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  1. Article: Liposomes for paramagnetic contrast enhancement in n.m.r. imaging.

    Gore, J C / Sostman, H D / Caride, V J

    Journal of microencapsulation

    1986  Volume 3, Issue 4, Page(s) 251–264

    MeSH term(s) Animals ; Contrast Media/administration & dosage ; Drug Carriers ; Liposomes ; Magnetic Resonance Imaging/methods ; Mice
    Chemical Substances Contrast Media ; Drug Carriers ; Liposomes
    Language English
    Publishing date 1986-10
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 843632-0
    ISSN 1464-5246 ; 0265-2048
    ISSN (online) 1464-5246
    ISSN 0265-2048
    DOI 10.3109/02652048609021795
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: The Intersectionality of Climate Change and Post-Stroke Aphasia.

    Greenwald, Roby / Laures-Gore, Jacqueline S / Nogueira, Leticia M

    Seminars in speech and language

    2024  Volume 45, Issue 1, Page(s) 46–55

    Abstract: Persons with communication disabilities including persons with post-stroke aphasia (PWAs) possess a vulnerability to climate change as a result of their communication impairments. The disproportionate effects of climate change are likely to exacerbate ... ...

    Abstract Persons with communication disabilities including persons with post-stroke aphasia (PWAs) possess a vulnerability to climate change as a result of their communication impairments. The disproportionate effects of climate change are likely to exacerbate preexisting inequities in social determinants of health. Communication disability intersecting with other characteristics subject to discrimination (e.g., race, age, sex, income) may lead to inequities in climate-related adaptive capacity. This article echoes earlier concerns related to climate change and further educates healthcare professionals about the impact of climate change on the global human population, with particular consideration of PWAs. The aims of this article are the following: (1) to broaden the understanding of aphasiologists and clinicians caring for PWAs about climate change and the contributions of human activity (anthropogenic) to this crisis; (2) to describe climate change and its impact on health; (3) to detail the intersectionality of climate and health; (4) to explore climate change and its potential effects on PWAs; and (5) to offer hope through emissions reduction, adaptation, resilience, and immediate change.
    MeSH term(s) Humans ; Climate Change ; Intersectional Framework ; Aphasia/etiology ; Resilience, Psychological
    Language English
    Publishing date 2024-01-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 604960-6
    ISSN 1098-9056 ; 0734-0478
    ISSN (online) 1098-9056
    ISSN 0734-0478
    DOI 10.1055/s-0043-1777858
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: The biology and ecology of the basking shark: A review.

    Gore, Mauvis / Camplisson, Ewan / Ormond, Rupert

    Advances in marine biology

    2023  Volume 95, Page(s) 113–257

    Abstract: Here we review the literature on the basking shark (Cetorhinus maximus, Gunnerus, 1765), well known as the second largest extant shark (and fish) species globally. Previous reviews were published by Kunzlik in 1988 and Sims in 2008, but in the last 15 ... ...

    Abstract Here we review the literature on the basking shark (Cetorhinus maximus, Gunnerus, 1765), well known as the second largest extant shark (and fish) species globally. Previous reviews were published by Kunzlik in 1988 and Sims in 2008, but in the last 15 years modern electronic and DNA sequencing technologies have resulted in considerable advances in our knowledge of the species' behaviour and ecology. Basking sharks are planktivores and under appropriate conditions spend prolonged periods at the ocean surface feeding on copepod prey that primarily make up their diet, the behaviour that gave rise to their common name. In general, they are migratory and move into higher latitude waters during the summer months, when loose surface-feeding aggregations may form at favoured sites, the best known of which at present occur at hotspots on the west coasts of Britain and Ireland. The species is found circumglobally in temperate waters, but they are also now known on occasion to migrate at depth between northern and southern hemispheres, as well as across oceans within the northern hemisphere. In the past basking shark were more abundant across much of their range, but, consequent on targeted fisheries and in some places intentional eradication, became everywhere scarce, with recent population recovery in the north-east Atlantic being the result of protective measures initiated in the 1990s. Despite their charismatic nature, some of their most fundamental biological processes including copulation, gestation and birth remain largely unknown, due to their migratory and often deep-water lifestyle. In contrast, the deployment of small-scale archival and satellite tags has revealed the details of both broadscale migratory movements and horizontal and vertical foraging behaviours. Recent genetic studies support evidence suggesting a degree of site fidelity in relation to seasonal feeding grounds, which likely explains why in the past local populations have collapsed following periods of intensive fishing. Other recent research using aerial drones and towed cameras has revealed within loose feeding aggregations elements of social behaviour that may have a courtship function as well as enhance feeding efficiency.
    MeSH term(s) Animals ; Ecology ; Oceans and Seas ; Animal Migration ; Sharks ; Diet
    Language English
    Publishing date 2023-10-28
    Publishing country United States
    Document type Review ; Journal Article
    ISSN 2162-5875
    ISSN (online) 2162-5875
    DOI 10.1016/bs.amb.2023.08.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Perspectives on developing moral courage in pre-licensure education: A qualitative study.

    Wawersik, Dawn M / Boutin, Emile R / Gore, Teresa / Palaganas, Janice C

    Nurse education in practice

    2023  Volume 70, Page(s) 103646

    Abstract: Background: Error reporting and speaking up are mechanisms to reduce the incidence of healthcare errors. However, organizational policies don't always align with individuals' perceptions and beliefs to promote these mechanisms. When this misalignment ... ...

    Abstract Background: Error reporting and speaking up are mechanisms to reduce the incidence of healthcare errors. However, organizational policies don't always align with individuals' perceptions and beliefs to promote these mechanisms. When this misalignment produces fear, moral courage, which is taking action regardless of personal consequences, becomes necessary. Teaching moral courage in pre-licensure education may set a foundation for individuals to speak up in post-licensure careers.
    Aim: To explore health professionals' perceptions of healthcare reporting and organizational culture to inform pre-licensure education on how to promote moral courage.
    Methods: Thematic analysis of four semi-structured focus groups with fourteen health professions educators followed by in-depth, semi-structured individual interviews.
    Findings: Organizational factors, characteristics that an individual must possess to enact moral courage and priority methods to guide moral courage were identified.
    Conclusions: This study outlines the need for leadership education in moral courage and offers educational interventions to promote reporting and aid in developing moral courage academic guidelines to improve healthcare error reporting and speaking up behaviors.
    MeSH term(s) Humans ; Courage ; Ethics, Nursing ; Educational Status ; Organizational Culture ; Morals
    Language English
    Publishing date 2023-04-25
    Publishing country Scotland
    Document type Journal Article
    ZDB-ID 2058575-5
    ISSN 1873-5223 ; 1471-5953
    ISSN (online) 1873-5223
    ISSN 1471-5953
    DOI 10.1016/j.nepr.2023.103646
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Individual Characteristics That Promote or Prevent Psychological Safety and Error Reporting in Healthcare: A Systematic Review.

    Wawersik, Dawn M / Boutin, Emile R / Gore, Teresa / Palaganas, Janice C

    Journal of healthcare leadership

    2023  Volume 15, Page(s) 59–70

    Abstract: Background: Healthcare errors continue to be a safety issue and an economic burden that causes death, increased length of stays, and emotional trauma to families and the person who commits the error.  Speaking up and error reporting within a safety ... ...

    Abstract Background: Healthcare errors continue to be a safety issue and an economic burden that causes death, increased length of stays, and emotional trauma to families and the person who commits the error.  Speaking up and error reporting within a safety culture can reduce the incidence of error; however, this is complex and multifaceted.
    Aim: This systematic review investigates individual characteristics that support or prevent speaking up behaviors when adverse events occur.  This study further explores how organizational interventions designed to promote error reporting correlate to individual characteristics and perceptions of psychological safety.  .
    Methods: A systematic review of peer-reviewed articles in healthcare that contain characteristics of an individual that promote or prevent error reporting was conducted. The search yielded 1233 articles published from 2015 to 2021. From this set, 81 full-text articles were assessed for eligibility and ultimately extracted data from 28 articles evaluated for quality using Joanna Briggs Institute critical appraisal tools©.
    Principal findings: The primary themes for individual character traits, values, and beliefs that influence a person's decision to speak up/report an error include self-confidence and positive perceptions of self, the organization, and leadership. Education, experience and knowledge are sub themes that relate to confidence. The primary individual characteristics that serve as barriers are 1) self-preservation associated with fear and 2) negative perceptions of self, the organization, and leadership.
    Conclusion: The results show that an individual's perception of their environment, whether or not it is psychologically safe, may be impacted by personal perceptions that stem from deep-seated personal values. This exposes a crucial need to explore cultural and diversity aspects of healthcare error reporting and how to individualize interventions to reduce fear and promote error reporting.
    Language English
    Publishing date 2023-04-17
    Publishing country New Zealand
    Document type Journal Article ; Review
    ZDB-ID 2587466-4
    ISSN 1179-3201 ; 1179-3201
    ISSN (online) 1179-3201
    ISSN 1179-3201
    DOI 10.2147/JHL.S369242
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: The Intersectionality of Climate Change and Post-Stroke Aphasia

    Greenwald, Roby / Laures-Gore, Jacqueline S. / Nogueira, Leticia M.

    Seminars in Speech and Language

    (Intersectionality in Aphasia Services for Ethnosocially Diverse Adult Populations)

    2024  Volume 45, Issue 01, Page(s) 46–55

    Abstract: Persons with communication disabilities including persons with post-stroke aphasia (PWAs) possess a vulnerability to climate change as a result of their communication impairments. The disproportionate effects of climate change are likely to exacerbate ... ...

    Series title Intersectionality in Aphasia Services for Ethnosocially Diverse Adult Populations
    Abstract Persons with communication disabilities including persons with post-stroke aphasia (PWAs) possess a vulnerability to climate change as a result of their communication impairments. The disproportionate effects of climate change are likely to exacerbate preexisting inequities in social determinants of health. Communication disability intersecting with other characteristics subject to discrimination (e.g., race, age, sex, income) may lead to inequities in climate-related adaptive capacity. This article echoes earlier concerns related to climate change and further educates healthcare professionals about the impact of climate change on the global human population, with particular consideration of PWAs. The aims of this article are the following: (1) to broaden the understanding of aphasiologists and clinicians caring for PWAs about climate change and the contributions of human activity (anthropogenic) to this crisis; (2) to describe climate change and its impact on health; (3) to detail the intersectionality of climate and health; (4) to explore climate change and its potential effects on PWAs; and (5) to offer hope through emissions reduction, adaptation, resilience, and immediate change.
    Keywords aphasia ; climate change ; disability ; climate justice
    Language English
    Publishing date 2024-01-01
    Publisher Thieme Medical Publishers, Inc.
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 604960-6
    ISSN 1098-9056 ; 0734-0478
    ISSN (online) 1098-9056
    ISSN 0734-0478
    DOI 10.1055/s-0043-1777858
    Database Thieme publisher's database

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  7. Article ; Online: Prediction of behavioral MCL using electrophysiological responses in children using MED-EL implant.

    Thangaraj, Muthuselvi / Arunachalam, Ravikumar / Gore, Madhuri / AjithKumar, Uppunda

    International journal of pediatric otorhinolaryngology

    2023  Volume 172, Page(s) 111696

    Abstract: The present study aimed to correlate the various electrophysiological tests of ECAP, EABR and ESRT with programming parameters. If there is a correlation between them, fitting formulae to be derived to predict programming parameters. Further this fitting ...

    Abstract The present study aimed to correlate the various electrophysiological tests of ECAP, EABR and ESRT with programming parameters. If there is a correlation between them, fitting formulae to be derived to predict programming parameters. Further this fitting formula was validated on a clinical population. 22 children between age range of 5-12 years using MED-EL implant participated study. Electrophysiological tests of Electrically evoked compound Action Potential (ECAP), Electrical Evoked Stapedial Reflex Threshold (ESRT) and Electrically Evoked Auditory Brain Stem Responses (EABR) were measured on electrodes no 1,4, 8, and 11. Based on Pearson correlation analysis, there was a moderate correlation observed between each of electrophysiological tests with MCL level. Fitting formulae of ECAP with either ESRT or EABR were found to be accurately predict the MCL level. These fitting formulae were clinically validated on 6 children using Sonata implant with OPUS 2 processor. Two new programs with MCL were predicted using combination of ECAP with EABR and ECAP with ESRT as parameters in the fitting formulae. These programs were given to the participants to use for two weeks. Predicted MCLs were found to slightly higher (about 2qu to 5qu) than original MCL level. Reliability analysis indicated that the formulae predicted MCL with good accuracy. Speech perception and sound field thresholds were measured in the participants' Everyday program and two predicted programs. When ECAP & EABR were the parameters, the predicted program had improved audibility as reflected in sound field thresholds as compared to those obtained with other two programs. Based on Freidman test, the results indicated that significantly lower thresholds were found for both ECAP & EABR, or ECAP & ESRT based programs when compared to Everyday program. However, speech perception scores were not significantly different among the program as per Freidman test. Thus, both the fitting models were clinically validated. The findings imply that it is not always advisable to run all three electrophysiological testing to predict the MCL levels in clinical population. It would save lot of time to run just two tests to predict the MCL in difficult to test population.
    MeSH term(s) Adult ; Child ; Humans ; Child, Preschool ; Cochlear Implants ; Reproducibility of Results ; Auditory Threshold/physiology ; Evoked Potentials, Auditory, Brain Stem/physiology ; Cochlear Implantation/methods ; Evoked Potentials, Auditory/physiology ; Electric Stimulation
    Language English
    Publishing date 2023-08-06
    Publishing country Ireland
    Document type Journal Article
    ZDB-ID 754501-0
    ISSN 1872-8464 ; 0165-5876
    ISSN (online) 1872-8464
    ISSN 0165-5876
    DOI 10.1016/j.ijporl.2023.111696
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Coaching Home Care Clients to Prepare Their Homes for Safe Care Visits: A Mixed-Methods Study to Evaluate a Nurse-Led Educational Intervention Process.

    Markkanen, Pia K / Gore, Rebecca J / Sama, Susan R / Lindberg, John E / Galligan, Catherine J / Quinn, Margaret M

    International journal of environmental research and public health

    2024  Volume 21, Issue 3

    Abstract: Assuring home care (HC) workers' safety is challenging because the work environment is a private home. This paper presents the process evaluation for a proof-of-concept safety intervention study to assess whether nurse-led safety coaching, using ... ...

    Abstract Assuring home care (HC) workers' safety is challenging because the work environment is a private home. This paper presents the process evaluation for a proof-of-concept safety intervention study to assess whether nurse-led safety coaching, using motivational interviewing and a safety handbook, could enable HC clients to improve safety in their homes. The process evaluation objectives were to (i) document the intervention's implementation progress and (ii) assess the intervention's dose delivery, dose reception, and fidelity. Five agencies employing liaisons (
    MeSH term(s) Humans ; Mentoring ; Nurse's Role ; Home Care Services
    Language English
    Publishing date 2024-03-18
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2175195-X
    ISSN 1660-4601 ; 1661-7827
    ISSN (online) 1660-4601
    ISSN 1661-7827
    DOI 10.3390/ijerph21030360
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Epithelial-myoepithelial carcinoma: a population-based survival analysis.

    Gore, Mitchell R

    BMC ear, nose, and throat disorders

    2018  Volume 18, Page(s) 15

    Abstract: ... for patient T (tumor), N (nodal), and M (metastasis) stage, tumor site, and demographic characteristics ... with submandibular gland representing 9.8% of patients. Distant metastasis (M) status was unknown in 33.3%, with 2.6% being ... significantly affected survival. On multivariate analysis age, race, AJCC stage, T, N, M stage, and treatment ...

    Abstract Background: Epithelial-myoepithelial carcinoma is an uncommon malignant neoplasm seen most frequently in the salivary glands, representing approximately 1 to 2% of salivary gland tumors. Less than 600 cases have been reported in the literature since its initial description in 1972. The aim of this study was to examine demographic, site, stage, and survival factors in patients with epithelial-myoepithelial carcinoma.
    Methods: The 1973-2014 SEER (Surveillance, Epidemiology, and End Results) cancer database was queried for patients treated for epithelial-myoepithelial carcinoma. The data was analyzed for patient T (tumor), N (nodal), and M (metastasis) stage, tumor site, and demographic characteristics. The Kaplan-Meier model was used to estimate actuarial survival.
    Results: A total of 468 patients were identified. White patients represented 78.0% of the total. There were 291 female patients and 177 male patients. Overall 5-, 10-, and 20-year survival was 72.7%, 59.5%, and 38.3%, respectively. Mean survival time was 165.5 months. Parotid gland was the most common site with 57.7% of patients, with submandibular gland representing 9.8% of patients. Distant metastasis (M) status was unknown in 33.3%, with 2.6% being M1, 3.0% being MX, and 61.1% M0. Nodal metastasis (N) status was unknown in 33.3%, while 4.4% were N+, 4.7% were NX, and 57.5% were N0. 88.2% of patients had surgery as part or all of the treatment regimen. Univariate Kaplan-Meier analysis showed that AJCC overall stage, primary tumor (T) stage, nodal (N) stage, presence of distant metastasis (M1), age at diagnosis, race, and non-surgical treatment significantly affected survival. On multivariate analysis age, race, AJCC stage, T, N, M stage, and treatment type were significant.
    Conclusions: Epithelial-myoepithelial carcinoma is a malignant, histologically biphasic neoplasm most frequently seen in the parotid gland. The nodal and distant metastasis rates are low. Age at diagnosis, race, AJCC stage, T, N, M stage, and treatment type all significantly affected survival.
    Language English
    Publishing date 2018-08-16
    Publishing country England
    Document type Journal Article
    ZDB-ID 2091302-3
    ISSN 1472-6815
    ISSN 1472-6815
    DOI 10.1186/s12901-018-0063-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Survival in sinonasal and middle ear malignancies: a population-based study using the SEER 1973-2015 database.

    Gore, Mitchell R

    BMC ear, nose, and throat disorders

    2018  Volume 18, Page(s) 13

    Abstract: ... On univariate analysis surgical vs. nonsurgical treatment, sex, race, age at diagnosis, T stage, N stage, M ... nonsurgical treatment, and T, N, and M stage remained significant predictors of overall survival ... relatively low. Higher T, N, M, and overall stage and higher tumor grade is associated with lower survival ...

    Abstract Background: The sinuses, nasal cavity, and middle ear represent a rarer location of head and neck malignancy than more common sites such as the larynx and oral cavity. Population-based studies are a useful tool to study the demographic and treatment factors affecting survival in these malignancies.
    Methods: Population-based database search of the Survival, Epidemiology, and End Results (SEER) database from 1973 to 2015 for malignancies involving the nasal cavity, paranasal sinuses, and middle ear. Data were analyzed for demographics, treatment type, stage, primary site and histopathologic type. Kaplan-Meier analysis was used to assess and compare survival.
    Results: A total of 13,992 cases of sinonasal or middle ear malignancy were identified and analyzed. The majority of patients were between ages 50 and 80 at the time of diagnosis. Overall 5-, 10-, and 20-year survival was 45.7%, 32.2%, and 16.4%, respectively. Lymph node metastasis was reported in 4.4% of patients, while distant metastasis was present in 1.5% of cases. On univariate analysis surgical vs. nonsurgical treatment, sex, race, age at diagnosis, T stage, N stage, M stage, AJCC overall stage, primary site, tumor grade, and histopathologic subtype significantly affected survival. On multivariate analysis age, race, sex, primary site, overall AJCC stage, surgical vs. nonsurgical treatment, and T, N, and M stage remained significant predictors of overall survival.
    Conclusions: Malignancies of the nasal cavity, paranasal sinuses, and middle ear account for a minority of overall head and neck cancers. The overall 5-, 10-, and 20-year survival for these malignancies is relatively low. Higher T, N, M, and overall stage and higher tumor grade is associated with lower survival. Patients treated with surgery as part of the treatment regimen had higher overall survival. Demographics and primary site also significantly affect survival. Certain histopathologic subtypes were associated with poorer survival.
    Language English
    Publishing date 2018-08-09
    Publishing country England
    Document type Journal Article
    ZDB-ID 2091302-3
    ISSN 1472-6815
    ISSN 1472-6815
    DOI 10.1186/s12901-018-0061-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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