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Article ; Online: A case report of T cell prolymphocytic leukemia and Kaposi sarcoma and a review of T cell prolymphocytic leukemia.

Paul, R N / Alizadeh, L / Ajayi, O I / Karpurapu, H / Ganesan, C / Taddesse-Heath, L / Aggarwal, A

2012 Volume 127, Issue 4, Page(s) 235–243

Abstract: T cell prolymphocytic leukemia (T-PLL) is a rare mature T cell lymphoproliferative disease. It has ... median survival. Here we present a rare case of concurrent T-PLL and Kaposi sarcoma who achieved ... A review of T-PLL was done. In this review, clinical features, laboratory features and current therapeutic ...

Abstract	T cell prolymphocytic leukemia (T-PLL) is a rare mature T cell lymphoproliferative disease. It has been associated with an aggressive course, a poor response to conventional chemotherapy and a short median survival. Here we present a rare case of concurrent T-PLL and Kaposi sarcoma who achieved a complete hematologic and cytogenetic remission after a very short course of treatment with alemtuzumab. A review of T-PLL was done. In this review, clinical features, laboratory features and current therapeutic strategies of T-PLL are presented.
MeSH term(s)	Aged ; Aged, 80 and over ; Alemtuzumab ; Antibodies, Monoclonal, Humanized/therapeutic use ; Antigens, CD ; Antigens, Neoplasm ; Antineoplastic Agents/therapeutic use ; CD52 Antigen ; Glycoproteins/antagonists & inhibitors ; Humans ; Leukemia, Prolymphocytic, T-Cell/diagnosis ; Leukemia, Prolymphocytic, T-Cell/immunology ; Leukemia, Prolymphocytic, T-Cell/therapy ; Male ; Neoplasms, Multiple Primary/diagnosis ; Neoplasms, Multiple Primary/immunology ; Neoplasms, Multiple Primary/therapy ; Remission Induction ; Sarcoma, Kaposi/radiotherapy ; Sarcoma, Kaposi/therapy ; Time Factors
Chemical Substances	Antibodies, Monoclonal, Humanized ; Antigens, CD ; Antigens, Neoplasm ; Antineoplastic Agents ; CD52 Antigen ; CD52 protein, human ; Glycoproteins ; Alemtuzumab (3A189DH42V)
Language	English
Publishing date	2012
Publishing country	Switzerland
Document type	Case Reports ; Journal Article ; Review
ZDB-ID	80008-9
ISSN	1421-9662 ; 0001-5792
ISSN (online)	1421-9662
ISSN	0001-5792
DOI	10.1159/000336241
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Article: A Case Report of T Cell Prolymphocytic Leukemia and Kaposi Sarcoma and a Review of T Cell Prolymphocytic Leukemia

Paul, R.N. / Alizadeh, L. / Ajayi, O.I. / Karpurapu, H. / Ganesan, C. / Taddesse-Heath, L. / Aggarwal, A.

Acta Haematologica

2012 Volume 127, Issue 4, Page(s) 235–243

Institution	Division of Hematology/Oncology, Department of Medicine, and Department of Pathology, Howard University Hospital, and Division of Hematology/Oncology, Department of Internal Medicine, Veterans Affairs Medical Center and George Washington University, Washington, D.C., USA
Abstract	T cell prolymphocytic leukemia (T-PLL) is a rare mature T cell lymphoproliferative disease. It has been associated with an aggressive course, a poor response to conventional chemotherapy and a short median survival. Here we present a rare case of concurrent T-PLL and Kaposi sarcoma who achieved a complete hematologic and cytogenetic remission after a very short course of treatment with alemtuzumab. A review of T-PLL was done. In this review, clinical features, laboratory features and current therapeutic strategies of T-PLL are presented.
Keywords	T cell prolymphocytic leukemia ; Alemtuzumab ; Kaposi sarcoma ; Pentostatin ; Prolymphocytes
Language	English
Publishing date	2012-04-13
Publisher	S. Karger AG
Publishing place	Basel, Switzerland
Document type	Article
Note	Case Report
ZDB-ID	80008-9
ISSN	1421-9662 ; 0001-5792
ISSN (online)	1421-9662
ISSN	0001-5792
DOI	10.1159/000336241
Database	Karger publisher's database

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Article ; Online: CD4+ T-lymphocytes cell counts in adults with human immunodeficiency virus infection at the medical department of a tertiary health institution in Nigeria.

Ajayi, A O / Ajayi, E A / Fasakin, K A

Annals of African medicine

2009 Volume 8, Issue 4, Page(s) 257–260

Abstract: ... and 33 (37.9%) males had their CD4+ T-Lymphocytes cell counts evaluated within their first week ...

Abstract	Objectives: To evaluate the CD4+ cell counts in adults with human immunodeficiency virus (HIV) infections presenting at the medical department of the Federal Medical Centre, Ido-Ekiti, Nigeria. Methods: This study was carried out at the medical department of the Federal Medical Centre (FMC), Ido-Ekiti, Nigeria, in the period July-December 2006. FMC, Ido, was recently upgraded to serve as the only center for HIV/AIDS referral, diagnosis and treatment in Ekiti State. The center offers free antiretroviral therapy. All patients with a diagnosis of HIV/AIDS, either diagnosed at the center or referred from other hospitals, admitted to the medical department within the study period had their blood sample taken for CD4 cell counts estimation at the first visit to the center, as part of the routine workup to assess their disease status and need for antiretroviral therapy. Results: A total of 87 patients comprising of 54 (62.1%) females and 33 (37.9%) males had their CD4+ T-Lymphocytes cell counts evaluated within their first week of presentation. The total mean age of the population studied was 33.17 +/- 7.01 years. The mean age of the females was 31 +/- 5.6 years, while that of the males was 36.5 +/- 8.2 years. The difference between the mean ages of females and males was statistically significant (P = 0.0004). The female: male ratio was 1.6:1. Out of the 87 patients, 30 were referrals from other hospitals within the state. The total mean CD4+ cell count was 230.7 +/- 311.9 cells/microL. The mean CD4 cell count of females was 212.17 +/- 264.96 cells/microL, while that of males was 261.0 +/- 389.19 cells/microL. This difference was not significant (P = 0.4876). Majority of the patients (75, [86.2%]), had CD4 cell count < 350 cells/microL, comprising of 48 females and 27 males. Of the 75 patients, 57 (76%) had a CD4 cell count < 200 cells/microL (33 females vs. 24 males). Conclusion: At the time of HIV diagnosis, majority of our patients had a CD4+ cell count < 200 cells/microL. This was consistent with a relatively advanced disease. More women than men in the population were found positive for HIV. More sustained and vigorous awareness campaigns need be embarked upon in the HIV propaganda in the Ekiti State on one hand and Nigeria on the other hand to bring down this Hydra-headed monster called HIV/AIDS.
MeSH term(s)	Adult ; Age Factors ; Anti-HIV Agents/therapeutic use ; CD4 Lymphocyte Count ; CD4-Positive T-Lymphocytes/immunology ; Female ; Flow Cytometry ; HIV Infections/diagnosis ; HIV Infections/drug therapy ; HIV Infections/immunology ; HIV Infections/virology ; HIV-1 ; Hospital Departments ; Hospitals, Public ; Humans ; Male ; Nigeria ; Prognosis ; Sex Factors
Chemical Substances	Anti-HIV Agents
Language	English
Publishing date	2009-10
Publishing country	India
Document type	Evaluation Studies ; Journal Article
ZDB-ID	2165792-0
ISSN	0975-5764 ; 1596-3519
ISSN (online)	0975-5764
ISSN	1596-3519
DOI	10.4103/1596-3519.59581
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Association between Alanine Aminotransferase, Hypertension and Obesity in Nigerians.

Dele-Ojo, B F / Dada, S A / Fadare, J O / Ajayi, D D / Ajayi, E A / Raimi, T H / Ajayi, A O

West African journal of medicine

2024 Volume 40, Issue 12, Page(s) 1291–1297

Abstract: Background: Cardiovascular diseases (CVDs) are the leading causes of morbidity and mortality worldwide. Alanine aminotransferase (ALT) is associated with hypertension and obesity.: Objectives: To determine the association between ALT within the ... ...

Abstract	Background: Cardiovascular diseases (CVDs) are the leading causes of morbidity and mortality worldwide. Alanine aminotransferase (ALT) is associated with hypertension and obesity. Objectives: To determine the association between ALT within the reference range with hypertension and obesity. Methods: This study utilized the data of a cross-sectional health survey involving 558 adult participants. Anthropometry, blood pressure, and plasma glucose were determined with standard protocols. Quartiles of log-transformed ALT were generated and the association with obesity/hypertension was determined with ANOVA and regression analysis. Results: There were 205 (36.7%) men. The mean fasting plasma glucose (FPG) of all participants was 4.7 (1.6) mmol/L. In men, there was a positive correlation between ALT and body mass index (BMI) (r=0.148; p=0.038), waist circumference (WC) (r=0.166; p=0.020), and waist-to-height-ratio (WHtR) (r=0.163; p=0.021). No correlation was observed between ALT and anthropometric indices in women, or with blood pressure indices in both genders. In men, only WHtR (p for trend, 0.045) was significantly associated with ALT quartiles, whereas in women, only WC (p for trend, 0.028) was significantly associated with ALT quartiles. In men, compared to 1st quartile, the OR for general obesity of the 4th quartile of Log ALT was 2.662 (95% CI 1.219 - 5.816; p=0.014). In women, the OR for hypertension of the 3rd quartile of Log ALT versus the 1st quartile was 1.955 (95% CI 0.694 - 2.416; p=0.041). Log ALT did not predict hypertension and obesity in men and women, respectively. Conclusions: The risks of obesity and hypertension increase as the ALT level increases within the normal ALT range. People with normal levels of ALT in the upper limits need to be evaluated for metabolic disorders.
MeSH term(s)	Adult ; Female ; Humans ; Male ; Alanine Transaminase ; Blood Glucose ; Cross-Sectional Studies ; Hypertension/epidemiology ; Obesity/epidemiology ; West African People
Chemical Substances	Alanine Transaminase (EC 2.6.1.2) ; Blood Glucose
Language	English
Publishing date	2024-01-19
Publishing country	Nigeria
Document type	Journal Article
ZDB-ID	1132088-6
ISSN	0189-160X
ISSN	0189-160X
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Article ; Online: A core of cell wall proteins functions in wall integrity responses in

Ajayi, Oyeyemi / Zelinsky, Ellen / Anderson, Charles T

Plant direct

2024 Volume 8, Issue 4, Page(s) e579

Abstract: Cell walls surround all plant cells, and their composition and structure are tightly regulated to maintain cellular and organismal homeostasis. In response to wall damage, the cell wall integrity (CWI) system is engaged to ameliorate effects on plant ... ...

Abstract	Cell walls surround all plant cells, and their composition and structure are tightly regulated to maintain cellular and organismal homeostasis. In response to wall damage, the cell wall integrity (CWI) system is engaged to ameliorate effects on plant growth. Despite the central role CWI plays in plant development, our current understanding of how this system functions at the molecular level is limited. Here, we investigated the transcriptomes of etiolated seedlings of mutants of
Language	English
Publishing date	2024-04-02
Publishing country	England
Document type	Journal Article
ISSN	2475-4455
ISSN (online)	2475-4455
DOI	10.1002/pld3.579
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Article: Effect of allergen challenge on the percentage of natural killer T cells in patients with atopic asthma.

Rock, Michael / Yoder, Sandra / Hoskins, Aimee / Ajayi, Wilfred U / Ajayi, Wiktor / Sheller, James R / Dworski, Ryszard

Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology

2009 Volume 102, Issue 5, Page(s) 432–437

Abstract: Background: Invariant natural killer T (iNKT) cells produce cytokines that can influence ... T cells remained unchanged 24 hours after SAC (0.035% [0.01%] vs 0.049% [0.02%]; n = 8; P = .50). Likewise ...

Abstract	Background: Invariant natural killer T (iNKT) cells produce cytokines that can influence the immune response to infection or allergen. Controversy surrounds their role in exacerbations of human atopic asthma. Objectives: To determine the effect of allergen challenge on iNKT cells' mobilization to the airways and blood and to establish the relationship between airway iNKT cells and bronchial sensitivity to methacholine and allergen in patients with atopic asthma. Methods: We performed flow cytometry analysis for the iNKT cell receptor Va24 and V311 on bronchoalveolar lavage (BAL) cells at baseline and 24 hours after segmental antigen challenge (SAC) (n = 8) and on peripheral blood mononuclear cells (PBMCs) at baseline and 6 to 7 hours after inhaled allergen (n = 10). Challenges were performed using standardized protein allergens to which the participants were sensitive. Results: The number of BAL eosinophils increased 24 hours after SAC. The low mean (SEM) baseline percentage of iNKT cells in the population of BAL CD4' T cells remained unchanged 24 hours after SAC (0.035% [0.01%] vs 0.049% [0.02%]; n = 8; P = .50). Likewise, the mean (SEM) percentage of iNKT cells in PBMCs was unchanged after inhaled allergen provocation (0.068% [0.033%] vs 0.057% [0.026%]; n = 10; P = .10). No correlation was found between iNKT cells in BAL and the sensitivity to inhaled methacholine or allergen. Conclusions: The percentages of both BAL and peripheral blood iNKT cells did not increase during allergen provoked asthmatic responses. Determination of iNKT cells in airway biopsy specimens would allow conclusively ruling against mobilization of iNKT cells in allergen-induced asthma exacerbation in humans.
MeSH term(s)	Adult ; Allergens/immunology ; Asthma/immunology ; Asthma/physiopathology ; Blood Cells/cytology ; Bronchial Provocation Tests ; Bronchoalveolar Lavage Fluid/cytology ; Eosinophils/cytology ; Female ; Forced Expiratory Volume/drug effects ; Forced Expiratory Volume/immunology ; Humans ; Lymphocyte Count ; Male ; Methacholine Chloride/pharmacology ; Natural Killer T-Cells/cytology ; Natural Killer T-Cells/immunology ; Neutrophils/cytology ; Young Adult
Chemical Substances	Allergens ; Methacholine Chloride (0W5ETF9M2K)
Language	English
Publishing date	2009-04-03
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural
ZDB-ID	1228189-x
ISSN	1534-4436 ; 1081-1206 ; 0003-4738
ISSN (online)	1534-4436
ISSN	1081-1206 ; 0003-4738
DOI	10.1016/s1081-1206(10)60517-0
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Article ; Online: Baseline CD4+ T lymphocyte cell counts, hepatitis B and C viruses seropositivity in adults with Human Immunodeficiency Virus infection at a tertiary hospital in Nigeria.

Adekunle, Ajayi Ebenezer / Oladimeji, Ajayi Akande / Temi, Adegun Patrick / Adeseye, Ajayi Iyiade / Akinyeye, Ojo Abiodun / Taiwo, Raimi Hussean

The Pan African medical journal

2011 Volume 9, Page(s) 6

Abstract: ... CD4+ T- Lymphocytes cell count of those who had HBsAg negative status compared to those who had HBsAg ... positive status. Two (0.7%) of the patients had positive serum anti HCV antibodies. The CD4+ T ... 71.8%) had a CD4+ T- Lymphocytes cell count < 350 cells/µl.: Conclusion: At the time ...

Abstract	Background: Ekiti State of Nigeria is known to have the lowest prevalence of HIV in Nigeria. University Teaching Hospital (UTH), Ado Ekiti was recently upgraded to serve as one of the three centres for HIV/AIDS referral, diagnosis and treatment in Ekiti State. We evaluated the baseline immunologic and biochemical parameters of patients presenting at the ART clinic of University Teaching Hospital, Ado Ekiti, Ekiti State. Methods: All HIV seropositive patients not yet on antiretroviral therapy, who presented at the ART Clinic within the study period had at the first visit to the clinic, their blood sample taken for CD4 cell counts estimation, HBsAg and anti- HCV screening, ALT, AST as well as hemoglobin estimation as part of the routine workup to assess their disease health status and need for antiretroviral therapy. Statistical significance was taken as p< 0.05. Results: A total of 273 patients comprising 79 (28.9%) males and 194 (71.1%) females were included in the study (F:M = 2.46: 1). The mean age of the study population was 36.21 ± 10.20 years with mean age of males (39.52 ± 9.95 years) significantly higher than females (34.88 ± 10.02; p=0.001). The overall prevalence of HBsAg in the study population was 6.6% with a sex specific prevalence of 8.1% and 6% for males and females, respectively. No statistically significance difference in the mean serum alanine transaminase, serum aspartate transaminase, hemoglobin and CD4+ T- Lymphocytes cell count of those who had HBsAg negative status compared to those who had HBsAg positive status. Two (0.7%) of the patients had positive serum anti HCV antibodies. The CD4+ T- Lymphocytes cell count ranged between 5 - 1050 cells/µl with a mean of 286.19 ± 233.31 cells/µl. The majority of patients (71.8%) had a CD4+ T- Lymphocytes cell count < 350 cells/µl. Conclusion: At the time of presentation, majority of our patients had a CD4+ T- Lymphocytes cell count less than 350 cells/µl consistent with significant immune-suppression. More sustained and vigorous awareness campaigns still need to be done in Ekiti State to diagnose this disease early. There is also a need to accelerate the integration of hepatitis B virus screening and treatment programme into HIV/AIDS programme because of the morbidity and mortality implication of HBV and HIV co-infection.
MeSH term(s)	Adolescent ; Adult ; Aged ; CD4 Lymphocyte Count ; Female ; HIV Infections/complications ; HIV Infections/immunology ; HIV Seropositivity/immunology ; Hepatitis B/complications ; Hepatitis B/epidemiology ; Hepatitis B/immunology ; Hepatitis B Surface Antigens/blood ; Hepatitis C/complications ; Hepatitis C/epidemiology ; Hepatitis C/immunology ; Hepatitis C Antibodies/blood ; Hospitals ; Humans ; Male ; Middle Aged ; Nigeria/epidemiology ; Prevalence ; Seroepidemiologic Studies ; Young Adult
Chemical Substances	Hepatitis B Surface Antigens ; Hepatitis C Antibodies
Language	English
Publishing date	2011-05-21
Publishing country	Uganda
Document type	Journal Article ; Research Support, U.S. Gov't, P.H.S.
ZDB-ID	2514347-5
ISSN	1937-8688 ; 1937-8688
ISSN (online)	1937-8688
ISSN	1937-8688
DOI	10.4314/pamj.v9i1.71178
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Article ; Online: Abdominal obesity, serum estradiol and cardiovascular risk among Nigerian postmenopausal women: a cross-sectional study.

Lewechi-Uke, Omolara T / Ajayi, Ikeoluwapo O / Akinyemi, Joshua O

African health sciences

2024 Volume 23, Issue 3, Page(s) 90–98

Abstract: Background: Rates of cardiovascular (CV) disease mortality is usually higher in men but this equalizes with that of women following menopause.: Objectives: This was to determine the contribution of abdominal obesity and estradiol to cardiovascular ... ...

Abstract	Background: Rates of cardiovascular (CV) disease mortality is usually higher in men but this equalizes with that of women following menopause. Objectives: This was to determine the contribution of abdominal obesity and estradiol to cardiovascular risk in postmenopausal women (PMW) as well as estimate their CV risk profile. Methods: 271 consenting PMW were recruited consecutively into this cross-sectional hospital-based study. Data relating to their socio-demography, blood pressure and anthropometry was obtained and laboratory analysis of lipid profile and serum estradiol was done. Cardiovascular risk of participants was estimated using standardized calculators. Results: Mean age of participants was 57.8±5.5 years. Significant correlation existed between each of triglyceride (Positive), High Density Lipoprotein (negative) and Waist-Hip-Ratio (WHR) (p=0.001 and 0.000 respectively). Hypertension and dyslipidaemia were significantly associated with WHR (p=0.01 and 0.031 respectively). Significant negative correlation existed between CV risk profile and serum estradiol (rs = -0.140, p = 0.028). Ten-unit increase in WHR was associated with two-fold risk of hypertension (OR> 1.73, C.I.= 1.13-2.66). A unit change in age was associated with 0.61 increase in TC. Conclusion: Abdominal obesity and serum estradiol significantly influence cardio-metabolic risk. Newer risk calculator which incorporates factors peculiar to women such as serum E2 is hereby recommended.
MeSH term(s)	Male ; Humans ; Female ; Middle Aged ; Cross-Sectional Studies ; Obesity, Abdominal/epidemiology ; Cardiovascular Diseases/epidemiology ; Risk Factors ; Postmenopause ; Body Mass Index ; Obesity/complications ; Hypertension/epidemiology ; Hypertension/complications ; Heart Disease Risk Factors ; Estradiol
Chemical Substances	Estradiol (4TI98Z838E)
Language	English
Publishing date	2024-02-03
Publishing country	Uganda
Document type	Journal Article
ZDB-ID	2240308-5
ISSN	1729-0503 ; 1680-6905
ISSN (online)	1729-0503
ISSN	1680-6905
DOI	10.4314/ahs.v23i3.12
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Article: Antioxidant and antilipidemic action of ketogenic diet and tomato powder mix in high sugar and fat fed Harwich fruit flies.

Kayode, Omowumi T / Afolabi, Olatayo A / Ajayi, Gabriel O

Heliyon

2023 Volume 9, Issue 10, Page(s) e20411

Abstract: Numerous studies have demonstrated the role of oxidative stress in metabolic disorders which presents as a major global problem. The antioxidant properties of the tomato fruit and the ketogenic diet has likewise been established by different authors. ... ...

Abstract	Numerous studies have demonstrated the role of oxidative stress in metabolic disorders which presents as a major global problem. The antioxidant properties of the tomato fruit and the ketogenic diet has likewise been established by different authors. This study uses a fruit fly model to examine the synergistic effect of a ketogenic diet and tomato powder mix on biochemical alterations induced by the High-Fat Diet (HFD) and the High-Sugar Diet (HSD). Six groups of male fruit flies consisting of fifty flies per vial were administered Normal Diet (ND), High-Fat Diet (HFD), High Sugar Diet (HSD), Ketogenic Diet (KD), Tomato Powder-mix (TP), and HSD + HFD, for ten days. Further treatment of KD and TP was administered to group six vials to constitute groups seven to nine: HSD + HFD + KD, HSD + HFD + TP, and HSD + HFD + KD + TP for another five days. Biochemical parameters of oxidative stress were analyzed in the fly homogenates using standard procedures. There were significant increases (P < 0.05) in the concentration of malondialdehyde, total cholesterol, LDL-Cholesterol, Triglycerides, atherogenic index, nitric oxide, total weight gained, and a significant decrease (p < 0.05) in levels of catalase and HDL-Cholesterol in flies treated with HF and HS diets. Further administration of KD and TP to the flies for five days reversed most of the parameters to near control values. The KD diet combination with TP however gave the best ameliorative changes. The dietary model may therefore be effective as adjuvant therapy for the management of metabolic disorders developed and made progressive by oxidative stress and hyperlipidemia.
Language	English
Publishing date	2023-09-24
Publishing country	England
Document type	Journal Article
ZDB-ID	2835763-2
ISSN	2405-8440
ISSN	2405-8440
DOI	10.1016/j.heliyon.2023.e20411
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Article ; Online: Co-infection of Helicobacter Pylori and intestinal parasites in children of selected Low-income communities in Lagos State, Nigeria.

Aniekwe, O / Jolaiya, T / Ajayi, A / Adeleye, I A / Gerhard, M / Smith, S I

Parasitology international

2024 Volume 101, Page(s) 102896

Abstract: Helicobacter pylori and intestinal parasites cause gastrointestinal diseases with a high prevalence in children in resource limited developing countries. There is paucity of information in Nigeria on co-infection of H. pylori and intestinal parasites. ... ...

Abstract	Helicobacter pylori and intestinal parasites cause gastrointestinal diseases with a high prevalence in children in resource limited developing countries. There is paucity of information in Nigeria on co-infection of H. pylori and intestinal parasites. The study was conducted to determine the prevalence of H. pylori and parasite co-infection in children from selected low-income communities in Lagos, Nigeria. Fecal samples were collected from 151 healthy children aged ≤11 years across six low-income communities in Lagos. H. pylori was detected using stool antigen test and conventional PCR assay, intestinal parasites were detected using formol-ether concentration and nested PCR assay. Structured questionnaires were administered to parents and legal guardians of the children by an interviewer to collect relevant data on demographic and lifestyle factors. The prevalence of H. pylori was 31.79% (48), with a higher prevalence in children aged 2-3 years. The prevalence of intestinal parasites was 21.19% (32) with the lowest frequency found in children aged 8-9 years. The parasites detected include: A. lumbricoides (10.6%), G. intestinalis (7.3%), hookworm (1.99%), E. histolytica (0.66%), S. mansoni (0.66%). There was co-infection prevalence of 10.6% (16) which was associated with the parasites: G. intestinalis (7.3%) and A. lumbricoides (3.97%). Polyparasitism with G. intestinalis and A. lumbricoides was reported in 2 children infected with H. pylori. This study which is the first reported in Lagos established a low prevalence of H. pylori and intestinal parasite co-infection in children and provides better understanding of the epidemiology of H. pylori infection associated with intestinal parasites in Nigeria.
Language	English
Publishing date	2024-04-21
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	1363151-2
ISSN	1873-0329 ; 1383-5769
ISSN (online)	1873-0329
ISSN	1383-5769
DOI	10.1016/j.parint.2024.102896
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