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Article: Hematopoietic stem and progenitor cells directly participate in host immune response.

Daramola, Olusola Jumoke / Osasan, Stephen / Ali, Hebah / Emeagi, Perpetua

American journal of stem cells

2021  Volume 10, Issue 2, Page(s) 18–27

Abstract: The properties of hematopoietic stem and progenitor cells (HSPCs), including self-renewal and pluripotency, have been extensively studied. These features have been explored in the management of several haematological disorders and malignancies. Although ... ...

Abstract The properties of hematopoietic stem and progenitor cells (HSPCs), including self-renewal and pluripotency, have been extensively studied. These features have been explored in the management of several haematological disorders and malignancies. Although their role as precursors of innate immune cells is well understood, little is known about their direct participation in host immune response. In this review, we explicate the direct role of HSPCs in the host immune response and highlight therapeutic options for the infectious disease burden that is currently ravaging the world, including COVID-19.
Language English
Publishing date 2021-06-15
Publishing country United States
Document type Journal Article ; Review
ZDB-ID 2708996-4
ISSN 2160-4150
ISSN 2160-4150
Database MEDical Literature Analysis and Retrieval System OnLINE

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