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  1. Book: Manual of clinical microbiology / 2

    Versalovic, James

    2011  

    Author's details ed. in chief James Versalovic
    Collection Manual of clinical microbiology
    Language English
    Size XXVIII S., S. 1265 - 2314, S. XXIX - CLVII : Ill., graph. Darst.
    Publisher ASM Press
    Publishing place Washington, DC
    Publishing country United States
    Document type Book
    HBZ-ID HT016930762
    ISBN 978-1-555-81463-2 ; 1-555-81463-8
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

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    2008 A 7814 order for loan Magazin
    2011 A 3439 order for loan Magazin

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  2. Book: Manual of clinical microbiology / 1

    Versalovic, James

    2011  

    Author's details ed. in chief James Versalovic
    Collection Manual of clinical microbiology
    Language English
    Size XXVIII, 1261 S., S. XXIX - CLVII S. : Ill., graph. Darst.
    Publisher ASM Press
    Publishing place Washington, DC
    Publishing country United States
    Document type Book
    HBZ-ID HT016930758
    ISBN 978-1-55581-463-2 ; 1-55581-463-8
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2008 A 7813 order for loan Magazin
    2011 A 3438 order for loan Magazin

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  3. Book ; Collection: Manual of clinical microbiology

    Versalovic, James

    2011  

    Title variant Clinical microbiology
    Author's details ed. in chief James Versalovic
    Keywords Microbiology ; Microbiological Techniques
    Language English
    Dates of publication 2011-9999
    Edition 10. ed.
    Publisher ASM Press
    Publishing place Washington, DC
    Publishing country United States
    Document type Book ; Collection (display volumes)
    HBZ-ID HT016930756
    ISBN 978-1-55581-463-2 ; 1-55581-463-8
    Database Catalogue ZB MED Medicine, Health

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  4. Book: Therapeutic microbiology

    Versalovic, James

    probiotics and related strategies

    2008  

    Author's details ed. by James Versalovic
    Keywords Probiotics / therapeutic use ; Gastrointestinal Diseases / prevention & control ; Gastrointestinal Diseases / therapy ; Intestines / immunology ; Intestines / microbiology ; Probiotics ; Microorganisms/Therapeutic use
    Subject code 615.329
    Language English
    Size XVI, 403 S. : Ill., graph. Darst., 29cm
    Publisher ASM Press
    Publishing place Washington, DC
    Publishing country United States
    Document type Book
    Note Includes bibliographical references and index. - Formerly CIP
    HBZ-ID HT015704170
    ISBN 1-55581-403-4 ; 978-1-55581-403-8
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

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  5. Article ; Online: Taking a Closer Look at the Biogeography of the Human Gastrointestinal Microbiome.

    Engevik, Melinda / Versalovic, James

    Gastroenterology

    2019  Volume 157, Issue 4, Page(s) 927–929

    MeSH term(s) Bacteria ; Gastrointestinal Microbiome ; Gastrointestinal Tract ; Humans ; Microbiota
    Language English
    Publishing date 2019-08-07
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 80112-4
    ISSN 1528-0012 ; 0016-5085
    ISSN (online) 1528-0012
    ISSN 0016-5085
    DOI 10.1053/j.gastro.2019.08.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: The human microbiome and probiotics: implications for pediatrics.

    Versalovic, James

    Annals of nutrition & metabolism

    2013  Volume 63 Suppl 2, Page(s) 42–52

    Abstract: Steady advances in our knowledge of the composition and function of the human microbiome at multiple body sites including the gut, skin and airways will likely contribute to our understanding of mechanisms of probiotic action by beneficial microbes. ... ...

    Abstract Steady advances in our knowledge of the composition and function of the human microbiome at multiple body sites including the gut, skin and airways will likely contribute to our understanding of mechanisms of probiotic action by beneficial microbes. Microbe:microbe and microbe:human interactions are important considerations as we select probiotics for pediatric patients in the future. Although our knowledge about the composition of the microbiome is progressing rapidly, many gaps exist about the functional capacity and metabolic machinery of the human microbiome. Based on a limited amount of data, probiotics appear capable of altering the composition and function of the microbiome. Probiotics may be part of dietary strategies that combine ways to enhance microbiome function with nutrients that may be converted to active compounds promoting human health. Probiotics have yielded beneficial effects in numerous studies in the context of different diseases in pediatric gastroenterology. These disease states include necrotizing enterocolitis, antibiotic-associated diarrhea and colitis, acute gastroenteritis and irritable bowel syndrome. In the skin and airways, it is unclear if probiotics can affect the function of the microbiome to reduce the impact of diseases such as asthma and atopic dermatitis. An enhanced understanding of the effects of probiotics on the microbiome should facilitate selection of optimal probiotic strains for specific diseases in the future.
    MeSH term(s) Celiac Disease ; Child ; Clostridium difficile ; Diet ; Enterocolitis, Necrotizing ; Gastroenterology ; Humans ; Immunity ; Inflammatory Bowel Diseases ; Intestines/microbiology ; Irritable Bowel Syndrome ; Microbiota ; Pediatrics ; Probiotics
    Language English
    Publishing date 2013
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 392341-1
    ISSN 1421-9697 ; 0250-6807 ; 1018-9688
    ISSN (online) 1421-9697
    ISSN 0250-6807 ; 1018-9688
    DOI 10.1159/000354899
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Development of the Pediatric Gut Microbiome: Impact on Health and Disease.

    Ihekweazu, Faith D / Versalovic, James

    The American journal of the medical sciences

    2018  Volume 356, Issue 5, Page(s) 413–423

    Abstract: The intestinal microbiota are important in human growth and development. Microbial composition may yield insights into the temporal development of microbial communities and vulnerabilities to disorders of microbial ecology such as recurrent Clostridium ... ...

    Abstract The intestinal microbiota are important in human growth and development. Microbial composition may yield insights into the temporal development of microbial communities and vulnerabilities to disorders of microbial ecology such as recurrent Clostridium difficile infection. Discoveries of key microbiome features of carbohydrate and amino acid metabolism are lending new insights into possible therapies or preventative strategies for inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS). In this review, we summarize the current understanding of the development of the pediatric gastrointestinal microbiome, the influence of the microbiome on the developing brain through the gut-brain axis, and the impact of dysbiosis on disease development. Dysbiosis is explored in the context of pediatric allergy and asthma, recurrent C. difficile infection, IBD, IBS, and metabolic disorders. The central premise is that the human intestinal microbiome plays a vital role in health and disease, beginning in the prenatal period and extending throughout childhood.
    MeSH term(s) Adolescent ; Brain/growth & development ; Child ; Child, Preschool ; Disease/etiology ; Dysbiosis/etiology ; Gastrointestinal Microbiome ; Humans ; Infant ; Infant, Newborn
    Language English
    Publishing date 2018-08-21
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 82078-7
    ISSN 1538-2990 ; 0002-9629
    ISSN (online) 1538-2990
    ISSN 0002-9629
    DOI 10.1016/j.amjms.2018.08.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Microbial Metabolism in the Mammalian Gut: Molecular Mechanisms and Clinical Implications.

    Hall, Anne / Versalovic, James

    Journal of pediatric gastroenterology and nutrition

    2018  Volume 66 Suppl 3, Page(s) S72–S79

    Abstract: Human intestinal microbes participate actively at the interface of diet, nutrition, and overall health status. These biodiverse communities of microorganisms have a broader metabolic repertoire compared with their host, and they are able to synthesize ... ...

    Abstract Human intestinal microbes participate actively at the interface of diet, nutrition, and overall health status. These biodiverse communities of microorganisms have a broader metabolic repertoire compared with their host, and they are able to synthesize and degrade substrates that would be otherwise unavailable. In recent years, we have recognized that healthy microbial communities are important for energy harvest and the regulation of body systems outside the digestive tract. Microbial dysbiosis, however, has been implicated in a number of human disorders, including obesity and inflammation. This dichotomy highlights the need to understand the factors that determine the composition and metabolic output of our resident and transient microbes. Throughout the human lifespan, we know that diet plays a major role in shaping gut microbial communities, as well as directing the types and amounts of metabolites produced. Understanding the factors that affect microbial metabolic output within the host may help identify the roles of microbes in health, as well as new targets for treatment in disease. In this article, we review facets of the assembly and activities of the healthy human intestinal microbiome, as well as ways that the microbiota has been shown to influence the host via metabolism of two dietary macronutrients: carbohydrates and amino acids.
    MeSH term(s) Amino Acids/metabolism ; Animals ; Dietary Carbohydrates/metabolism ; Dysbiosis/physiopathology ; Gastrointestinal Microbiome/physiology ; Humans ; Intestines/microbiology ; Intestines/physiology
    Chemical Substances Amino Acids ; Dietary Carbohydrates
    Language English
    Publishing date 2018-07-02
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 603201-1
    ISSN 1536-4801 ; 0277-2116
    ISSN (online) 1536-4801
    ISSN 0277-2116
    DOI 10.1097/MPG.0000000000001857
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: From Z to A: Putting Zika virus in perspective.

    Teruya, Jun / Versalovic, James

    The Journal of thoracic and cardiovascular surgery

    2017  Volume 154, Issue 1, Page(s) 303–304

    MeSH term(s) Humans ; Zika Virus Infection/diagnosis ; Zika Virus Infection/prevention & control ; Zika Virus Infection/transmission
    Language English
    Publishing date 2017-02-09
    Publishing country United States
    Document type Editorial
    ZDB-ID 3104-5
    ISSN 1097-685X ; 0022-5223
    ISSN (online) 1097-685X
    ISSN 0022-5223
    DOI 10.1016/j.jtcvs.2016.11.074
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  10. Article ; Online: Biochemical Features of Beneficial Microbes: Foundations for Therapeutic Microbiology.

    Engevik, Melinda A / Versalovic, James

    Microbiology spectrum

    2017  Volume 5, Issue 5

    Abstract: Commensal and beneficial microbes secrete myriad products which target the mammalian host and other microbes. These secreted substances aid in bacterial niche development, and select compounds beneficially modulate the host and promote health. Microbes ... ...

    Abstract Commensal and beneficial microbes secrete myriad products which target the mammalian host and other microbes. These secreted substances aid in bacterial niche development, and select compounds beneficially modulate the host and promote health. Microbes produce unique compounds which can serve as signaling factors to the host, such as biogenic amine neuromodulators, or quorum-sensing molecules to facilitate inter-bacterial communication. Bacterial metabolites can also participate in functional enhancement of host metabolic capabilities, immunoregulation, and improvement of intestinal barrier function. Secreted products such as lactic acid, hydrogen peroxide, bacteriocins, and bacteriocin-like substances can also target the microbiome. Microbes differ greatly in their metabolic potential and subsequent host effects. As a result, knowledge about microbial metabolites will facilitate selection of next-generation probiotics and therapeutic compounds derived from the mammalian microbiome. In this article we describe prominent examples of microbial metabolites and their effects on microbial communities and the mammalian host.
    MeSH term(s) Animals ; Anti-Infective Agents/metabolism ; Bacteria/metabolism ; Bacteriocins/metabolism ; Extracellular Vesicles/metabolism ; Fatty Acids/metabolism ; Humans ; Hydrogen Peroxide/metabolism ; Lactic Acid/metabolism ; Metabolome ; Microbial Interactions ; Microbiota/physiology ; Neurotransmitter Agents/metabolism ; Polyamines/metabolism ; Probiotics/therapeutic use ; Serine Endopeptidases/metabolism ; Serpins/metabolism ; Signal Transduction ; Vitamins/metabolism
    Chemical Substances Anti-Infective Agents ; Bacteriocins ; Fatty Acids ; Neurotransmitter Agents ; Polyamines ; Serpins ; Vitamins ; Lactic Acid (33X04XA5AT) ; Hydrogen Peroxide (BBX060AN9V) ; Serine Endopeptidases (EC 3.4.21.-) ; lactocepin (EC 3.4.21.96)
    Language English
    Publishing date 2017-10-06
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2807133-5
    ISSN 2165-0497 ; 2165-0497
    ISSN (online) 2165-0497
    ISSN 2165-0497
    DOI 10.1128/microbiolspec.BAD-0012-2016
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