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  1. Article ; Online: Attenuation of exercise conditioning by metformin-a consequence of HSF1 inhibition.

    Hooper, Philip L

    Cell stress & chaperones

    2022  Volume 27, Issue 4, Page(s) 307

    MeSH term(s) DNA-Binding Proteins/metabolism ; Heat Shock Transcription Factors ; Metformin/pharmacology ; Transcription Factors/metabolism
    Chemical Substances DNA-Binding Proteins ; Heat Shock Transcription Factors ; Transcription Factors ; Metformin (9100L32L2N)
    Language English
    Publishing date 2022-05-10
    Publishing country Netherlands
    Document type Letter
    ZDB-ID 1362749-1
    ISSN 1466-1268 ; 1355-8145
    ISSN (online) 1466-1268
    ISSN 1355-8145
    DOI 10.1007/s12192-022-01276-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4797: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Heme oxygenase agonists-fluvoxamine, melatonin-are efficacious therapy for Covid-19.

    Hooper, Philip L

    Cell stress & chaperones

    2021  Volume 27, Issue 1, Page(s) 3–4

    MeSH term(s) Fluvoxamine/therapeutic use ; Heme Oxygenase (Decyclizing)/metabolism ; Humans ; Melatonin/therapeutic use ; SARS-CoV-2/drug effects ; COVID-19 Drug Treatment
    Chemical Substances Heme Oxygenase (Decyclizing) (EC 1.14.14.18) ; Melatonin (JL5DK93RCL) ; Fluvoxamine (O4L1XPO44W)
    Language English
    Publishing date 2021-11-30
    Publishing country Netherlands
    Document type Letter
    ZDB-ID 1362749-1
    ISSN 1466-1268 ; 1355-8145
    ISSN (online) 1466-1268
    ISSN 1355-8145
    DOI 10.1007/s12192-021-01246-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4797: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  3. Article ; Online: Correction to: COVID-19 and heme oxygenase: novel insight into the disease and potential therapies.

    Hooper, Philip L

    Cell stress & chaperones

    2020  Volume 25, Issue 5, Page(s) 711

    Abstract: In the original publication, one of the last paragraphs should have read as follows. ...

    Abstract In the original publication, one of the last paragraphs should have read as follows.
    Keywords covid19
    Language English
    Publishing date 2020-07-09
    Publishing country Netherlands
    Document type Journal Article ; Published Erratum
    ZDB-ID 1362749-1
    ISSN 1466-1268 ; 1355-8145
    ISSN (online) 1466-1268
    ISSN 1355-8145
    DOI 10.1007/s12192-020-01130-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4797: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article ; Online: COVID-19 and heme oxygenase: novel insight into the disease and potential therapies.

    Hooper, Philip L

    Cell stress & chaperones

    2020  Volume 25, Issue 5, Page(s) 707–710

    Abstract: The COVID-19 pandemic needs therapies that are presently available and safe. We propose that subjects with metabolic syndrome, old age, and male gender have the greatest morbidity and mortality and have low stress proteins, in particular, low ... ...

    Abstract The COVID-19 pandemic needs therapies that are presently available and safe. We propose that subjects with metabolic syndrome, old age, and male gender have the greatest morbidity and mortality and have low stress proteins, in particular, low intracellular heme oxygenase (HO-1), making them particularly vulnerable to the disease. Additionally, COVID-19's heme reduction may contribute to even lower HO-1. Low-grade inflammation associated with these risk factors contributes to triggering a cytokine storm that spreads to multi-organ failure and near death. The high mortality of those treated with ventilator assistance may partially be explained by ventilator-induced inflammation. The cytoprotective and anti-inflammatory properties of HO-1 can limit the infection's damage. A paradox of COVID-19 hospital admissions data suggests that fewer cigarette-smokers are admitted compared with non-smokers in the general population. This unexpected observation may result from smoke induction of HO-1. Therapies with anti-viral properties that raise HO-1 include certain anesthetics (sevoflurane or isoflurane), hemin, estrogen, statins, curcumin, resveratrol, and melatonin. Controlled trials of these HO-1 inducers should be done in order to prevent or treat COVID-19 disease.
    MeSH term(s) Age Factors ; Animals ; Antiviral Agents/therapeutic use ; COVID-19 ; Coronavirus Infections/epidemiology ; Coronavirus Infections/immunology ; Coronavirus Infections/therapy ; Cytokines/immunology ; Heat-Shock Proteins/immunology ; Heme Oxygenase-1/physiology ; Humans ; Inflammation/immunology ; Male ; Pandemics ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/immunology ; Pneumonia, Viral/therapy ; Sex Factors ; Smokers
    Chemical Substances Antiviral Agents ; Cytokines ; Heat-Shock Proteins ; HMOX1 protein, human (EC 1.14.14.18) ; Heme Oxygenase-1 (EC 1.14.14.18)
    Keywords covid19
    Language English
    Publishing date 2020-06-04
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 1362749-1
    ISSN 1466-1268 ; 1355-8145
    ISSN (online) 1466-1268
    ISSN 1355-8145
    DOI 10.1007/s12192-020-01126-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4797: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article: Correction to: COVID-19 and heme oxygenase: novel insight into the disease and potential therapies

    Hooper, Philip L

    Cell Stress Chaperones

    Abstract: In the original publication, one of the last paragraphs should have read as follows. ...

    Abstract In the original publication, one of the last paragraphs should have read as follows.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #642067
    Database COVID19

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  6. Article ; Online: Correction to

    Hooper, Philip L.

    Cell Stress and Chaperones

    COVID-19 and heme oxygenase: novel insight into the disease and potential therapies

    2020  Volume 25, Issue 5, Page(s) 711–711

    Keywords Cell Biology ; Biochemistry ; covid19
    Language English
    Publisher Springer Science and Business Media LLC
    Publishing country us
    Document type Article ; Online
    ZDB-ID 1362749-1
    ISSN 1466-1268 ; 1355-8145
    ISSN (online) 1466-1268
    ISSN 1355-8145
    DOI 10.1007/s12192-020-01130-z
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4797: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  7. Article ; Online: COVID-19 and heme oxygenase

    Hooper, Philip L.

    Cell Stress and Chaperones

    novel insight into the disease and potential therapies

    2020  Volume 25, Issue 5, Page(s) 707–710

    Keywords Cell Biology ; Biochemistry ; covid19
    Language English
    Publisher Springer Science and Business Media LLC
    Publishing country us
    Document type Article ; Online
    ZDB-ID 1362749-1
    ISSN 1466-1268 ; 1355-8145
    ISSN (online) 1466-1268
    ISSN 1355-8145
    DOI 10.1007/s12192-020-01126-9
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 4797: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  8. Article: COVID-19 and heme oxygenase: novel insight into the disease and potential therapies

    Hooper, Philip L

    Cell Stress Chaperones

    Abstract: The COVID-19 pandemic needs therapies that are presently available and safe. We propose that subjects with metabolic syndrome, old age, and male gender have the greatest morbidity and mortality and have low stress proteins, in particular, low ... ...

    Abstract The COVID-19 pandemic needs therapies that are presently available and safe. We propose that subjects with metabolic syndrome, old age, and male gender have the greatest morbidity and mortality and have low stress proteins, in particular, low intracellular heme oxygenase (HO-1), making them particularly vulnerable to the disease. Additionally, COVID-19's heme reduction may contribute to even lower HO-1. Low-grade inflammation associated with these risk factors contributes to triggering a cytokine storm that spreads to multi-organ failure and near death. The high mortality of those treated with ventilator assistance may partially be explained by ventilator-induced inflammation. The cytoprotective and anti-inflammatory properties of HO-1 can limit the infection's damage. A paradox of COVID-19 hospital admissions data suggests that fewer cigarette-smokers are admitted compared with non-smokers in the general population. This unexpected observation may result from smoke induction of HO-1. Therapies with anti-viral properties that raise HO-1 include certain anesthetics (sevoflurane or isoflurane), hemin, estrogen, statins, curcumin, resveratrol, and melatonin. Controlled trials of these HO-1 inducers should be done in order to prevent or treat COVID-19 disease.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #526840
    Database COVID19

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  9. Article: Induction of Heat Shock Proteins in the Therapy of Type 2 Diabetes and Metabolic Syndrome.

    Hooper, Philip L

    EBioMedicine

    2014  Volume 1, Issue 1, Page(s) 14–15

    Language English
    Publishing date 2014-11
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2851331-9
    ISSN 2352-3964 ; 2352-3964
    ISSN (online) 2352-3964
    ISSN 2352-3964
    DOI 10.1016/j.ebiom.2014.11.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 7090: Show issues Location:
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    ab Jg. 2022: Lesesaal (EG)

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  10. Article ; Online: Carbonic Anhydrase Inhibitors for the Treatment of High-Altitude Hypoxemia.

    Hooper, Philip L / Swenson, Erik R / Johnson, Richard J

    The American journal of medicine

    2019  Volume 132, Issue 11, Page(s) e799–e800

    MeSH term(s) Aged ; Altitude Sickness/diagnosis ; Altitude Sickness/drug therapy ; Carbonic Anhydrase Inhibitors/therapeutic use ; Colorado ; Diagnosis, Differential ; Female ; Humans ; Oxygen Inhalation Therapy
    Chemical Substances Carbonic Anhydrase Inhibitors
    Language English
    Publishing date 2019-05-30
    Publishing country United States
    Document type Case Reports ; Letter
    ZDB-ID 80015-6
    ISSN 1555-7162 ; 1873-2178 ; 0002-9343 ; 1548-2766
    ISSN (online) 1555-7162 ; 1873-2178
    ISSN 0002-9343 ; 1548-2766
    DOI 10.1016/j.amjmed.2019.05.013
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Ua VI Zs.289: Show issues Location:
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