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  1. Article: Electroencephalographic findings in asymptomatic relatives of patients with juvenile myoclonic epilepsy: relationship with the degree of kinship.

    Martínez-Juárez, Iris E / Jara-Prado, Aurelio / Ochoa-Morales, Adriana / Castro-Veloz, Nancy / Santos-Peyret, Andrea / Armenta-Báez, Jimena / Sebastián-Díaz, Mario A

    Gaceta medica de Mexico

    2022  Volume 157, Issue 4, Page(s) 411–415

    Abstract: Introduction: A prevalence of 1 to 71% of electroencephalogram (EEG) abnormalities has been reported in asymptomatic relatives of patients with juvenile myoclonic epilepsy (JME).: Objective: To determine the frequency of EEG abnormalities in ... ...

    Title translation Hallazgos electroencefalográficos en familiares asintomáticos de pacientes con epilepsia mioclónica juvenil: su relación con el grado de parentesco.
    Abstract Introduction: A prevalence of 1 to 71% of electroencephalogram (EEG) abnormalities has been reported in asymptomatic relatives of patients with juvenile myoclonic epilepsy (JME).
    Objective: To determine the frequency of EEG abnormalities in asymptomatic relatives of patients with JME according to the degree of kinship.
    Methods: Prospective, analytical study. First-, second, and third-degree relatives of patients with JME who agreed to participate and signed informed consent were included. The analysis was descriptive, bivariate.
    Results: 209 asymptomatic relatives were included, out of which 115 (55%) were females and 94 (45%) were males, with a mean age of 35.9 ± 16.9 (range between 6 and 73 years). Forty-four (21.1%) relatives had abnormal EEGs. First-degree relatives (12%) had abnormalities more frequently in comparison with second- and third-degree relatives (p = 0.007).
    Conclusions: EEG abnormalities were observed in one third of asymptomatic relatives. It is important to highlight that there were more alterations among first-degree relatives. In the future, these findings might enable for the risk of clinically developing the disease to be estimated and for genetic counseling to be provided.
    MeSH term(s) Adolescent ; Adult ; Aged ; Child ; Electroencephalography ; Female ; Humans ; Male ; Middle Aged ; Myoclonic Epilepsy, Juvenile/diagnosis ; Myoclonic Epilepsy, Juvenile/epidemiology ; Myoclonic Epilepsy, Juvenile/genetics ; Prevalence ; Prospective Studies ; Young Adult
    Language English
    Publishing date 2022-02-08
    Publishing country Mexico
    Document type Journal Article
    ZDB-ID 425456-9
    ISSN 0016-3813
    ISSN 0016-3813
    DOI 10.24875/GMM.M21000583
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Herramientas de salud digital para superar la brecha de atención en epilepsia antes, durante y después de la pandemia de COVID-19.

    Santos-Peyret, A / Durón, R M / Sebastián-Díaz, M A / Crail-Meléndez, D / Goméz-Ventura, S / Briceño-González, E / Rito, Y / Martínez-Juárez, I E

    Revista de neurologia

    2020  Volume 70, Issue 9, Page(s) 323–328

    Abstract: Introduction: Epilepsy is a common chronic neurological disorder that affects around 50 million worldwide and there is an abundance of literature on the health care gap for this sector of the population. This gap will increase with the current pandemic ... ...

    Title translation E-health tools to overcome the gap in epilepsy care before, during and after COVID-19 pandemics.
    Abstract Introduction: Epilepsy is a common chronic neurological disorder that affects around 50 million worldwide and there is an abundance of literature on the health care gap for this sector of the population. This gap will increase with the current pandemic due to COVID-19.
    Aim: To evaluate the current availability of digital health tools for the care of people with epilepsy according to the world medical literature and their use during said pandemic.
    Development: We reviewed the publications in scientific journals in the last decade that had as their main topic the use of digital health tools or telemedicine focused on the care of patients with epilepsy, including 4 months after the national quarantines due to the appearance of the virus SARS-CoV-2. Seventeen publications were found on the use of telemedicine focused on epilepsy. The most widely used tools internationally are online platforms, followed by mobile applications, videoconferences, epileptic seizure capture systems, checklists, algorithms for understanding medical data, phone calls, tele-encephalography and text messages. None was published during the COVID-19 current pandemic.
    Conclusions: Although there is little literature on the use of digital health tools focused on epilepsy, there are several that can be used to fight the attention gap, especially in this global pandemic by COVID-19 that forces quarantines of people and communities for long periods. It is necessary to remove barriers and facilitate patient access to these new information technologies.
    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections/complications ; Coronavirus Infections/epidemiology ; Delivery of Health Care/trends ; Epilepsy/therapy ; Humans ; Mobile Applications ; Pandemics ; Patient Care/methods ; Patient Care/trends ; Pneumonia, Viral/complications ; Pneumonia, Viral/epidemiology ; Quarantine ; SARS-CoV-2 ; Telemedicine
    Keywords covid19
    Language Spanish
    Publishing date 2020-04-23
    Publishing country Spain
    Document type Journal Article ; Review
    ZDB-ID 1468278-3
    ISSN 1576-6578 ; 0210-0010
    ISSN (online) 1576-6578
    ISSN 0210-0010
    DOI 10.33588/rn.7009.2020173
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 5003: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  3. Article ; Online: Increased non-attendance at epilepsy clinic in patients with neuropsychiatric comorbidities: A prospective study.

    Zertuche-Ortuño, Lizeth / Oropeza-Bustos, Nayeli / Crail-Meléndez, Daniel / Bribiesca-Contreras, Elisa / Sebastián-Díaz, Mario A / Martínez-Bustos, Verónica / Santos-Peyret, Andrea / Martínez-Medina, Salvador / Ochoa, Adriana / Jara-Prado, Aurelio / Martínez-Juárez, Iris E

    Epilepsy & behavior : E&B

    2021  Volume 122, Page(s) 108202

    Abstract: Background: In patients with epilepsy, regular follow-up is vital for adequate seizure control, antiseizure drugs' (ASDs) side effects, psychiatric comorbidities, and planning for epilepsy surgery. Non-attendance creates barriers to adequate patient ... ...

    Abstract Background: In patients with epilepsy, regular follow-up is vital for adequate seizure control, antiseizure drugs' (ASDs) side effects, psychiatric comorbidities, and planning for epilepsy surgery. Non-attendance creates barriers to adequate patient care, inefficient allocation of resources, loss of income, and unnecessary emergency department visits due to lack of seizure control. This study aimed to determine the causes and sociodemographic characteristics of the non-attendant population at the Epilepsy Clinic.
    Methods: A prospective and observational study was carried out on patients treated at the Epilepsy Clinic of the National Institute of Neurology and Neurosurgery (NINN) in Mexico from August 2015 to June 2016. A phone interview was made with all those patients who did not attend the epilepsy consultation. This call incorporated ad hoc questions to meet the objectives of this study.
    Results: During the study period, 1299 patients had an appointment at the epilepsy clinic, where 233 (17.9%) patients missed their consultation, 123 (52.8%) were male, mean age was 35.9 ± 14.42 years. The most frequent cause of non-attendance was forgetfulness of the appointment in 62 patients (26.6%). Two patients died; no patient was reported to have experienced SUDEP. Non-attendant patients showed statistically significant overall prevalence of psychiatric comorbidities (41.6%), particularly depression, anxiety, and interictal psychosis.
    Conclusion: Information on non-attendance at various specialist consultations is scarce, and to our knowledge, this is the first study to address non-attendance in patients with epilepsy in Latin America. Improving hospital protocols to reduce non-attendance can increase patient adherence to follow-up, ultimately improving the quality of care in the epilepsy clinic.
    MeSH term(s) Adult ; Ambulatory Care Facilities ; Appointments and Schedules ; Epilepsy/complications ; Epilepsy/epidemiology ; Epilepsy/therapy ; Humans ; Male ; Middle Aged ; Prospective Studies ; Seizures ; Young Adult
    Language English
    Publishing date 2021-07-26
    Publishing country United States
    Document type Journal Article ; Observational Study
    ZDB-ID 2010587-3
    ISSN 1525-5069 ; 1525-5050
    ISSN (online) 1525-5069
    ISSN 1525-5050
    DOI 10.1016/j.yebeh.2021.108202
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 5289: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
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  4. Article ; Online: [No title information]

    Iris E. Martínez-Juárez / Aurelio Jara-Prado / Adriana Ochoa-Morales / Nancy Castro-Veloz / Andrea Santos-Peyret / Jimena Armenta-Báez / Mario A. Sebastián-Díaz

    Gaceta Médica de México, Vol 157, Iss

    2021  Volume 4

    Abstract: Introducción: Se ha reportado de 1 a 71 % de prevalencia de anormalidades ...

    Abstract Introducción: Se ha reportado de 1 a 71 % de prevalencia de anormalidades en el electroencefalograma (EEG) de familiares asintomáticos de pacientes con epilepsia mioclónica juvenil (EMJ). Objetivo: Determinar la frecuencia de anormalidades en el EEG en familiares asintomáticos de pacientes con EMJ de acuerdo con el grado de parentesco. Métodos: Estudio prospectivo y analítico. Se incluyeron familiares de primer, segundo y tercer grado de pacientes con EMJ, quienes aceptaron participar y firmaron el consentimiento informado. El análisis fue descriptivo bivariado. Resultados: Se incluyeron 209 familiares asintomáticos, 115 (55 %) mujeres y 94 (45 %) hombres, con edad media de 35.9 ± 16.9 (rango entre seis y 73 años); 44 familiares (21.1 %) tuvieron EEG anormal. Los familiares de primer grado (12 %) cursaron con mayor frecuencia con anormalidades en comparación con los de segundo y tercer grado (p = 0.007). Conclusiones: Se observaron anormalidades en el EEG de una tercera parte de los familiares asintomáticos. Es importante resaltar que existieron más alteraciones entre los familiares de primer grado. En un futuro, estos hallazgos permitirán estimar el riesgo de desarrollar la enfermedad clínicamente y brindar consejo genético.
    Keywords Electroencefalograma. Epilepsia mioclónica juvenil. Familiares asintomáticos ; Public aspects of medicine ; RA1-1270 ; Internal medicine ; RC31-1245
    Language English
    Publishing date 2021-10-01T00:00:00Z
    Publisher Permanyer
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article: Continuous Visual Focal Status Epilepticus as the Primary Presentation of NMDA-R and GAD65-R Autoimmune Epilepsy.

    Paredes-Aragón, Elma M / Valdéz-Ruvalcaba, Héctor E / Santos-Peyret, Andrea / Cisneros-Otero, Marcela / Medina-Rioja, Raúl / Orozco-Suárez, Sandra / Hernandez, Miriam M / Breda-Yepes, Michele D L / Rivas-Alonso, Verónica / Flores-Rivera, José J / Martínez-Juárez, Iris E

    Frontiers in neurology

    2020  Volume 11, Page(s) 598974

    Abstract: Epilepsia partialis continua ( ... ...

    Abstract Epilepsia partialis continua (EPC
    Language English
    Publishing date 2020-11-26
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2564214-5
    ISSN 1664-2295
    ISSN 1664-2295
    DOI 10.3389/fneur.2020.598974
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  6. Article: Herramientas de salud digital para superar la brecha de atención en epilepsia antes, durante y después de la pandemia de COVID-19./ [E-health tools to overcome the gap in epilepsy care before, during and after COVID-19 pandemics]

    Santos-Peyret, A / Durón, R M / Sebastián-Díaz, M A / Crail-Meléndez, D / Goméz-Ventura, S / Briceño-González, E / Rito, Y / Martínez-Juárez, I E

    Rev Neurol

    Abstract: INTRODUCTION: Epilepsy is a common chronic neurological disorder that affects around 50 million worldwide and there is an abundance of literature on the health care gap for this sector of the population. This gap will increase with the current pandemic ... ...

    Abstract INTRODUCTION: Epilepsy is a common chronic neurological disorder that affects around 50 million worldwide and there is an abundance of literature on the health care gap for this sector of the population. This gap will increase with the current pandemic due to COVID-19. AIM: To evaluate the current availability of digital health tools for the care of people with epilepsy according to the world medical literature and their use during said pandemic. DEVELOPMENT: We reviewed the publications in scientific journals in the last decade that had as their main topic the use of digital health tools or telemedicine focused on the care of patients with epilepsy, including 4 months after the national quarantines due to the appearance of the virus SARS-CoV-2. Seventeen publications were found on the use of telemedicine focused on epilepsy. The most widely used tools internationally are online platforms, followed by mobile applications, videoconferences, epileptic seizure capture systems, checklists, algorithms for understanding medical data, phone calls, tele-encephalography and text messages. None was published during the COVID-19 current pandemic. CONCLUSIONS: Although there is little literature on the use of digital health tools focused on epilepsy, there are several that can be used to fight the attention gap, especially in this global pandemic by COVID-19 that forces quarantines of people and communities for long periods. It is necessary to remove barriers and facilitate patient access to these new information technologies.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #116388
    Database COVID19

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  7. Article ; Online: Non-motor symptom burden is strongly correlated to motor complications in patients with Parkinson's disease.

    Santos-García, D / de Deus Fonticoba, T / Suárez Castro, E / Aneiros Díaz, A / McAfee, D / Catalán, M J / Alonso-Frech, F / Villanueva, C / Jesús, S / Mir, P / Aguilar, M / Pastor, P / García Caldentey, J / Esltelrich Peyret, E / Planellas, L L / Martí, M J / Caballol, N / Hernández Vara, J / Martí Andrés, G /
    Cabo, I / Ávila Rivera, M A / López Manzanares, L / Redondo, N / Martinez-Martin, P

    European journal of neurology

    2020  Volume 27, Issue 7, Page(s) 1210–1223

    Abstract: Background and purpose: The objective of this study was to analyze the relationship between motor complications and non-motor symptom (NMS) burden in a population of patients with Parkinson's disease (PD) and also in a subgroup of patients with early PD. ...

    Abstract Background and purpose: The objective of this study was to analyze the relationship between motor complications and non-motor symptom (NMS) burden in a population of patients with Parkinson's disease (PD) and also in a subgroup of patients with early PD.
    Methods: Patients with PD from the COPPADIS cohort were included in this cross-sectional study. NMS burden was defined according to the Non-Motor Symptoms Scale (NMSS) total score. Unified Parkinson's Disease Rating Scale (UPDRS) part IV was used to establish motor complication types and their severity. Patients with ≤5 years of symptoms from onset were included as patients with early PD.
    Results: Of 690 patients with PD (62.6 ± 8.9 years old, 60.1% males), 33.9% and 18.1% presented motor fluctuations and dyskinesia, respectively. The NMS total score was higher in patients with motor fluctuations (59.2 ± 43.1 vs. 38.3 ± 33.1; P < 0.0001) and dyskinesia (63.5 ± 40.7 vs. 41.4 ± 36.3; P < 0.0001). In a multiple linear regression model and after adjustment for age, sex, disease duration, Hoehn & Yahr stage, UPDRS-III score and levodopa equivalent daily dose, UPDRS-IV score was significantly related to a higher NMSS total score (β = 0.27; 95% confidence intervals, 2.81-5.61; P < 0.0001), as it was in a logistic regression model on dichotomous NMSS total score (≤40, mild or moderate vs. >40, severe or very severe) (odds ratio, 1.31; 95% confidence intervals, 1.17-1.47; P < 0.0001). In the subgroup of patients with early PD (n = 396; mean disease duration 2.7 ± 1.5 years), motor fluctuations were frequent (18.1%) and similar results were obtained.
    Conclusions: Motor complications were frequent and were associated with a greater NMS burden in patients with PD even during the first 5 years of disease duration.
    MeSH term(s) Aged ; Cross-Sectional Studies ; Female ; Humans ; Levodopa/therapeutic use ; Male ; Middle Aged ; Parkinson Disease/complications ; Parkinson Disease/epidemiology ; Severity of Illness Index
    Chemical Substances Levodopa (46627O600J)
    Language English
    Publishing date 2020-04-24
    Publishing country England
    Document type Journal Article
    ZDB-ID 1280785-0
    ISSN 1468-1331 ; 1351-5101 ; 1471-0552
    ISSN (online) 1468-1331
    ISSN 1351-5101 ; 1471-0552
    DOI 10.1111/ene.14221
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    Zs.MO 592: Show issues

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