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Article ; Online: Landers M, Creger R, Baker C, Stutelberg K. The use of fear-avoidance beliefs and non-organic signs in predicting prolonged disability in patients with neck pain. Manual Therapy 2007; doi:10.1016/j.math.2007.01.010.

Sterling, Michele / Williamson, Owen D

2008 Volume 13, Issue 3, Page(s) e1–2; author reply e3–4

MeSH term(s)	Disability Evaluation ; Disabled Persons/psychology ; Fear/psychology ; Humans ; Neck Pain/classification ; Neck Pain/psychology
Language	English
Publishing date	2008-06
Publishing country	Scotland
Document type	Comment ; Letter
ZDB-ID	2010590-3
ISSN	1532-2769 ; 1356-689X
ISSN (online)	1532-2769
ISSN	1356-689X
DOI	10.1016/j.math.2007.10.004
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Article ; Conference proceedings ; Online: RESULTS OF A DISCUSSION ABOUT TECHNICAL PROBLEMS IN TAXONOMIC RESEARCH ON FLAVOBACTERIA AND CYTOPHAGA-LIKE BACTERIA

Owen, R. J.

2023

Abstract: The participants of the symposium felt, that an exchange of results and ideas between the two groups of investigators working with flavobacteria on the one side, and with Cytophaga-like bacteria on the other, could potentially be very useful and ... ...

Abstract	The participants of the symposium felt, that an exchange of results and ideas between the two groups of investigators working with flavobacteria on the one side, and with Cytophaga-like bacteria on the other, could potentially be very useful and stimulating for both sides, particularly as the borders between some of these bacteria tend to vanish. Closer contacts within each group of microbiologists, and between the two,would be highly desirable. To promote such contacts it was proposed, a) to start a Newsletter on Flavobacteria and Cytophaga-Like Bacteria, and b) to repeat meetings of the kind just concluded from time to time. Dr. 0.B. Weeks from Las Cruces, New Mexico, kindly took over responsibility for compiling and distributing the Newsletter
Language	English
Publishing date	2023-03-29
Publisher	GBF - Gesellschaft für Biotechnologische Forschung
Publishing country	de
Document type	Article ; Conference proceedings ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Adolescent Perceptions of Adult-Mediated Healthcare Communication.

Owen, Aleksa / Owen, Randall / Batz, Ruby / Marasco-Wetzel, Jade

Social work in public health

2024 Volume 38, Issue 5-8, Page(s) 400–415

Abstract: Adolescence is a time of rapid growth and development and may be accompanied by increased risk-taking behaviors and independence. Youth are particularly at risk for high levels of stress, decreased physical activity, unsafe sexual activity, abuse, ... ...

Abstract	Adolescence is a time of rapid growth and development and may be accompanied by increased risk-taking behaviors and independence. Youth are particularly at risk for high levels of stress, decreased physical activity, unsafe sexual activity, abuse, depression, and suicide. Considering the unique health risks adolescents face, healthcare service access and utilization can play a pivotal role in promoting positive long term health outcomes throughout adulthood. At the same time, adolescents must often rely on parents/caregivers to mediate their healthcare access. Understanding how adolescents perceive adult interactions within healthcare is important for developing interventions that increase youth access to healthcare. We found that adolescents perceived adult-mediated healthcare experiences as either supportive (Subthemes: Recognition Builds Trust and Validation) or unsupportive (Subthemes: Adult-Focused Communication and Lack of Privacy). Based on our findings, we argue that prevention-focused interventions should include communication-based strategies. We discuss social work and healthcare practice and policy implications of these findings.
MeSH term(s)	Adult ; Humans ; Adolescent ; Qualitative Research ; Sexual Behavior ; Health Services Accessibility ; Communication ; Caregivers
Language	English
Publishing date	2024-02-06
Publishing country	United States
Document type	Journal Article
ZDB-ID	2414992-5
ISSN	1937-190X ; 1937-1918
ISSN (online)	1937-190X
ISSN	1937-1918
DOI	10.1080/19371918.2024.2314022
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Book ; Online: Accumulation rates of sediments and main sedimentary components in ODP Leg 121 holes on Broken Ridge, supplementary data to: Rea, David K; Dehn, Jonathan; Driscoll, Neal W; Farrell, John W; Janecek, Thomas R; Owen, Robert M; Pospichal, James J; Resiwati, Purtyasti (1990): Paleoceanography of the eastern Indian Ocean from ODP Leg 121 drilling on Broken Ridge. Geological Society of America Bulletin, 102(5), 679-690

Rea, David K / Dehn, Jonathan / Driscoll, Neal W / Farrell, John W / Janecek, Thomas R / Owen, Robert M / Pospichal, James J / Resiwati, Purtyasti

1990

Abstract: Broken Ridge, in the eastern Indian Ocean,is overlain by about 1600 m of middle Cretaceous to Pleistocene tuffaceous and carbonate sediments that record the oceanographic history of southern hemisphere mid-to high-latitude regions. Prior to about 42 Ma, ... ...

Abstract	Broken Ridge, in the eastern Indian Ocean,is overlain by about 1600 m of middle Cretaceous to Pleistocene tuffaceous and carbonate sediments that record the oceanographic history of southern hemisphere mid-to high-latitude regions. Prior to about 42 Ma, Broken Ridge formed the northern part of the broad Kerguelen-Broken Ridge Plateau. During the middle Eocene, this feature was split by the newly forming Southeast Indian Ocean Ridge; since then, Broken Ridge has drifted north from about 55° to 31°S. The lower part of the sedimentary section is characterized by Turonian to Santonian tuffs that contain abundant glauconite and some carbonate. The tuffs record a large but apparently local volcanic input that characterized the central part of Broken Ridge into the early Tertiary. Maestrichtian shallow-water(several hundred to 1000 m depth) limestones and cherts accumulated at some of the highest rates ever documented from the open ocean, 4 to 5 g/cm**2/kyr. A complete (with all biostratigraphic zones) Cretaceous-Tertiary boundary section was recovered from site 752. The first 1.5 m.y. of the Tertiary is characterized by an order-of-magnitude reduction in the flux of biogenic sediments, indicating a period of sharply reduced biological productivity at 55°S, following which the carbonate and silica sedimentation rates almost reach the previous high values of the latest Cretaceous. We recovered a complete section through the Paleocene that contains all major fossil groups and is more than 300 m thick, perhaps the best pelagic Paleocene section encountered in ocean drilling. About 42 Ma, Broken Ridge was uplifted 2500 m in response to the intra-plateau rifting event; subsequent erosion and deposition has resulted in a prominent Eocene angular unconformity atop the ridge. An Oligocene disconformity characterized by a widespread pebble layer probably represents the 30 Ma sea-level fall. The Neogene pelagic ooze on Broken Ridge has been winnowed, and thus its grain size provides a direct physical record of the energy of the southern hemisphere drift current in the Indian Ocean for the past 30 m.y.
Language	English
Dates of publication	1990-9999
Size	Online-Ressource
Publisher	PANGAEA - Data Publisher for Earth & Environmental Science
Publishing place	Bremen/Bremerhaven
Document type	Book ; Online
Note	This dataset is supplement to doi:10.1130/0016-7606(1990)102<0679:POTEIO>2.3.CO;2
DOI	10.1594/PANGAEA.720962
Database	Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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Article ; Online: Shrinkage priors for isotonic probability vectors and binary data modeling, with applications to dose-response modeling.

Boonstra, Philip S / Owen, Daniel R / Kang, Jian

Pharmaceutical statistics

2024

Abstract: ... Our methodology is implemented in the R package isotonicBayes and therefore suitable for use in the design of dose ...

Abstract	Motivated by the need to model dose-response or dose-toxicity curves in clinical trials, we develop a new horseshoe-based prior for Bayesian isotonic regression modeling a binary outcome against an ordered categorical predictor, where the probability of the outcome is assumed to be monotonically non-decreasing with the predictor. The set of differences between outcome probabilities in consecutive categories of the predictor is equipped with a multivariate prior having support over simplex. The Dirichlet distribution, which can be derived from a normalized sum of independent gamma-distributed random variables, is a natural choice of prior, but using mathematical and simulation-based arguments, we show that the resulting posterior is prone to underflow and other numerical instabilities, even under simple data configurations. We propose an alternative prior based on horseshoe-type shrinkage that is numerically more stable. We show that this horseshoe-based prior is not subject to the numerical instability seen in the Dirichlet/gamma-based prior and that the horseshoe-based posterior can estimate the underlying true curve more efficiently than the Dirichlet-based one. We demonstrate the use of this prior in a model predicting the occurrence of radiation-induced lung toxicity in lung cancer patients as a function of dose delivered to normal lung tissue. Our methodology is implemented in the R package isotonicBayes and therefore suitable for use in the design of dose-finding studies or other dose-response modeling contexts.
Language	English
Publishing date	2024-02-23
Publishing country	England
Document type	Journal Article
ZDB-ID	2083706-9
ISSN	1539-1612 ; 1539-1604
ISSN (online)	1539-1612
ISSN	1539-1604
DOI	10.1002/pst.2372
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Article ; Conference proceedings ; Online: IDENTIFICATION AND CLASSIFICATION OF FLAVOBACTERIUM SPECIES FROM CLINICAL SOURCES

Owen, R. J. / Holmes, B.

2023

Abstract: Clinical isolates of aerobic yellow-pigmented, Gram-negative bacteria allied to Flavobacterium are classified in five taxa of which F. meningosepticum, F. odoratum and Group IIb are of some importance as human pathogens. Antibiotic resistance is a ... ...

Abstract	Clinical isolates of aerobic yellow-pigmented, Gram-negative bacteria allied to Flavobacterium are classified in five taxa of which F. meningosepticum, F. odoratum and Group IIb are of some importance as human pathogens. Antibiotic resistance is a feature of these bacteria and preliminary data suggest their resistance is chromo— somally determined and not plasmid mediated. The taxa can be separated from each other by various biochemical tests and by data on chromosomal DNA characteristics. The similarities within and between species of Flavobacterium can be conveniently illustrated by means of bivariate scatter diagrams, with GiC content and base pairing as the variables. It is evident from such diagrams that most clinical species of Flavobacterium and unnamed taxa are comprised of a 'core' of highly related strains (typical strains) with a number of 'outliers' (atypical strains). The classification of the latter strains is problematic since they are often indistinguishable from typical strains in conventional phenotypic tests. The food and environmental strains so far examined are often atypical when compared with the clinical isolates.
Subject code	610
Language	English
Publishing date	2023-03-29
Publisher	GBF - Gesellschaft für Biotechnologische Forschung
Publishing country	de
Document type	Article ; Conference proceedings ; Online
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Book ; Conference proceedings ; Online: Geochemistry of ODP Hole 121-752A, supplementary data to: Owen, Robert M; Zimmerman, Andrew R (1991): Geochemistry of Broken Ridge sediments. In: Weissel, J; Peirce, J; Taylor, E; et al. (eds.), Proceedings of the Ocean Drilling Program, Scientific Results, College Station, TX (Ocean Drilling Program), 121, 437-445

Owen, Robert M / Zimmerman, Andrew R

1991

Abstract: The present study involves the analysis and interpretation of geochemical data from a suite of sediment samples recovered at ODP Hole 752A. The samples encompass the time period that includes the lithospheric extension and uplift of Broken Ridge, and ... ...

Abstract	The present study involves the analysis and interpretation of geochemical data from a suite of sediment samples recovered at ODP Hole 752A. The samples encompass the time period that includes the lithospheric extension and uplift of Broken Ridge, and they record deposition below and above the mid-Eocene angular unconformity that denotes this uplift. A Q-mode factor analysis of the geochemical data indicates that the sediments in this section are composed of a mixture of three geochemical end members that collectively account for 94.2% of the total variance in the data. An examination of interelement ratios for each of these end members suggests that they represent the following sedimentary components: (1) a biogenic component, (2) a volcanogenic component, and (3) a hydrothermal component. The flux of the biogenic component decreases almost thirtyfold across the Eocene unconformity. This drastic reduction in the deposition of biogenic materials corresponds to the almost complete disappearance of chert layers, diatoms, and siliceous microfossils and is coincident with the uplift of Broken Ridge. The volcanogenic component is similar in composition to Santonian ash recovered at Hole 755A on Broken Ridge and is the apparent source of the Fe-stained sediment that immediately overlies the angular unconformity. This finding suggests that significant amounts of Santonian ash were subaerially exposed, weathered, and redeposited and is consistent with data that suggest that the vertical uplift of Broken Ridge was both rapid and extensive. The greatest flux of hydrothermal materials is recorded in the sediments immediately below the angular unconformity. This implies that the uplift of Broken Ridge was preceded by a significant amount of rifting, during which faulting and fracturing of the lithosphere led to enhanced hydrothermal circulation. This time sequence of events is consistent with (but not necessarily diagnostic of) the passive model of lithospheric extension and uplift.
Language	English
Dates of publication	1991-9999
Size	Online-Ressource
Publisher	PANGAEA - Data Publisher for Earth & Environmental Science
Publishing place	Bremen/Bremerhaven
Document type	Book ; Conference proceedings ; Online
Note	This dataset is supplement to doi:10.2973/odp.proc.sr.121.131.1991
DOI	10.1594/PANGAEA.759123
Database	Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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Book ; Conference proceedings ; Online: Major and trace element concentrations, accumulation rates and carbonate content in ODP Hole 121-752B (Table 1), supplementary data to: Owen, Robert M; Zimmerman, Andrew R (1991): Geochemistry of the Cretaceous/Tertiary boundary at Hole 752B, Broken Ridge. In: Weissel, J; Peirce, J; Taylor, E; et al. (eds.), Proceedings of the Ocean Drilling Program, Scientific Results, College Station, TX (Ocean Drilling Program), 121, 423-433

Owen, Robert M / Zimmerman, Andrew R

1991

Abstract: Statistical analyses of sediment geochemical data from a Cretaceous/Tertiary (KT) boundary section at Broken Ridge indicate that the sediments here are composed of three major geochemical end-members: (1) a biogenic/dissolution residue component; (2) a ... ...

Abstract	Statistical analyses of sediment geochemical data from a Cretaceous/Tertiary (KT) boundary section at Broken Ridge indicate that the sediments here are composed of three major geochemical end-members: (1) a biogenic/dissolution residue component; (2) a volcanogenic component; and (3) a diagenetic/alteration product component. The KT boundary at Broken Ridge is overlain by a 6-m-thick ash-rich layer. Relative flux comparisons of the three geochemical end-members suggest, however, this layer is the result of a dramatic (11-fold) decrease in biological productivity immediately following the KT boundary event, while both the flux and composition of the volcanogenic component remain constant across the KT boundary. The volcanogenic component apparently is derived from a local source, and we find no evidence of a causal link between volcanic activity and the KT boundary event. The flux of the diagenetic component, which is enriched in Au, increases sharply at the KT boundary. All other elements associated with this component are present in significant amounts in the other two geochemical end-members. With the possible exception of Au, then, geochemical anomalies in the sediments just below the KT boundary appear to result from diagenetic alteration of biogenic and volcanogenic sediment precursors.
Language	English
Dates of publication	1991-9999
Size	Online-Ressource
Publisher	PANGAEA - Data Publisher for Earth & Environmental Science
Publishing place	Bremen/Bremerhaven
Document type	Book ; Conference proceedings ; Online
Note	This dataset is supplement to doi:10.2973/odp.proc.sr.121.147.1991
DOI	10.1594/PANGAEA.759118
Database	Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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Article: Autism: A model of neurodevelopmental diversity informed by genomics.

Chawner, Samuel J R A / Owen, Michael J

Frontiers in psychiatry

2022 Volume 13, Page(s) 981691

Abstract: Definitions of autism are constantly in flux and the validity and utility of diagnostic criteria remain hotly debated. The boundaries of autism are unclear and there is considerable heterogeneity within autistic individuals. Autistic individuals ... ...

Abstract	Definitions of autism are constantly in flux and the validity and utility of diagnostic criteria remain hotly debated. The boundaries of autism are unclear and there is considerable heterogeneity within autistic individuals. Autistic individuals experience a range of co-occurring conditions notably including other childhood onset neurodevelopmental conditions such as intellectual disability, epilepsy and ADHD, but also other neuropsychiatric conditions. Recently, the neurodiversity movement has challenged the conception of autism as a medical syndrome defined by functional deficits. Whereas others have argued that autistic individuals with the highest support needs, including those with intellectual disability and limited functional communication, are better represented by a medical model. Genomic research indicates that, rather than being a circumscribed biological entity, autism can be understood in relation to two continua. On the one hand, it can be conceived as lying on a continuum of population variation in social and adaptive functioning traits, reflecting in large part the combination of multiple alleles of small effect. On the other, it can be viewed as lying on a broader neurodevelopmental continuum whereby rare genetic mutations and environmental risk factors impact the developing brain, resulting in a diverse spectrum of outcomes including childhood-onset neurodevelopmental conditions as well as adult-onset psychiatric conditions such as schizophrenia. This model helps us understand heterogeneity within autism and to reconcile the view that autism is a part of natural variability, as advocated by the neurodiversity movement, with the presence of co-occurring disabilities and impairments of function in some autistic individuals.
Language	English
Publishing date	2022-09-02
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2564218-2
ISSN	1664-0640
ISSN	1664-0640
DOI	10.3389/fpsyt.2022.981691
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Low-Field Magnetic Resonance Imaging Findings of the Fetlock Region of Nonracehorses.

Auth, Adel K / Hinnigan, Guy J / Smith, Meredith A / Owen, Kathryn R

Journal of equine veterinary science

2023 Volume 132, Page(s) 104938

Abstract: Low-field, magnetic resonance imaging (MRI) is an advanced imaging modality widely used to diagnose distal limb pathology in horses, but there are limited data regarding lesion distribution within the metacarpo/metatarsophalangeal joint (MCP/MTPJ) region ...

Abstract	Low-field, magnetic resonance imaging (MRI) is an advanced imaging modality widely used to diagnose distal limb pathology in horses, but there are limited data regarding lesion distribution within the metacarpo/metatarsophalangeal joint (MCP/MTPJ) region in lame nonracehorses. The aim of this study was to describe the low-field MRI findings and lesion distribution in nonracehorses with MCP/MTPJ region pain. Clinical records from horses undergoing MRI of the MCP/MTPJ region between July 2016 and March 2023 were reviewed. Horses were included if pain causing lameness was localized to this region and conventional imaging failed to provide a definitive diagnosis. Eighty-four horses met the inclusion criteria. Soft tissues were affected in 76 (90.5%) horses, with suspensory ligament branch injuries being the most frequent (60.7%) soft tissue pathology identified. Osseous pathology was diagnosed in 51 horses. The subchondral bone (SCB) of the distal third metacarpal/metatarsal bone (MC3/MT3) was the osseous structure most frequently affected (40.5%), with 79.4% of these horses having lesions on the dorsal aspect of the bone. Osteoarthritis was present in 48 (57.1%) horses. The main limitations of the study were the lack of a standardized diagnostic analgesia pattern due to varying veterinary surgeon involvement, and the absence of bilateral magnetic resonance (MR) sequences in all limbs. MRI is a useful diagnostic tool to assess soft tissue structures in the MCP/MTP region, especially in horses with thick skin, which may make ultrasonographic imaging unreliable.
MeSH term(s)	Horses ; Animals ; Joints ; Magnetic Resonance Imaging/veterinary ; Extremities ; Pain/veterinary
Language	English
Publishing date	2023-10-11
Publishing country	United States
Document type	Journal Article
ZDB-ID	2102631-2
ISSN	1542-7412 ; 0737-0806
ISSN (online)	1542-7412
ISSN	0737-0806
DOI	10.1016/j.jevs.2023.104938
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