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  1. Book ; Online ; E-Book: Hand grasps and manipulation skills

    McCoy-Powlen, Jenna D. / Suarez, Michelle A. / Edwards, Sandra J. / Gallen, Donna B.

    clinical perspective of development and funtion

    2018  

    Author's details Sandra J. Edwards, Donna B. Gallen, Jenna D. McCoy-Powlen, Michelle A. Suarez
    Keywords Electronic books ; Hand Strength / physiology
    Language English
    Size 1 Online-Ressource (xx, 207 Seiten), Illustrationen, Diagramme
    Edition Second edition
    Publisher SLACK Incorporated
    Publishing place Thorofare, NJ
    Publishing country United States
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT021286432
    ISBN 978-1-63091-289-5 ; 978-1-63091-288-8 ; 9781630912871 ; 1-63091-289-1 ; 1-63091-288-3 ; 1630912875
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: Effect of Food Composition on the PK of Isoniazid Quantitatively Explained Using Physiologically Based Biopharmaceutics Modeling.

    Pepin, Xavier J H / Suarez-Sharp, Sandra

    The AAPS journal

    2024  Volume 26, Issue 3, Page(s) 54

    Abstract: This work shows the utilization of a physiologically based biopharmaceutics model (PBBM) to mechanistically explain the impact of diverse food types on the pharmacokinetics (PK) of isoniazid (INH) and acetyl-isoniazid (Ac-INH). The model was established ... ...

    Abstract This work shows the utilization of a physiologically based biopharmaceutics model (PBBM) to mechanistically explain the impact of diverse food types on the pharmacokinetics (PK) of isoniazid (INH) and acetyl-isoniazid (Ac-INH). The model was established and validated using published PK profiles for INH along with a combination of measured and predicted values for the physico-chemical and biopharmaceutical propertied of INH and Ac-INH. A dedicated ontogeny model was developed for N-acetyltransferase 2 (NAT2) in human integrating Michaelis Menten parameters for this enzyme in the physiologically based pharmacokinetic (PBPK) model tissues and in the gut, to explain the pre-systemic and systemic metabolism of INH across different acetylator types. Additionally, a novel equation was proposed to calculate the luminal drug degradation related to the presence of reducing sugars, using individual sugar molar concentrations in the meal. By incorporating luminal degradation into the model, adjusting bile salt concentrations and gastric emptying according to food type and quantity, the PBBM was able to accurately predict the negative effect of carbohydrate-rich diets on the PK of INH.
    MeSH term(s) Isoniazid/pharmacokinetics ; Isoniazid/administration & dosage ; Humans ; Models, Biological ; Food-Drug Interactions ; Antitubercular Agents/pharmacokinetics ; Antitubercular Agents/administration & dosage ; Arylamine N-Acetyltransferase/metabolism ; Biopharmaceutics/methods
    Chemical Substances Isoniazid (V83O1VOZ8L) ; Antitubercular Agents ; Arylamine N-Acetyltransferase (EC 2.3.1.5) ; NAT2 protein, human (EC 2.3.1.5)
    Language English
    Publishing date 2024-04-24
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 1550-7416
    ISSN (online) 1550-7416
    DOI 10.1208/s12248-024-00923-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Study of the Long-Term Aging of Polypropylene-Made Disposable Surgical Masks and Filtering Facepiece Respirators.

    Carreiras-Suárez, Sandra / Domínguez-Ramos, Lidia / Lazzari, Massimo

    Polymers

    2023  Volume 15, Issue 4

    Abstract: The main purpose of this work is to contribute to understanding the mechanism of oxidation of the polymeric components of common disposable masks used during the COVID-19 pandemic to offer the chemical basis to understand their long-term behavior under ... ...

    Abstract The main purpose of this work is to contribute to understanding the mechanism of oxidation of the polymeric components of common disposable masks used during the COVID-19 pandemic to offer the chemical basis to understand their long-term behavior under typical environmental conditions. Artificial aging of representative mask layers under isothermal conditions (110 °C) or accelerated photoaging showed that all the PP-made components underwent a fast oxidation process, following the typical hydrocarbon oxidation mechanism. In particular, yellowing and the melting temperature drop are early indicators of their diffusion-limited oxidation. Morphology changes also induced a loss of mechanical properties, observable as embrittlement of the fabric fibers. Results were validated through preliminary outdoor aging of masks, which allows us to predict they will suffer fast and extensive oxidation only in the case of contemporary exposure to sunlight and relatively high environmental temperature, leading to their extensive breakdown in the form of microfiber fragments, i.e., microplastics.
    Language English
    Publishing date 2023-02-17
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527146-5
    ISSN 2073-4360 ; 2073-4360
    ISSN (online) 2073-4360
    ISSN 2073-4360
    DOI 10.3390/polym15041001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Farianas, experiencias desde la insurgencia

    Dilia Consuelo Fuertes-Chaparro / Sandra Carolina Suárez-Quilaguy

    Revista CS, Iss

    2023  Volume 41

    Abstract: El interés del presente artículo fue realizar una aproximación a las experiencias de mujeres insurgentes de las Fuerzas Armadas Revolucionarias de Colombia - Ejército del Pueblo (FARC-EP) en el escenario del conflicto armado, antes de la firma del ... ...

    Abstract El interés del presente artículo fue realizar una aproximación a las experiencias de mujeres insurgentes de las Fuerzas Armadas Revolucionarias de Colombia - Ejército del Pueblo (FARC-EP) en el escenario del conflicto armado, antes de la firma del Acuerdo Final de Paz. Los referentes analíticos se enunciaron desde dos perspectivas: los estudios de paz y el feminismo. El abordaje metodológico fue cualitativo, a través de técnicas dialógicas con mujeres firmantes de paz en proceso de reincorporación. Se indagó acerca del rol de las mujeres en la transformación de las sociedades, la construcción de paz y las garantías de no repetición frente a los distintos tipos de violencias que confluyeron durante el conflicto armado en Colombia. Este trabajo recoge lo expresado por las mujeres con respecto a la igualdad, feminidad, vida comunitaria, maternidad y cuidado, todo lo anterior mediado por el contexto sociohistórico de la guerra en el país.
    Keywords feminismo ; conflicto armado ; FARC-EP ; mujer guerrillera ; Social Sciences ; H
    Language Spanish
    Publishing date 2023-12-01T00:00:00Z
    Publisher Universidad Icesi
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Where are the data to assess the safety of paternal drug exposure? A systematic review of secondary databases: A contribution from IMI concePTION.

    Gaitonde, Sneha / Moride, Yola / Suarez, Elizabeth / Lopez-Leon, Sandra

    Pharmacoepidemiology and drug safety

    2024  Volume 33, Issue 2, Page(s) e5764

    Abstract: Background: Most studies assessing the safety of parental drug exposures during pregnancy and around the time of conception describe the effects of maternal exposure. Recent publications have raised awareness of the need for additional research ... ...

    Abstract Background: Most studies assessing the safety of parental drug exposures during pregnancy and around the time of conception describe the effects of maternal exposure. Recent publications have raised awareness of the need for additional research regarding the safety of paternal drug exposures on pregnancy outcomes.
    Objectives: To identify and describe studies that use secondary databases in paternal drug safety studies and to describe the secondary databases that were used.
    Methods: A systematic review of studies assessing paternal medication exposure and pregnancy and infant outcomes using secondary databases was performed. In addition, the secondary databases used for these studies was described. Literature search was conducted using Embase, Web of Science, and PubMed, over the period January 1, 2012 to April 30, 2023. For each eligible study, paternal drug exposure, outcome, and data source characteristics were extracted in a data extraction form.
    Results: After reviewing the literature, 17 studies met inclusion criteria. The medications assessed for paternal safety were anti-rheumatic drugs (n = 10), anti-depressants (n = 3), anticonvulsants (n = 2), and anti-diabetes medications (n = 2). Pregnancy safety outcomes included congenital malformations, birth weight, and developmental disorders. The studies used five different databases across Europe and North America. The included studies used databases from Denmark (n = 12), Norway (n = 2), Sweden (n = 1), Canada (n = 1), and the United States (n = 1). The European studies utilized national patient registers that linked fathers to births and prescription histories. The North American databases used included insurance claims and electronic health records.
    Conclusions: Our review shows that few studies have been completed on paternal medication exposures and pregnancy outcomes, despite the availability of secondary databases that contain data necessary to link fathers to infants. More research on the potential adverse impacts of paternal medication exposures is needed.
    MeSH term(s) Female ; Humans ; Infant ; Male ; Pregnancy ; Birth Weight ; Fathers ; Paternal Exposure/adverse effects ; Pregnancy Outcome/epidemiology
    Language English
    Publishing date 2024-02-15
    Publishing country England
    Document type Systematic Review ; Journal Article ; Review
    ZDB-ID 1099748-9
    ISSN 1099-1557 ; 1053-8569
    ISSN (online) 1099-1557
    ISSN 1053-8569
    DOI 10.1002/pds.5764
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 3395: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (2.OG)
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  6. Article ; Online: The Inheritance of Daralgazi

    Sandra SUÁREZ GARCÍA

    Studia Historica. Historia Medieval, Vol 36, Iss 2, Pp 149-

    an Aristocratic Property in the Vega of Granada

    2019  Volume 170

    Abstract: In this essay we will analyze the characteristics of the inheritance of Daralgazi, located in the Vega of Granada, which Sancho de Castilla receives from the Catholic Monarchs in 1494, through a mercy granted for his merits in the War of Granada. ... ...

    Abstract In this essay we will analyze the characteristics of the inheritance of Daralgazi, located in the Vega of Granada, which Sancho de Castilla receives from the Catholic Monarchs in 1494, through a mercy granted for his merits in the War of Granada. Daralgazi is a property that passes from the holding of the «Moorish queens» to the hands of the Castilian-Aragonese monarchs during the time of the capitulations. We will focus on the characteristics of this property, the mention of it in other kinds of sources, and their nature and location. To sum up, all this topic will be inserted in the debate of the change of aristocratic property in the period of Conquest.
    Keywords propiedad ; aristocracia ; reino de granada ; almunia ; conquista ; History (General) and history of Europe ; D ; History (General) ; D1-2009 ; Medieval history ; D111-203
    Language English
    Publishing date 2019-01-01T00:00:00Z
    Publisher Ediciones Universidad de Salamanca
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Esquemas interpretativos de los actores en la escuela. Comprensiones desde el análisis del cambio organizacional

    Marlén Suárez Pineda / Luri Suárez Pineda / Sandra Milena Zambrano Vargas

    Revista de Ciencias Sociales, Vol 28, Iss

    2022  Volume 3

    Abstract: Las organizaciones institucionalizadas sacrifican el cumplimiento de la misión para mostrarse cumplidoras de lógicas y prescripciones legitimadoras en su campo organizacional. Esta investigación pretende entender cómo han cambiado los esquemas ... ...

    Abstract Las organizaciones institucionalizadas sacrifican el cumplimiento de la misión para mostrarse cumplidoras de lógicas y prescripciones legitimadoras en su campo organizacional. Esta investigación pretende entender cómo han cambiado los esquemas interpretativos de los sujetos en el ambiente escolar, como consecuencia de las presiones por la calidad provenientes del campo de la educación. Las comprensiones se buscan desde una perspectiva crítica de las teorías tradicionales de la organización, en donde se superan determinismos simplificadores. La metodología es cualitativa, de corte fenomenológico, utilizando como método el estudio de caso múltiple con organizaciones escolares de los niveles básica y media de la educación pública en la ciudad de Tunja, Colombia. Las técnicas utilizadas son la entrevista semiestructurada, el focus group, la observación no participante y el análisis documental. Los resultados ofrecen evidencia empírica de que los sujetos organizacionales se comportan debidamente para legitimar la organización escuela, aunque haya ausencia de construcción de sentido en torno a las prescripciones de las políticas educativas. Se concluye que los arreglos dominantes en el campo de la educación han transformado la realidad de la escuela, promoviendo el apego a mitos racionalizados en menoscabo de la autonomía para resolver demandas propias de los entornos escolares.
    Keywords escuela ; calidad de la educación ; organización institucionalizada ; esquemas interpretativos ; cambio organizacional ; Political science (General) ; JA1-92 ; Social sciences (General) ; H1-99
    Language Spanish
    Publishing date 2022-07-01T00:00:00Z
    Publisher Universidad del Zulia
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Thesis ; Online: Impacto en la industria de alimentos a causa de la pandemia por Covid 19

    Suárez Amaya, Sandra Milena

    2020  

    Abstract: Ensayo seminario internacional ... Dado el momento histórico por el que atraviesa el mundo por la pandemia ocasionada por el virus Covid 19, se narra sobre los cambios en que deberían incurrir las industrias, en especial la de alimentos. Se revisan las ... ...

    Abstract Ensayo seminario internacional

    Dado el momento histórico por el que atraviesa el mundo por la pandemia ocasionada por el virus Covid 19, se narra sobre los cambios en que deberían incurrir las industrias, en especial la de alimentos. Se revisan las acciones que debería tomar la industria de alimentos para mitigar el impacto causado por la pandemia y se describe la experiencia una empresa en Bogotá.

    TÍTULO DEL ENSAYO AUTOR FRASE CELEBRE REFERENCIAS BIBLIOGRÁFICAS
    Keywords HACCP ; COVID 19 ; INDUSTRIA DE ALIMENTOS ; covid19
    Language Spanish
    Publishing country co
    Document type Thesis ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Book ; Online: Aportes analíticos al estudio de aguas residuales y potables

    Castillo Ayala, Jorge Enrique / Pineda Quintero, Alejandra / Castro Narváez, Sandra Patricia / Martán Rodríguez, Carol Stephania / Nazaritt Escobar, Diana / Valencia Velandia, Natalia Andrea / Rios Acevedo, Jhon Jairo / Castillo Suárez, Carolina / Manzano Lozano, Jhonny Randall / Garzón García, Guillermo / Burbano Banguero, Diana Marcela / Carabali Yepes, Jorge Humberto / López Parra, Lizbeth Lorena / Jiménez Ortiz, Rafael

    2020  

    Keywords Sewage treatment & disposal ; Precisión ; Linealidad ; Validación ; Espectrofotometría ; Metales ; Agua potable ; Trazabilidad ; Espectroscopia UV-Vis ; Potabilización ; Sólidos disueltos ; Coagulantes ; Floculantes ; pH ; Aguas residuales ; Ingenio azucarero ; Laguna facultativa
    Language 0|s
    Size 1 electronic resource (1-194 pages)
    Publisher Universidad Santiago de Cali
    Publishing place Colombia
    Document type Book ; Online
    Note Spanish ; Open Access
    HBZ-ID HT021618608
    ISBN 978-958-5583-21-4 ; 958-5583-21-6
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  10. Article ; Online: Sociodemographic and psycho social Differences Between Hate Crime Offenders and Other Non-Bias-Motivated Criminals: Implications for Prison Rehabilitation Programs.

    Pérez Ramírez, Meritxell / Chiclana, Sandra / Méndez, Raquel C / Suárez, Ana

    International journal of offender therapy and comparative criminology

    2022  , Page(s) 306624X221132235

    Abstract: Hate crimes have severe consequences for the victims and for all members of the victim's social category. Prison programs must address the criminogenic needs of the participants, especially in this kind of crime, in order to prevent recidivism. This ... ...

    Abstract Hate crimes have severe consequences for the victims and for all members of the victim's social category. Prison programs must address the criminogenic needs of the participants, especially in this kind of crime, in order to prevent recidivism. This study seeks to understand the role of prejudice and aggression in the execution of hate crimes, in order to design effective interventions for hate crime offenders. Sociodemographic, criminological, and psychosocial variables were assessed in a sample of 33 hate crime offenders sentenced to prison or community service and in a group of 38 non-bias-motivated criminals (
    Language English
    Publishing date 2022-11-13
    Publishing country United States
    Document type Journal Article
    ZDB-ID 218274-9
    ISSN 1552-6933 ; 0306-624X
    ISSN (online) 1552-6933
    ISSN 0306-624X
    DOI 10.1177/0306624X221132235
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 1496: Show issues Location:
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