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  1. Article: Application and Uses of the Rubber Dam.

    Lynch, H T

    The American journal of dental science

    2019  Volume 23, Issue 1, Page(s) 34–37

    Language English
    Publishing date 2019-02-12
    Publishing country United States
    Document type Journal Article
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Children's Play-Work Occupation Continuum: Play-Based Occupational Therapy, Play Therapy and Playwork.

    Brown, Ted / Lynch, Helen

    Canadian journal of occupational therapy. Revue canadienne d'ergotherapie

    2022  Volume 90, Issue 3, Page(s) 249–256

    Abstract: Introduction: ...

    Abstract Introduction:
    MeSH term(s) Adult ; Humans ; Child ; Occupational Therapy ; Play Therapy ; Occupations ; Activities of Daily Living ; Occupational Therapists
    Language English
    Publishing date 2022-10-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 417302-8
    ISSN 1911-9828 ; 0008-4174 ; 0315-1026
    ISSN (online) 1911-9828
    ISSN 0008-4174 ; 0315-1026
    DOI 10.1177/00084174221130165
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Remote learning, telehealth, tele-early intervention, school-based telerehabilitation: The impact of the Covid-19 pandemic on children's occupational repertoires and routines.

    Brown, Ted / Lynch, Helen

    Australian occupational therapy journal

    2022  Volume 69, Issue 2, Page(s) 113–116

    MeSH term(s) COVID-19/epidemiology ; Child ; Humans ; Occupational Therapy ; Pandemics ; Telemedicine ; Telerehabilitation
    Language English
    Publishing date 2022-03-16
    Publishing country Australia
    Document type Editorial
    ZDB-ID 604554-6
    ISSN 1440-1630 ; 0045-0766
    ISSN (online) 1440-1630
    ISSN 0045-0766
    DOI 10.1111/1440-1630.12798
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  4. Article ; Online: Environmental Qualities That Enhance Outdoor Play in Community Playgrounds from the Perspective of Children with and without Disabilities: A Scoping Review.

    Morgenthaler, Thomas / Schulze, Christina / Pentland, Duncan / Lynch, Helen

    International journal of environmental research and public health

    2023  Volume 20, Issue 3

    Abstract: For children, playgrounds are important environments. However, children's perspectives are often not acknowledged in playground provision, design, and evaluation. This scoping review aimed to summarize the users' (children with and without disabilities) ... ...

    Abstract For children, playgrounds are important environments. However, children's perspectives are often not acknowledged in playground provision, design, and evaluation. This scoping review aimed to summarize the users' (children with and without disabilities) perspectives on environmental qualities that enhance their play experiences in community playgrounds. Published peer-reviewed studies were systematically searched in seven databases from disciplines of architecture, education, health, and social sciences; 2905 studies were screened, and the last search was performed in January 2023. Included studies (
    MeSH term(s) Play and Playthings ; Data Accuracy ; Social Sciences ; Educational Status
    Language English
    Publishing date 2023-01-18
    Publishing country Switzerland
    Document type Systematic Review ; Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 2175195-X
    ISSN 1660-4601 ; 1661-7827
    ISSN (online) 1660-4601
    ISSN 1661-7827
    DOI 10.3390/ijerph20031763
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  5. Article ; Online: Green Sea Turtles (Chelonia mydas) Accumulate Heavy Metals Near a Former Skeet Shooting Range in Kailua, O'ahu, Hawai'i.

    Shaw, Katherine R / Balazs, George H / Jones, T Todd / Lynch, Harry W / Liu, Jing / Cobb, George P / Klein, David M / Lynch, Jennifer M

    Environmental toxicology and chemistry

    2023  Volume 42, Issue 5, Page(s) 1109–1123

    Abstract: The present study determined if green sea turtles (Chelonia mydas) in Kailua Bay, Oahu, in the Hawaiian Islands have elevated blood and scute lead (Pb), arsenic (As), and antimony (Sb) concentrations resulting from lead deposition at a historic skeet ... ...

    Abstract The present study determined if green sea turtles (Chelonia mydas) in Kailua Bay, Oahu, in the Hawaiian Islands have elevated blood and scute lead (Pb), arsenic (As), and antimony (Sb) concentrations resulting from lead deposition at a historic skeet shooting range. Blood and scute samples were collected and analyzed for Pb, As, and Sb via inductively coupled plasma-mass spectrometry. Prey, water, and sediment samples were also analyzed. Turtle samples in Kailua Bay (45) have blood Pb concentrations (328 ± 195 ng/g) greater than a reference population (Howick Group of Islands, 29.2 ± 17.1 ng/g). Compared with other green turtle populations, only turtles in Oman, Brazil, and San Diego, CA have blood Pb concentrations greater than turtles in Kailua Bay. The estimated daily exposure of Pb from algae sources in Kailua Bay (0.12 mg/kg/day) was significantly lower than the no observed adverse effect level (100 mg/kg) of red-eared slider turtles. However, the chronic effects of Pb on sea turtles is poorly understood and continued monitoring of this population will increase our understanding of the Pb and As loads of sea turtles in Kailua Bay. Environ Toxicol Chem 2023;42:1109-1123. © 2023 SETAC. This article has been contributed to by U.S. Government employees and their work is in the public domain in the USA.
    MeSH term(s) Animals ; Turtles ; Hawaii ; Lead/analysis ; Water Pollutants, Chemical/analysis ; Metals, Heavy/analysis ; Arsenic/analysis
    Chemical Substances Lead (2P299V784P) ; Water Pollutants, Chemical ; Metals, Heavy ; Arsenic (N712M78A8G)
    Language English
    Publishing date 2023-04-07
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 46234-2
    ISSN 1552-8618 ; 0730-7268
    ISSN (online) 1552-8618
    ISSN 0730-7268
    DOI 10.1002/etc.5601
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  6. Article ; Online: Change in Neuropsychological Test Performance Seen in a Longitudinal Study of Patients With Post-acute Sequelae of COVID-19: A 6-Month Follow-up Study.

    Lynch, Sean T / Dornbush, Rhea / Shahar, Sivan / Mansour, Rayah / Klepacz, Lidia / Primavera, Louis H / Ferrando, Stephen J

    Journal of the Academy of Consultation-Liaison Psychiatry

    2024  

    Abstract: Background: Post-acute sequelae of COVID-19 may include physical, psychiatric, and neurocognitive symptoms. Few studies of cognitive symptoms have been longitudinal, with many following participants briefly after infection and relying on subjective ... ...

    Abstract Background: Post-acute sequelae of COVID-19 may include physical, psychiatric, and neurocognitive symptoms. Few studies of cognitive symptoms have been longitudinal, with many following participants briefly after infection and relying on subjective complaints, screening instruments, or computerized testing. This group previously reported diminished neuropsychological (NP) test performance in over half of 60 individuals tested in-person 7 months post-COVID-19, particularly those seeking care for cognitive complaints. The current study describes the initial and 6-month follow-up results of an expanded cohort of 75 participants.
    Objective: To measure longitudinal changes in neuropsychological test performance, as well as medical and psychiatric changes, post-COVID-19.
    Methods: Participants underwent NP, psychiatric, and medical assessments approximately 7 months after acute COVID-19 infection. Sixty-three (84%) returned approximately 6 months later for repeat evaluation.
    Results: At the initial visit, 29 (38.7%) met criteria for low NP performance, and 16 (21.3%) met criteria for extremely low NP performance. At 6-month follow-up, several NP domains that were significantly below normative values at the initial visit were no longer abnormal, with the exception of language. Only measures of delayed memory and fatigue showed significant improvements between the 2 time points.
    Conclusions: A substantial proportion of individuals recovered from acute COVID-19 infection have persistent neuropsychiatric symptoms over 1 year after infection. While the overall sample in this study showed some improvement in NP test performance relative to norms, only fatigue and delayed memory improved significantly between times 1 and 2. No individual declined in NP test performance, though relatively few individuals made significant clinical improvement, indicating the need for serial neuropsychiatric assessment and treatment supports. Longitudinal follow-up of this cohort is in progress.
    Language English
    Publishing date 2024-01-01
    Publishing country Netherlands
    Document type Journal Article
    ISSN 2667-2960
    ISSN (online) 2667-2960
    DOI 10.1016/j.jaclp.2023.12.005
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  7. Article ; Online: Isolated soft tissue mass of the finger as the first presentation of oligometastatic renal cell carcinoma.

    Hopkins, David T / Waters, Darragh / Manecksha, Rustom P / Lynch, Thomas H

    BMJ case reports

    2022  Volume 15, Issue 5

    Abstract: A man in his 70s was referred to plastic surgery with a suspected foreign body in the pulp of his right index finger. An excisional biopsy was performed for a presumed foreign body granuloma. Histology revealed metastatic renal cell carcinoma (mRCC). CT ... ...

    Abstract A man in his 70s was referred to plastic surgery with a suspected foreign body in the pulp of his right index finger. An excisional biopsy was performed for a presumed foreign body granuloma. Histology revealed metastatic renal cell carcinoma (mRCC). CT imaging demonstrated a 7.4 cm heterogeneous mass arising from the upper pole of the left kidney consistent with primary renal malignancy, in addition to a 9 mm lung nodule. He underwent an uncomplicated left laparoscopic cytoreductive nephrectomy and made a satisfactory recovery. To our knowledge, this is the first reported case of primary mRCC presenting with digital soft tissue metastasis. Cytoreductive nephrectomy with metastasectomy is the preferred management for mRCC where feasible. For unfavourable mRCC cases, first-line systemic therapy is indicated. Adjuvant systemic therapy in mRCC is currently limited to clinical trials, though promising data emerging on the use of pembrolizumab may herald a future shift in practice.
    MeSH term(s) Carcinoma, Renal Cell/diagnostic imaging ; Carcinoma, Renal Cell/pathology ; Carcinoma, Renal Cell/surgery ; Cytoreduction Surgical Procedures/methods ; Humans ; Kidney Neoplasms/diagnostic imaging ; Kidney Neoplasms/pathology ; Kidney Neoplasms/surgery ; Male ; Metastasectomy ; Nephrectomy/methods
    Language English
    Publishing date 2022-05-17
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr-2021-248718
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  8. Article ; Online: Fentanyl overdose: Temporal effects and prognostic factors in SKH1 mice.

    Newman, Mackenzie / Lynch, Cayla / Connery, Heather / Goldsmith, William / Nurkiewicz, Timothy / Raylman, Raymond / Boyd, Jonathan

    Basic & clinical pharmacology & toxicology

    2024  Volume 134, Issue 4, Page(s) 460–471

    Abstract: Fentanyl exposure and overdose are growing concerns in public health and occupational safety. This study aimed to establish parameters of fentanyl lethality in SKH1 mice for future overdose research. Lethality was determined using the up-down procedure, ... ...

    Abstract Fentanyl exposure and overdose are growing concerns in public health and occupational safety. This study aimed to establish parameters of fentanyl lethality in SKH1 mice for future overdose research. Lethality was determined using the up-down procedure, with subjects monitored post-administration using pulse oximetry (5 min) and then whole-body plethysmography (40 min). Following the determination of subcutaneous dose-response, [18F]Fluorodeoxyglucose positron emission tomography (
    MeSH term(s) Humans ; Animals ; Mice ; Fluorodeoxyglucose F18/therapeutic use ; Prognosis ; Fentanyl/toxicity ; Positron-Emission Tomography ; Drug Overdose/drug therapy ; Analgesics, Opioid/therapeutic use
    Chemical Substances Fluorodeoxyglucose F18 (0Z5B2CJX4D) ; Fentanyl (UF599785JZ) ; Analgesics, Opioid
    Language English
    Publishing date 2024-01-29
    Publishing country England
    Document type Journal Article
    ZDB-ID 2134679-3
    ISSN 1742-7843 ; 1742-7835
    ISSN (online) 1742-7843
    ISSN 1742-7835
    DOI 10.1111/bcpt.13984
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  9. Article ; Online: The role of surgical disconnection for posterior fossa pial arteriovenous fistulas and dural fistulas with pial supply: an illustrative case series.

    Golub, Danielle / Lynch, Daniel G / Mehta, Shyle H / Donaldson, Hayley / Shah, Kevin A / White, Timothy G / Quach, Eric T / Papadimitriou, Kyriakos / Kuffer, Alexander F / Woo, Henry H / Link, Thomas W / Patsalides, Athos / Dehdashti, Amir R

    Neurosurgical review

    2024  Volume 47, Issue 1, Page(s) 189

    Abstract: Background: Pial arteriovenous fistulas (pAVFs) are rare vascular malformations characterized by high-flow arteriovenous shunting involving a cortical arterial supply directly connecting to venous drainage without an intermediate nidus. Dural ... ...

    Abstract Background: Pial arteriovenous fistulas (pAVFs) are rare vascular malformations characterized by high-flow arteriovenous shunting involving a cortical arterial supply directly connecting to venous drainage without an intermediate nidus. Dural arteriovenous fistulas (dAVFs) can infrequently involve additional pial feeders which can introduce higher flow shunting and increase the associated treatment risk. In the posterior fossa, arteriovenous fistula (AVF) angioarchitecture tends to be particularly complex, involving either multiple arterial feeders-sometimes from both dural and pial origins-or small caliber vessels that are difficult to catheterize and tend to be intimately involved with functionally critical brainstem or upper cervical cord structures. Given their rarity, published experience on microsurgical or endovascular treatment strategies for posterior fossa pAVFs and dAVFs with pial supply remains limited.
    Methods: Retrospective chart review from 2019-2023 at a high-volume center identified six adult patients with posterior fossa pAVFs that were unable to be fully treated endovascularly and required microsurgical disconnection. These cases are individually presented with a technical emphasis and supported by comprehensive angiographic and intraoperative images.
    Results: One vermian (Case 1), three cerebellopontine angle (Cases 2-4) and two craniovertebral junction (Cases 5-6) posterior fossa pAVFs or dAVFs with pial supply are presented. Three cases involved mixed dural and pial arterial supply (Cases 1, 4, and 6), and one case involved a concomitant microAVM (Case 2). Endovascular embolization was attempted in four cases (Cases 1-4): The small caliber and tortuosity of the main arterial feeder prevented catheterization in two cases (Cases 1 and 3). Partial embolization was achieved in Cases 2 and 4. In Cases 5 and 6, involvement of the lateral spinal artery or anterior spinal artery created a prohibitive risk for endovascular embolization, and surgical clip ligation was pursued as primary management. In all cases, microsurgical disconnection resulted in complete fistula obliteration without evidence of recurrence on follow-up imaging (mean follow-up 27.1 months). Two patients experienced persistent post-treatment sensory deficits without significant functional limitation.
    Conclusions: This illustrative case series highlights the technical difficulties and anatomical limitations of endovascular management for posterior fossa pAVFs and dAVFs with pial supply and emphasizes the relative safety and utility of microsurgical disconnection in this context. A combined approach involving partial preoperative embolization-when the angioarchitecture is permissive-can potentially decrease surgical morbidity. Larger studies are warranted to better define the role for multimodal intervention and to assess associated long-term AVF obliteration rates in the setting of pial arterial involvement.
    MeSH term(s) Humans ; Male ; Female ; Middle Aged ; Central Nervous System Vascular Malformations/surgery ; Aged ; Pia Mater/blood supply ; Pia Mater/surgery ; Retrospective Studies ; Adult ; Arteriovenous Fistula/surgery ; Cranial Fossa, Posterior/surgery ; Neurosurgical Procedures/methods ; Embolization, Therapeutic/methods ; Intracranial Arteriovenous Malformations/surgery
    Language English
    Publishing date 2024-04-25
    Publishing country Germany
    Document type Journal Article ; Case Reports
    ZDB-ID 6907-3
    ISSN 1437-2320 ; 0344-5607
    ISSN (online) 1437-2320
    ISSN 0344-5607
    DOI 10.1007/s10143-024-02407-y
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  10. Article ; Online: Physical activity and pain in people with and without cancer.

    Swain, Christopher T V / Masters, Matthew / Lynch, Brigid M / Patel, Alpa V / Rees-Punia, Erika

    Cancer

    2024  

    Abstract: ... for adults with (odds ratio [OR], 0.84 [≥15 metabolic equivalent of task (MET) h/week vs. <7.5 MET h/week ...

    Abstract Background: Performing physical activity may provide analgesic benefit, although this effect is more established for noncancer pain rather than cancer pain. The relationship between physical activity and pain outcomes in adults with and without a history of cancer was examined.
    Methods: Totals of 51,439 adults without a cancer history and 10,651 adults with a cancer history from the Cancer Prevention Study II Nutrition Cohort were included. Exposures included self-reported moderate to vigorous physical activity (MVPA) as well as 2-year change in MVPA. Pain outcomes included pain intensity (primary outcome) and analgesic use (secondary outcome).
    Results: MVPA was inversely associated with pain intensity for adults with (odds ratio [OR], 0.84 [≥15 metabolic equivalent of task (MET) h/week vs. <7.5 MET h/week]; 95% confidence interval [CI], 0.76-0.93) and without (OR, 0.79; 95% CI, 0.75-0.82) a history of cancer. Compared to remaining inactive, participants who became sufficiently active (cancer: OR, 0.76; 95% CI, 0.68-0.86; no cancer: OR, 0.73; 95% CI, 0.69-0.77), became inactive (cancer: OR, 0.79; 95% CI, 0.71-0.88; no cancer: OR, 0.84; 95% CI, 0.80-0.89), or remained sufficiently active (cancer: OR, 0.66; 95% CI, 0.60-0.72; no cancer: OR, 0.62; 95% CI, 0.60-0.65) also reported less pain. Physical activity was not related to analgesic use.
    Conclusions: The relationship between physical activity and pain intensity was not substantially different between people with and without a history of cancer. Cancer survivors who perform more activity, or who increase their activity, may experience less pain than cancer survivors who consistently perform less.
    Plain language summary: People who have had cancer often experience ongoing pain. Being physically active may help reduce the intensity of the pain they experience.
    Language English
    Publishing date 2024-02-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1429-1
    ISSN 1097-0142 ; 0008-543X ; 1934-662X
    ISSN (online) 1097-0142
    ISSN 0008-543X ; 1934-662X
    DOI 10.1002/cncr.35208
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