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  1. Book ; Thesis: Monozyten-Subtypen und ihre Funktionalität in Patienten mit ANCA-assoziierter Vaskulitis im Vergleich zu gesunden Kontrollen

    Schubert, Leon / Weigt, Jochen / Kielstein, Jan T.

    Eine Untersuchung anhand neuester Charakterisierungsmarker

    2020  

    Title variant antineutrophile-zytoplasmatische Antikörper
    Institution Otto-von-Guericke-Universität Magdeburg
    Author's details vorgelegt von Leon Schubert aus Berlin ; Gutachter: Jochen Weigt ; Jan Kielstein
    Keywords Vaskulitis ; Autoaggressionskrankheit ; Monozyt
    Subject Blutmakrophage ; Blutwanderzelle ; Monocyt ; Monozyten ; Monocyten ; Autoantikörperkrankheit ; Autoimmunkrankheit ; Autoimmunopathie ; Autoimmunerkrankung ; Gefäßentzündung ; Vasculitis ; Vascularitis ; Vaskulitiden ; Angiitis ; Systemische Vasculitis ; Vasculitides ; Angiitides
    Language German
    Size 87 Blätter, Illustrationen, Diagramme
    Publisher Otto-von-Guericke-Universität Magdeburg
    Publishing place Magdeburg
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Universität Magdeburg, 2021
    HBZ-ID HT021190763
    Database Catalogue ZB MED Medicine, Health

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  2. Book ; Thesis: Stationäre Akutdialyse mit dem citrathaltigen Dialysekonzentrat Citrasate®

    Petzinna, Jana / Busch, Martin / Gerth, Jens / Kielstein, Jan T.

    Sicherheit, Erfolgsrate und Potential zur Einsparung von Antikoagulantien

    2023  

    Institution Friedrich-Schiller-Universität Jena
    Author's details von Jana Petzinna
    Keywords Hämodialyse ; Blutgerinnungshemmung
    Subject Blutantikoagulation ; Blutgerinnung ; Antikoagulation ; Gerinnungshemmung ; Blutdialyse ; Blutwäsche
    Language German
    Size 89 Blätter, Diagramme, 29,5 cm
    Publishing place Jena
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Friedrich-Schiller-Universität Jena, 2023
    Note Tag der Verteidigung: 14.03.2023
    HBZ-ID HT030654287
    Database Catalogue ZB MED Medicine, Health

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  3. Book ; Thesis: Indikation, Patientencharakteristika, Verfahrensmerkmale und Nebenwirkungen des Plasmaaustausches

    Asper, Firas / Kielstein, Jan T.

    retrospektive Auswertung von 912 Behandlungen

    2019  

    Institution Medizinische Hochschule Hannover
    Klinik für Nieren- und Hochdruckerkrankungen
    Author's details vorgelegt von Firas Asper aus Wolfsburg ; aus der Klinik für Nieren- und Hochdruckerkrankungen der Medizinischen Hochschule Hannover ; Betreuer/in der Arbeit: Prof. Dr. med. Jan Kielstein
    Language German ; English
    Size 37 Blätter, Illustrationen, Diagramme
    Publishing place Hannover
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Dissertation, Medizinische Hochschule Hannover, 2020
    Note Text auf Deutsch, Sonderabdruck auf Englisch ; Enthält 1 Sonderabdruck aus: BMC Nephrology ; 19:12.2018. 7 Seiten
    HBZ-ID HT020374463
    Database Catalogue ZB MED Medicine, Health

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  4. Article: Hämoperfusion und Plasmapherese auf der Intensivstation: A bridge over troubled water?

    Kielstein, Jan T

    Wiener klinisches Magazin : Beilage zur Wiener klinischen Wochenschrift

    2023  , Page(s) 1–6

    Abstract: In addition to kidney replacement procedures, several other extracorporeal procedures are employed in the intensive care unit. Hemoperfusion with activated charcoal was the predominant treatment used for removal of toxins from the 1970s until the ... ...

    Title translation Hemoperfusion and plasmapheresis in the intensive care unit.
    Abstract In addition to kidney replacement procedures, several other extracorporeal procedures are employed in the intensive care unit. Hemoperfusion with activated charcoal was the predominant treatment used for removal of toxins from the 1970s until the millennium. Nowadays, this treatment does no longer play a clinically meaningful role as even strongly protein-bound toxins can be removed by effective dialysis procedures in case poisoning. The concept of a cytokine adsorber was introduced 10 years ago, which is directed towards withstanding the cytokine storm. Despite negative data from prospective randomized controlled studies, its use is steadily increasing in Germany. A totally different treatment concept is the biomimetic pathogen adsorber, which removes bacteria, viruses and fungi from the bloodstream by binding to immobilized heparin. Whether this rapid reduction of the pathogen load translates into an improvement of clinically relevant endpoints is unclear, as prospective randomized controlled studies are lacking. For the early hours of septic shock a very old procedure, plasmapheresis, has recently regained interest. The results of two large randomized controlled studies in this setting from Europe and Canada will become available in 2025/2026. The rationale to use plasma exchange in early sepsis is that this procedure not only removes cytokines but also replenishes reduced levels of protective factors, such as angiopoietin‑1, a disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13 (ADAMTS-13) and protein C, if fresh plasma is used as exchange fluid. All afore mentioned procedures do not only have a different mode of action but are also used at seperate time points of bloodstream infections and/or sepsis.
    Language German
    Publishing date 2023-03-01
    Publishing country Austria
    Document type English Abstract ; Journal Article ; Review
    ZDB-ID 2230871-4
    ISSN 1613-7817 ; 1869-1757 ; 1434-6869
    ISSN (online) 1613-7817
    ISSN 1869-1757 ; 1434-6869
    DOI 10.1007/s00740-023-00486-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: The authors reply.

    Zarbock, Alexander / Kielstein, Jan T

    Critical care medicine

    2022  Volume 50, Issue 9, Page(s) e740–e741

    Language English
    Publishing date 2022-08-15
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 197890-1
    ISSN 1530-0293 ; 0090-3493
    ISSN (online) 1530-0293
    ISSN 0090-3493
    DOI 10.1097/CCM.0000000000005605
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Is This the Beginning of the End of Cytokine Adsorption?

    Kielstein, Jan T / Zarbock, Alexander

    Critical care medicine

    2022  Volume 50, Issue 6, Page(s) 1026–1029

    MeSH term(s) Adsorption ; Cytokines ; Extracorporeal Membrane Oxygenation
    Chemical Substances Cytokines
    Language English
    Publishing date 2022-02-21
    Publishing country United States
    Document type Editorial ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 197890-1
    ISSN 1530-0293 ; 0090-3493
    ISSN (online) 1530-0293
    ISSN 0090-3493
    DOI 10.1097/CCM.0000000000005509
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Artificial hallucination: GPT on LSD?

    Beutel, Gernot / Geerits, Eline / Kielstein, Jan T

    Critical care (London, England)

    2023  Volume 27, Issue 1, Page(s) 148

    MeSH term(s) Humans ; Artificial Intelligence ; Hallucinations/chemically induced
    Language English
    Publishing date 2023-04-18
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 2041406-7
    ISSN 1466-609X ; 1364-8535
    ISSN (online) 1466-609X
    ISSN 1364-8535
    DOI 10.1186/s13054-023-04425-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Book ; Online ; Thesis: Klinische und anatomische Gründe, die gegen die Verwendung einer 70 mm Seldinger Nadel bei der Punktion der Vena jugularis interna sprechen

    Wenzel, Clara [Verfasser] / Kielstein, Jan T. [Akademischer Betreuer]

    2024  

    Author's details Clara Wenzel ; Akademischer Betreuer: Jan T. Kielstein ; Klinik für Nieren- und Hochdruckerkrankungen
    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language German
    Publisher Bibliothek der Medizinischen Hochschule Hannover
    Publishing place Hannover
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

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  9. Book ; Thesis: Proteoglycans

    Kielstein, Jan T.

    biomechanical and physicochemical properties of Atlantic hagfish (Myxine glutinosa) notochord

    1998  

    Author's details vorgelegt von Jan T. Kielstein
    Language English
    Size 98 Bl. : Ill., graph. Darst.
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Hannover, Med. Hochsch., Diss., 1999
    HBZ-ID HT012822387
    Database Catalogue ZB MED Medicine, Health

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  10. Article ; Online: Letter to the editor concerning the case report "Successful treatment of severe quetiapine intoxication with CytoSorb hemoadsorption".

    Kielstein, Jan T / Schmidt, Julius J / Ghannoum, Marc

    Journal of clinical pharmacy and therapeutics

    2022  Volume 47, Issue 9, Page(s) 1493–1494

    MeSH term(s) Cytokines ; Humans ; Quetiapine Fumarate ; Shock, Septic
    Chemical Substances Cytokines ; Quetiapine Fumarate (2S3PL1B6UJ)
    Language English
    Publishing date 2022-08-02
    Publishing country England
    Document type Case Reports ; Letter ; Comment
    ZDB-ID 639006-7
    ISSN 1365-2710 ; 0269-4727
    ISSN (online) 1365-2710
    ISSN 0269-4727
    DOI 10.1111/jcpt.13749
    Database MEDical Literature Analysis and Retrieval System OnLINE

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