LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 652

Search options

  1. Article ; Online: Du coronavirus au corpus de la planification d’urgence…

    Thiry, Aline / Hendrickx, Kim / Ozer, Pierre / Brunet, Sébastien / Fallon, Catherine

    Du coronavirus au corpus de la planification d’urgence… Le Soir , p. 77.Bruxelles, BelgiumRossel. (2020).

    2020  

    Abstract: La crise sanitaire actuelle nous a surpris à plusieurs égards. Elle inspire en tout cas une série de réflexions. Comme celles de ces cinq universitaires. [Chapeau du journal Le Soir] ...

    Abstract La crise sanitaire actuelle nous a surpris à plusieurs égards. Elle inspire en tout cas une série de réflexions. Comme celles de ces cinq universitaires. [Chapeau du journal Le Soir]
    Keywords Covid-19 ; Gestion de crise ; Belgique ; Law ; criminology & political science :: Multidisciplinary ; general & others ; Droit ; criminologie & sciences politiques :: Multidisciplinaire ; généralités & autres ; criminology & political science :: Political science ; public administration & international relations ; criminologie & sciences politiques :: Sciences politiques ; administration publique & relations internationales ; covid19
    Language French
    Publishing date 2020-04-02
    Publishing country be
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    More links

    Kategorien

  2. Article: Epidémie nosocomiale à norovirus : à propos d’une expérience hospitalière.

    Huynen, P / Mauroy, A / Lambert, N / De Mol, P / Thiry, E / Melin, P

    Revue medicale de Liege

    2019  Volume 74, Issue 2, Page(s) 86–89

    Abstract: Human noroviruses (NoV) are the main pathogenic agents worldwide responsible for viral sporadic and epidemic gastroenteritis worldwide. A gastroenteritis outbreak broke out in patients hospitalized in several wards located in two different floors of a ... ...

    Title translation Norovirus nosocomial outbreak : an hospital experience.
    Abstract Human noroviruses (NoV) are the main pathogenic agents worldwide responsible for viral sporadic and epidemic gastroenteritis worldwide. A gastroenteritis outbreak broke out in patients hospitalized in several wards located in two different floors of a hospital in Liege, Belgium. The objective was to determine whether a same NoV strain would be involved in the two different floors, and to explore how this outbreak would have spread from a floor to the other. Stool samples from patients and healthcare workers were collected, as well as data from medical files. NoV detection, quantification and characterization were performed using molecular biology methods. A same NoV strain, from genotype GII.4, was detected in two patients hospitalized on the two different floors. This finding allowed to conclude that a same outbreak spread in the two floors, probably due to movements of common healthcare workers. A rapid NoV detection during outbreak is important in the aim to rapidly implement hygiene measures to limit the size of the outbreak.
    MeSH term(s) Belgium ; Caliciviridae Infections/epidemiology ; Cross Infection ; Disease Outbreaks ; Genotype ; Hospitals ; Humans ; Norovirus/isolation & purification ; Phylogeny ; Sequence Analysis, DNA
    Language French
    Publishing date 2019-02-21
    Publishing country Belgium
    Document type Case Reports
    ZDB-ID 414001-1
    ISSN 0370-629X ; 0035-3663
    ISSN 0370-629X ; 0035-3663
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  3. Article ; Online: Auton’al 60 : programme de prévention de la perte d’autonomie des seniors de l’Oise avec des ateliers multithématiques (2019–2021)

    Thiry, C. M. T. / Breil, B. / Branchu, J. Thomassin / Depeint, F. / Pouillart, P. R. / Younes, H. / Orthez, C. Delayre- / Vincent, V. / Foissy, C. Buche / Illner, A. K.

    Nutrition clinique et métabolisme. 2023 May, v. 37, no. 2, p. e53

    2023  

    Abstract: ... que le vieillissement est corrélé à l’augmentation des maladies chroniques et donc à la perte d’autonomie ... environnement et de l’entourage social et psychologique. Les facteurs de risque sont multiples : manque d’accès ... à une alimentation équilibrée, d’activité physique ou de lien social. Suite à la première édition du programme Auton ...

    Abstract En 2020, 20,5 % de la population française ont plus de 65 ans et, en 2040, ils seront plus de 25,0 %. Dans l’Oise, les plus de 65 ans passeront de 14,3 % (2013) à 25,4 % (2050). Des études montrent que le vieillissement est corrélé à l’augmentation des maladies chroniques et donc à la perte d’autonomie. Cette autonomie varie selon les individus, elle ne dépend pas seulement de l’état de santé, mais aussi de l’environnement et de l’entourage social et psychologique. Les facteurs de risque sont multiples : manque d’accès à une alimentation équilibrée, d’activité physique ou de lien social. Suite à la première édition du programme Auton’Al 60 en 2018, l’objectif de cette seconde édition d’Auton’Al 60 sur 3 ans est de prévenir la perte d’autonomie des personnes âgées de plus de 60 ans, en les sensibilisant grâce à des actions autour de l’alimentation, l’activité physique adaptée et la santé mentale. Ce programme de recherche-action est à destination des 60 ans et plus, hommes et femmes, avec un GIR (groupe iso-ressources) 5 ou 6, de l’Oise, avec l’objectif d’atteindre 150 personnes. Chaque année (2019–2021), le recrutement multisite était organisé grâce à la distribution de flyers papiers et affiches. L’inscription selon les critères d’inclusion se faisait par téléphone, par mail ou en direct. L’objectif était de toucher 50 personnes par an pour participer à 3 ateliers de prévention interactifs et multithématiques (ex : perception sensorielle et activité physique adaptée). Les ateliers se déroulaient à UniLaSalle Beauvais et dans des associations ou centres sociaux ruraux de l’Oise. L’évaluation comprenait des questionnaires autodéclaratifs avant les ateliers (T0) et 1 mois après (T1) sur leurs modes de vie, habitudes alimentaires, littératie alimentaire et satisfaction globale. Une campagne itinérante visant 200 personnes était organisée du 14 au 26 juin 2021 dans 12 villes de l’Oise pour toucher les personnes en situation d’isolement. Des jeux d’éducation nutritionnelle, des ateliers culinaires, du dépistage de diabète et des entretiens diététiques étaient proposés dans des bus événementiels. Des stands d’associations et d’organismes locaux étaient également présents. Les 42 ateliers réalisés ont sensibilisé 135 personnes (taux de recrutement [90 %]). Selon le questionnaire T0, la population recrutée correspond bien aux critères d’inclusion et fait partie des personnes fragiles. Au total, 76,3 % ont 65 ans et plus (70,4, ±7,3), majoritairement des femmes (85,2 %), des personnes vivant seules (52,6 %), 14,4 % ont des aides ponctuelles ou sont en perte d’autonomie. Seulement 13,3 % de la population ont déclaré une absence de maladie chronique et 25,6 % ont un indice de masse corporelle (IMC) normal. La prévalence de l’obésité est de 25,6 %. Le taux de fidélisation montre que 83,7 % ont participé à au moins 2 ateliers sur les 3 proposés. Les réponses au questionnaire T1 montrent que 63,0 % déclarent avoir changé leurs habitudes alimentaires ; 34,6 % ont réduit leur consommation de sucre, 32,1 % de sel, et 22,2 % de matières grasses. La campagne itinérante a pu sensibiliser plus de 200 personnes. Au total, 99,1 % des bénéficiaires interrogés (n=113) ont été satisfaits d’y participer (dont 79,6 % sont très satisfaits) et 97,2 % souhaitent faire d’autres ateliers. Ce programme a sensibilisé plus de 300 personnes à la perte d’autonomie. Les taux de satisfaction et de fidélisation confirment que l’ensemble du concept de cette recherche-action est adapté à la cible et semble initier des changements de comportements alimentaires et des habitudes de vie. Il a aussi permis de réunir de nombreux partenaires (associations, centres sociaux ruraux, des professionnels divers (sport, gym douce, santé…), des municipalités, etc. Deux conférences avec des experts ont été proposées aux bénéficiaires pour renforcer le message et créer du lien social. La souplesse du concept a permis de continuer le programme malgré la pandémie de COVID-19.
    Keywords COVID-19 infection ; nutrition ; questionnaires ; sports
    Language English
    Dates of publication 2023-05
    Size p. e53
    Publishing place Elsevier Masson SAS
    Document type Article ; Online
    ZDB-ID 1131758-9
    ISSN 0985-0562
    ISSN 0985-0562
    DOI 10.1016/j.nupar.2023.03.095
    Database NAL-Catalogue (AGRICOLA)

    More links

    Kategorien

  4. Book ; Online: Planification d’urgence et gestion de crise sanitaire. La Belgique face à la pandémie de Covid-19

    Fallon, Catherine / Thiry, Aline / Brunet, Sébastien

    Courrier hebdomadaire du CRISP, n 2453-2454, 8, 2020-07-06, pp.5-68

    2020  

    Keywords covid19
    Language French
    Publishing country fr
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    More links

    Kategorien

  5. Article ; Online: Planification d’urgence et gestion de crise sanitaire. La Belgique face à la pandémie de Covid-19 ; Emergency planning and crisis management. Belgium facing the Covid Pandemics

    Fallon, Catherine / Thiry, Aline / Brunet, Sébastien

    Planification d’urgence et gestion de crise sanitaire. La Belgique face à la pandémie de Covid-19. Courrier Hebdomadaire du CRISP, 2453-2454 .Bruxelles, BelgiumCentre de Recherche et d'Information Socio-Politiques (CRISP). (2020).

    2020  

    Abstract: ... d’urgence pour es interroger à la lumière du concept de « société du risque » Il présente ainsi la ... planification d’urgence, puis détaille les aspects institutionnels spécifiques propres à cette gestion de crise ...

    Abstract l'article met en perspective les dispositifs contemporains de gestion de crise et de planification d’urgence pour es interroger à la lumière du concept de « société du risque » Il présente ainsi la planification d’urgence, puis détaille les aspects institutionnels spécifiques propres à cette gestion de crise sanitaire, plus particulièrement au cours des premiers mois de 2020. Dans un second temps, l’étude s’attache aux limites de ce même dispositif de planification et de surveillance.

    the article puts into perspective contemporary crisis management systems and emergency planning to question them in light of the concept of "society of risk "He presents emergency planning, then details the aspects specific institutions specific to this health crisis management, more particularly in the first months of 2020. Secondly, the study focuses on the limits of this same planning and monitoring system.

    Peer reviewed
    Keywords COVID-19 ; Emergency Planning ; crisis management ; Law ; criminology & political science :: Political science ; public administration & international relations ; Droit ; criminologie & sciences politiques :: Sciences politiques ; administration publique & relations internationales ; covid19
    Language French
    Publishing country be
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    More links

    Kategorien

  6. Article ; Online: “How do I get From Here to There?” An Examination of Ph.D. Science Students’ Career Preparation and Decision Making

    Heather Thiry / Sandra L Laursen / Heidi G. Loshbaugh

    International Journal of Doctoral Studies, Vol 10, Pp 237-

    2015  Volume 256

    Abstract: Drawing on developmental networks theory, this qualitative research study explores the professional preparation and career decision-making processes of doctoral students in the sciences. The study is based on 95 semi-structured interviews with informants ...

    Abstract Drawing on developmental networks theory, this qualitative research study explores the professional preparation and career decision-making processes of doctoral students in the sciences. The study is based on 95 semi-structured interviews with informants at three research universities in the United States. Though many students were interested in non-academic career tracks, they were largely unaware of the breadth of their choices or how to best prepare for these careers. Unable to cultivate networks in non-academic careers, many students turned to peers to fill the career development gap. Due to their lack of knowledge about career options, among other factors, students often delayed selecting and preparing for careers until the end of their graduate studies. Implications for doctoral education practice are discussed.
    Keywords Ph.D. students ; career preparation ; decision-making processes ; doctoral students ; science students ; Technology ; T ; Technology (General) ; T1-995 ; Industrial engineering. Management engineering ; T55.4-60.8 ; Information technology ; T58.5-58.64 ; Bibliography. Library science. Information resources ; Z
    Language English
    Publishing date 2015-07-01T00:00:00Z
    Publisher Informing Science Institute
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    More links

    Kategorien

  7. Article: Characterization of caprine herpesvirus 1 glycoprotein D gene and its translation product.

    Keuser, Véronique / Detry, Bruno / Thiry, Julien / de Fays, Katalin / Schynts, Frédéric / Pastoret, Paul-Pierre / Vanderplasschen, Alain / Thiry, Etienne

    Virus research

    2006  Volume 115, Issue 2, Page(s) 112–121

    Abstract: ... BoHV-1) which causes infectious bovine rhinotracheitis. Glycoprotein D (gD) mediates important ... other alphaherpesviruses. A relatively high homology was found between CpHV-1 and BoHV-1 glycoproteins D ...

    Abstract Caprine herpesvirus 1 (CpHV-1) is responsible of systemic infection in neonatal kids as well as abortion and fertility disorders in adult goats. This virus is closely related to bovine herpesvirus 1 (BoHV-1) which causes infectious bovine rhinotracheitis. Glycoprotein D (gD) mediates important functions in alphaherpesviruses and is also a main immunogen. The sequence of CpHV-1 gD gene and the biochemical properties of its translation product were analyzed and compared to those of BoHV-1 and other alphaherpesviruses. A relatively high homology was found between CpHV-1 and BoHV-1 glycoproteins D amino acid sequences (similarity of 68.8%). Moreover, six cysteine residues are conserved by CpHV-1 gD and the other studied alphaherpesviruses. CpHV-1 gD has a molecular mass similar to BoHV-1 gD and contains complex N-linked oligosaccharides. In contrast to the BoHV-1 gD, CpHV-1 gD is expressed as a late protein. In spite of the observed differences which could influence its biological functions, CpHV-1 gD shares most characteristics with other alphaherpesviruses and especially BoHV-1.
    MeSH term(s) Alphaherpesvirinae/chemistry ; Alphaherpesvirinae/genetics ; Amino Acid Sequence ; Animals ; Cattle ; Cell Line ; Conserved Sequence ; Cysteine/genetics ; DNA, Viral/chemistry ; DNA, Viral/genetics ; Gene Expression Regulation, Viral ; Glycoproteins/chemistry ; Glycoproteins/genetics ; Molecular Sequence Data ; Molecular Weight ; Oligosaccharides/analysis ; Oligosaccharides/chemistry ; Sequence Analysis, DNA ; Sequence Homology, Amino Acid ; Varicellovirus/chemistry ; Varicellovirus/genetics ; Viral Envelope Proteins/chemistry ; Viral Envelope Proteins/genetics
    Chemical Substances DNA, Viral ; Glycoproteins ; Oligosaccharides ; Viral Envelope Proteins ; Cysteine (K848JZ4886)
    Language English
    Publishing date 2006-02
    Publishing country Netherlands
    Document type Comparative Study ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 605780-9
    ISSN 1872-7492 ; 0168-1702
    ISSN (online) 1872-7492
    ISSN 0168-1702
    DOI 10.1016/j.virusres.2005.07.009
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  8. Article ; Online: CD8- dendritic cells and macrophages cross-present poly(D,L-lactate-co-glycolate) acid microsphere-encapsulated antigen in vivo.

    Schliehe, Christopher / Redaelli, Chiara / Engelhardt, Sabrina / Fehlings, Michael / Mueller, Marc / van Rooijen, Nico / Thiry, Marc / Hildner, Kai / Weller, Horst / Groettrup, Marcus

    Journal of immunology (Baltimore, Md. : 1950)

    2011  Volume 187, Issue 5, Page(s) 2112–2121

    Abstract: ... dendritic cells (DCs) as well as macrophages (MΦs) are able to efficiently endocytose poly(D,L-lactate-co ...

    Abstract The analysis of cell types involved in cross-priming of particulate Ag is essential to understand and improve immunotherapies using microparticles. In this study, we show that murine splenic dendritic cells (DCs) as well as macrophages (MΦs) are able to efficiently endocytose poly(D,L-lactate-co-glycolate) acid (PLGA) microspheres (MS) and to cross-present encapsulated Ags in the context of MHC class I molecules in vitro. A comparison of purified CD8(+) and CD8(-) DCs indicated that both DC subtypes are able to present OVA-derived epitopes on MHC class I and II in vitro. To determine the contribution of DCs and MΦs to cross-priming of PLGA MS in vivo, DCs were depleted in transgenic CD11c-DTR mice, and MΦs were depleted by clodronate liposomes in wild-type mice before immunizing mice with OVA-encapsulated MS. Our results show that the depletion of DCs or MΦs alone only led to minor differences in the OVA-specific immune responses. However, simultaneous depletion of DCs and MΦs caused a strong reduction of primed effector cells, indicating a redundancy of both cell populations for the priming of PLGA MS-encapsulated Ag. Finally, we analyzed PLGA MS trafficking to draining lymph nodes after s.c. injection. It was evident that fluorescent particles accumulated within draining lymph nodes over time. Further analysis of PLGA MS-positive lymphatic cells revealed that mainly CD8(-) DCs and MΦs contained MS. Moreover, immune responses in BATF3 knockout mice lacking CD8(+) DCs were normal. The results presented in this work strongly suggest that in vivo cross-priming of PLGA MS-encapsulated Ag is performed by CD8(-) DCs and MΦs.
    MeSH term(s) Animals ; Antigen Presentation/immunology ; CD8 Antigens/biosynthesis ; CD8 Antigens/immunology ; Cell Separation ; Cross-Priming/immunology ; Dendritic Cells/immunology ; Dendritic Cells/metabolism ; Flow Cytometry ; Lactic Acid/immunology ; Macrophages/immunology ; Macrophages/metabolism ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Mice, Transgenic ; Microspheres ; Polyglycolic Acid
    Chemical Substances CD8 Antigens ; polylactic acid-polyglycolic acid copolymer ; Polyglycolic Acid (26009-03-0) ; Lactic Acid (33X04XA5AT)
    Language English
    Publishing date 2011-09-01
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 3056-9
    ISSN 1550-6606 ; 0022-1767 ; 1048-3233 ; 1047-7381
    ISSN (online) 1550-6606
    ISSN 0022-1767 ; 1048-3233 ; 1047-7381
    DOI 10.4049/jimmunol.1002084
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  9. Article: Box C/D small nucleolar RNA trafficking involves small nucleolar RNP proteins, nucleolar factors and a novel nuclear domain.

    Verheggen, C / Mouaikel, J / Thiry, M / Blanchard, J M / Tollervey, D / Bordonné, R / Lafontaine, D L / Bertrand, E

    The EMBO journal

    2001  Volume 20, Issue 19, Page(s) 5480–5490

    Abstract: Nucleolar localization of box C/D small nucleolar (sno) RNAs requires the box C/D motif and ... in vertebrates, involves transit through Cajal bodies (CB). We report that in yeast, overexpression of a box C/D ... C/D snoRNA accumulation in the NB was decreased by mutation of Srp40 and increased by mutation ...

    Abstract Nucleolar localization of box C/D small nucleolar (sno) RNAs requires the box C/D motif and, in vertebrates, involves transit through Cajal bodies (CB). We report that in yeast, overexpression of a box C/D reporter leads to a block in the localization pathway with snoRNA accumulation in a specific sub-nucleolar structure, the nucleolar body (NB). The human survival of motor neuron protein (SMN), a marker of gems/CB, specifically localizes to the NB when expressed in yeast, supporting similarities between these structures. Box C/D snoRNA accumulation in the NB was decreased by mutation of Srp40 and increased by mutation of Nsr1p, two related nucleolar proteins that are homologous to human Nopp140 and nucleolin, respectively. Box C/D snoRNAs also failed to accumulate in the NB, and became delocalized to the nucleoplasm, upon depletion of any of the core snoRNP proteins, Nop1p/fibrillarin, Snu13p, Nop56p and Nop5p/Nop58p. We conclude that snoRNP assembly occurs either in the nucleoplasm, or during transit of snoRNAs through the NB, followed by routing of the complete snoRNP to functional sites of ribosome synthesis.
    MeSH term(s) Active Transport, Cell Nucleus ; Cell Compartmentation ; Cell Nucleolus/metabolism ; Coiled Bodies/metabolism ; Fungal Proteins/metabolism ; Models, Biological ; Nuclear Proteins/metabolism ; Phosphoproteins/metabolism ; RNA, Small Nucleolar/metabolism ; RNA-Binding Proteins ; Ribonucleoproteins, Small Nucleolar/metabolism ; Saccharomyces cerevisiae ; Saccharomyces cerevisiae Proteins ; Serine-Arginine Splicing Factors
    Chemical Substances Fungal Proteins ; NOP1 protein, S cerevisiae ; NOP58 protein, S cerevisiae ; NSR1 protein, S cerevisiae ; Nuclear Proteins ; Phosphoproteins ; RNA, Small Nucleolar ; RNA-Binding Proteins ; Ribonucleoproteins, Small Nucleolar ; Saccharomyces cerevisiae Proteins ; Serine-Arginine Splicing Factors (170974-22-8)
    Language English
    Publishing date 2001-10-01
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 586044-1
    ISSN 1460-2075 ; 0261-4189
    ISSN (online) 1460-2075
    ISSN 0261-4189
    DOI 10.1093/emboj/20.19.5480
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  10. Article ; Online: Long-term changes in

    Yoschenko, Vasyl / Thiry, Yves / Holiaka, Dmytrii / Levchuk, Sviatoslav / Kashparov, Valery / Nanba, Kenji

    Journal of environmental radioactivity

    2024  Volume 273, Page(s) 107366

    Abstract: The trenches of the waste burial site in the Chornobyl Red Forest represent a big reservoir of radionuclides for the artificial plantation of Scots pine established in that area, but the long term dynamics of tree biomass contamination, especially ... ...

    Abstract The trenches of the waste burial site in the Chornobyl Red Forest represent a big reservoir of radionuclides for the artificial plantation of Scots pine established in that area, but the long term dynamics of tree biomass contamination, especially with
    MeSH term(s) Biomass ; Chernobyl Nuclear Accident ; Radiation Monitoring ; Pinus sylvestris ; Forests ; Trees
    Language English
    Publishing date 2024-01-12
    Publishing country England
    Document type Journal Article
    ZDB-ID 1483112-0
    ISSN 1879-1700 ; 0265-931X
    ISSN (online) 1879-1700
    ISSN 0265-931X
    DOI 10.1016/j.jenvrad.2023.107366
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

To top