL materials. Here, we show that high stability SnO
    Language English
    Publishing date 2024-04-15
    Publishing country United States
    Document type Journal Article
    ISSN 1539-4794
    ISSN (online) 1539-4794
    DOI 10.1364/OL.521324
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  7. Article ; Online: A

    Smith, Steven Christopher / Yu, Jinxing / Paul, Asit K

    International journal of surgical pathology

    2023  Volume 32, Issue 3, Page(s) 539–542

    Abstract: Recent years have seen the recognition and establishment of numerous subtypes of renal cell carcinoma (RCC), including adoption of an entire category of "molecularly defined renal carcinomas" in the fifth Edition of World Health Organization ... ...

    Abstract Recent years have seen the recognition and establishment of numerous subtypes of renal cell carcinoma (RCC), including adoption of an entire category of "molecularly defined renal carcinomas" in the fifth Edition of World Health Organization Classification. To add value, new diagnostic entities should be clinicopathologically distinct, or better, imply specific management and treatment angles, especially if adjunctive testing is needed for diagnosis. One such promising future treatment angle for a molecularly defined subtype,
    MeSH term(s) Humans ; Carcinoma, Renal Cell/diagnosis ; Carcinoma, Renal Cell/genetics ; Carcinoma, Renal Cell/therapy ; Retrospective Studies ; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors/genetics ; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors/metabolism ; Biomarkers, Tumor ; Kidney Neoplasms/diagnosis ; Kidney Neoplasms/genetics ; Kidney Neoplasms/therapy ; Immunotherapy
    Chemical Substances Basic Helix-Loop-Helix Leucine Zipper Transcription Factors ; Biomarkers, Tumor ; TFEB protein, human
    Language English
    Publishing date 2023-07-06
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 1336393-1
    ISSN 1940-2465 ; 1066-8969
    ISSN (online) 1940-2465
    ISSN 1066-8969
    DOI 10.1177/10668969231185077
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 4500: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  8. Article ; Online: Spontaneous periodic polarization wave in helielectric fluids.

    Zhou, Junchen / Zou, Yu / Li, Jinxing / Huang, Mingjun / Aya, Satoshi

    PNAS nexus

    2023  Volume 2, Issue 8, Page(s) pgad265

    Abstract: By analogy with spin waves in ferromagnetic systems, the polarization (or dipole) wave is the electric counterpart that remains elusive. Here, we discover that the helielectricity, i.e. a polarization field with helicoidal helices that corresponds to a ... ...

    Abstract By analogy with spin waves in ferromagnetic systems, the polarization (or dipole) wave is the electric counterpart that remains elusive. Here, we discover that the helielectricity, i.e. a polarization field with helicoidal helices that corresponds to a quasi-layered chiral nematic environment, causes a spontaneous formation of large-scale polarization waves in the form of the sinusoidal function. Both experimental and theoretical analyses reveal that the polarization ordering over a threshold polarization strength violates the inherent periodicity of the polarization helices, thus penalizing the compression energy. It drives a second-order structural transition to a periodically modulated polarization wave state. The roles of chirality and confinement condition are discussed.
    Language English
    Publishing date 2023-08-10
    Publishing country England
    Document type Journal Article
    ISSN 2752-6542
    ISSN (online) 2752-6542
    DOI 10.1093/pnasnexus/pgad265
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  9. Article ; Online: LaNbON2 mesoporous single crystals with expedited photocarrier separation for efficient visible-light-driven water redox reactions

    Yu, Jinxing / Xu, Xiaoxiang

    Journal of Catalysis. 2022 Sept., v. 413 p.858-869

    2022  

    Abstract: Combining structural coherence and large porosity, semiconducting porous single crystals (PSCs) warrant a great potential as photocatalysts. High photocarrier mobility can be realized in PSCs because of a deficiency in grain boundaries, which in turn ... ...

    Abstract Combining structural coherence and large porosity, semiconducting porous single crystals (PSCs) warrant a great potential as photocatalysts. High photocarrier mobility can be realized in PSCs because of a deficiency in grain boundaries, which in turn greatly alleviates photocarriers’ recombination. The large porosity of PSCs not only provides plenty of accessible surfaces to accommodate catalytic reaction sites but also fortifies photon-matter interplay by reflecting and scattering photons. In this work, taking LaNbON₂ PSCs as an example, we demonstrate the importance of PSCs in activating otherwise almost inactive photocatalyst. Compared to conventional inert LaNbON₂, LaNbON₂ PSCs exhibit exceptional activity for photocatalytic water redox reactions, delivering a high apparent quantum efficiency, i.e. 6.3% and 10.2% at 420 ± 20 nm for H₂- and O₂-evolution reactions, respectively. A Z-scheme system containing LaNbON₂ PSCs has succeeded in overall water splitting (H₂/O₂ molar ratio 2:1) with high stability under visible light illumination (λ ≥ 420 nm).
    Keywords light ; lighting ; photocatalysis ; photocatalysts ; porosity ; porous media ; semiconductors ; Water splitting ; LaNbON2 ; Mesoporous single crystal ; Solar energy conversion
    Language English
    Dates of publication 2022-09
    Size p. 858-869.
    Publishing place Elsevier Inc.
    Document type Article ; Online
    ZDB-ID 1468993-5
    ISSN 1090-2694 ; 0021-9517
    ISSN (online) 1090-2694
    ISSN 0021-9517
    DOI 10.1016/j.jcat.2022.07.033
    Database NAL-Catalogue (AGRICOLA)

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  10. Article: Integrated Metabolomic and Transcriptomic Analysis of the Flavonoid Accumulation in the Leaves of

    Du, Zhaokui / Lin, Weida / Yu, Binbin / Zhu, Jinxing / Li, Junmin

    Frontiers in plant science

    2022  Volume 12, Page(s) 794137

    Abstract: Cyclocarya ... ...

    Abstract Cyclocarya paliurus
    Language English
    Publishing date 2022-02-08
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2613694-6
    ISSN 1664-462X
    ISSN 1664-462X
    DOI 10.3389/fpls.2021.794137
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top