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  1. Article ; Online: Devices and furniture for small and sick newborn care: systematic development of a planning and costing tool.

    Tarus, Alice / Msemo, Georgina / Kamuyu, Rosemary / Shamba, Donat / Kirby, Rebecca P / Palamountain, Kara M / Gicheha, Edith / Kumar, Meghan Bruce / Powell-Jackson, Timothy / Bohne, Christine / Murless-Collins, Sarah / Liaghati-Mobarhan, Sara / Morgan, Alison / Oden, Z Maria / Richards-Kortum, Rebecca / Lawn, Joy E

    BMC pediatrics

    2023  Volume 23, Issue Suppl 2, Page(s) 566

    Abstract: Background: High-quality neonatal care requires sufficient functional medical devices, furniture, fixtures, and use by trained healthcare workers, however there is lack of publicly available tools for quantification and costing. This paper describes ... ...

    Abstract Background: High-quality neonatal care requires sufficient functional medical devices, furniture, fixtures, and use by trained healthcare workers, however there is lack of publicly available tools for quantification and costing. This paper describes development and use of a planning and costing tool regarding furniture, fixtures and devices to support scale-up of WHO level-2 neonatal care, for national and global newborn survival targets.
    Methods: We followed a systematic process. First, we reviewed planning and costing tools of relevance. Second, we co-designed a new tool to estimate furniture and device set-up costs for a default 40-bed level-2 neonatal unit, incorporating input from multi-disciplinary experts and newborn care guidelines. Furniture and device lists were based off WHO guidelines/norms, UNICEF and national manuals/guides. Due to lack of evidence-based quantification, ratios were based on operational manuals, multi-country facility assessment data, and expert opinion. Default unit costs were from government procurement agency costs in Kenya, Nigeria, and Tanzania. Third, we refined the tool by national use in Tanzania.
    Results: The tool adapts activity-based costing (ABC) to estimate quantities and costs to equip a level-2 neonatal unit based on three components: (1) furniture/fixtures (18 default but editable items); (2) neonatal medical devices (16 product categories with minimum specifications for use in low-resource settings); (3) user training at device installation. The tool was used in Tanzania to generate procurement lists and cost estimates for level-2 scale-up in 171 hospitals (146 District and 25 Regional Referral). Total incremental cost of all new furniture and equipment acquisition, installation, and user training were US$93,000 per District hospital (level-2 care) and US$346,000 per Regional Referral hospital. Estimated cost per capita for whole-country district coverage was US$0.23, representing 0.57% increase in government health expenditure per capita and additional 0.35% for all Regional Referral hospitals.
    Conclusion: Given 2.3 million neonatal deaths and potential impact of level-2 newborn care, rational and efficient planning of devices linked to systems change is foundational. In future iterations, we aim to include consumables, spare parts, and maintenance cost options. More rigorous implementation research data are crucial to formulating evidence-based ratios for devices numbers per baby. Use of this tool could help overcome gaps in devices numbers, advance efficiency and quality of neonatal care.
    MeSH term(s) Infant ; Infant, Newborn ; Female ; Humans ; Interior Design and Furnishings ; Perinatal Death ; Tanzania ; Kenya ; Nigeria
    Language English
    Publishing date 2023-11-15
    Publishing country England
    Document type Review ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2041342-7
    ISSN 1471-2431 ; 1471-2431
    ISSN (online) 1471-2431
    ISSN 1471-2431
    DOI 10.1186/s12887-023-04363-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Practice ownership.

    Reader, Jon / Davies, Andrew / Masters, Jo / Hayton, Alastair / Clarke, Tom / Powell-Jackson, Ed / Shardlow, Tom / Hayton, Rachel / Foden, Gareth / McPherson, Graeme / Moffett, Alasdair / Moffett, Esme / Gascoigne, Emily / Frecknall, Dave / Phillips, Dave / Barber, Ben / Hunt, Paula / O'Malley, Pete

    The Veterinary record

    2022  Volume 190, Issue 2, Page(s) 78

    MeSH term(s) Animals ; Ownership ; Surveys and Questionnaires
    Language English
    Publishing date 2022-01-21
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 390015-0
    ISSN 2042-7670 ; 0042-4900
    ISSN (online) 2042-7670
    ISSN 0042-4900
    DOI 10.1002/vetr.1413
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Effect and cost-effectiveness of educating mothers about childhood DPT vaccination on immunisation uptake, knowledge, and perceptions in Uttar Pradesh, India

    Timothy Powell-Jackson / Camilla Fabbri / Varun Dutt / Sarah Tougher / Kultar Singh

    PLoS Medicine, Vol 15, Iss 3, p e

    A randomised controlled trial.

    2018  Volume 1002519

    Abstract: ... information groups, giving a risk difference of 15 percentage points (95% CI: 7% to 22%, p < 0.001) and ... a relative risk of 1.52 (95% CI: 1.2 to 1.9, p < 0.001). The information intervention increased the rate ... of measles vaccination by 22 percentage points (risk difference: 22%, 95% CI: 14% to 30%, p < 0.001; relative ...

    Abstract BACKGROUND:To assess the effect of health information on immunisation uptake in rural India, we conducted an individually randomised controlled trial of health information messages targeting the mothers of unvaccinated or incompletely vaccinated children through home visits in rural Uttar Pradesh, India. METHODS AND FINDINGS:The study tested a brief intervention that provided mothers face-to-face with information on the benefits of the tetanus vaccine. Participants were 722 mothers of children aged 0-36 months who had not received 3 doses of diphtheria-pertussis-tetanus (DPT) vaccine (DPT3). Mothers were randomly assigned in a ratio of 1:1:1 to 1 of 3 study arms: mothers in the first treatment group received information framed as a gain (e.g., the child is less likely to get tetanus and more likely to be healthy if vaccinated), mothers in the second treatment group received information framed in terms of a loss (e.g., the child is more likely to get tetanus and suffer ill health if not vaccinated), and the third arm acted as a control group, with no information given to the mother. Surveys were conducted at baseline (September 2015) and after the intervention (April 2016). The primary outcome was the proportion of children who had received DPT3 measured after 7 months of follow-up. The analysis was by intention to treat. A total of 16 (2.2%) participants were lost to follow-up. The coverage of DPT3 was 28% in the control group and 43% in the pooled information groups, giving a risk difference of 15 percentage points (95% CI: 7% to 22%, p < 0.001) and a relative risk of 1.52 (95% CI: 1.2 to 1.9, p < 0.001). The information intervention increased the rate of measles vaccination by 22 percentage points (risk difference: 22%, 95% CI: 14% to 30%, p < 0.001; relative risk: 1.53, 95% CI: 1.29 to 1.80) and the rate of full immunisation by 14 percentage points (risk difference: 14%, 95% CI: 8% to 21%, p < 0.001; relative risk: 1.72, 95% CI: 1.29 to 2.29). It had a large positive effect on knowledge of the ...
    Keywords Medicine ; R
    Subject code 360
    Language English
    Publishing date 2018-03-01T00:00:00Z
    Publisher Public Library of Science (PLoS)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Delivering medical abortion at scale

    Timothy Powell-Jackson / Rajib Acharya / Veronique Filippi / Carine Ronsmans

    PLoS ONE, Vol 10, Iss 3, p e

    a study of the retail market for medical abortion in Madhya Pradesh, India.

    2015  Volume 0120637

    Abstract: Medical abortion (mifepristone and misoprostol) has the potential to contribute to reduced maternal mortality but little is known about the provision or quality of advice for medical abortion through the private retail sector. We examined the ... ...

    Abstract Medical abortion (mifepristone and misoprostol) has the potential to contribute to reduced maternal mortality but little is known about the provision or quality of advice for medical abortion through the private retail sector. We examined the availability of medical abortion and the practices of pharmacists in India, where abortion has been legal since 1972.We interviewed 591 pharmacists in 60 local markets in city, town and rural areas of Madhya Pradesh. One month later, we returned to 359 pharmacists with undercover patients who presented themselves unannounced as genuine customers seeking a medical abortion.Medical abortion was offered to undercover patients by 256 (71.3%) pharmacists and 24 different brands were identified. Two thirds (68.5%) of pharmacists stated that abortion was illegal in India. Only 106 (38.5%) pharmacists asked clients the timing of the last menstrual period and 38 (13.8%) requested to see a doctor's prescription - a legal requirement in India. Only 59 (21.5%) pharmacists correctly advised patients on the gestational limit for medical abortion, 97 (35.3%) provided correct information on how many and when to take the tablets in a combination pack, and 78 (28.4%) gave accurate advice on where to seek care in case of complications. Advice on post-abortion family planning was almost nonexistent.The retail market for medical abortion is extensive, but the quality of advice given to patients is poor. Although the contribution of medical abortion to women's health in India is poorly understood, there is an urgent need to improve the practices of pharmacists selling medical abortion.
    Keywords Medicine ; R ; Science ; Q
    Subject code 170
    Language English
    Publishing date 2015-01-01T00:00:00Z
    Publisher Public Library of Science (PLoS)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Effect of Paying for Performance on Utilisation, Quality, and User Costs of Health Services in Tanzania

    Peter Binyaruka / Edith Patouillard / Timothy Powell-Jackson / Giulia Greco / Ottar Maestad / Josephine Borghi

    PLoS ONE, Vol 10, Iss 8, p e

    A Controlled Before and After Study.

    2015  Volume 0135013

    Abstract: Despite widespread implementation across Africa, there is limited evidence of the effect of payment for performance (P4P) schemes in low income countries on the coverage of quality services and affordability, consistent with universal health coverage ... ...

    Abstract Despite widespread implementation across Africa, there is limited evidence of the effect of payment for performance (P4P) schemes in low income countries on the coverage of quality services and affordability, consistent with universal health coverage objectives. We examined the effect of a government P4P scheme on utilisation, quality, and user costs of health services in Tanzania.We evaluated the effects of a P4P scheme on utilisation of all maternal and child immunization services targeted by the scheme, and non-targeted general outpatient service use. We also evaluated effects on patient satisfaction with care and clinical content of antenatal care, and user costs. The evaluation was done in 150 facilities across all 7 intervention districts and 4 comparison districts with two rounds of data collection over 13-months in January 2012 and February 2013. We sampled 3000 households of women who had delivered in the 12 months prior to interview; 1500 patients attending health facilities for targeted and non-targeted services at each round of data collection. Difference-in-difference regression analysis was employed.We estimated a significant positive effect on two out of eight targeted indicators. There was an 8.2% (95% CI: 3.6% to 12.8%) increase in coverage of institutional deliveries among women in the intervention area, and a 10.3% (95% CI: 4.4% to 16.1%) increase in the provision of anti-malarials during pregnancy. Use of non-targeted services reduced at dispensaries by 57.5 visits per month among children under five (95% CI: -110.2 to -4.9) and by 90.8 visits per month for those aged over five (95% CI: -156.5 to -25.2). There was no evidence of an effect of P4P on patient experience of care for targeted services. There was a 0.05 (95% CI: 0.01 to 0.10) increase in the patient satisfaction score for non-targeted services. P4P was associated with a 5.0% reduction in those paying out of pocket for deliveries (95% CI: -9.3% to -0.7%) but there was no evidence of an effect on the average amount paid.This study ...
    Keywords Medicine ; R ; Science ; Q
    Subject code 360
    Language English
    Publishing date 2015-01-01T00:00:00Z
    Publisher Public Library of Science (PLoS)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Physician-Led Thoracic Trauma Management in a Specialist Emergency Care Centre

    Jonathan Bates-Powell / David Basterfield / Karl Jackson / Avinash Aujayeb

    Journal of Clinical Medicine, Vol 10, Iss 5806, p

    2021  Volume 5806

    Abstract: Introduction: Falls cause 75% of trauma in patients above 65 years of age, and thoracic trauma is the second commonest injury; rib fractures are the most common thoracic injury. These patients have up to 12% mortality, with 31% developing pneumonias. ... ...

    Abstract Introduction: Falls cause 75% of trauma in patients above 65 years of age, and thoracic trauma is the second commonest injury; rib fractures are the most common thoracic injury. These patients have up to 12% mortality, with 31% developing pneumonias. There is wide variation in care. Northumbria Healthcare has a team of respiratory consultants, physiotherapists, specialist nurses and anesthetists for thoracic-trauma management on a respiratory support unit. Methods: With Caldicott approval, basic demographics and clinical outcomes of patients admitted with thoracic trauma between 20 August–21 April were analyzed. A descriptive statistical methodology was applied. Results: A total of 119 patients were identified with a mean age of 71.1 years (range 23–97). Of the 119 patients, 53 were male, 66 females. The main mechanism of injury was falls from standing (65) and falls down stairs/bed or in the bath (18). Length of stay was 7.3 days (range 1–54). In total, 85 patients had more than one co-morbidity, 26 had a full trauma assessment and 75 had pan CTs. The mean number of rib fractures was 3.6 and 31 (26%) patients had a pneumothorax and/or haemothorax. A total of 18 chest drains were inserted (all small bore) and one needle aspiration was performed. No cardiothoracic input was required. Isolated chest trauma was present only in 45 patients. All patients had a pain team review, 22 erector spinae catheters were inserted with 2 paravertebral blocks. Overall, 82 patients did not require oxygen, 1 required CPAP and 1 HFNC. 7 needed intensive care transfer. Furthermore, 20 (17%) developed pneumonias and 16 (14%) deaths occurred within 30 days—all were in those with falls from standing. There was no correlation between number of fractured ribs, length of stay and mortality. Conclusions: High level care for thoracic trauma can be performed by a physician led team. Overall, 42% pneumothoraces/haemothoraces were observed. Further large scale randomised trials are warranted for definitive outcomes.
    Keywords trauma ; rib fractures ; thoracic trauma ; Medicine ; R
    Subject code 610
    Language English
    Publishing date 2021-12-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Childhood Bereavement, Adverse and Positive Childhood Experiences, and Flourishing among Chinese Young Adults

    Krista P. Woodward / Zhiyuan Yu / Wenyi Chen / Tingting Chen / Dylan B. Jackson / Terrinieka W. Powell / Lin Wang

    International Journal of Environmental Research and Public Health, Vol 20, Iss 4631, p

    2023  Volume 4631

    Abstract: ... 0.35, t = −4.19, p < 0.001) and Secure Flourishing Index (β = −0.40, t = −4.96, p < 0.001 ...

    Abstract Childhood bereavement (CB) resulting from a parent or primary caregiver death is associated with a range of adverse outcomes. Little is known about the association between CB and adult flourishing in the context of adverse childhood experiences (ACEs) and positive childhood experiences (PCEs). In a cross-sectional observational study, we examined how ACEs, PCEs, and adult flourishing differs by self-reported CB history among 9468 Chinese young adults (18–35 years), of which 4.3% experienced CB ( n = 409). Data collection included convenience sampling among university students in Mainland China. Respondents voluntarily completed an online survey between August and November 2020. Descriptive statistics, chi-square tests, and logistic regressions examined frequencies and differences in ACEs, PCEs, and flourishing by the history of CB controlling for a few demographic covariates. Bereaved individuals reported significantly higher ACEs and lower PCEs. The odds of experiencing emotional, physical, and sexual abuse as well as household substance abuse, parental mental illness, and parental incarceration ranged from 2.0–5.2 times higher for bereaved individuals. Bereaved participants also reported significant negative relationships with Flourishing Index (β = −0.35, t = −4.19, p < 0.001) and Secure Flourishing Index (β = −0.40, t = −4.96, p < 0.001). Consistent with previous research, our findings demonstrate the lasting effects of CB on well-being. We discuss study implications for ACEs and PCEs screening and surveillance as well as grief counseling to promote flourishing among bereaved youth in China and beyond.
    Keywords childhood bereavement ; childhood grief ; adverse childhood experiences ; positive childhood experiences ; adult flourishing ; Medicine ; R
    Subject code 360
    Language English
    Publishing date 2023-03-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article: Use of flupirtine maleate as an analgesic in patients with liver disease.

    Powell-Jackson, P / Williams, R

    The British journal of clinical practice

    1985  Volume 39, Issue 2, Page(s) 63–66

    MeSH term(s) Adult ; Aged ; Aminopyridines/adverse effects ; Aminopyridines/metabolism ; Aminopyridines/therapeutic use ; Analgesics/therapeutic use ; Female ; Humans ; Liver Diseases/drug therapy ; Liver Diseases/metabolism ; Male ; Middle Aged ; Palliative Care
    Chemical Substances Aminopyridines ; Analgesics ; flupirtine (MOH3ET196H)
    Language English
    Publishing date 1985-02
    Publishing country England
    Document type Journal Article
    ZDB-ID 127432-6
    ISSN 0007-0947
    ISSN 0007-0947
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Nutrition and Physical Activity During British Army Officer Cadet Training: Part 1-Energy Balance and Energy Availability.

    Edwards, Victoria C / Myers, Stephen D / Wardle, Sophie L / Siddall, Andrew G / Powell, Steven D / Needham-Beck, Sarah / Kefyalew, Sarah S / Singh, Priya A / Orford, Elise R / Venables, Michelle C / Jackson, Sarah / Greeves, Julie P / Blacker, Sam D

    International journal of sport nutrition and exercise metabolism

    2022  Volume 32, Issue 3, Page(s) 195–203

    Abstract: ... with CAMP (-692 ± 506 kcal/day; p < .001) and MIX (-1,280 ± 309 kcal/day; p < .001). EA was greatest in CAMP ... 23 ± 10 kcal·kg free-fat mass [FFM]-1·day-1) compared with FEX (1 ± 16 kcal·kg FFM-1·day-1; p = .002 ... and MIX (10 ± 7 kcal·kg FFM-1·day-1; p = .003), with no apparent difference between FEX and MIX (p ...

    Abstract Military training is characterized by high daily energy expenditures which are difficult to match with energy intake, potentially resulting in negative energy balance (EB) and low energy availability (EA). The aim of this study was to quantify EB and EA during British Army Officer Cadet training. Thirteen (seven women) Officer Cadets (mean ± SD: age 24 ± 3 years) volunteered to participate. EB and EA were estimated from energy intake (weighing of food and food diaries) and energy expenditure (doubly labeled water) measured in three periods of training: 9 days on-camp (CAMP), a 5-day field exercise (FEX), and a 9-day mixture of both CAMP and field-based training (MIX). Variables were compared by condition and gender with a repeated-measures analysis of variance. Negative EB was greatest during FEX (-2,197 ± 455 kcal/day) compared with CAMP (-692 ± 506 kcal/day; p < .001) and MIX (-1,280 ± 309 kcal/day; p < .001). EA was greatest in CAMP (23 ± 10 kcal·kg free-fat mass [FFM]-1·day-1) compared with FEX (1 ± 16 kcal·kg FFM-1·day-1; p = .002) and MIX (10 ± 7 kcal·kg FFM-1·day-1; p = .003), with no apparent difference between FEX and MIX (p = .071). Irrespective of condition, there were no apparent differences between gender in EB (p = .375) or EA (p = .385). These data can be used to inform evidenced-based strategies to manage EA and EB during military training, and enhance the health and performance of military personnel.
    MeSH term(s) Adult ; Energy Intake ; Energy Metabolism ; Exercise ; Female ; Humans ; Military Personnel ; Nutritional Status ; Young Adult
    Language English
    Publishing date 2022-04-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1101115-4
    ISSN 1543-2742 ; 1050-1606 ; 1526-484X
    ISSN (online) 1543-2742
    ISSN 1050-1606 ; 1526-484X
    DOI 10.1123/ijsnem.2021-0190
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Interaction between azapropazone and warfarin.

    Powell-Jackson, P R

    British medical journal

    1977  Volume 1, Issue 6070, Page(s) 1193–1194

    MeSH term(s) Apazone/pharmacology ; Drug Interactions ; Female ; Humans ; Middle Aged ; Triazines/pharmacology ; Warfarin/pharmacology
    Chemical Substances Triazines ; Warfarin (5Q7ZVV76EI) ; Apazone (K2VOT966ZI)
    Language English
    Publishing date 1977-05-07
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 80088-0
    ISSN 0007-1447 ; 0267-0623 ; 0959-8138 ; 0959-8146
    ISSN 0007-1447 ; 0267-0623 ; 0959-8138 ; 0959-8146
    DOI 10.1136/bmj.1.6070.1193-a
    Database MEDical Literature Analysis and Retrieval System OnLINE

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