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  1. Article: NDM-1 Introduction in Portugal through a ST11 KL105

    Novais, Ângela / Ferraz, Rita Veiga / Viana, Mariana / da Costa, Paula Martins / Peixe, Luísa

    Antibiotics (Basel, Switzerland)

    2022  Volume 11, Issue 1

    Abstract: The changing epidemiology of carbapenem- ... ...

    Abstract The changing epidemiology of carbapenem-resistant
    Language English
    Publishing date 2022-01-12
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2681345-2
    ISSN 2079-6382
    ISSN 2079-6382
    DOI 10.3390/antibiotics11010092
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Hepatology in the COVID Era: Another C Virus, again Challenging the Liver.

    Peixe, Paula / Calinas, Filipe / Tato Marinho, Rui

    GE Portuguese journal of gastroenterology

    2020  Volume 27, Issue 4, Page(s) 230–236

    Keywords covid19
    Language English
    Publishing date 2020-04-30
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2835774-7
    ISSN 2387-1954 ; 2341-4545
    ISSN (online) 2387-1954
    ISSN 2341-4545
    DOI 10.1159/000508116
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  3. Article ; Online: Alert for molecular data interpretation when using Enterococcus faecium reference strains reclassified as Enterococcus lactis.

    Novais, Carla / Almeida-Santos, Ana C / Paula Pereira, Ana / Rebelo, Andreia / Freitas, Ana R / Peixe, Luísa

    Gene

    2022  Volume 851, Page(s) 146951

    MeSH term(s) Enterococcus faecium/genetics ; Enterococcus ; Enterococcus faecalis ; Anti-Bacterial Agents
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2022-10-17
    Publishing country Netherlands
    Document type Letter
    ZDB-ID 391792-7
    ISSN 1879-0038 ; 0378-1119
    ISSN (online) 1879-0038
    ISSN 0378-1119
    DOI 10.1016/j.gene.2022.146951
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1357: Show issues Location:
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  4. Article ; Online: Hepatology in the COVID Era

    Paula Peixe / Filipe Calinas / Rui Tato Marinho

    GE: Portuguese Journal of Gastroenterology, Vol 27, Iss 4, Pp 230-

    Another C Virus, again Challenging the Liver

    2020  Volume 236

    Keywords cirrhosis ; coronavirus ; covid-19 ; liver ; Diseases of the digestive system. Gastroenterology ; RC799-869 ; covid19
    Language English
    Publishing date 2020-04-01T00:00:00Z
    Publisher Karger Publishers
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article: Capsule endoscopy: beyond the small bowel.

    Relvas, Luís / Velasco, Francisco / Barros, Sónia / Carvalho, Isabel / Portugal, Margarida / Caldeira, Paulo / Peixe, Bruno

    Revista espanola de enfermedades digestivas

    2024  

    Abstract: Capsule endoscopy (CE) is considered the first-line for the investigation of OGIB after conventional non-diagnostic endoscopic examinations. A detection rate of lesions outside the small bowel segment has been reported to range from 3.5% to >30%. Our ... ...

    Abstract Capsule endoscopy (CE) is considered the first-line for the investigation of OGIB after conventional non-diagnostic endoscopic examinations. A detection rate of lesions outside the small bowel segment has been reported to range from 3.5% to >30%. Our primary objective was to analyze the role of CE in identifying lesions outside the small bowel segment that were not identified on conventional endoscopy in patients suspected of OGIB. In our study, CE appears to be effective and safe in diagnosing OGIB, also proving to be a tool in identifying lesions outside the small intestine segment.
    Language English
    Publishing date 2024-04-18
    Publishing country Spain
    Document type Journal Article
    ZDB-ID 1070381-0
    ISSN 1130-0108 ; 0212-7512
    ISSN 1130-0108 ; 0212-7512
    DOI 10.17235/reed.2024.10449/2024
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    In stock of ZB MED Cologne/Königswinter

    Zs.B 199: Show issues Location:
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  7. Article ; Online: Unraveling

    Pereira, Ana P / Antunes, Patrícia / Bierge, Paula / Willems, Rob J L / Corander, Jukka / Coque, Teresa M / Pich, Oscar Q / Peixe, Luisa / Freitas, Ana R / Novais, Carla

    Microbiology spectrum

    2023  , Page(s) e0232423

    Abstract: Quaternary ammonium compounds (QACs) have been extensively used in the community, healthcare facilities, and food chain, in concentrations between 20 and 30,000 mg/L. ...

    Abstract Quaternary ammonium compounds (QACs) have been extensively used in the community, healthcare facilities, and food chain, in concentrations between 20 and 30,000 mg/L.
    Language English
    Publishing date 2023-09-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2807133-5
    ISSN 2165-0497 ; 2165-0497
    ISSN (online) 2165-0497
    ISSN 2165-0497
    DOI 10.1128/spectrum.02324-23
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  8. Article: Hepatocellular Carcinoma in Chronic Hepatitis B Patients on Third Generation Nucleos(t)ides Analogs: Risk Factors and Performance of a Risk Score.

    Magalhães-Costa, Pedro / Lebre, Luís / Peixe, Paula / Santos, Sofia / Chagas, Cristina

    GE Portuguese journal of gastroenterology

    2016  Volume 23, Issue 5, Page(s) 233–242

    Abstract: Objective: To investigate hepatocellular carcinoma (HCC) incidence, risk factors and the performance of baseline REACH-B risk score in a Portuguese chronic hepatitis B (CHB) population on antiviral therapy.: Methods: Retrospective study of CHB ... ...

    Abstract Objective: To investigate hepatocellular carcinoma (HCC) incidence, risk factors and the performance of baseline REACH-B risk score in a Portuguese chronic hepatitis B (CHB) population on antiviral therapy.
    Methods: Retrospective study of CHB patients who were treated with tenofovir or entecavir for at least 12 months. Multivariate analysis was performed to identify factors associated with HCC. The Kaplan-Meier method was used to estimate the cumulative incidence of HCC at 1, 3 and 5 years on therapy. The performance of the REACH-B score at baseline was assessed.
    Results: One hundred and twenty patients initiated nucleos(t)ide analogs (NUC) therapy (age, 47 ± 14 years-old; 83 male; 11% had cirrhosis; 71% tenofovir; 73% HBeAg-negative; 61% treatment-naïve). After a median time under NUC of 39 months, 9 patients (7.5%) developed HCC. The calculated cumulative incidence rates of HCC at 1, 3 and 5 years on therapy were 5.1%, 7.3% and 8.8%, respectively. Independent predictors for HCC occurrence: age and cirrhosis at baseline. Diagnostic accuracy of baseline REACH-B score in predicting HCC development: AUC 0.738, 95%CI: 0.521-0.955. The cutoff value of 8 points had a sensitivity, specificity, positive predictive value and negative predictive value of 75%, 52%, 6% and 98%, respectively in predicting HCC occurrence during therapy.
    Conclusions: Older age and cirrhosis at baseline were independent predictors for HCC development. Discriminatory performance of baseline REACH-B score was limited.
    Language English
    Publishing date 2016-04-05
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2835774-7
    ISSN 2387-1954 ; 2341-4545
    ISSN (online) 2387-1954
    ISSN 2341-4545
    DOI 10.1016/j.jpge.2016.02.001
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  9. Article ; Online: Imported poultry meat as a source of extended-spectrum cephalosporin-resistant CMY-2-producing Salmonella Heidelberg and Salmonella Minnesota in the European Union, 2014-2015.

    Campos, Joana / Mourão, Joana / Silveira, Leonor / Saraiva, Margarida / Correia, Cristina Belo / Maçãs, Ana Paula / Peixe, Luísa / Antunes, Patrícia

    International journal of antimicrobial agents

    2018  Volume 51, Issue 1, Page(s) 151–154

    Abstract: Extended-spectrum cephalosporin (ESC)-resistant Salmonella have been described at a low level in the EU, nevertheless the increasing importation of poultry meat could be an important source of epidemic strains carrying ESC resistance genes. This study ... ...

    Abstract Extended-spectrum cephalosporin (ESC)-resistant Salmonella have been described at a low level in the EU, nevertheless the increasing importation of poultry meat could be an important source of epidemic strains carrying ESC resistance genes. This study evaluated ESC resistance and its genetic platform among Salmonella isolates from poultry meat products imported into Portugal as well as clonal relatedness of the isolates. All Salmonella isolates recovered from samples of fresh meat destined for import into the EU in the scope of Portuguese official border control (2014-2015) were studied. Antibiotic susceptibility and β-lactamase production was determined by disk diffusion/microdilution. Molecular studies included detection of genes encoding acquired AmpC and extended-spectrum β-lactamases, plasmid-mediated quinolone resistance and other antibiotic resistance genes by PCR/sequencing, and clonality by MLST and XbaI-PFGE. Plasmid characterisation was assessed by conjugation assays, replicon typing (PCR-PBRT/pMLST) and hybridisation experiments (I-CeuI/S1-PFGE nuclease). Isolates belonged to Salmonella Heidelberg (n = 6; ST15/eBG26) and Salmonella Minnesota (n = 1; ST548/eBG77) and presented multidrug-resistant profiles, including to ESCs and/or fluoroquinolones. All but one carried bla
    MeSH term(s) Animals ; Bacterial Proteins/genetics ; Cephalosporins/pharmacology ; Drug Resistance, Multiple, Bacterial/genetics ; European Union ; Fluoroquinolones/pharmacology ; Food Microbiology ; Food Safety ; Humans ; Plasmids/genetics ; Poultry/microbiology ; Salmonella/drug effects ; Salmonella/genetics ; Salmonella/isolation & purification ; Salmonella Food Poisoning/microbiology ; Salmonella Food Poisoning/prevention & control ; beta-Lactamases/genetics
    Chemical Substances Bacterial Proteins ; Cephalosporins ; Fluoroquinolones ; beta-lactamase CMY-2 (EC 3.5.2.-) ; AmpC beta-lactamases (EC 3.5.2.6) ; beta-Lactamases (EC 3.5.2.6)
    Language English
    Publishing date 2018-01
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1093977-5
    ISSN 1872-7913 ; 0924-8579
    ISSN (online) 1872-7913
    ISSN 0924-8579
    DOI 10.1016/j.ijantimicag.2017.09.006
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3368: Show issues Location:
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    Zs.MO 500: Show issues

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  10. Article ; Online: The who-when-why triangle of CAM use among Portuguese IBD patients.

    Portela, Francisco / Dias, Camila C / Caldeira, Paulo / Cravo, Marilia / Deus, João / Gonçalves, Raquel / Lago, Paula / Morna, Henrique / Peixe, Paula / Ramos, Jaime / Sousa, Helena / Tavares, Lurdes / Vasconcelos, Helena / Magro, Fernando / Ministro, Paula

    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver

    2017  Volume 49, Issue 4, Page(s) 388–396

    Abstract: Background: The use of complementary and alternative medicines is increasing among chronic patients, particularly those afflicted with inflammatory bowel diseases.: Aim: This study aimed to address the prevalence of complementary and alternative ... ...

    Abstract Background: The use of complementary and alternative medicines is increasing among chronic patients, particularly those afflicted with inflammatory bowel diseases.
    Aim: This study aimed to address the prevalence of complementary and alternative medicines use among Portuguese inflammatory bowel diseases' patients.
    Methods: Patients were invited to fill an anonymous questionnaire concerning the use of complementary and alternative medicines.
    Results: Thirty-one per cent of the patients reported having used complementary and alternative medicines in the past, whereas 12% were using them by the time the questionnaire was administered. Fifty-nine per cent of the users did not share this information with their physician, whereas 14% and 8% discontinued their medication and periodical examination, respectively. Steroids prescription (OR=2.880) and a higher instruction level (OR=3.669) were predictors of complementary and alternative medicines use in this cohort.
    Conclusions: Roughly a third of Portuguese IBD patients had used CAM. Steroid treatment and an academic degree are associated with CAM use. Given the potential side effects and interactions, patient information about the benefits and limitations of conventional and complementary treatments should be reinforced.
    MeSH term(s) Adult ; Cohort Studies ; Complementary Therapies/utilization ; Female ; Humans ; Inflammatory Bowel Diseases/therapy ; Logistic Models ; Male ; Middle Aged ; Patient Compliance/statistics & numerical data ; Portugal ; Steroids/therapeutic use ; Surveys and Questionnaires ; Treatment Outcome
    Chemical Substances Steroids
    Language English
    Publishing date 2017-04
    Publishing country Netherlands
    Document type Journal Article ; Multicenter Study
    ZDB-ID 1459373-7
    ISSN 1878-3562 ; 1125-8055
    ISSN (online) 1878-3562
    ISSN 1125-8055
    DOI 10.1016/j.dld.2016.12.031
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1134: Show issues Location:
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