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  1. Article ; Online: The ALSFRS-R Summit: a global call to action on the use of the ALSFRS-R in ALS clinical trials.

    Genge, Angela / Cedarbaum, Jesse M / Shefner, Jeremy / Chio, Adriano / Al-Chalabi, Ammar / Van Damme, Philip / McDermott, Chris / Glass, Jonathan / Berry, James / van Eijk, Ruben P A / Fournier, Christina / Grosskreutz, Julian / Andrews, Jinsy / Bertone, Vanessa / Bunte, Tommy M / Couillard, Mathias / Cummings, Cathy / Kittle, Gale / Polzer, John /
    Salmon, Kristiana / Straub, Corey / van den Berg, Leonard H

    Amyotrophic lateral sclerosis & frontotemporal degeneration

    2024  Volume 25, Issue 3-4, Page(s) 382–387

    Abstract: ... revised and extended to meet the needs of high data quality in ALS trials (ALSFRS-R), however a full re ... of the ALSFRS-Revised scale in clinical trials, focusing on the need for (1) harmonization of the ALSFRS-R ...

    Abstract The Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS) was developed more than 25 years ago as an instrument to monitor functional change over time in patients with ALS. It has since been revised and extended to meet the needs of high data quality in ALS trials (ALSFRS-R), however a full re-validation of the scale was not completed. Despite this, the scale has remained a primary outcome measure in clinical trials. We convened a group of clinical trialists to discuss and explore opportunities to improve the scale and propose alternative measures. In this meeting report, we present a call to action on the use of the ALSFRS-Revised scale in clinical trials, focusing on the need for (1) harmonization of the ALSFRS-R administration globally, (2) alignment on a set of recommendations for clinical trial design and statistical analysis plans (SAPs), and (3) use of additional outcome measures.
    MeSH term(s) Humans ; Amyotrophic Lateral Sclerosis/diagnosis ; Amyotrophic Lateral Sclerosis/drug therapy ; Severity of Illness Index ; Disease Progression
    Language English
    Publishing date 2024-02-23
    Publishing country England
    Document type Journal Article
    ZDB-ID 2705049-X
    ISSN 2167-9223 ; 2167-8421
    ISSN (online) 2167-9223
    ISSN 2167-8421
    DOI 10.1080/21678421.2024.2320880
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: For R-eel?! Investigating international sales of critically endangered species in freshwater eel products with DNA barcoding

    Goymer, Amy / Steele, Kristen / Jenkins, Freddie / Burgess, Gemma / Andrews, Lucy / Baumgartner, Nina / Gubili, Chrysoula / Griffiths, Andrew Mark

    Food Control. 2023 Aug., v. 150 p.109752-

    2023  

    Abstract: The growing popularity of Japanese cuisine worldwide has caused an increasing demand for freshwater eels (family Anguillidae), usually termed 'unagi' and commonly utilised in sushi and donburi dishes. The trade of the Critically Endangered European eel ( ... ...

    Abstract The growing popularity of Japanese cuisine worldwide has caused an increasing demand for freshwater eels (family Anguillidae), usually termed 'unagi' and commonly utilised in sushi and donburi dishes. The trade of the Critically Endangered European eel (Anguilla anguilla) is now restricted and this has resulted in illegal trade. Here, DNA barcoding was used to identify the species of eel sold in processed eel products worldwide, including a focus on Europe and North America. For the first time, traditional jellied and stewed eel products from the UK are also barcoded. A total of 114 novel samples were analysed alongside previously published data to evaluate differences in species composition between locations, over time and in unagi versus more traditional UK eel products. The results revealed more European eel in East Asia than in Europe and more Japanese eel (Anguilla japonica) in the UK than East Asia - demonstrating a stark contrast between the native species and those commonly on sale (although variation in product type and eel recruitment influence this). This suggests thousands of food miles are potentially hidden in unagi products. Considering the limitations on export of the European eel, the numbers identified in products outside of its natural range bring into question the legality of supply. An increased prevalence of endangered American eel (Anguilla rostrata) was also shown globally. Future efforts should focus on implementing robust traceability systems, including using genetic methods, to deter illegal trade within the industry.
    Keywords Anguilla anguilla ; Anguilla japonica ; Anguilla rostrata ; DNA barcoding ; cuisine ; eel ; endangered species ; exports ; food safety ; freshwater ; indigenous species ; industry ; species diversity ; sushi ; traceability ; East Asia ; Europe ; North America ; European eel ; Japanese eel ; American Eel ; Unagi ; Jellied eel ; Stewed eel ; Anguilla ; DNA Barcode ; COI ; Umbrella label
    Language English
    Dates of publication 2023-08
    Publishing place Elsevier Ltd
    Document type Article ; Online
    Note Use and reproduction
    ZDB-ID 1027805-9
    ISSN 0956-7135
    ISSN 0956-7135
    DOI 10.1016/j.foodcont.2023.109752
    Database NAL-Catalogue (AGRICOLA)

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  3. Article ; Online: Validation of the C.A.R.E. stimulus set of 640 animal pictures: Name agreement and quality ratings.

    Russo, Natalie / Hagmann, Carl Erick / Andrews, Rosemary / Black, Conner / Silberman, Magenta / Shea, Nicole

    PloS one

    2018  Volume 13, Issue 2, Page(s) e0192906

    Abstract: Stimulus sets are valuable tools that can facilitate the work of researchers designing experiments. Images of faces, and line drawings of objects have been developed and validated, however, pictures of animals, that do not contain backgrounds, have not ... ...

    Abstract Stimulus sets are valuable tools that can facilitate the work of researchers designing experiments. Images of faces, and line drawings of objects have been developed and validated, however, pictures of animals, that do not contain backgrounds, have not been made available. Here we present image agreement and quality ratings for a set of 640 color images of animals on a transparent background, across 60 different basic categories (e.g. cat, dog, frog, bird), some with few, and others with many exemplars. These images were normed on 302 participants. Image agreement was measured both with respect to the proportion of participants that provided the same name as well as the H-statistic for each image. Image quality was measured both overall, and with respect to the accuracy of participants' naming of the basic category. Word frequency of each basic and superordinate category based on the English Lexicon Project (Balota, et al., 2007) and the HAL database (Kucera & Francis, 1976) are provided as are Age of Acquisition (Kuperman, Stadthagen-Gonzalez, & Brysbaert, 2012) data.
    MeSH term(s) Adolescent ; Animals ; Female ; Humans ; Male ; Names ; Photic Stimulation/methods ; Psychological Tests/statistics & numerical data ; Terminology as Topic ; Young Adult
    Language English
    Publishing date 2018-02-28
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Validation Study
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0192906
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Microbiome analysis as a platform R&D tool for parasitic nematode disease management.

    Hogan, Glenn / Walker, Sidney / Turnbull, Frank / Curiao, Tania / Morrison, Alison A / Flores, Yensi / Andrews, Leigh / Claesson, Marcus J / Tangney, Mark / Bartley, Dave J

    The ISME journal

    2019  Volume 13, Issue 11, Page(s) 2664–2680

    Abstract: The relationship between bacterial communities and their host is being extensively investigated for the potential to improve the host's health. Little is known about the interplay between the microbiota of parasites and the health of the infected host. ... ...

    Abstract The relationship between bacterial communities and their host is being extensively investigated for the potential to improve the host's health. Little is known about the interplay between the microbiota of parasites and the health of the infected host. Using nematode co-infection of lambs as a proof-of-concept model, the aim of this study was to characterise the microbiomes of nematodes and that of their host, enabling identification of candidate nematode-specific microbiota member(s) that could be exploited as drug development tools or for targeted therapy. Deep sequencing techniques were used to elucidate the microbiomes of different life stages of two parasitic nematodes of ruminants, Haemonchus contortus and Teladorsagia circumcincta, as well as that of the co-infected ovine hosts, pre- and post infection. Bioinformatic analyses demonstrated significant differences between the composition of the nematode and ovine microbiomes. The two nematode species also differed significantly. The data indicated a shift in the constitution of the larval nematode microbiome after exposure to the ovine microbiome, and in the ovine intestinal microbial community over time as a result of helminth co-infection. Several bacterial species were identified in nematodes that were absent from their surrounding abomasal environment, the most significant of which included Escherichia coli/Shigella. The ability to purposefully infect nematode species with engineered E. coli was demonstrated in vitro, validating the concept of using this bacterium as a nematode-specific drug development tool and/or drug delivery vehicle. To our knowledge, this is the first description of the concept of exploiting a parasite's microbiome for drug development and treatment purposes.
    MeSH term(s) Abomasum/microbiology ; Animals ; Bacteria/classification ; Biodiversity ; Disease Models, Animal ; Escherichia coli/genetics ; Genetic Engineering ; Haemonchus/microbiology ; High-Throughput Nucleotide Sequencing ; Microbiota ; Nematoda/microbiology ; Nematode Infections/parasitology ; Nematode Infections/therapy ; Nematode Infections/veterinary ; Sheep ; Sheep Diseases/parasitology ; Sheep Diseases/therapy
    Language English
    Publishing date 2019-06-25
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2406536-5
    ISSN 1751-7370 ; 1751-7362
    ISSN (online) 1751-7370
    ISSN 1751-7362
    DOI 10.1038/s41396-019-0462-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Genetic diversity and phylogenetic analyses of ixodid ticks infesting cattle in northeast Thailand: the discovery of Rhipicephalus microplus clade C and the rarely detected R. haemaphysaloides.

    Tantrawatpan, Chairat / Vaisusuk, Kotchaphon / Chatan, Wasupon / Pilap, Warayutt / Suksavate, Warong / Andrews, Ross H / Petney, Trevor N / Saijuntha, Weerachai

    Experimental & applied acarology

    2022  Volume 86, Issue 4, Page(s) 535–548

    Abstract: ... using the CO1 sequence revealed that the R. microplus from northeastern Thailand were grouped ... into the previously described clades A and C, whereas the 16S rRNA phylogenetic tree assigned all isolates of R ... detected in our study. The haplotype network also demonstrated that R. microplus is divided into two ...

    Abstract In total, 160 ticks infesting cattle in the northeast region of Thailand were collected and used for molecular investigation. Three tick species-Rhipicephalus microplus Canestrini, Rhipicephalus haemaphysaloides Supino and Haemaphysalis bispinosa Neumann-were identified based on morphology and DNA sequences of mitochondrial cytochrome c oxidase subunit 1 (CO1) and 16S ribosomal RNA (16S rRNA). In total, 26 and seven unique haplotypes of the CO1 and 16S rRNA genes, respectively, were recovered. Phylogenetic analysis using the CO1 sequence revealed that the R. microplus from northeastern Thailand were grouped into the previously described clades A and C, whereas the 16S rRNA phylogenetic tree assigned all isolates of R. microplus from Northeast Thailand into the previously described clade B. Clade C of the CO1 phylogenetic tree is a new genetic assemblage recently discovered from India and Malaysia, which has now been detected in our study. The haplotype network also demonstrated that R. microplus is divided into two haplogroups corresponding to the assemblage of the CO1 phylogenetic tree. Our findings strongly support the previous genetic assemblage classification and evidence that R. microplus from Northeast Thailand is a species complex comprising at least two genetic assemblages, i.e., clades A and C. However, further investigation is needed and should involve more comprehensive genetic and morphological analyses and cover a larger part of their distributional range throughout Southeast Asia.
    MeSH term(s) Animals ; Cattle ; Genetic Variation ; Ixodidae/genetics ; Phylogeny ; RNA, Ribosomal, 16S/genetics ; Rhipicephalus/genetics ; Thailand ; Tick Infestations/epidemiology ; Tick Infestations/veterinary
    Chemical Substances RNA, Ribosomal, 16S
    Language English
    Publishing date 2022-03-01
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 11320-7
    ISSN 1572-9702 ; 0168-8162
    ISSN (online) 1572-9702
    ISSN 0168-8162
    DOI 10.1007/s10493-022-00704-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Genetic diversity and phylogenetic analyses of ixodid ticks infesting cattle in northeast Thailand: the discovery of Rhipicephalus microplus clade C and the rarely detected R. haemaphysaloides

    Tantrawatpan, Chairat / Vaisusuk, Kotchaphon / Chatan, Wasupon / Pilap, Warayutt / Suksavate, Warong / Andrews, Ross H. / Petney, Trevor N. / Saijuntha, Weerachai

    Experimental & applied acarology. 2022 Apr., v. 86, no. 4

    2022  

    Abstract: ... using the CO1 sequence revealed that the R. microplus from northeastern Thailand were grouped ... into the previously described clades A and C, whereas the 16S rRNA phylogenetic tree assigned all isolates of R ... detected in our study. The haplotype network also demonstrated that R. microplus is divided into two ...

    Abstract In total, 160 ticks infesting cattle in the northeast region of Thailand were collected and used for molecular investigation. Three tick species—Rhipicephalus microplus Canestrini, Rhipicephalus haemaphysaloides Supino and Haemaphysalis bispinosa Neumann—were identified based on morphology and DNA sequences of mitochondrial cytochrome c oxidase subunit 1 (CO1) and 16S ribosomal RNA (16S rRNA). In total, 26 and seven unique haplotypes of the CO1 and 16S rRNA genes, respectively, were recovered. Phylogenetic analysis using the CO1 sequence revealed that the R. microplus from northeastern Thailand were grouped into the previously described clades A and C, whereas the 16S rRNA phylogenetic tree assigned all isolates of R. microplus from Northeast Thailand into the previously described clade B. Clade C of the CO1 phylogenetic tree is a new genetic assemblage recently discovered from India and Malaysia, which has now been detected in our study. The haplotype network also demonstrated that R. microplus is divided into two haplogroups corresponding to the assemblage of the CO1 phylogenetic tree. Our findings strongly support the previous genetic assemblage classification and evidence that R. microplus from Northeast Thailand is a species complex comprising at least two genetic assemblages, i.e., clades A and C. However, further investigation is needed and should involve more comprehensive genetic and morphological analyses and cover a larger part of their distributional range throughout Southeast Asia.
    Keywords Haemaphysalis ; Rhipicephalus microplus ; acarology ; cattle ; genetic variation ; haplotypes ; mitochondria ; phylogeny ; ribosomal RNA ; ticks ; India ; Malaysia ; Thailand
    Language English
    Dates of publication 2022-04
    Size p. 535-548.
    Publishing place Springer International Publishing
    Document type Article
    ZDB-ID 11320-7
    ISSN 1572-9702 ; 0168-8162
    ISSN (online) 1572-9702
    ISSN 0168-8162
    DOI 10.1007/s10493-022-00704-z
    Database NAL-Catalogue (AGRICOLA)

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  7. Article ; Online: Body mass index (BMI) as predictor of ALSFRS-R score decline in ALS patients.

    Reich-Slotky, Ronit / Andrews, Jinsy / Cheng, Bin / Buchsbaum, Richard / Levy, Diane / Kaufmann, Petra / Thompson, John L P

    Amyotrophic lateral sclerosis & frontotemporal degeneration

    2013  Volume 14, Issue 3, Page(s) 212–216

    Abstract: ... to decline in the revised Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS-R) score over time ... We used data from the high dose Coenzyme-Q10 in ALS (QALS) clinical trial, with in-person ALSFRS-R ... of BMI with the change of ALSFRS-R over time (p < 0.01). The smallest decline was at BMI of 30. Among non ...

    Abstract Recent studies of amyotrophic lateral sclerosis (ALS) suggest that body mass index (BMI) predicts patients' survival in a curvilinear manner. We sought to determine the relationship of initial BMI to decline in the revised Amyotrophic Lateral Sclerosis Functional Rating Scale (ALSFRS-R) score over time. We used data from the high dose Coenzyme-Q10 in ALS (QALS) clinical trial, with in-person ALSFRS-R interviews at baseline and nine months (n = 150). Multiple regression analysis allowed adjustment for a range of predictors. The final analysis, adjusted for age and FVC, indicated a significant, non-linear association of BMI with the change of ALSFRS-R over time (p < 0.01). The smallest decline was at BMI of 30. Among non-obese patients (BMI < 30, n = 126), higher BMI was associated with slower ALSFRS-R decline (p = 0.03). Among obese patients (BMI ≥ 30, n = 24), higher BMI was associated, although not significantly, with faster decline (p = 0.17). In conclusion, for ALS patient with BMI less than 30, higher initial BMI predicts slower functional decline. For patients with BMI greater than 30, higher initial BMI predicts more rapid decline. These results indicate that previous, apparently contradictory results can be reconciled, and suggest that initial BMI may help predict disease progression in ALS patients.
    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; Amyotrophic Lateral Sclerosis/diagnosis ; Amyotrophic Lateral Sclerosis/epidemiology ; Body Mass Index ; Disease Progression ; Female ; Humans ; Male ; Middle Aged ; Predictive Value of Tests ; Severity of Illness Index ; Young Adult
    Language English
    Publishing date 2013-04
    Publishing country England
    Document type Clinical Trial ; Journal Article ; Multicenter Study ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 2705049-X
    ISSN 2167-9223 ; 2167-8421
    ISSN (online) 2167-9223
    ISSN 2167-8421
    DOI 10.3109/21678421.2013.770028
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Discovery of ( R)-8-(6-Methyl-4-oxo-1,4,5,6-tetrahydropyrrolo[3,4- b]pyrrol-2-yl)-3-(1-methylcyclopropyl)-2-((1-methylcyclopropyl)amino)quinazolin-4(3 H)-one, a Potent and Selective Pim-1/2 Kinase Inhibitor for Hematological Malignancies.

    Wang, Hui-Ling / Andrews, Kristin L / Booker, Shon K / Canon, Jude / Cee, Victor J / Chavez, Frank / Chen, Yuping / Eastwood, Heather / Guerrero, Nadia / Herberich, Brad / Hickman, Dean / Lanman, Brian A / Laszlo, Jimmy / Lee, Matthew R / Lipford, J Russell / Mattson, Bethany / Mohr, Christopher / Nguyen, Yen / Norman, Mark H /
    Pettus, Liping H / Powers, David / Reed, Anthony B / Rex, Karen / Sastri, Christine / Tamayo, Nuria / Wang, Paul / Winston, Jeffrey T / Wu, Bin / Wu, Qiong / Wu, Tian / Wurz, Ryan P / Xu, Yang / Zhou, Yihong / Tasker, Andrew S

    Journal of medicinal chemistry

    2019  Volume 62, Issue 3, Page(s) 1523–1540

    Abstract: Pim kinases are a family of constitutively active serine/threonine kinases that are partially redundant and regulate multiple pathways important for cell growth and survival. In human disease, high expression of the three Pim isoforms has been implicated ...

    Abstract Pim kinases are a family of constitutively active serine/threonine kinases that are partially redundant and regulate multiple pathways important for cell growth and survival. In human disease, high expression of the three Pim isoforms has been implicated in the progression of hematopoietic and solid tumor cancers, which suggests that Pim kinase inhibitors could provide patients with therapeutic benefit. Herein, we describe the structure-guided optimization of a series of quinazolinone-pyrrolodihydropyrrolone analogs leading to the identification of potent pan-Pim inhibitor 28 with improved potency, solubility, and drug-like properties. Compound 28 demonstrated on-target Pim activity in an in vivo pharmacodynamic assay with significant inhibition of BAD phosphorylation in KMS-12-BM multiple myeloma tumors for 16 h postdose. In a 2-week mouse xenograft model, daily dosing of compound 28 resulted in 33% tumor regression at 100 mg/kg.
    MeSH term(s) Animals ; Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/pharmacokinetics ; Antineoplastic Agents/therapeutic use ; Female ; Hematologic Neoplasms/drug therapy ; Humans ; Mice, SCID ; Molecular Structure ; Protein Kinase Inhibitors/chemical synthesis ; Protein Kinase Inhibitors/pharmacokinetics ; Protein Kinase Inhibitors/therapeutic use ; Proto-Oncogene Proteins c-pim-1/antagonists & inhibitors ; Pyrroles/chemical synthesis ; Pyrroles/pharmacokinetics ; Pyrroles/therapeutic use ; Quinazolinones/chemical synthesis ; Quinazolinones/pharmacokinetics ; Quinazolinones/therapeutic use ; Structure-Activity Relationship ; Swine ; Xenograft Model Antitumor Assays
    Chemical Substances Antineoplastic Agents ; Protein Kinase Inhibitors ; Pyrroles ; Quinazolinones ; Proto-Oncogene Proteins c-pim-1 (EC 2.7.11.1)
    Language English
    Publishing date 2019-01-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 218133-2
    ISSN 1520-4804 ; 0022-2623
    ISSN (online) 1520-4804
    ISSN 0022-2623
    DOI 10.1021/acs.jmedchem.8b01733
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Discovery of 1H-pyrazol-3(2H)-ones as potent and selective inhibitors of protein kinase R-like endoplasmic reticulum kinase (PERK).

    Smith, Adrian L / Andrews, Kristin L / Beckmann, Holger / Bellon, Steven F / Beltran, Pedro J / Booker, Shon / Chen, Hao / Chung, Young-Ah / D'Angelo, Noel D / Dao, Jennifer / Dellamaggiore, Kenneth R / Jaeckel, Peter / Kendall, Richard / Labitzke, Katja / Long, Alexander M / Materna-Reichelt, Silvia / Mitchell, Petia / Norman, Mark H / Powers, David /
    Rose, Mark / Shaffer, Paul L / Wu, Michelle M / Lipford, J Russell

    Journal of medicinal chemistry

    2015  Volume 58, Issue 3, Page(s) 1426–1441

    Abstract: The structure-based design and optimization of a novel series of selective PERK inhibitors are described resulting in the identification of 44 as a potent, highly selective, and orally active tool compound suitable for PERK pathway biology exploration ... ...

    Abstract The structure-based design and optimization of a novel series of selective PERK inhibitors are described resulting in the identification of 44 as a potent, highly selective, and orally active tool compound suitable for PERK pathway biology exploration both in vitro and in vivo.
    MeSH term(s) Animals ; Cells, Cultured ; Dose-Response Relationship, Drug ; Drug Discovery ; Humans ; Mice ; Mice, Nude ; Models, Molecular ; Molecular Structure ; Protein Kinase Inhibitors/chemical synthesis ; Protein Kinase Inhibitors/chemistry ; Protein Kinase Inhibitors/pharmacology ; Pyrazoles/chemical synthesis ; Pyrazoles/chemistry ; Pyrazoles/pharmacology ; Structure-Activity Relationship ; eIF-2 Kinase/antagonists & inhibitors ; eIF-2 Kinase/metabolism
    Chemical Substances Protein Kinase Inhibitors ; Pyrazoles ; EIF2AK3 protein, human (EC 2.7.11.1) ; eIF-2 Kinase (EC 2.7.11.1)
    Language English
    Publishing date 2015-02-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 218133-2
    ISSN 1520-4804 ; 0022-2623
    ISSN (online) 1520-4804
    ISSN 0022-2623
    DOI 10.1021/jm5017494
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Search for top squarks in R-parity-violating supersymmetry using three or more leptons and b-tagged jets.

    Chatrchyan, S / Khachatryan, V / Sirunyan, A M / Tumasyan, A / Adam, W / Bergauer, T / Dragicevic, M / Erö, J / Fabjan, C / Friedl, M / Frühwirth, R / Ghete, V M / Hörmann, N / Hrubec, J / Jeitler, M / Kiesenhofer, W / Knünz, V / Krammer, M / Krätschmer, I /
    Liko, D / Mikulec, I / Rabady, D / Rahbaran, B / Rohringer, C / Rohringer, H / Schöfbeck, R / Strauss, J / Taurok, A / Treberer-Treberspurg, W / Waltenberger, W / Wulz, C-E / Mossolov, V / Shumeiko, N / Suarez Gonzalez, J / Alderweireldt, S / Bansal, M / Bansal, S / Cornelis, T / De Wolf, E A / Janssen, X / Knutsson, A / Luyckx, S / Mucibello, L / Ochesanu, S / Roland, B / Rougny, R / Staykova, Z / Van Haevermaet, H / Van Mechelen, P / Van Remortel, N / Van Spilbeeck, A / Blekman, F / Blyweert, S / D'Hondt, J / Kalogeropoulos, A / Keaveney, J / Maes, M / Olbrechts, A / Tavernier, S / Van Doninck, W / Van Mulders, P / Van Onsem, G P / Villella, I / Clerbaux, B / De Lentdecker, G / Favart, L / Gay, A P R / Hreus, T / Léonard, A / Marage, P E / Mohammadi, A / Perniè, L / Reis, T / Seva, T / Thomas, L / Vander Velde, C / Vanlaer, P / Wang, J / Adler, V / Beernaert, K / Benucci, L / Cimmino, A / Costantini, S / Dildick, S / Garcia, G / Klein, B / Lellouch, J / Marinov, A / McCartin, J / Ocampo Rios, A A / Ryckbosch, D / Sigamani, M / Strobbe, N / Thyssen, F / Tytgat, M / Walsh, S / Yazgan, E / Zaganidis, N / Basegmez, S / Beluffi, C / Bruno, G / Castello, R / Caudron, A / Ceard, L / Delaere, C / du Pree, T / Favart, D / Forthomme, L / Giammanco, A / Hollar, J / Jez, P / Lemaitre, V / Liao, J / Militaru, O / Nuttens, C / Pagano, D / Pin, A / Piotrzkowski, K / Popov, A / Selvaggi, M / Vizan Garcia, J M / Beliy, N / Caebergs, T / Daubie, E / Hammad, G H / Alves, G A / Correa Martins Junior, M / Martins, T / Pol, M E / Souza, M H G / Aldá Júnior, W L / Carvalho, W / Chinellato, J / Custódio, A / Da Costa, E M / De Jesus Damiao, D / De Oliveira Martins, C / Fonseca De Souza, S / Malbouisson, H / Malek, M / Matos Figueiredo, D / Mundim, L / Nogima, H / Prado Da Silva, W L / Santoro, A / Sznajder, A / Tonelli Manganote, E J / Vilela Pereira, A / Bernardes, C A / Dias, F A / Fernandez Perez Tomei, T R / Gregores, E M / Lagana, C / Mercadante, P G / Novaes, S F / Padula, Sandra S / Genchev, V / Iaydjiev, P / Piperov, S / Rodozov, M / Sultanov, G / Vutova, M / Dimitrov, A / Hadjiiska, R / Kozhuharov, V / Litov, L / Pavlov, B / Petkov, P / Bian, J G / Chen, G M / Chen, H S / Jiang, C H / Liang, D / Liang, S / Meng, X / Tao, J / Wang, X / Wang, Z / Xiao, H / Xu, M / Asawatangtrakuldee, C / Ban, Y / Guo, Y / Li, Q / Li, W / Liu, S / Mao, Y / Qian, S J / Wang, D / Zhang, L / Zou, W / Avila, C / Carrillo Montoya, C A / Chaparro Sierra, L F / Gomez, J P / Gomez Moreno, B / Sanabria, J C / Godinovic, N / Lelas, D / Plestina, R / Polic, D / Puljak, I / Antunovic, Z / Kovac, M / Brigljevic, V / Duric, S / Kadija, K / Luetic, J / Mekterovic, D / Morovic, S / Tikvica, L / Attikis, A / Mavromanolakis, G / Mousa, J / Nicolaou, C / Ptochos, F / Razis, P A / Finger, M / Abdelalim, A A / Assran, Y / Elgammal, S / Ellithi Kamel, A / Mahmoud, M A / Radi, A / Kadastik, M / Müntel, M / Murumaa, M / Raidal, M / Rebane, L / Tiko, A / Eerola, P / Fedi, G / Voutilainen, M / Härkönen, J / Karimäki, V / Kinnunen, R / Kortelainen, M J / Lampén, T / Lassila-Perini, K / Lehti, S / Lindén, T / Luukka, P / Mäenpää, T / Peltola, T / Tuominen, E / Tuominiemi, J / Tuovinen, E / Wendland, L / Tuuva, T / Besancon, M / Choudhury, S / Couderc, F / Dejardin, M / Denegri, D / Fabbro, B / Faure, J L / Ferri, F / Ganjour, S / Givernaud, A / Gras, P / Hamel de Monchenault, G / Jarry, P / Locci, E / Malcles, J / Millischer, L / Nayak, A / Rander, J / Rosowsky, A / Titov, M / Baffioni, S / Beaudette, F / Benhabib, L / Bianchini, L / Bluj, M / Busson, P / Charlot, C / Daci, N / Dahms, T / Dalchenko, M / Dobrzynski, L / Florent, A / Granier de Cassagnac, R / Haguenauer, M / Miné, P / Mironov, C / Naranjo, I N / Nguyen, M / Ochando, C / Paganini, P / Sabes, D / Salerno, R / Sirois, Y / Veelken, C / Zabi, A / Agram, J-L / Andrea, J / Bloch, D / Bodin, D / Brom, J-M / Chabert, E C / Collard, C / Conte, E / Drouhin, F / Fontaine, J-C / Gelé, D / Goerlach, U / Goetzmann, C / Juillot, P / Le Bihan, A-C / Van Hove, P / Gadrat, S / Beauceron, S / Beaupere, N / Boudoul, G / Brochet, S / Chasserat, J / Chierici, R / Contardo, D / Depasse, P / El Mamouni, H / Fay, J / Gascon, S / Gouzevitch, M / Ille, B / Kurca, T / Lethuillier, M / Mirabito, L / Perries, S / Sgandurra, L / Sordini, V / Tschudi, Y / Vander Donckt, M / Verdier, P / Viret, S / Tsamalaidze, Z / Autermann, C / Beranek, S / Calpas, B / Edelhoff, M / Feld, L / Heracleous, N / Hindrichs, O / Klein, K / Ostapchuk, A / Perieanu, A / Raupach, F / Sammet, J / Schael, S / Sprenger, D / Weber, H / Wittmer, B / Zhukov, V / Ata, M / Caudron, J / Dietz-Laursonn, E / Duchardt, D / Erdmann, M / Fischer, R / Güth, A / Hebbeker, T / Heidemann, C / Hoepfner, K / Klingebiel, D / Kreuzer, P / Merschmeyer, M / Meyer, A / Olschewski, M / Padeken, K / Papacz, P / Pieta, H / Reithler, H / Schmitz, S A / Sonnenschein, L / Steggemann, J / Teyssier, D / Thüer, S / Weber, M / Cherepanov, V / Erdogan, Y / Flügge, G / Geenen, H / Geisler, M / Haj Ahmad, W / Hoehle, F / Kargoll, B / Kress, T / Kuessel, Y / Lingemann, J / Nowack, A / Nugent, I M / Perchalla, L / Pooth, O / Stahl, A / Aldaya Martin, M / Asin, I / Bartosik, N / Behr, J / Behrenhoff, W / Behrens, U / Bergholz, M / Bethani, A / Borras, K / Burgmeier, A / Cakir, A / Calligaris, L / Campbell, A / Costanza, F / Diez Pardos, C / Dooling, S / Dorland, T / Eckerlin, G / Eckstein, D / Flucke, G / Geiser, A / Glushkov, I / Gunnellini, P / Habib, S / Hauk, J / Hellwig, G / Horton, D / Jung, H / Kasemann, M / Katsas, P / Kleinwort, C / Kluge, H / Krämer, M / Krücker, D / Kuznetsova, E / Lange, W / Leonard, J / Lipka, K / Lohmann, W / Lutz, B / Mankel, R / Marfin, I / Melzer-Pellmann, I-A / Meyer, A B / Mnich, J / Mussgiller, A / Naumann-Emme, S / Novgorodova, O / Nowak, F / Olzem, J / Perrey, H / Petrukhin, A / Pitzl, D / Placakyte, R / Raspereza, A / Ribeiro Cipriano, P M / Riedl, C / Ron, E / Sahin, M Ö / Salfeld-Nebgen, J / Schmidt, R / Schoerner-Sadenius, T / Sen, N / Stein, M / Walsh, R / Wissing, C / Blobel, V / Enderle, H / Erfle, J / Gebbert, U / Görner, M / Gosselink, M / Haller, J / Heine, K / Höing, R S / Kaussen, G / Kirschenmann, H / Klanner, R / Kogler, R / Lange, J / Marchesini, I / Peiffer, T / Pietsch, N / Rathjens, D / Sander, C / Schettler, H / Schleper, P / Schlieckau, E / Schmidt, A / Schröder, M / Schum, T / Seidel, M / Sibille, J / Sola, V / Stadie, H / Steinbrück, G / Thomsen, J / Troendle, D / Vanelderen, L / Barth, C / Baus, C / Berger, J / Böser, C / Butz, E / Chwalek, T / De Boer, W / Descroix, A / Dierlamm, A / Feindt, M / Guthoff, M / Hartmann, F / Hauth, T / Held, H / Hoffmann, K H / Husemann, U / Katkov, I / Komaragiri, J R / Kornmayer, A / Lobelle Pardo, P / Martschei, D / Müller, Th / Niegel, M / Nürnberg, A / Oberst, O / Ott, J / Quast, G / Rabbertz, K / Ratnikov, F / Röcker, S / Schilling, F-P / Schott, G / Simonis, H J / Stober, F M / Ulrich, R / Wagner-Kuhr, J / Wayand, S / Weiler, T / Zeise, M / Anagnostou, G / Daskalakis, G / Geralis, T / Kesisoglou, S / Kyriakis, A / Loukas, D / Markou, A / Markou, C / Ntomari, E / Gouskos, L / Mertzimekis, T J / Panagiotou, A / Saoulidou, N / Stiliaris, E / Aslanoglou, X / Evangelou, I / Flouris, G / Foudas, C / Kokkas, P / Manthos, N / Papadopoulos, I / Paradas, E / Bencze, G / Hajdu, C / Hidas, P / Horvath, D / Radics, B / Sikler, F / Veszpremi, V / Vesztergombi, G / Zsigmond, A J / Beni, N / Czellar, S / Molnar, J / Palinkas, J / Szillasi, Z / Karancsi, J / Raics, P / Trocsanyi, Z L / Ujvari, B / Swain, S K / Beri, S B / Bhatnagar, V / Dhingra, N / Gupta, R / Kaur, M / Mehta, M Z / Mittal, M / Nishu, N / Saini, L K / Sharma, A / Singh, J B / Kumar, Ashok / Kumar, Arun / Ahuja, S / Bhardwaj, A / Choudhary, B C / Malhotra, S / Naimuddin, M / Ranjan, K / Saxena, P / Sharma, V / Shivpuri, R K / Banerjee, S / Bhattacharya, S / Chatterjee, K / Dutta, S / Gomber, B / Jain, Sa / Jain, Sh / Khurana, R / Modak, A / Mukherjee, S / Roy, D / Sarkar, S / Sharan, M / Abdulsalam, A / Dutta, D / Kailas, S / Kumar, V / Mohanty, A K / Pant, L M / Shukla, P / Topkar, A / Aziz, T / Chatterjee, R M / Ganguly, S / Ghosh, S / Guchait, M / Gurtu, A / Kole, G / Kumar, S / Maity, M / Majumder, G / Mazumdar, K / Mohanty, G B / Parida, B / Sudhakar, K / Wickramage, N / Dugad, S / Arfaei, H / Bakhshiansohi, H / Etesami, S M / Fahim, A / Hesari, H / Jafari, A / Khakzad, M / Mohammadi Najafabadi, M / Paktinat Mehdiabadi, S / Safarzadeh, B / Zeinali, M / Grunewald, M / Abbrescia, M / Barbone, L / Calabria, C / Chhibra, S S / Colaleo, A / Creanza, D / De Filippis, N / De Palma, M / Fiore, L / Iaselli, G / Maggi, G / Maggi, M / Marangelli, B / My, S / Nuzzo, S / Pacifico, N / Pompili, A / Pugliese, G / Selvaggi, G / Silvestris, L / Singh, G / Venditti, R / Verwilligen, P / Zito, G / Abbiendi, G / Benvenuti, A C / Bonacorsi, D / Braibant-Giacomelli, S / Brigliadori, L / Campanini, R / Capiluppi, P / Castro, A / Cavallo, F R / Cuffiani, M / Dallavalle, G M / Fabbri, F / Fanfani, A / Fasanella, D / Giacomelli, P / Grandi, C / Guiducci, L / Marcellini, S / Masetti, G / Meneghelli, M / Montanari, A / Navarria, F L / Odorici, F / Perrotta, A / Primavera, F / Rossi, A M / Rovelli, T / Siroli, G P / Tosi, N / Travaglini, R / Albergo, S / Chiorboli, M / Costa, S / Giordano, F / Potenza, R / Tricomi, A / Tuve, C / Barbagli, G / Ciulli, V / Civinini, C / D'Alessandro, R / Focardi, E / Frosali, S / Gallo, E / Gonzi, S / Gori, V / Lenzi, P / Meschini, M / Paoletti, S / Sguazzoni, G / Tropiano, A / Benussi, L / Bianco, S / Piccolo, D / Fabbricatore, P / Musenich, R / Tosi, S / Benaglia, A / De Guio, F / Di Matteo, L / Fiorendi, S / Gennai, S / Ghezzi, A / Govoni, P / Lucchini, M T / Malvezzi, S / Manzoni, R A / Martelli, A / Menasce, D / Moroni, L / Paganoni, M / Pedrini, D / Ragazzi, S / Redaelli, N / Tabarelli de Fatis, T / Buontempo, S / Cavallo, N / De Cosa, A / Fabozzi, F / Iorio, A O M / Lista, L / Meola, S / Merola, M / Paolucci, P / Azzi, P / Bacchetta, N / Bisello, D / Branca, A / Carlin, R / Checchia, P / Dorigo, T / Dosselli, U / Galanti, M / Gasparini, F / Gasparini, U / Giubilato, P / Gozzelino, A / Kanishchev, K / Lacaprara, S / Lazzizzera, I / Margoni, M / Meneguzzo, A T / Montecassiano, F / Passaseo, M / Pazzini, J / Pegoraro, M / Pozzobon, N / Ronchese, P / Simonetto, F / Torassa, E / Tosi, M / Triossi, A / Zotto, P / Zumerle, G / Gabusi, M / Ratti, S P / Riccardi, C / Vitulo, P / Biasini, M / Bilei, G M / Fanò, L / Lariccia, P / Mantovani, G / Menichelli, M / Nappi, A / Romeo, F / Saha, A / Santocchia, A / Spiezia, A / Androsov, K / Azzurri, P / Bagliesi, G / Bernardini, J / Boccali, T / Broccolo, G / Castaldi, R / D'Agnolo, R T / Dell'Orso, R / Fiori, F / Foà, L / Giassi, A / Grippo, M T / Kraan, A / Ligabue, F / Lomtadze, T / Martini, L / Messineo, A / Palla, F / Rizzi, A / Serban, A T / Spagnolo, P / Squillacioti, P / Tenchini, R / Tonelli, G / Venturi, A / Verdini, P G / Vernieri, C / Barone, L / Cavallari, F / Del Re, D / Diemoz, M / Grassi, M / Longo, E / Margaroli, F / Meridiani, P / Micheli, F / Nourbakhsh, S / Organtini, G / Paramatti, R / Rahatlou, S / Soffi, L / Amapane, N / Arcidiacono, R / Argiro, S / Arneodo, M / Biino, C / Cartiglia, N / Casasso, S / Costa, M / Demaria, N / Mariotti, C / Maselli, S / Migliore, E / Monaco, V / Musich, M / Obertino, M M / Ortona, G / Pastrone, N / Pelliccioni, M / Potenza, A / Romero, A / Ruspa, M / Sacchi, R / Solano, A / Staiano, A / Tamponi, U / Belforte, S / Candelise, V / Casarsa, M / Cossutti, F / Della Ricca, G / Gobbo, B / La Licata, C / Marone, M / Montanino, D / Penzo, A / Schizzi, A / Zanetti, A / Chang, S / Kim, T Y / Nam, S K / Kim, D H / Kim, G N / Kim, J E / Kong, D J / Oh, Y D / Park, H / Son, D C / Kim, J Y / Kim, Zero J / Song, S / Choi, S / Gyun, D / Hong, B / Jo, M / Kim, H / Kim, T J / Lee, K S / Park, S K / Roh, Y / Choi, M / Kim, J H / Park, C / Park, I C / Park, S / Ryu, G / Choi, Y / Choi, Y K / Goh, J / Kim, M S / Kwon, E / Lee, B / Lee, J / Lee, S / Seo, H / Yu, I / Grigelionis, I / Juodagalvis, A / Castilla-Valdez, H / De La Cruz-Burelo, E / Heredia-de La Cruz, I / Lopez-Fernandez, R / Martínez-Ortega, J / Sanchez-Hernandez, A / Villasenor-Cendejas, L M / Carrillo Moreno, S / Vazquez Valencia, F / Salazar Ibarguen, H A / Casimiro Linares, E / Morelos Pineda, A / Reyes-Santos, M A / Krofcheck, D / Bell, A J / Butler, P H / Doesburg, R / Reucroft, S / Silverwood, H / Ahmad, M / Asghar, M I / Butt, J / Hoorani, H R / Khalid, S / Khan, W A / Khurshid, T / Qazi, S / Shah, M A / Shoaib, M / Bialkowska, H / Boimska, B / Frueboes, T / Górski, M / Kazana, M / Nawrocki, K / Romanowska-Rybinska, K / Szleper, M / Wrochna, G / Zalewski, P / Brona, G / Bunkowski, K / Cwiok, M / Dominik, W / Doroba, K / Kalinowski, A / Konecki, M / Krolikowski, J / Misiura, M / Wolszczak, W / Almeida, N / Bargassa, P / Beirão Da Cruz E Silva, C / Faccioli, P / Ferreira Parracho, P G / Gallinaro, M / Rodrigues Antunes, J / Seixas, J / Varela, J / Vischia, P / Afanasiev, S / Bunin, P / Golutvin, I / Gorbunov, I / Kamenev, A / Karjavin, V / Konoplyanikov, V / Kozlov, G / Lanev, A / Malakhov, A / Matveev, V / Moisenz, P / Palichik, V / Perelygin, V / Shmatov, S / Skatchkov, N / Smirnov, V / Zarubin, A / Evstyukhin, S / Golovtsov, V / Ivanov, Y / Kim, V / Levchenko, P / Murzin, V / Oreshkin, V / Smirnov, I / Sulimov, V / Uvarov, L / Vavilov, S / Vorobyev, A / Vorobyev, An / Andreev, Yu / Dermenev, A / Gninenko, S / Golubev, N / Kirsanov, M / Krasnikov, N / Pashenkov, A / Tlisov, D / Toropin, A / Epshteyn, V / Erofeeva, M / Gavrilov, V / Lychkovskaya, N / Popov, V / Safronov, G / Semenov, S / Spiridonov, A / Stolin, V / Vlasov, E / Zhokin, A / Andreev, V / Azarkin, M / Dremin, I / Kirakosyan, M / Leonidov, A / Mesyats, G / Rusakov, S V / Vinogradov, A / Belyaev, A / Boos, E / Bunichev, V / Dubinin, M / Dudko, L / Ershov, A / Gribushin, A / Klyukhin, V / Kodolova, O / Lokhtin, I / Markina, A / Obraztsov, S / Savrin, V / Snigirev, A / Azhgirey, I / Bayshev, I / Bitioukov, S / Kachanov, V / Kalinin, A / Konstantinov, D / Krychkine, V / Petrov, V / Ryutin, R / Sobol, A / Tourtchanovitch, L / Troshin, S / Tyurin, N / Uzunian, A / Volkov, A / Adzic, P / Djordjevic, M / Ekmedzic, M / Krpic, D / Milosevic, J / Aguilar-Benitez, M / Alcaraz Maestre, J / Battilana, C / Calvo, E / Cerrada, M / Chamizo Llatas, M / Colino, N / De La Cruz, B / Delgado Peris, A / Domínguez Vázquez, D / Fernandez Bedoya, C / Fernández Ramos, J P / Ferrando, A / Flix, J / Fouz, M C / Garcia-Abia, P / Gonzalez Lopez, O / Goy Lopez, S / Hernandez, J M / Josa, M I / Merino, G / Navarro De Martino, E / Puerta Pelayo, J / Quintario Olmeda, A / Redondo, I / Romero, L / Santaolalla, J / Soares, M S / Willmott, C / Albajar, C / de Trocóniz, J F / Brun, H / Cuevas, J / Fernandez Menendez, J / Folgueras, S / Gonzalez Caballero, I / Lloret Iglesias, L / Piedra Gomez, J / Brochero Cifuentes, J A / Cabrillo, I J / Calderon, A / Chuang, S H / Duarte Campderros, J / Fernandez, M / Gomez, G / Gonzalez Sanchez, J / Graziano, A / Jorda, C / Lopez Virto, A / Marco, J / Marco, R / Martinez Rivero, C / Matorras, F / Munoz Sanchez, F J / Rodrigo, T / Rodríguez-Marrero, A Y / Ruiz-Jimeno, A / Scodellaro, L / Vila, I / Vilar Cortabitarte, R / Abbaneo, D / Auffray, E / Auzinger, G / Bachtis, M / Baillon, P / Ball, A H / Barney, D / Bendavid, J / Benitez, J F / Bernet, C / Bianchi, G / Bloch, P / Bocci, A / Bonato, A / Bondu, O / Botta, C / Breuker, H / Camporesi, T / Cerminara, G / Christiansen, T / Coarasa Perez, J A / Colafranceschi, S / d'Enterria, D / Dabrowski, A / David, A / De Roeck, A / De Visscher, S / Di Guida, S / Dobson, M / Dupont-Sagorin, N / Elliott-Peisert, A / Eugster, J / Funk, W / Georgiou, G / Giffels, M / Gigi, D / Gill, K / Giordano, D / Girone, M / Giunta, M / Glege, F / Gomez-Reino Garrido, R / Gowdy, S / Guida, R / Hammer, J / Hansen, M / Harris, P / Hartl, C / Hinzmann, A / 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    Physical review letters

    2013  Volume 111, Issue 22, Page(s) 221801

    Abstract: ... production with R-parity-violating decays of the lightest supersymmetric particle. In two models ... with different R-parity-violating couplings, top squarks are excluded below masses of 1020 GeV and 820 GeV ...

    Abstract A search for anomalous production of events with three or more isolated leptons and bottom-quark jets produced in pp collisions at √s=8 TeV is presented. The analysis is based on a data sample corresponding to an integrated luminosity of 19.5 fb(-1) collected by the CMS experiment at the LHC in 2012. No excess above the standard model expectations is observed. The results are interpreted in the context of supersymmetric models with signatures that have low missing transverse energy arising from light top-squark pair production with R-parity-violating decays of the lightest supersymmetric particle. In two models with different R-parity-violating couplings, top squarks are excluded below masses of 1020 GeV and 820 GeV when the lightest supersymmetric particle has a mass of 200 GeV.
    Language English
    Publishing date 2013-11-27
    Publishing country United States
    Document type Journal Article
    ZDB-ID 208853-8
    ISSN 1079-7114 ; 0031-9007
    ISSN (online) 1079-7114
    ISSN 0031-9007
    DOI 10.1103/PhysRevLett.111.221801
    Database MEDical Literature Analysis and Retrieval System OnLINE

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