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  1. Book ; Online: Application of Retinal and Optic Nerve Imaging in Clinical Medicine 2.0

    Mastropasqua, Rodolfo / D'Aloisio, Rossella

    2023  

    Keywords Medicine ; Pharmacology ; rhegmatogenous retinal detachment ; optical coherence tomography angiography ; vitrectomy ; foveal avascular zone ; macular vessel density ; Boswellia serrata ; curcumin ; diabetic macular edema ; celiac disease ; OCT ; optical coherence tomography ; retinal layers ; RNFL ; quality of life ; canaloplasty ; trabeculectomy ; medical therapy ; central serous chorioretinopathy ; pachychoroid ; en face optical coherence tomography ; choroid ; choroidal vascularity index ; oculomics ; artificial intelligence ; machine learning ; deep learning ; retinal imaging ; color fundus photograph ; systemic diseases ; cardiovascular diseases ; neurodegenerative diseases ; COVID ; SARS-CoV-2 ; retinal vein occlusion ; RVO ; vaccination ; branch retinal vein occlusion ; optic disc drusen ; visible optic disc drusen ; deep convolutional neural network ; DCNN ; inceptionv3 ; dyslexia ; reading ; retina ; macula ; fovea ; parafovea ; perifovea ; thickness ; segmentation ; Best disease ; choroideremia ; inherited retinal diseases ; retinitis pigmentosa ; Stargardt disease
    Language English
    Size 1 electronic resource (114 pages)
    Publisher MDPI - Multidisciplinary Digital Publishing Institute
    Publishing place Basel
    Document type Book ; Online
    Note English
    HBZ-ID HT030646137
    ISBN 9783036591810 ; 3036591818
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article: Macular Surgery: Classification, Management and Surgical Techniques.

    Forlini, Matteo / Rizzo, Stanislao / Rejdak, Robert / Natarajan, Sundaram / Avitabile, Teresio / Mastropasqua, Rodolfo

    Journal of ophthalmology

    2023  Volume 2023, Page(s) 9891345

    Language English
    Publishing date 2023-01-16
    Publishing country United States
    Document type Editorial
    ZDB-ID 2546525-9
    ISSN 2090-0058 ; 2090-004X
    ISSN (online) 2090-0058
    ISSN 2090-004X
    DOI 10.1155/2023/9891345
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Different Methods of Secondary Intraocular Lens Implantation.

    Forlini, Matteo / Malyugin, Boris / Ahmed, Ike / Scharioth, Gabor / Mastropasqua, Rodolfo / Mularoni, Alessandro

    Journal of ophthalmology

    2023  Volume 2023, Page(s) 9847067

    Language English
    Publishing date 2023-12-19
    Publishing country United States
    Document type Editorial
    ZDB-ID 2546525-9
    ISSN 2090-0058 ; 2090-004X
    ISSN (online) 2090-0058
    ISSN 2090-004X
    DOI 10.1155/2023/9847067
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Bilateral Branch Retinal Vein Occlusion after mRNA-SARS-CoV-2 Booster Dose Vaccination.

    Gironi, Matteo / D'Aloisio, Rossella / Verdina, Tommaso / Shkurko, Benjamin / Toto, Lisa / Mastropasqua, Rodolfo

    Journal of clinical medicine

    2023  Volume 12, Issue 4

    Abstract: Purpose: We report a case of a patient with a bilateral branch retinal vein occlusion (BRVO) 24 h after a booster vaccination with the mRNA-1237 vaccine.: Observations: Fluorescein angiography, performed at three weeks follow-up, showed vascular ... ...

    Abstract Purpose: We report a case of a patient with a bilateral branch retinal vein occlusion (BRVO) 24 h after a booster vaccination with the mRNA-1237 vaccine.
    Observations: Fluorescein angiography, performed at three weeks follow-up, showed vascular leakage and blockage, corresponding to hemorrhage areas associated with ischemic areas in the macula and along the arcades involved in the occlusion.
    Conclusions: The patient was scheduled for urgent injections of intravitreal ranibizumab and laser photocoagulation of the ischemic areas. To the best of our knowledge, this is the first case described of concomitant bilateral RVO after COVID-19 vaccination. The rapid onset of the side effects in a patient with multiple risk factors for thrombotic events suggests that vulnerable microvascular conditions require detailed investigations before administration of a COVID-19 vaccine.
    Language English
    Publishing date 2023-02-07
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm12041325
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Analysis of Macular Pigment Optical Density in Macular Holes with Different Border Phenotypes.

    Quarta, Alberto / Gironi, Matteo / Ruggeri, Maria Ludovica / Porreca, Annamaria / D'Aloisio, Rossella / Toto, Lisa / Di Nicola, Marta / Mastropasqua, Rodolfo

    Ophthalmology and therapy

    2024  Volume 13, Issue 2, Page(s) 571–580

    Abstract: Introduction: We conducted a cross-sectional study to compare macular pigment optical density (MPOD) in eyes with idiopathic macular holes with bumpy (bbMH) and smooth borders (sbMH) and to assess the relation between MPOD and optical coherence ... ...

    Abstract Introduction: We conducted a cross-sectional study to compare macular pigment optical density (MPOD) in eyes with idiopathic macular holes with bumpy (bbMH) and smooth borders (sbMH) and to assess the relation between MPOD and optical coherence tomography findings. Thirty eyes from thirty patients affected by idiopathic macular hole were studied.
    Methods: All patients underwent SD-OCT and macular pigment optical density (MPOD) analysis. Comparison between the two border phenotypes were estimated at baseline, as well as  the differences in MPOD, minimum and basal hole diameter, tractional hole index (THI), macular hole index (MHI), diameter hole index (DHI), and ELM integrity metrics between the two groups.
    Results: The mean MPOD was 0.09 ± 0.08 in bbMHs and 0.16 ± 0.11 in sbMHs (p = 0.010). Correlation analysis between MPOD and minimum hole  diameter revealed a negative association (rho = - 0.707, p = 0.008) in bbMH and a positive association (rho = 0.702, p = 0.019) in sbMH. MPOD and basal diameter were negatively correlated in bbMH (rho = - 0.77, p = 0.001) and positively correlated in sbMH (rho = 0.675, p = 0.019). Indeed, MPOD is negatively correlated with THI and MHI in sbMH (rho = - 0.684 p = 0.019; rho = - 0.665 p = 0.019, respectively) and positively correlated in bbMH (rho = 0.593 p = 0.037; rho = 0.658 p = 0.018, respectively).
    Conclusions: MPOD is significantly reduced in bbMHs compared to sbMHs. The two border phenotypes also differ for tractional and tangential indexes, possibly reflecting a different pathogenesis. Further studies are needed to understand the prognostic role of MPOD.
    Language English
    Publishing date 2024-01-04
    Publishing country England
    Document type Journal Article
    ISSN 2193-8245
    ISSN 2193-8245
    DOI 10.1007/s40123-023-00874-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Micropulse Laser Trabeculoplasty with 577 nm Wavelength at 1500 or 1000 mW for Primary Open-Angle Glaucoma: A Pilot Study.

    Verdina, Tommaso / Gironi, Matteo / Battaglia, Bruno / Gentile, Michele / Chester, Johanna / Kaleci, Shaniko / Scatigna, Gianluca / Mastropasqua, Rodolfo / Cavallini, Gian Maria

    Life (Basel, Switzerland)

    2023  Volume 13, Issue 4

    Abstract: ... ...

    Abstract Aim
    Language English
    Publishing date 2023-04-10
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662250-6
    ISSN 2075-1729
    ISSN 2075-1729
    DOI 10.3390/life13040982
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Acute transient macular detachment after uneventful cataract surgery in a highly myopic eye.

    Verdina, Tommaso / Caporossi, Tomaso / Cavallini, Gian Maria / Mastropasqua, Rodolfo

    American journal of ophthalmology case reports

    2021  Volume 22, Page(s) 101117

    Abstract: Purpose: We report a case of a highly myopic patient who presented a serous macular detachment at 24 hours after uncomplicated cataract surgery.: Observations: Surprisingly, after six days from surgery, a reabsorption of the detachment was noticed ... ...

    Abstract Purpose: We report a case of a highly myopic patient who presented a serous macular detachment at 24 hours after uncomplicated cataract surgery.
    Observations: Surprisingly, after six days from surgery, a reabsorption of the detachment was noticed and the macular area returned to be anatomically normal without any surgical intervention. This early postoperative complication could be caused by changes in the vitreoretinal interface and ocular fluid dynamics or to a rupture of blood-retinal barriers due to postoperative inflammation.
    Conclusions and importance: Our case reports on the occurrence of an early transient macular detachment after uneventful cataract surgery in a highly myopic eye. This finding suggests the importance of an OCT-based control in the immediate postoperative hours.
    Language English
    Publishing date 2021-05-06
    Publishing country United States
    Document type Case Reports
    ISSN 2451-9936
    ISSN (online) 2451-9936
    DOI 10.1016/j.ajoc.2021.101117
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Anti-VEGF Therapy in Myopic CNV.

    Toto, Lisa / Di Antonio, Luca / Costantino, Olivia / Mastropasqua, Rodolfo

    Current drug targets

    2021  Volume 22, Issue 9, Page(s) 1054–1063

    Abstract: In this narrative-review, we report the most recent data from the literature of anti-vascular endothelial growth factor treatment for myopic choroidal neovascularization (mCNV). Myopic CNV is the most frequent sight-threatening complication of pathologic ...

    Abstract In this narrative-review, we report the most recent data from the literature of anti-vascular endothelial growth factor treatment for myopic choroidal neovascularization (mCNV). Myopic CNV is the most frequent sight-threatening complication of pathologic myopia. The natural course of mCNV can result in expanding macular atrophy and /or fibrosis, leading to irreversible visual loss after 5 years. Retinal multimodal imaging is mandatory for early diagnosis and monitoring of the disease during treatment. Intravitreal anti-vascular endothelial growth factor (anti-VEGF) therapy is recommended as the first-line treatment option for mCNV. Prompt treatment of active mCNV with intravitreal anti-VEGF therapy has been demonstrated to be effective in terms of visual outcome improvements reducing the occurrence of late-stage complications.
    MeSH term(s) Angiogenesis Inhibitors/therapeutic use ; Bevacizumab/therapeutic use ; Choroidal Neovascularization/drug therapy ; Humans ; Intravitreal Injections ; Myopia, Degenerative/complications ; Myopia, Degenerative/drug therapy ; Ranibizumab ; Vascular Endothelial Growth Factor A/antagonists & inhibitors ; Visual Acuity
    Chemical Substances Angiogenesis Inhibitors ; Vascular Endothelial Growth Factor A ; Bevacizumab (2S9ZZM9Q9V) ; Ranibizumab (ZL1R02VT79)
    Language English
    Publishing date 2021-01-29
    Publishing country United Arab Emirates
    Document type Journal Article ; Review
    ZDB-ID 2064859-5
    ISSN 1873-5592 ; 1389-4501
    ISSN (online) 1873-5592
    ISSN 1389-4501
    DOI 10.2174/1389450122999210128180725
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5578: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  9. Article ; Online: Structural and Molecular Tear Film Changes in Glaucoma.

    Mastropasqua, Rodolfo / Agnifili, Luca / Mastropasqua, Leonardo

    Current medicinal chemistry

    2018  Volume 26, Issue 22, Page(s) 4225–4240

    Abstract: The Tear Film (TF) is a trilaminar and dynamic fluid covering the entire Ocular Surface (OS), consisting of a mucus, aqueous, and lipid layer deeply interacting between them. Because of its structure and functions, TF plays a pivotal role in the ... ...

    Abstract The Tear Film (TF) is a trilaminar and dynamic fluid covering the entire Ocular Surface (OS), consisting of a mucus, aqueous, and lipid layer deeply interacting between them. Because of its structure and functions, TF plays a pivotal role in the preservation of the OS integrity and the quality of vision. Medical therapy for glaucoma is recognized to profoundly disturb the OS homeostasis by altering all components of the ocular surface unit, including TF. The presence of preservatives, the number of daily eye drops instillations, and the duration of therapy are the main contributors to TF changes. From the physio-pathological side, TF alterations are induced by toxic and allergic mechanisms and result from goblet cell and Meibomian gland loss, dysfunction of accessory lacrimal glands, and epithelial disruption. In detail, TF changes are represented by mucus layer thinning, reduced mucin concentration, aqueous layer volume reduction, and lipid layer thinning with increased tear evaporation. Hyper- osmolarity and instability represent the main hallmarks of these changes and are an expression of a iatrogenic form of dry eye. TF undergoes also molecular modifications that primarily reflect a therapy- or disease-induced inflammatory status of the OS. Over the last years, this field of research aimed a progressively growing interest since molecular variations may be considered as potential candidate biomarkers of glaucoma. The aim of this review is to report the main TF changes occurring during glaucoma, exploring the relationship they may have with the glaucoma-related ocular surface disease and the patient quality of life, and their utility as potential biomarkers of disease.
    MeSH term(s) Animals ; Antihypertensive Agents/chemistry ; Antihypertensive Agents/pharmacology ; Corneal Diseases/drug therapy ; Glaucoma/drug therapy ; Humans ; Molecular Structure ; Preservatives, Pharmaceutical/chemistry ; Preservatives, Pharmaceutical/pharmacology ; Tears/drug effects
    Chemical Substances Antihypertensive Agents ; Preservatives, Pharmaceutical
    Language English
    Publishing date 2018-10-10
    Publishing country United Arab Emirates
    Document type Journal Article ; Review
    ZDB-ID 1319315-6
    ISSN 1875-533X ; 0929-8673
    ISSN (online) 1875-533X
    ISSN 0929-8673
    DOI 10.2174/0929867325666181009153212
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4432: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  10. Article: Beauveria bassiana keratitis: Management of an atypical clinical presentation.

    Ducange, Pietro / Verdina, Tommaso / Stiro, Fabio / Grottola, Antonella / Orlando, Gabriella / Delvecchio, Giancarlo / Mastropasqua, Rodolfo

    Medical mycology case reports

    2021  Volume 33, Page(s) 1–4

    Abstract: We report an atypical presentation ... ...

    Abstract We report an atypical presentation of
    Language English
    Publishing date 2021-05-25
    Publishing country Netherlands
    Document type Case Reports
    ISSN 2211-7539
    ISSN 2211-7539
    DOI 10.1016/j.mmcr.2021.05.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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