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  1. Article: Hemophagocytic Lymphohistiocytosis: A Diagnostic Conundrum.

    Grzybowski, Brittany / Vishwanath, Vijay A

    Journal of pediatric neurosciences

    2016  Volume 12, Issue 1, Page(s) 55–60

    Abstract: Hemophagocytic lymphohistiocytosis (HLH) is a syndrome of excessive immune activation causing widespread inflammation and tissue destruction leading to multi-organ dysfunction and failure. Making the diagnosis of HLH could be quite challenging due to the ...

    Abstract Hemophagocytic lymphohistiocytosis (HLH) is a syndrome of excessive immune activation causing widespread inflammation and tissue destruction leading to multi-organ dysfunction and failure. Making the diagnosis of HLH could be quite challenging due to the broad range of presenting symptoms and their lack of specificity. After ruling out considerations for differential diagnoses, recognizing the most common presenting signs and symptoms of HLH, including neurologic dysfunction, and having a high clinical suspicion for HLH in the setting of inflammatory/demyelinating diseases are important for prompt diagnosis and treatment.
    Language English
    Publishing date 2016-09-16
    Publishing country India
    Document type Case Reports
    ISSN 1817-1745
    ISSN 1817-1745
    DOI 10.4103/jpn.JPN_140_16
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Hemophagocytic lymphohistiocytosis

    Brittany Grzybowski / Vijay A Vishwanath

    Journal of Pediatric Neurosciences, Vol 12, Iss 1, Pp 55-

    A diagnostic conundrum

    2017  Volume 60

    Abstract: Hemophagocytic lymphohistiocytosis (HLH) is a syndrome of excessive immune activation causing widespread inflammation and tissue destruction leading to multi-organ dysfunction and failure. Making the diagnosis of HLH could be quite challenging due to the ...

    Abstract Hemophagocytic lymphohistiocytosis (HLH) is a syndrome of excessive immune activation causing widespread inflammation and tissue destruction leading to multi-organ dysfunction and failure. Making the diagnosis of HLH could be quite challenging due to the broad range of presenting symptoms and their lack of specificity. After ruling out considerations for differential diagnoses, recognizing the most common presenting signs and symptoms of HLH, including neurologic dysfunction, and having a high clinical suspicion for HLH in the setting of inflammatory/demyelinating diseases are important for prompt diagnosis and treatment.
    Keywords Acute disseminated encephalomyelitis ; encephalopathy ; familial hemophagocytic lymphohistiocytosis ; hemophagocytic lymphohistiocytosis ; seizures ; Pediatrics ; RJ1-570 ; Medicine ; R ; Neurosciences. Biological psychiatry. Neuropsychiatry ; RC321-571 ; Internal medicine ; RC31-1245
    Language English
    Publishing date 2017-01-01T00:00:00Z
    Publisher Medknow Publications
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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