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  1. Article: Why networks?

    Gaehtgens, P

    International journal of microcirculation, clinical and experimental

    1992  Volume 11, Issue 2, Page(s) 123–132

    Abstract: The development of the network concept is prompted by the accumulated quantitative disagreement between the behaviour of single microvessels and the changes of total tissue blood flow, as well as by the ubiquitous flow heterogeneity. It is further driven ...

    Abstract The development of the network concept is prompted by the accumulated quantitative disagreement between the behaviour of single microvessels and the changes of total tissue blood flow, as well as by the ubiquitous flow heterogeneity. It is further driven by the difficulty to attach function-oriented nomenclatures to structural elements of the terminal vascular bed. So far, the efforts of mathematical network modelling have led to a reasonably coherent analysis of microcirculatory hemodynamics from available data on network geometry and blood rheology. These efforts have shown that complete data sets are important because of the non-symmetric architecture of most networks. Due to its effect on exchange efficiency, the relationship between network heterogeneity and total flow regulation remains the currently most relevant physiological problem. So far, the hypothesis of flow heterogeneity being controlled through intra-network communication and consecutive readjustment of flow and flux dispersions is intriguing, but speculative.
    MeSH term(s) Animals ; Hemodynamics/physiology ; Microcirculation/anatomy & histology ; Microcirculation/physiology ; Models, Cardiovascular
    Language English
    Publishing date 1992-05
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 603169-9
    ISSN 0167-6865
    ISSN 0167-6865
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1747: Show issues Location:
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  2. Book: Untersuchungen über die Beziehung zwischen Durchblutung und Stoffaustausch im Skeletmuskel unter Berücksichtigung der funktionellen Shunt-Durchblutung

    Gaehtgens, Peter / Benner, Klaus-Ulrich / Schickendantz, Sabine

    (Forschungsbericht des Landes Nordrhein-Westfalen ; 2703 : Fachgruppe Medizin)

    1977  

    Title variant Untersuchungen über die Beziehung zwischen Durchblutung und Stoffaustausch im Skelettmuskel unter Berücksichtigung der funktionellen Shunt-Durchblutung
    Author's details Peter Gaehtgens ; Klaus-Ulrich Benner ; Sabine Schickendantz
    Series title Forschungsbericht des Landes Nordrhein-Westfalen ; 2703 : Fachgruppe Medizin
    Forschungsberichte des Landes Nordrhein-Westfalen
    Collection Forschungsberichte des Landes Nordrhein-Westfalen
    Keywords BIOLOGICAL TRANSPORT ; MICROCIRCULATION ; MUSCLES / PHYSIOLOGY ; Shunt ; Durchblutung ; Skelettmuskel
    Subject Nebenschluss
    Language German
    Size 24 S. : graph. Darst.
    Publisher Westdt. Verl
    Publishing place Opladen
    Publishing country Germany
    Document type Book
    HBZ-ID HT000924623
    ISBN 3-531-02703-4 ; 978-3-531-02703-6
    Database Catalogue ZB MED Medicine, Health

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    Shelf markLoan statusLocation
    1978 A 1922 order for loan Magazin

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  3. Article: Heterogeneity of capillary perfusion.

    Gaehtgens, P

    Blood vessels

    1991  Volume 28, Issue 1-3, Page(s) 197–200

    Abstract: Heterogeneity represents a general feature of capillary networks. All of the parameters which describe hemodynamic, geometric or functional aspects of such networks exhibit considerable spatial dispersion. This is to some extent the result of the ... ...

    Abstract Heterogeneity represents a general feature of capillary networks. All of the parameters which describe hemodynamic, geometric or functional aspects of such networks exhibit considerable spatial dispersion. This is to some extent the result of the morphological and topological design of the network, reinforced by the nonhomogeneous nature of the flowing blood. Temporal dispersions are introduced by smooth muscle activity, which may be rhythmic or just oscillatory, but also by the passage of white cells causing transient perturbations. The functional relevance of perfusion heterogeneity follows from its effect on exchange efficiency. While evidence for the existence of physiological control mechanisms of heterogeneity is uncertain, intranetwork communication between upstream and downstream vessel segments appears to support the adaptation of supply to demand under physiological conditions.
    MeSH term(s) Animals ; Capillaries/anatomy & histology ; Capillaries/physiology ; Erythrocytes/cytology ; Erythrocytes/physiology ; Hemodynamics ; Leukocytes/cytology ; Leukocytes/physiology
    Language English
    Publishing date 1991
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 125104-1
    ISSN 0303-6847 ; 0302-2765
    ISSN 0303-6847 ; 0302-2765
    DOI 10.1159/000158862
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Rheological properties and blood flow behavior in tube flow and vascular networks.

    Gaehtgens, P

    Monographs on atherosclerosis

    1990  Volume 15, Page(s) 160–169

    Abstract: Improvement of hemorheological methodology in recent years has led to increased knowledge about rheological properties of blood. By contrast, however, the concepts underlying interpretation of rheological behavior in the cardiovascular system are less ... ...

    Abstract Improvement of hemorheological methodology in recent years has led to increased knowledge about rheological properties of blood. By contrast, however, the concepts underlying interpretation of rheological behavior in the cardiovascular system are less well developed. Recent rheological measurements during blood flow in small tubes show that predictions of microcirculatory hemodynamics on the basis of viscometric measurements remain uncertain. The rheological consequence of cell sedimentation as well as flow fractionation effects at microvessel bifurcations need to be taken into account.
    MeSH term(s) Blood Vessels/physiology ; Blood Viscosity ; Hemodynamics/physiology ; Humans ; Models, Cardiovascular ; Rheology ; Stress, Mechanical
    Language English
    Publishing date 1990
    Publishing country Switzerland
    Document type Journal Article ; Review
    ISSN 0077-099X
    ISSN 0077-099X
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  5. Article: Rheological mechanisms contributing to low flow hypoxia.

    Gaehtgens, P

    Biomedica biochimica acta

    1989  Volume 48, Issue 2-3, Page(s) S36–9

    MeSH term(s) Blood Circulation ; Blood Viscosity ; Hematocrit ; Humans ; Hypoxia/blood ; Hypoxia/etiology ; Hypoxia/physiopathology ; Models, Theoretical ; Rheology
    Language English
    Publishing date 1989
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 283559-9
    ISSN 0232-766X
    ISSN 0232-766X
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Strukturplanung: Das Ganze ist mehr als die Summe seiner Teile

    Gaehtgens P

    FU-N

    1996  , Issue 1, Page(s) 33–34

    Abstract: Durch das UniMedGesetz wurde die Berliner Universitaetsmedizin zum 1. April 1995 neu geordnet; an der Freien Universitaet wurden die grundlagenmedizinischen und klinischen Disziplinen zu dem neuen Fachbereich Humanmedizin (UKBF) zusammengefuehrt. Die ... ...

    Abstract Durch das UniMedGesetz wurde die Berliner Universitaetsmedizin zum 1. April 1995 neu geordnet; an der Freien Universitaet wurden die grundlagenmedizinischen und klinischen Disziplinen zu dem neuen Fachbereich Humanmedizin (UKBF) zusammengefuehrt. Die Fakultaeten bzw. Klinika der Freien und Humboldt-Universitaet erhielten gleichzeitig die Aufgabe, durch Bildung von Schwerpunkten jeweils spezifische Leistungsprofile zu entwickeln. ( Nachdruck)
    Keywords Ärztlicher Dienst ; Ausbildung ; Neuordnung ; Universitätsklinikum ; Lehrplan ; Forschung ; Spezialisierung ; Kooperation ; Personaleinsatz ; Gesetz und Verordnung ; Deutschland ; Berlin
    Language German
    Size Umfang: einige Aspekte ; Tiefe und Qualität: instruktiv
    Publishing place Berlin
    Document type Article
    ZDB-ID 2142149-3
    ISSN 0944-0585
    ISSN 0944-0585
    Database Health Care Literature Information Network (HECLINET)

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  7. Article: Strukturplanung: Das Ganze ist mehr als die Summe seiner Teile

    Gaehtgens P

    FU-N

    1996  , Issue 1, Page(s) 33–34

    Abstract: Durch das UniMedGesetz wurde die Berliner Universitaetsmedizin zum 1. April 1995 neu geordnet; an der Freien Universitaet wurden die grundlagenmedizinischen und klinischen Disziplinen zu dem neuen Fachbereich Humanmedizin (UKBF) zusammengefuehrt. Die ... ...

    Abstract Durch das UniMedGesetz wurde die Berliner Universitaetsmedizin zum 1. April 1995 neu geordnet; an der Freien Universitaet wurden die grundlagenmedizinischen und klinischen Disziplinen zu dem neuen Fachbereich Humanmedizin (UKBF) zusammengefuehrt. Die Fakultaeten bzw. Klinika der Freien und Humboldt-Universitaet erhielten gleichzeitig die Aufgabe, durch Bildung von Schwerpunkten jeweils spezifische Leistungsprofile zu entwickeln. ( Nachdruck)
    Keywords Ärztlicher Dienst ; Ausbildung ; Neuordnung ; Universitätsklinikum ; Lehrplan ; Forschung ; Spezialisierung ; Kooperation ; Personaleinsatz ; Gesetz und Verordnung ; Deutschland ; Berlin
    Language German
    Size Umfang: einige Aspekte ; Tiefe und Qualität: instruktiv
    Publishing place Berlin
    Document type Article
    ZDB-ID 2142149-3
    ISSN 0944-0585
    ISSN 0944-0585
    Database bibnet.org

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  8. Article: Tube flow of human blood at near zero shear.

    Gaehtgens, P

    Biorheology

    1987  Volume 24, Issue 4, Page(s) 367–376

    Abstract: Pressure-velocity relations were obtained in vertical and horizontal glass tubes (I.D. 26 to 83 micron) perfused with normal human blood at feed hematocrits between 0.25 and 0.65. Perfusion pressures used corresponded to wall shear stresses up to 0.27 ... ...

    Abstract Pressure-velocity relations were obtained in vertical and horizontal glass tubes (I.D. 26 to 83 micron) perfused with normal human blood at feed hematocrits between 0.25 and 0.65. Perfusion pressures used corresponded to wall shear stresses up to 0.27 dyn cm-2. Red cell velocity measurements were made both immediately following implementation of perfusion pressure (with red cells still disaggregated) and in a steady state situation (with red cells aggregated). Analysis of the slopes of the linear relations between perfusion pressure and velocity showed apparent viscosity to decrease with the manifestation of red cell aggregation. In horizontal tubes, sedimentation and aggregation occurred simultaneously, and apparent viscosity increased due to axial asymmetry of cell concentration. Evidence for a yield shear stress (flow stagnation at positive driving pressure) was not observed.
    MeSH term(s) Blood Flow Velocity ; Blood Pressure ; Blood Viscosity ; Erythrocyte Aggregation ; Erythrocytes/physiology ; Hematocrit ; Humans ; Perfusion ; Rheology
    Language English
    Publishing date 1987
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 82015-5
    ISSN 1878-5034 ; 0006-355X
    ISSN (online) 1878-5034
    ISSN 0006-355X
    DOI 10.3233/bir-1987-24402
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: FU 2000 : Katastrophe oder Chance?

    Gaehtgens P

    FU-N

    1995  , Issue 1, Page(s) 7

    Abstract: Das Gesetz zur Neuordnung der Universitaetsmedizin (UniMedG) hat die FU-Medizin erheblich dezimiert: Das UKRV geht am 1.April zur Humboldt-Universitaet, und die FU-Vorklinik wird auf ein Drittel reduziert. ...

    Abstract Das Gesetz zur Neuordnung der Universitaetsmedizin (UniMedG) hat die FU-Medizin erheblich dezimiert: Das UKRV geht am 1.April zur Humboldt-Universitaet, und die FU-Vorklinik wird auf ein Drittel reduziert.
    Keywords Universitätsklinikum ; Neuordnung ; Krankenhauspolitik ; Deutschland ; Berlin
    Language German
    Size Umfang: einige Aspekte ; Tiefe und Qualität: allgemein gehalten
    Publishing place Berlin
    Document type Article
    ZDB-ID 2142149-3
    ISSN 0944-0585
    ISSN 0944-0585
    Database Health Care Literature Information Network (HECLINET)

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  10. Article: FU 2000 : Katastrophe oder Chance?

    Gaehtgens P

    FU-N

    1995  , Issue 1, Page(s) 7

    Abstract: Das Gesetz zur Neuordnung der Universitaetsmedizin (UniMedG) hat die FU-Medizin erheblich dezimiert: Das UKRV geht am 1.April zur Humboldt-Universitaet, und die FU-Vorklinik wird auf ein Drittel reduziert. ...

    Abstract Das Gesetz zur Neuordnung der Universitaetsmedizin (UniMedG) hat die FU-Medizin erheblich dezimiert: Das UKRV geht am 1.April zur Humboldt-Universitaet, und die FU-Vorklinik wird auf ein Drittel reduziert.
    Keywords Universitätsklinikum ; Neuordnung ; Krankenhauspolitik ; Deutschland ; Berlin
    Language German
    Size Umfang: einige Aspekte ; Tiefe und Qualität: allgemein gehalten
    Publishing place Berlin
    Document type Article
    ZDB-ID 2142149-3
    ISSN 0944-0585
    ISSN 0944-0585
    Database bibnet.org

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