LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 30

Search options

  1. Article ; Online: Clinic Use at the Departments of Defense and Veterans Affairs Following Combat Related Amputations.

    Melcer, Ted / Walker, Jay / Bhatnagar, Vibha / Richard, Erin

    Military medicine

    2019  Volume 185, Issue 1-2, Page(s) e244–e253

    Abstract: Introduction: Little population-based research has described the transition from Department of Defense (DoD) to Department of Veterans Affairs (VA) healthcare following combat related amputations. The objectives were to describe (1) to what extent ... ...

    Abstract Introduction: Little population-based research has described the transition from Department of Defense (DoD) to Department of Veterans Affairs (VA) healthcare following combat related amputations. The objectives were to describe (1) to what extent patients used either DoD only facilities, both DoD and VA facilities, or VA only facilities during the first 5 years postinjury, (2) which specific clinics were used and (3) clinic use among patients with different levels of amputation (upper versus lower), and among patients with early or late amputation.
    Materials and methods: This was a retrospective analysis of health data extracted from the expeditionary medical encounter database (EMED) and national DoD and VA databases. Patients were 649 US service members who sustained a single major limb amputation following injuries in the Iraq and Afghanistan conflicts, 2001-2008. We compared yearly DoD and VA clinic use by patient groups with different levels of amputation (upper limb: above versus below elbow or lower limb: above versus below knee), different timing of amputation (early: within 90 days postinjury versus late: more than 90 days postinjury), military component (Active Duty versus National Guard/Reserve) and race (White versus Black). For all groups, we calculated the percentage of patients using: (1) DoD only, (2) both DoD and VA or 3) VA only clinics during each of postinjury years 1 through 5. We also calculated the percentage of patients who used specific clinics (e.g., social work, prosthetics, mental health) during each postinjury year.
    Results: During postinjury year 1, over 98% of patients used DoD only or both DoD and VA clinics. Most individuals (70% to 78%) used both DoD and VA clinics during postinjury year 1. Use of VA only clinics increased gradually between postinjury year 2 (15% to 30% of patient groups) and year 5 (75% to 88%). This gradual transition to use of VA only clinics was seen consistently across patient groups with different anatomical levels or timing of amputation, military component or race. Patients with lower levels of amputation (versus higher levels) and individuals with early amputations (versus late) transitioned earlier to VA only care. Overall, clinic use was high as 91% to 100% of all patient groups used one or more clinics (DoD or VA) during each of the first 5 years. For specific clinics, most patients used DoD facilities related to rehabilitation (physical therapy, prosthetics) or transitional care (social work) particularly during postinjury year 1. Use of most VA clinics studied (social work, primary care, prosthetics, mental health) showed a modest increase primarily after postinjury year 1 and remained stable through postinjury year 5. The results indicated apparent underuse of psychiatric/mental health and prosthetics between postinjury year 1 and 2.
    Conclusions: The present study indicated a gradual transition from DoD to VA only healthcare which extended across 5 years following combat related amputations. Patients with lower levels of amputation or early amputation generally transitioned earlier to VA only healthcare. These results can inform medical planning to support a timely and clinically effective transition from DoD to VA healthcare.
    MeSH term(s) Afghanistan ; Amputation ; Humans ; Iraq ; Retrospective Studies ; United States/epidemiology ; United States Department of Veterans Affairs ; Veterans
    Language English
    Publishing date 2019-06-25
    Publishing country England
    Document type Journal Article ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 391061-1
    ISSN 1930-613X ; 0026-4075
    ISSN (online) 1930-613X
    ISSN 0026-4075
    DOI 10.1093/milmed/usz149
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  2. Article ; Online: Is Prehospital Ketamine Associated With a Change in the Prognosis of PTSD?

    Melcer, Ted / Walker, G Jay / Dye, Judy L / Walrath, Benjamin / MacGregor, Andrew J / Perez, Katheryne / Galarneau, Michael R

    Military medicine

    2022  

    Abstract: Introduction: Ketamine is an alternative to opioids for prehospital analgesia following serious combat injury. Limited research has examined prehospital ketamine use, associated injuries including traumatic brain injury (TBI) and PTSD outcomes following ...

    Abstract Introduction: Ketamine is an alternative to opioids for prehospital analgesia following serious combat injury. Limited research has examined prehospital ketamine use, associated injuries including traumatic brain injury (TBI) and PTSD outcomes following serious combat injury.
    Materials and methods: We randomly selected 398 U.S. service members from the Expeditionary Medical Encounter Database who sustained serious combat injuries in Iraq and Afghanistan, 2010-2013. Of these 398 patients, 213 individuals had charted prehospital medications. Clinicians reviewed casualty records to identify injuries and all medications administered. Outcomes were PTSD diagnoses during the first year and during the first 2 years postinjury extracted from military health databases. We compared PTSD outcomes for patients treated with either (a) prehospital ketamine (with or without opioids) or (b) prehospital opioids (without ketamine).
    Results: Fewer patients received prehospital ketamine (26%, 56 of 213) than only prehospital opioids (69%, 146 of 213) (5%, 11 of 213 received neither ketamine nor opioids). The ketamine group averaged significantly more moderate-to-serious injuries, particularly lower limb amputations and open wounds, compared with the opioid group (Ps < .05). Multivariable regressions showed a significant interaction between prehospital ketamine (versus opioids) and TBI on first-year PTSD (P = .027). In subsequent comparisons, the prehospital ketamine group had significantly lower odds of first-year PTSD (OR = 0.08, 95% CI [0.01, 0.71], P = .023) versus prehospital opioids only among patients who did not sustain TBI. We also report results from separate analyses of PTSD outcomes among patients treated with different prehospital opioids only (without ketamine), either morphine or fentanyl.
    Conclusions: The present results showed that patients treated with prehospital ketamine had significantly lower odds of PTSD during the first year postinjury only among patients who did not sustain TBI. These findings can inform combat casualty care guidelines for use of prehospital ketamine and opioid analgesics following serious combat injury.
    Language English
    Publishing date 2022-02-01
    Publishing country England
    Document type Journal Article
    ZDB-ID 391061-1
    ISSN 1930-613X ; 0026-4075
    ISSN (online) 1930-613X
    ISSN 0026-4075
    DOI 10.1093/milmed/usac014
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  3. Article ; Online: Retrospective study of cardiovascular disease risk factors among a cohort of combat veterans with lower limb amputation.

    Bhatnagar, Vibha / Richard, Erin / Melcer, Ted / Walker, Jay / Galarneau, Michael

    Vascular health and risk management

    2019  Volume 15, Page(s) 409–418

    Abstract: Introduction: Previous studies have shown that veterans with lower limb amputation have a higher risk for cardiovascular disease (CVD) compared with population-based controls. American veterans who have served in Iraq and Afghanistan with lower limb ... ...

    Abstract Introduction: Previous studies have shown that veterans with lower limb amputation have a higher risk for cardiovascular disease (CVD) compared with population-based controls. American veterans who have served in Iraq and Afghanistan with lower limb amputation may be at a similarly higher risk.
    Patients and methods: The Navel Health Research Center (NHRC) maintains the Expeditionary Medical Encounter Database (EMED) of military personnel who have sustained combat limb amputation or serious limb injury during the conflicts in Iraq and Afghanistan. Department of Veterans Affairs data from 2003 to April 2015 was used to analyze CVD risk factors in this cohort. Veterans with either unilateral (n=442) or bilateral (n
    Results: Compared with the limb injury group, those with unilateral lower limb amputation had significantly lower HDL (
    Conclusions: Results suggest that veterans with lower limb amputation have a higher risk for metabolic syndrome. Primary care interventions to manage weight, blood pressure, and lipid levels are fundamental in order to reduce cardiac risk in this relatively young cohort.
    MeSH term(s) Adult ; Afghan Campaign 2001- ; Amputation/adverse effects ; Biomarkers/blood ; Cardiovascular Diseases/blood ; Cardiovascular Diseases/diagnosis ; Cardiovascular Diseases/epidemiology ; Cardiovascular Diseases/physiopathology ; Databases, Factual ; Female ; Hemodynamics ; Humans ; Iraq War, 2003-2011 ; Lipids/blood ; Lower Extremity/blood supply ; Male ; Metabolic Syndrome/blood ; Metabolic Syndrome/diagnosis ; Metabolic Syndrome/epidemiology ; Metabolic Syndrome/physiopathology ; Middle Aged ; Prevalence ; Prognosis ; Retrospective Studies ; Risk Assessment ; Risk Factors ; United States/epidemiology ; United States Department of Veterans Affairs ; Vascular System Injuries/diagnosis ; Vascular System Injuries/epidemiology ; Vascular System Injuries/physiopathology ; Vascular System Injuries/surgery ; Veterans Health
    Chemical Substances Biomarkers ; Lipids
    Language English
    Publishing date 2019-09-19
    Publishing country New Zealand
    Document type Journal Article
    ZDB-ID 2186568-1
    ISSN 1178-2048 ; 1176-6344
    ISSN (online) 1178-2048
    ISSN 1176-6344
    DOI 10.2147/VHRM.S212729
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  4. Article ; Online: Outpatient Pharmacy Prescriptions During the First Year Following Serious Combat Injury: A Retrospective Analysis.

    Melcer, Ted / Walker, Jay / Sazon, Jocelyn / Domasing, Robby / Perez, Katheryne / Bhatnagar, Vibha / Galarneau, Michael

    Military medicine

    2020  Volume 185, Issue 7-8, Page(s) e1091–e1100

    Abstract: Introduction: Limited research has analyzed the full range of outpatient medication prescription activity following serious combat injury. The objectives of this study were to describe (1) outpatient medication prescriptions and refills during the first ...

    Abstract Introduction: Limited research has analyzed the full range of outpatient medication prescription activity following serious combat injury. The objectives of this study were to describe (1) outpatient medication prescriptions and refills during the first 12 months after serious combat injury, (2) longitudinal changes in medication prescriptions during the first-year postinjury, and (3) patient characteristics associated with outpatient prescriptions.
    Materials and methods: This was a retrospective analysis of existing health and pharmacy data for a random sample of U.S. service members who sustained serious combat injuries in the Iraq and Afghanistan conflicts, 2010-2013 (n = 381). Serious injury was defined by an Injury Severity Score (ISS) of 9 or greater. These patients typically participate in military rehabilitation programs (eg, amputation care) where prescription medications are essential. Data sources were the Expeditionary Medical Encounter Database for injury-specific data, the Pharmacy Data Transaction Service for outpatient medication prescriptions and refills, and the Military Health System Data Repository for diagnostic codes of pain and psychological disorders. Military trauma nurses reviewed casualty records to identify types of injuries. Using the American Hospital Formulary Service Pharmacologic-Therapeutic Classification system, clinicians identified 13 categories of prescription medications (eg, opioid, psychotherapeutic, immunologic) for analysis. Multivariable negative binomial and logistic regression analyses evaluated significant associations between independent variables (eg, blast injury, traumatic brain injury [TBI], ISS, limb amputation, diagnoses of chronic pain, or psychological disorders) and prescription measures (ie, number or category of medication prescriptions). We also describe longitudinal changes in prescription activity postinjury across consecutive quarterly intervals (91 days) during the first-year postinjury.
    Results: During the first-year postinjury, patients averaged 61 outpatient prescriptions, including all initial prescriptions and refills. They averaged eight different categories of medications, primarily opioid, immunologic, gastrointestinal/genitourinary, central nervous system (CNS), nonopioid analgesic, and psychotherapeutic medications (representing 82% of prescriptions) during the first year. Prescription activity generally declined across quarters. There was still substantial prescription activity during the fourth quarter, as 79% of patients had at least one prescription. From 39 to 49% of patients had fourth-quarter prescriptions for opioid, CNS, or psychotherapeutic medications. Longitudinally, we found that 24-34% of patients had an opioid, CNS, or psychotherapeutic prescription during each of the final three quarters. In multivariable analysis, ISS, limb amputation (particularly bilateral amputation), and diagnoses of chronic pain and post-traumatic stress disorder (PTSD) were associated with significantly higher counts of individual and multiple medication prescriptions. TBI was associated with significantly lower numbers of prescriptions for certain medications.
    Conclusions: This is one of the first studies to provide a systematic analysis of outpatient medication prescriptions following serious combat injury. The results indicate substantial prescription activity from multiple medication categories throughout the first-year postinjury. Diagnoses of chronic pain, PTSD, and limb amputation and ISS were associated with significantly higher counts of prescriptions overall and more prescription medication categories. This study provides initial evidence to better understand medication prescription activity following serious combat injury. The results inform future research on medication prescription practices and planning for rehabilitation.
    MeSH term(s) Afghanistan ; Humans ; Iraq ; Military Personnel ; Outpatients ; Pharmacy ; Retrospective Studies ; United States
    Language English
    Publishing date 2020-03-15
    Publishing country England
    Document type Journal Article ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 391061-1
    ISSN 1930-613X ; 0026-4075
    ISSN (online) 1930-613X
    ISSN 0026-4075
    DOI 10.1093/milmed/usaa038
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  5. Article ; Online: Correction: A Comparison of Four-Year Health Outcomes following Combat Amputation and Limb Salvage.

    Melcer, Ted / Walker, Jay / Bhatnagar, Vibha / Richard, Erin / Sechriest Ii, V Franklin / Galarneau, Michael

    PloS one

    2017  Volume 12, Issue 2, Page(s) e0173214

    Abstract: This corrects the article DOI: 10.1371/journal.pone.0170569.]. ...

    Abstract [This corrects the article DOI: 10.1371/journal.pone.0170569.].
    Language English
    Publishing date 2017-02-27
    Publishing country United States
    Document type Published Erratum
    ISSN 1932-6203
    ISSN (online) 1932-6203
    DOI 10.1371/journal.pone.0173214
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  6. Article ; Online: A Comparison of Four-Year Health Outcomes following Combat Amputation and Limb Salvage.

    Melcer, Ted / Walker, Jay / Bhatnagar, Vibha / Richard, Erin / Sechriest, V Franklin / Galarneau, Michael

    PloS one

    2017  Volume 12, Issue 1, Page(s) e0170569

    Abstract: Little research has described the long-term health outcomes of patients who had combat-related amputations or leg-threatening injuries. We conducted retrospective analysis of Department of Defense and Department of Veterans Affairs health data for lower ... ...

    Abstract Little research has described the long-term health outcomes of patients who had combat-related amputations or leg-threatening injuries. We conducted retrospective analysis of Department of Defense and Department of Veterans Affairs health data for lower extremity combat-injured patients with (1) unilateral amputation within 90 days postinjury (early amputation, n = 440), (2) unilateral amputation more than 90 days postinjury (late amputation, n = 78), or (3) leg-threatening injuries without amputation (limb salvage, n = 107). Patient medical records were analyzed for four years postinjury. After adjusting for group differences, early amputation was generally associated with a lower or similar prevalence for adverse physical and psychological diagnoses (e.g., pain, osteoarthritis, posttraumatic stress disorder) versus late amputation and/or limb salvage. By contrast, early amputation was associated with an increased likelihood of osteoporosis during the first year postinjury. The prevalence of posttraumatic stress disorder increased for all patient groups over four years postinjury, particularly in the second year. The different clinical outcomes among combat extremity injured patients treated with early amputation, late amputation, or limb salvage highlight their different healthcare requirements. These findings can inform and optimize the specific treatment pathways that address the physical and psychological healthcare needs of such patients over time.
    MeSH term(s) Adult ; Amputation, Surgical/adverse effects ; Amputation, Surgical/psychology ; Humans ; Injury Severity Score ; Leg Injuries/psychology ; Leg Injuries/surgery ; Male ; Osteoporosis/etiology ; Osteoporosis/psychology ; Postoperative Complications/epidemiology ; Postoperative Complications/etiology ; Postoperative Complications/psychology ; Prevalence ; Prognosis ; Recovery of Function ; Stress Disorders, Post-Traumatic/etiology ; Stress Disorders, Post-Traumatic/psychology ; Surgical Wound Infection/epidemiology ; Surgical Wound Infection/etiology ; Time Factors ; United States ; Young Adult
    Language English
    Publishing date 2017-01-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0170569
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  7. Article ; Online: A Retrospective Comparison of Five-Year Health Outcomes Following Upper Limb Amputation and Serious Upper Limb Injury in the Iraq and Afghanistan Conflicts.

    Melcer, Ted / Walker, Jay / Sechriest, Vernon Franklin / Bhatnagar, Vibha / Richard, Erin / Perez, Katheryne / Galarneau, Michael

    PM & R : the journal of injury, function, and rehabilitation

    2019  Volume 11, Issue 6, Page(s) 577–589

    Abstract: Background: Limited population-based research has described long-term health outcomes following combat-related upper limb amputation.: Objective: To compare health outcomes following upper limb amputation with outcomes following serious upper limb ... ...

    Abstract Background: Limited population-based research has described long-term health outcomes following combat-related upper limb amputation.
    Objective: To compare health outcomes following upper limb amputation with outcomes following serious upper limb injury during the first 5 years postinjury.
    Design: Retrospective cohort.
    Setting: Departments of Defense (DoD) and Veterans Affairs (VA) inpatient and outpatient health care facilities.
    Participants: Three-hundred eighteen U.S. Service Members.
    Methods: Patients sustained an above elbow (AE, n = 51) or below elbow (BE, n = 80) amputation or serious arm injury without amputation (NO AMP, n = 187) in the Iraq or Afghanistan conflicts, 2001 through 2008. Injuries were coded by trauma nurses. Outcomes came from DoD and VA health databases.
    Main outcome measurements: International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) diagnostic codes.
    Results: Most patients were injured by blast weaponry causing serious to severe injuries. All groups had a high prevalence of physical and psychological health diagnoses. The prevalence for nearly all wound complications and many physical and psychological disorders decreased substantially after postinjury year 1. The prevalence of posttraumatic stress disorder, however, increased significantly from postinjury year 1 (20%) to 3 (36%). Pain and psychological disorders ranged from 69% to 90% of patients during postinjury year 1 and remained relatively high even postinjury during year 5 (37%-53%). After adjusting for covariates, the AE group had significantly higher odds for some physical and psychological diagnoses (eg, deep vein thrombosis/pulmonary embolism, cervical pain, osteoarthritis, obesity, and mood and adjustment disorders) relative to the BE or NO AMP groups. BE patients had significantly lower odds for osteomyelitis, and AE and BE patients had lower odds for fracture nonunion and joint disorders versus NO AMP.
    Conclusions: The results identify similarities and differences in clinical outcomes following combat-related upper limb amputation versus serious arm injury and can inform medical planning to improve rehabilitation programs and outcomes for these patients.
    Level of evidence: III.
    MeSH term(s) Adult ; Afghan Campaign 2001- ; Amputation, Traumatic/epidemiology ; Amputation, Traumatic/psychology ; Blast Injuries/epidemiology ; Blast Injuries/psychology ; Cohort Studies ; Fractures, Ununited/epidemiology ; Humans ; Iraq War, 2003-2011 ; Male ; Military Personnel ; Mood Disorders/epidemiology ; Neck Pain/epidemiology ; Obesity/epidemiology ; Osteoarthritis/epidemiology ; Osteomyelitis/epidemiology ; Pulmonary Embolism/epidemiology ; Retrospective Studies ; Stress Disorders, Post-Traumatic/epidemiology ; United States/epidemiology ; Upper Extremity/injuries ; Venous Thrombosis/epidemiology ; Warfare
    Language English
    Publishing date 2019-03-29
    Publishing country United States
    Document type Journal Article ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 2608988-9
    ISSN 1934-1563 ; 1934-1482
    ISSN (online) 1934-1563
    ISSN 1934-1482
    DOI 10.1002/pmrj.12047
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  8. Article ; Online: Correction

    Ted Melcer / Jay Walker / Vibha Bhatnagar / Erin Richard / V Franklin Sechriest Ii / Michael Galarneau

    PLoS ONE, Vol 12, Iss 2, p e

    A Comparison of Four-Year Health Outcomes following Combat Amputation and Limb Salvage.

    2017  Volume 0173214

    Abstract: This corrects the article DOI:10.1371/journal.pone.0170569.]. ...

    Abstract [This corrects the article DOI:10.1371/journal.pone.0170569.].
    Keywords Medicine ; R ; Science ; Q
    Language English
    Publishing date 2017-01-01T00:00:00Z
    Publisher Public Library of Science (PLoS)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    More links

    Kategorien

  9. Article ; Online: Lower-limb amputation and effect of posttraumatic stress disorder on Department of Veterans Affairs outpatient cost trends.

    Bhatnagar, Vibha / Richard, Erin / Melcer, Ted / Walker, Jay / Galarneau, Michael

    Journal of rehabilitation research and development

    2015  Volume 52, Issue 7, Page(s) 827–838

    Abstract: Department of Veterans Affairs (VA) outpatient costs were analyzed for combat Veterans injured in Iraq and Afghanistan from 2001 to 2008. Patients had serious lower-limb injuries (n = 170) or unilateral (n = 460) or bilateral (n = 153) lower-limb ... ...

    Abstract Department of Veterans Affairs (VA) outpatient costs were analyzed for combat Veterans injured in Iraq and Afghanistan from 2001 to 2008. Patients had serious lower-limb injuries (n = 170) or unilateral (n = 460) or bilateral (n = 153) lower-limb amputation(s). Total costs over the follow-up period (2003 to 2012) and annual costs were analyzed. Unadjusted mean costs per year in 2012 U.S. dollars were $7,200, $14,700 and $18,700 for limb injuries and unilateral and bilateral lower-limb amputation(s), respectively (p < 0.001). Multivariate modeling indicated that annual cost declined after the first year in the VA for Veterans with limb injuries (p < 0.001, repeated measures). In contrast, annual costs doubled after 3-5 years with unilateral (p < 0.001) and bilateral amputation(s) (p < 0.001). Among amputees, prosthetics comprised more than 50% of outpatient cost; unadjusted mean cost per year for prosthetics was 7-9 times higher in comparison with Veterans with limb injuries. Amputation status was associated with an adjusted 3.12-fold increase in mean prosthetic cost per year (p < 0.001, generalized linear model). In addition, posttraumatic stress disorder (PTSD) was associated with increased prosthetic cost by amputation status (p < 0.001) and increased psychiatric and pharmacy costs (both p < 0.001). Results indicate relatively high and sustained outpatient costs driven by prosthetics following amputation. Finally, PTSD affected cost for multiple domains of health, highlighting the importance of accurate diagnosis, treatment, and support for PTSD.
    MeSH term(s) Adult ; Afghan Campaign 2001- ; Amputation/economics ; Amputation/rehabilitation ; Amputees/rehabilitation ; Female ; Follow-Up Studies ; Health Care Costs/trends ; Humans ; Iraq War, 2003-2011 ; Lower Extremity/injuries ; Lower Extremity/surgery ; Male ; Middle Aged ; Outpatients ; Retrospective Studies ; Stress Disorders, Post-Traumatic/economics ; Stress Disorders, Post-Traumatic/etiology ; Stress Disorders, Post-Traumatic/rehabilitation ; United States ; Veterans ; Young Adult
    Language English
    Publishing date 2015
    Publishing country United States
    Document type Journal Article ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 605796-2
    ISSN 1938-1352 ; 0007-506X ; 0748-7711 ; 0742-3241 ; 0898-2732
    ISSN (online) 1938-1352
    ISSN 0007-506X ; 0748-7711 ; 0742-3241 ; 0898-2732
    DOI 10.1682/JRRD.2014.11.0288
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  10. Article ; Online: A Comparison of Four-Year Health Outcomes following Combat Amputation and Limb Salvage.

    Ted Melcer / Jay Walker / Vibha Bhatnagar / Erin Richard / V Franklin Sechriest / Michael Galarneau

    PLoS ONE, Vol 12, Iss 1, p e

    2017  Volume 0170569

    Abstract: Little research has described the long-term health outcomes of patients who had combat-related amputations or leg-threatening injuries. We conducted retrospective analysis of Department of Defense and Department of Veterans Affairs health data for lower ... ...

    Abstract Little research has described the long-term health outcomes of patients who had combat-related amputations or leg-threatening injuries. We conducted retrospective analysis of Department of Defense and Department of Veterans Affairs health data for lower extremity combat-injured patients with (1) unilateral amputation within 90 days postinjury (early amputation, n = 440), (2) unilateral amputation more than 90 days postinjury (late amputation, n = 78), or (3) leg-threatening injuries without amputation (limb salvage, n = 107). Patient medical records were analyzed for four years postinjury. After adjusting for group differences, early amputation was generally associated with a lower or similar prevalence for adverse physical and psychological diagnoses (e.g., pain, osteoarthritis, posttraumatic stress disorder) versus late amputation and/or limb salvage. By contrast, early amputation was associated with an increased likelihood of osteoporosis during the first year postinjury. The prevalence of posttraumatic stress disorder increased for all patient groups over four years postinjury, particularly in the second year. The different clinical outcomes among combat extremity injured patients treated with early amputation, late amputation, or limb salvage highlight their different healthcare requirements. These findings can inform and optimize the specific treatment pathways that address the physical and psychological healthcare needs of such patients over time.
    Keywords Medicine ; R ; Science ; Q
    Subject code 150
    Language English
    Publishing date 2017-01-01T00:00:00Z
    Publisher Public Library of Science (PLoS)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    More links

    Kategorien

To top