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  1. Article ; Online: Antiferromagnetic Semiconductor BaMnO

    Li, Hongping / Guo, Baochang / Xu, Dongshuo / Wang, Zhangyan / Fan, Weiqiang / Tian, Yi

    Inorganic chemistry

    2024  Volume 63, Issue 15, Page(s) 6813–6821

    Abstract: The unique properties of direct bandgap semiconductors make it important to search for semiconductors exhibiting this phenomenon in perovskite materials. In this study, we employed first-principles calculations to investigate the crystal structures, ... ...

    Abstract The unique properties of direct bandgap semiconductors make it important to search for semiconductors exhibiting this phenomenon in perovskite materials. In this study, we employed first-principles calculations to investigate the crystal structures, magnetic configurations, and electronic properties of hexagonal perovskite BaMnO
    Language English
    Publishing date 2024-04-04
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1484438-2
    ISSN 1520-510X ; 0020-1669
    ISSN (online) 1520-510X
    ISSN 0020-1669
    DOI 10.1021/acs.inorgchem.4c00249
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: A Point Cloud Data-Driven Pallet Pose Estimation Method Using an Active Binocular Vision Sensor.

    Shao, Yiping / Fan, Zhengshuai / Zhu, Baochang / Lu, Jiansha / Lang, Yiding

    Sensors (Basel, Switzerland)

    2023  Volume 23, Issue 3

    Abstract: Pallet pose estimation is one of the key technologies for automated fork pickup of driverless industrial trucks. Due to the complex working environment and the enormous amount of data, the existing pose estimation approaches cannot meet the working ... ...

    Abstract Pallet pose estimation is one of the key technologies for automated fork pickup of driverless industrial trucks. Due to the complex working environment and the enormous amount of data, the existing pose estimation approaches cannot meet the working requirements of intelligent logistics equipment in terms of high accuracy and real time. A point cloud data-driven pallet pose estimation method using an active binocular vision sensor is proposed, which consists of point cloud preprocessing, Adaptive Gaussian Weight-based Fast Point Feature Histogram extraction and point cloud registration. The proposed method overcomes the shortcomings of traditional pose estimation methods, such as poor robustness, time consumption and low accuracy, and realizes the efficient and accurate estimation of pallet pose for driverless industrial trucks. Compared with traditional Fast Point Feature Histogram and Signature of Histogram of Orientation, the experimental results show that the proposed approach is superior to the above two methods, improving the accuracy by over 35% and reducing the feature extraction time by over 30%, thereby verifying the effectiveness and superiority of the proposed method.
    Language English
    Publishing date 2023-01-20
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2052857-7
    ISSN 1424-8220 ; 1424-8220
    ISSN (online) 1424-8220
    ISSN 1424-8220
    DOI 10.3390/s23031217
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Scientific creativity and innovation ability and its determinants among medical postgraduate students in Fujian province of China: a cross sectional study.

    Liu, Fengqiong / Qu, Shuming / Fan, Yi / Chen, Fa / He, Baochang

    BMC medical education

    2023  Volume 23, Issue 1, Page(s) 444

    Abstract: Background: Graduate education is the main approach to training high-level innovative elites. With the expansion of the scale of graduate education in China, it has gradually emerged that the lack of innovation ability of graduate students is recognized ...

    Abstract Background: Graduate education is the main approach to training high-level innovative elites. With the expansion of the scale of graduate education in China, it has gradually emerged that the lack of innovation ability of graduate students is recognized as the primary problem in graduate education. How to comprehensively improve the quality of postgraduate teaching has become the core task of educational reform and development. However, data about the current cultivation and development of the innovative ability of graduate students in China is limited.
    Methods: A questionnaire survey was conducted among medical postgraduate students. Descriptive statistics and multiple regression analysis methods were used to analyze the data to describe the current innovation ability in advanced medical education and potential influence factors.
    Results: A total of 1241 medical students were surveyed, according to the results of questionnaire data analysis. The proportion of subjects who participated in the College Student's Entrepreneurship and Innovation program or any other scientific research programs are fairly high which are 46.82% and 29.20% respectively. Most of the participants are observed with high levels of self-motivation and active learning and have good performance in creative thinking. However, only a small number of participants (16.6%) reported academic achievements such as publications. Most of the students are satisfied with the current scientific research environment and think that the current postgraduate training system is qualified for the cultivation of innovation ability, and expects the inclusion of course specialized in systemic medicine and medical informatics in the curricula. Multiple logistic regression results showed that among the factors studied, gender, medical specialties, and types of master's degrees are associated with cognition & skills, academic performance, and creativity.
    Conclusions: It will be important to incorporate more techniques for creating and improving creativity in the curricula of the current postgraduate education, especially for courses such as systemic medicine and informatics. Guidance in earlier school life can stimulate creativity and an early introduction to scientific research work will facilitate innovative thinking and behavior. Scientific research programs such as the National Innovation and Entrepreneurship Training for the universities of PRC have been widely implemented in the undergraduate education system throughout the country. However, the training effectiveness of the current scientific research programs is worth improving.
    MeSH term(s) Humans ; Creativity ; Cross-Sectional Studies ; Students, Medical ; Curriculum ; China
    Language English
    Publishing date 2023-06-16
    Publishing country England
    Document type Journal Article
    ZDB-ID 2044473-4
    ISSN 1472-6920 ; 1472-6920
    ISSN (online) 1472-6920
    ISSN 1472-6920
    DOI 10.1186/s12909-023-04408-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Author Correction: Selective modulation of the androgen receptor AF2 domain rescues degeneration in spinal bulbar muscular atrophy.

    Badders, Nisha M / Korff, Ane / Miranda, Helen C / Vuppala, Pradeep K / Smith, Rebecca B / Winborn, Brett J / Quemin, Emmanuelle R / Sopher, Bryce L / Dearman, Jennifer / Messing, James / Kim, Nam Chul / Moore, Jennifer / Freibaum, Brian D / Kanagaraj, Anderson P / Fan, Baochang / Tillman, Heather / Chen, Ping-Chung / Wang, Yingzhe / Freeman, Burgess B /
    Li, Yimei / Kim, Hong Joo / La Spada, Albert R / Taylor, J Paul

    Nature medicine

    2024  Volume 30, Issue 3, Page(s) 909–910

    Language English
    Publishing date 2024-03-25
    Publishing country United States
    Document type Published Erratum
    ZDB-ID 1220066-9
    ISSN 1546-170X ; 1078-8956
    ISSN (online) 1546-170X
    ISSN 1078-8956
    DOI 10.1038/s41591-023-02778-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: A Novel Pallet Detection Method for Automated Guided Vehicles Based on Point Cloud Data.

    Shao, Yiping / Fan, Zhengshuai / Zhu, Baochang / Zhou, Minlong / Chen, Zhihui / Lu, Jiansha

    Sensors (Basel, Switzerland)

    2022  Volume 22, Issue 20

    Abstract: Automated guided vehicles are widely used in warehousing environments for automated pallet handling, which is one of the fundamental parts to construct intelligent logistics systems. Pallet detection is a critical technology for automated guided vehicles, ...

    Abstract Automated guided vehicles are widely used in warehousing environments for automated pallet handling, which is one of the fundamental parts to construct intelligent logistics systems. Pallet detection is a critical technology for automated guided vehicles, which directly affects production efficiency. A novel pallet detection method for automated guided vehicles based on point cloud data is proposed, which consists of five modules including point cloud preprocessing, key point extraction, feature description, surface matching and point cloud registration. The proposed method combines the color with the geometric features of the pallet point cloud and constructs a new Adaptive Color Fast Point Feature Histogram (ACFPFH) feature descriptor by selecting the optimal neighborhood adaptively. In addition, a new surface matching method called the Bidirectional Nearest Neighbor Distance Ratio-Approximate Congruent Triangle Neighborhood (BNNDR-ACTN) is proposed. The proposed method overcomes the problems of current methods such as low efficiency, poor robustness, random parameter selection, and being time-consuming. To verify the performance, the proposed method is compared with the traditional and modified Iterative Closest Point (ICP) methods in two real-world cases. The results show that the Root Mean Square Error (RMSE) is reduced to 0.009 and the running time is reduced to 0.989 s, which demonstrates that the proposed method has faster registration speed while maintaining higher registration accuracy.
    Language English
    Publishing date 2022-10-20
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2052857-7
    ISSN 1424-8220 ; 1424-8220
    ISSN (online) 1424-8220
    ISSN 1424-8220
    DOI 10.3390/s22208019
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Clinical value and molecular mechanism of AQGPs in different tumors.

    Wang, Rui / Wang, Xuejian / Zhao, Jun / Jin, Jiacheng / Fan, Weiwei / Zhu, Xinqing / Chen, Qiwei / Zhang, Baochang / Lan, Lan / Qu, Kexin / Zhu, Liang / Wang, Jianbo

    Medical oncology (Northwood, London, England)

    2022  Volume 39, Issue 11, Page(s) 174

    Abstract: Aquaglyceroporins (AQGPs), including AQP3, AQP7, AQP9, and AQP10, are transmembrane channels that allow small solutes across biological membranes, such as water, glycerol, ... ...

    Abstract Aquaglyceroporins (AQGPs), including AQP3, AQP7, AQP9, and AQP10, are transmembrane channels that allow small solutes across biological membranes, such as water, glycerol, H
    MeSH term(s) Aquaglyceroporins/metabolism ; Glycerol/metabolism ; Humans ; Hydrogen Peroxide ; Neoplasms/genetics
    Chemical Substances Aquaglyceroporins ; Hydrogen Peroxide (BBX060AN9V) ; Glycerol (PDC6A3C0OX)
    Language English
    Publishing date 2022-08-16
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1201189-7
    ISSN 1559-131X ; 0736-0118 ; 1357-0560
    ISSN (online) 1559-131X
    ISSN 0736-0118 ; 1357-0560
    DOI 10.1007/s12032-022-01766-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: PPARγ induces NEDD4 gene expression to promote autophagy and insulin action

    Liu, Jia / Yao, Qinyu / Xiao, Lei / Ma, Wen / Li, Fan / Lai, Baochang / Wang, Nanping

    FEBS journal. 2020 Feb., v. 287, no. 3

    2020  

    Abstract: The E3 ubiquitin ligase neural precursor cell‐expressed developmentally down‐regulated protein 4 (NEDD4) plays a crucial role in governing a number of signaling pathways, including insulin and autophagy signaling. However, the molecular mechanism by ... ...

    Abstract The E3 ubiquitin ligase neural precursor cell‐expressed developmentally down‐regulated protein 4 (NEDD4) plays a crucial role in governing a number of signaling pathways, including insulin and autophagy signaling. However, the molecular mechanism by which NEDD4 gene is transcriptionally regulated has not been fully elucidated. Here, we reported that NEDD4 mRNA and protein levels were increased by peroxisome proliferator‐activated receptor‐γ (PPARγ) in HepG2 hepatocytes. PPARγ antagonist GW9662 abolished thiazolidinedione (TZD)‐induced NEDD4 expression. ChIP and luciferase reporter assays showed that PPARγ directly bound to the potential PPAR‐responsive elements (PPREs) within the promoter region of the human NEDD4 gene. In addition, TZDs increased Akt phosphorylation and glucose uptake, which were abrogated through NEDD4 depletion. Furthermore, we showed that NEDD4‐mediated autophagy induction and Akt phosphorylation were suppressed by oleic acid and high glucose treatment, activation of PPARγ successfully prevented this suppression. In conclusion, these results suggest that PPARγ plays a novel role in linking glucose metabolism and protein homeostasis through NEDD4‐mediated effects on the autophagy machinery.
    Keywords antagonists ; autophagy ; gene expression ; genes ; glucose ; hepatocytes ; homeostasis ; humans ; insulin ; luciferase ; metabolism ; oleic acid ; phosphorylation ; promoter regions ; transcription (genetics) ; ubiquitin-protein ligase
    Language English
    Dates of publication 2020-02
    Size p. 529-545.
    Publishing place John Wiley & Sons, Ltd
    Document type Article
    Note NAL-AP-2-clean ; JOURNAL ARTICLE
    ZDB-ID 2173655-8
    ISSN 1742-4658 ; 1742-464X
    ISSN (online) 1742-4658
    ISSN 1742-464X
    DOI 10.1111/febs.15042
    Database NAL-Catalogue (AGRICOLA)

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  8. Article ; Online: Relationship Between Dietary Fiber and Vitamin C Intake and Oral Cancer.

    Wang, Jing / Fan, Yi / Qian, Jiawen / Wang, Sijie / Li, Yanni / Xu, Mingming / Chen, Fa / Qiu, Yu / Lin, Lisong / He, Baochang / Liu, Fengqiong

    Frontiers in public health

    2022  Volume 10, Page(s) 880506

    Abstract: Background: Dietary fiber and vitamin C has been reported to play a possible role in tumorigenesis. However, few studies have estimated their association with oral cancer risk. In this project, we investigated the relationship between dietary fiber and ... ...

    Abstract Background: Dietary fiber and vitamin C has been reported to play a possible role in tumorigenesis. However, few studies have estimated their association with oral cancer risk. In this project, we investigated the relationship between dietary fiber and vitamin C and oral cancer risk in adults in Southern China.
    Methods: 382 patients newly diagnosed with oral cancer were matched to 382 hospital derived controls by frequency matching in age and sex. Pre-diagnostic consumption of dietary fiber and vitamin C intake were measured through food frequency questionnaire. Association between nutrients intake and oral cancer risk were evaluated by logistic regression. OR value and 95% confidence interval was calculated.
    Results: Intake of dietary fiber and vitamin C was significantly lower in oral cancer patients (8.15 g/day) than in control participants (8.88 g/day). Increased dietary fiber or vitamin C intake was linked to a decreased incidence of OC after adjustment of age, marital status, residence, BMI, occupation, education, tobacco smoking, alcohol consumption and family history of cancer
    Conclusions: Dietary intake of fiber and vitamin C were lower in oral cancer patients than in control participants. Dietary fiber and vitamin C were inversely related to risk of oral cancer risk.
    MeSH term(s) Adult ; Ascorbic Acid ; Case-Control Studies ; Dietary Fiber ; Humans ; Mouth Neoplasms/epidemiology ; Risk Factors
    Chemical Substances Dietary Fiber ; Ascorbic Acid (PQ6CK8PD0R)
    Language English
    Publishing date 2022-05-12
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2711781-9
    ISSN 2296-2565 ; 2296-2565
    ISSN (online) 2296-2565
    ISSN 2296-2565
    DOI 10.3389/fpubh.2022.880506
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Association Between Dietary Fatty Acid Pattern and Risk of Oral Cancer.

    Fan, Yi / Qiu, Yu / Wang, Jing / Chen, Qing / Wang, Sijie / Wang, Yaping / Li, Yanni / Weng, Yanfeng / Qian, Jiawen / Chen, Fa / Shi, Bin / Pan, Lizhen / Lin, Lisong / He, Baochang / Liu, Fengqiong

    Frontiers in nutrition

    2022  Volume 9, Page(s) 864098

    Abstract: Objective: To investigate the association between dietary fatty acid (FA) patterns and the risk of oral cancer.: Method: A case-control study which included 446 patients with oral cancer and 448 controls subjects was conducted in Southeast China. A ... ...

    Abstract Objective: To investigate the association between dietary fatty acid (FA) patterns and the risk of oral cancer.
    Method: A case-control study which included 446 patients with oral cancer and 448 controls subjects was conducted in Southeast China. A structured food frequency questionnaire was used to assess the dietary FA consumption before cancer diagnosis. FA patterns were identified using the principal component analysis, and the relationship between the dietary FA patterns and oral cancer was analyzed by logistic regression.
    Results: General differences in FA intake were observed between the patient and control groups. The intakes of saturated FAs (SFAs) C14:0, C16:0, C18:0, and monounsaturated FA C18:1 were higher in the patient group than the control group (
    Conclusions: General differences in dietary FA intake were observed between patients with oral cancer and controls. A positive association between the "SFA" pattern and risk of oral cancer was observed after adjusting for potential confounders.
    Language English
    Publishing date 2022-05-16
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2776676-7
    ISSN 2296-861X
    ISSN 2296-861X
    DOI 10.3389/fnut.2022.864098
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Development and Clinical Validation of a Novel 5 Gene Signature Based on Fatty Acid Metabolism-Related Genes in Oral Squamous Cell Carcinoma.

    Fan, Yi / Wang, Jing / Wang, Yaping / Li, Yanni / Wang, Sijie / Weng, Yanfeng / Yang, Qiujiao / Chen, Chen / Lin, Lisong / Qiu, Yu / Chen, Fa / He, Baochang / Liu, Fengqiong

    Oxidative medicine and cellular longevity

    2022  Volume 2022, Page(s) 3285393

    Abstract: Background/aim: Lipid metabolism disorders play a crucial role in tumor development and progression. The aim of the study focused on constructing a novel prognostic model of oral squamous cell carcinoma (OSCC) patients using fatty acid metabolism- ... ...

    Abstract Background/aim: Lipid metabolism disorders play a crucial role in tumor development and progression. The aim of the study focused on constructing a novel prognostic model of oral squamous cell carcinoma (OSCC) patients using fatty acid metabolism-related genes.
    Methods: Microarray test and data from The Cancer Genome Atlas (TCGA) were used to identify differentially expressed genes related to fatty acid metabolism. The quantitative real-time polymerase chain reaction (qRT-PCR) was then used to validate the expression of targeted fatty acid metabolism genes. A risk predictive scoring model of fatty acid metabolism-related genes was generated using a multivariate Cox model. The efficacy of this model was assessed by time-dependent receiver operating characteristic curve (ROC).
    Results: 14 fatty acid metabolism-related genes were identified by microarray test and TCGA database analysis and then confirmed by PCR. Finally, a 5 gene signature (ACACB, FABP3, PDK4, PPARG, and PLIN5) was constructed and a RiskScore was calculated for each patient. Compared to the high RiskScore group, the low RiskScore group had better overall survival (OS) (
    Conclusion: We developed a predictive score model using 5 fatty acid metabolism-related genes, which could be a potential prognostic indicator in OSCC.
    MeSH term(s) Humans ; Mouth Neoplasms/genetics ; Carcinoma, Squamous Cell/genetics ; Squamous Cell Carcinoma of Head and Neck ; Head and Neck Neoplasms ; Fatty Acids
    Chemical Substances Fatty Acids
    Language English
    Publishing date 2022-11-28
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2455981-7
    ISSN 1942-0994 ; 1942-0994
    ISSN (online) 1942-0994
    ISSN 1942-0994
    DOI 10.1155/2022/3285393
    Database MEDical Literature Analysis and Retrieval System OnLINE

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