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  1. Article: (with research data) Herbivores alter plant-wind interactions by acting as a point mass on leaves and by removing leaf tissue.

    Kothari, Adit R / Burnett, Nicholas P

    Ecology and evolution

    2017  Volume 7, Issue 17, Page(s) 6884–6893

    Abstract: In nature, plants regularly interact with herbivores and with wind. Herbivores can wound and alter the structure of plants, whereas wind can exert aerodynamic forces that cause the plants to flutter or sway. While herbivory has many negative consequences ...

    Abstract In nature, plants regularly interact with herbivores and with wind. Herbivores can wound and alter the structure of plants, whereas wind can exert aerodynamic forces that cause the plants to flutter or sway. While herbivory has many negative consequences for plants, fluttering in wind can be beneficial for plants by facilitating gas exchange and loss of excess heat. Little is known about how herbivores affect plant motion in wind. We tested how the mass of an herbivore resting on a broad leaf of the tulip tree
    Language English
    Publishing date 2017-07-27
    Publishing country England
    Document type Journal Article
    ZDB-ID 2635675-2
    ISSN 2045-7758
    ISSN 2045-7758
    DOI 10.1002/ece3.3249
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Detection and distribution of genotypes of Hepatitis C in a tertiary care hospital

    Upasana Bhumbla / Laveena Shekhawat / Aditi Kothari / Jatin Rao

    Journal of Family Medicine and Primary Care, Vol 9, Iss 10, Pp 5249-

    2020  Volume 5251

    Abstract: Hepatitis C virus (HCV) has emerged as a leading cause of chronic hepatitis and hepatocellular carcinoma. Thus, this study was undertaken for detection and to observe genotypic distribution of the virus in this geographical region. Aims and Objectives: ... ...

    Abstract Hepatitis C virus (HCV) has emerged as a leading cause of chronic hepatitis and hepatocellular carcinoma. Thus, this study was undertaken for detection and to observe genotypic distribution of the virus in this geographical region. Aims and Objectives: The aim of the study was to quantitatively detect HCV RNA in Hepatitis C patients and to determine the distribution pattern of its genotypes by real time polymerase chain reaction. Materials and Methods: This is a retrospective study conducted in a tertiary care hospital. In seropositive Hepatitis C patients, quantification of HCV-RNA was done by real time PCR and in HCV-RNA positive samples, genotyping for HCV was conducted. Result: A total of 300 patients were recruited in the study, of which 165 were anti HCV positive and among them, 127 were HCV-RNA positive. These positive samples were further subjected to genotype determination using real time PCR. 98 samples were positive for genotype, where genotype 3 was seen in 90 patients, genotype 1, in 3 patients and genotype 4, in 5 patients. Conclusion: Knowledge of genotype is crucial for management of HCV infection and prediction of prognosis. Patients infected with HCV genotype 1 and 4 will have to receive IFN and ribavirin for a period of 48 weeks and show a poor sustained viral response. On the contrary, patients infected with HCV genotype 2 and 3 are reported to have better response to therapy.
    Keywords anti hcv ; hcv genotype ; hcv-rna ; hepatitis c virus ; Medicine ; R
    Subject code 360
    Language English
    Publishing date 2020-01-01T00:00:00Z
    Publisher Wolters Kluwer Medknow Publications
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article: Comparative Evaluation of the Effectiveness of Different Pain-alleviating Methods before Local Anesthetic Administration in Children of 6 to 12 Years of Age: A Clinical Study.

    Patil, Sudha B / Popali, Divya D / Bondarde, Prashant A / Khandare, Nikhil S / Kothari, Akshay R / Chawla, Pooja S / Gawale, Sayali / Shinde, Gaurav A / Agrawal, Rachana S / Patkar, Aditi S / Mirgal, Saurabh R

    International journal of clinical pediatric dentistry

    2021  Volume 14, Issue 4, Page(s) 447–453

    Abstract: Background and aim of the study: Pediatric patients are apprehensive regarding having dental treatment mainly because of painful local anesthetic (LA) injections. Various techniques like transcutaneous electrical nerve stimulation (TENS), topical ... ...

    Abstract Background and aim of the study: Pediatric patients are apprehensive regarding having dental treatment mainly because of painful local anesthetic (LA) injections. Various techniques like transcutaneous electrical nerve stimulation (TENS), topical anesthetic agents, and vibrator device are introduced to reduce discomfort before LA administration. Therefore, the present study aimed to compare and evaluate the effectiveness of TENS, 2% lignocaine gel, eutectic mixture of lignocaine and prilocaine (EMLA), and vibrating device before LA injections in alleviating pain in pediatric patients.
    Materials and methods: Sixty healthy children aged 6 to 12 years who required LA injections for dental procedures were selected and divided into four groups with 15 patients in each group. Wong-Baker's facial pain rating scale (WBFPRS) and face, legs, activity, cry, and consolability scale (FLACC) are used for pain perception which are tabulated, and statistically analyzed.
    Results: The test results demonstrated that the TENS group has shown the least mean WBFPRS and FLACC score, followed by vibrator devices, EMLA gel, and lignocaine gel.
    Conclusion: The newly introduced TENS apparatus showed encouraging results, hence can be used as a safe and reliable technique to be used in pediatric dentistry.
    How to cite this article: Patil SB, Popali DD, Bondarde PA,
    Language English
    Publishing date 2021-09-28
    Publishing country India
    Document type Journal Article
    ISSN 0974-7052
    ISSN 0974-7052
    DOI 10.5005/jp-journals-10005-1998
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Comprehensive Viral Genotyping Reveals Prognostic Viral Phylogenetic Groups in HPV16-Associated Squamous Cell Carcinoma of the Oropharynx.

    Schrank, Travis P / Landess, Lee / Stepp, Wesley H / Rehmani, Hina / Weir, William H / Lenze, Nicholas / Lal, Asim / Wu, Di / Kothari, Aditi / Hackman, Trevor G / Sheth, Siddharth / Patel, Shetal / Jefferys, Stuart R / Issaeva, Natalia / Yarbrough, Wendell G

    Molecular cancer research : MCR

    2022  Volume 20, Issue 10, Page(s) 1489–1501

    Abstract: Human papillomavirus-positive (HPV+) squamous cell carcinoma of the oropharynx (OPSCC) is the most prevalent HPV-associated malignancy in the United States and is primarily caused by HPV subtype 16 (HPV16). Favorable treatment outcomes have led to ... ...

    Abstract Human papillomavirus-positive (HPV+) squamous cell carcinoma of the oropharynx (OPSCC) is the most prevalent HPV-associated malignancy in the United States and is primarily caused by HPV subtype 16 (HPV16). Favorable treatment outcomes have led to increasing interest in treatment deescalation to reduce treatment-related morbidity. Prognostic biomarkers are needed to identify appropriately low-risk patients for reduced treatment intensity. Targeted DNA sequencing including all HPV16 open reading frames was performed on tumors from 104 patients with HPV16+ OPSCC treated at a single center. Genotypes closely related to the HPV16-A1 reference were associated with increased numbers of somatic copy-number variants in the human genome and poor recurrence-free survival (RFS). Genotypes divergent from HPV16-A1 were associated with favorable RFS. These findings were independent of tobacco smoke exposure. Total RNA sequencing was performed on a second independent cohort of 89 HPV16+ OPSCC cases. HPV16 genotypes divergent from HPV16-A1 were again validated in this independent cohort, to be prognostic of improved RFS in patients with moderate (less than 30 pack-years) or low (no more than 10 pack-years) of tobacco smoke exposure. In summary, we show in two independent cohorts that viral sequence divergence from the HPV16-A1 reference is correlated with improved RFS in patients with moderate or low tobacco smoke exposure.
    Implications: HPV16 genotype is a potential biomarker that could be easily adopted to guide therapeutic decision-making related to deescalation therapy.
    MeSH term(s) Carcinoma, Squamous Cell/pathology ; Genotype ; Human papillomavirus 16/genetics ; Humans ; Oropharyngeal Neoplasms/genetics ; Papillomavirus Infections/pathology ; Phylogeny ; Prognosis ; Tobacco Smoke Pollution
    Chemical Substances Tobacco Smoke Pollution
    Language English
    Publishing date 2022-06-22
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 2098788-2
    ISSN 1557-3125 ; 1541-7786
    ISSN (online) 1557-3125
    ISSN 1541-7786
    DOI 10.1158/1541-7786.MCR-21-0443
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  5. Article: Total laparoscopic repair of Spigelian hernia with undescended testis.

    Deshmukh, Shahaji Satish / Kothari, Paras R / Gupta, Abhaya R / Dikshit, Vishesh Balbhadra / Patil, Prashant / Kekre, Geeta Anil / Deshpande, Aditi / Kulkarni, Apoorva Achyut / Hukeri, Aboli

    Journal of minimal access surgery

    2019  Volume 15, Issue 3, Page(s) 265–267

    Abstract: Spigelian hernia is very rare in the paediatric age group. We present the case of an 11-month-old male child who presented with left Spigelian hernia with the left undescended testis in its sac. Hernia repair with orchidopexy was done using total ... ...

    Abstract Spigelian hernia is very rare in the paediatric age group. We present the case of an 11-month-old male child who presented with left Spigelian hernia with the left undescended testis in its sac. Hernia repair with orchidopexy was done using total laparoscopic approach. It is the first reported case of total laparoscopic repair of Spigelian hernia with undescended testis in the paediatric age group.
    Language English
    Publishing date 2019-01-04
    Publishing country India
    Document type Journal Article
    ZDB-ID 2186884-0
    ISSN 1998-3921 ; 0972-9941
    ISSN (online) 1998-3921
    ISSN 0972-9941
    DOI 10.4103/jmas.JMAS_196_18
    Database MEDical Literature Analysis and Retrieval System OnLINE

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