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Article ; Online: Gender differences in diet quality and the association between diet quality and BMI: an analysis in young Australian adults who completed the Healthy Eating Quiz.

Fenton, Sasha / Ashton, Lee M / Lee, Daniel C W / Collins, Clare E

Journal of human nutrition and dietetics : the official journal of the British Dietetic Association

2024

Abstract: ... of 25.9 ± 5.0 years and BMI of 24.6 ± 5.2 kg/m: Conclusion: Interventions that target young adults ...

Abstract	Background: Many young adults report poor diet quality. However, research evaluating whether young adult males and females differ in diet quality is limited. Additionally, although diet quality has a known inverse association with body mass index (BMI), it is unclear whether this association is observed in young adults and whether it varies by gender. The present study aimed to evaluate gender differences in diet quality in young adults, as well as the associations between diet quality and BMI. Methods: Data collected via the Healthy Eating Quiz (HEQ) in respondents aged 18-35 years between July 2019 and December 2021 were analysed, including demographics, and diet quality calculated using the Australian Recommended Food Score (ARFS). Differences in characteristics were analysed using a two-sample t-test, chi-squared and one-way analysis of covariance. Linear regressions were performed to estimate associations between diet quality and BMI. An interaction term was included in the model to test differences between genders. Results: The respondents (n = 28,969) were predominantly female (70.8%) with a mean ± SD age of 25.9 ± 5.0 years and BMI of 24.6 ± 5.2 kg/m Conclusion: Interventions that target young adults are needed to improve diet quality and its potential contribution to BMI status. As a result of the small observed effect sizes, caution should be applied in interpreting these findings.
Language	English
Publishing date	2024-04-25
Publishing country	England
Document type	Journal Article
ZDB-ID	645183-4
ISSN	1365-277X ; 0952-3871 ; 1465-8178
ISSN (online)	1365-277X
ISSN	0952-3871 ; 1465-8178
DOI	10.1111/jhn.13309
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: The effectiveness of the TRACE online nutrition intervention in improving dietary intake, sleep quality and physical activity levels for Australian adults with food addiction: a randomised controlled trial.

Leary, Mark / Skinner, Janelle A / Pursey, Kirrilly M / Verdejo-Garcia, Antonio / Collins, Rebecca / Collins, Clare / Hay, Phillipa / Burrows, Tracy L

Journal of human nutrition and dietetics : the official journal of the British Dietetic Association

2024

Abstract: ... at 3 months.: Methods: Adults with ≥3 symptoms of FA and a body mass index > 18.5 kg/m: Results ...

Abstract	Background: Few interventions for food addiction (FA) report on dietary intake variables. The present study comprised a three-arm randomised controlled trial in adults with symptoms of FA. The aim was to evaluate dietary intake, sleep and physical activity resulting from a dietitian-led telehealth intervention at 3 months. Methods: Adults with ≥3 symptoms of FA and a body mass index > 18.5 kg/m Results: The active intervention group was superior compared to the passive intervention and control groups for improvements in percent energy from core (6.4%/day [95% confidence interval (CI) -0.0 to 12.9], p = 0.049), non-core foods (-6.4%/day [95% CI -12.9 to 0.0], p = 0.049), sweetened drinks (-1.7%/day [95% CI -2.9 to -0.4], p = 0.013), takeaway foods (-2.3%/day [95% CI -4.5 to -0.1], p = 0.045) and sodium (-478 mg/day [95% CI -765 to -191 mg], p = 0.001). Conclusions: A dietitian-led telehealth intervention for Australian adults with FA found significant improvements in dietary intake variables. Setting personalised goals around nutrition and eating behaviours was beneficial for lifestyle change.
Language	English
Publishing date	2024-04-23
Publishing country	England
Document type	Journal Article
ZDB-ID	645183-4
ISSN	1365-277X ; 0952-3871 ; 1465-8178
ISSN (online)	1365-277X
ISSN	0952-3871 ; 1465-8178
DOI	10.1111/jhn.13312
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Article ; Online: Resilience in caregivers of people with mild-to-moderate dementia: findings from the IDEAL cohort.

Martyr, Anthony / Rusted, Jennifer M / Quinn, Catherine / Gamble, Laura D / Collins, Rachel / Morris, Robin G / Clare, Linda

BMC geriatrics

2023 Volume 23, Issue 1, Page(s) 804

Abstract: Objectives: A novel model of resilience was tested in caregivers of people with mild-to-moderate dementia and was extended to explore whether including self-efficacy, optimism, and self-esteem improved its predictive value.: Design: Cross-sectional.!# ...

Abstract	Objectives: A novel model of resilience was tested in caregivers of people with mild-to-moderate dementia and was extended to explore whether including self-efficacy, optimism, and self-esteem improved its predictive value. Design: Cross-sectional. Setting: Data from the IDEAL cohort were used. Participants: The study comprised 1222 caregivers of people with dementia. Measurements: A composite resilience score was calculated from five measures. Multivariable regressions were used to investigate factors associated with resilience. Results: Greater resilience was associated with being older, being male, and caregiving for older people with dementia. Greater resilience was also observed when people with dementia had fewer functional difficulties and/or fewer neuropsychiatric symptoms, there was a stronger dyadic relationship, and the caregiver had fewer social restrictions, less neuroticism, and greater perceived competence. Surprisingly, caregiver self-efficacy, optimism, and self-esteem were unrelated to resilience. Conclusion: Caregivers of people with mild-to-moderate dementia generally scored well for resilience. Resilience was associated with both the personal characteristics of caregivers and level of care need among people with dementia. Future work is needed to determine whether the caregivers in this cohort appeared resilient because the care recipients had relatively low care needs and consequently placed fewer demands on caregiver well-being than would be the case where dementia is more advanced.
MeSH term(s)	Humans ; Male ; Aged ; Female ; Caregivers/psychology ; Cross-Sectional Studies ; Dementia/psychology ; Self Efficacy ; Self Concept
Language	English
Publishing date	2023-12-05
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2059865-8
ISSN	1471-2318 ; 1471-2318
ISSN (online)	1471-2318
ISSN	1471-2318
DOI	10.1186/s12877-023-04549-y
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Article: Healthcare Professionals' Perspectives of Nonsurgical Care of Older Inpatients with Class II or III Obesity and Comorbidities: A Qualitative Study.

Rees, Merridie / Collins, Clare E / Majellano, Eleanor C / McDonald, Vanessa M

Journal of multidisciplinary healthcare

2023 Volume 16, Page(s) 3339–3355

Abstract: Background: Older people with Class II or III obesity and comorbidities experience complex care needs with frequent hospital admissions. In 2019/20 the National Health Service in England reported a 17% increase in hospital admissions of patients with ... ...

Abstract	Background: Older people with Class II or III obesity and comorbidities experience complex care needs with frequent hospital admissions. In 2019/20 the National Health Service in England reported a 17% increase in hospital admissions of patients with obesity compared to 2018/19. Gaps in care for this population have been identified. Purpose: The purpose of this study was to understand the experiences and perspectives of healthcare professionals delivering non-surgical care to older people with Classes II or III obesity admitted to a tertiary care hospital. Methods: Healthcare professionals delivering non-surgical care to older people admitted with Class II or III obesity with comorbidities were recruited from an Australian tertiary referral hospital. Qualitative semi-structured interviews were conducted with 24 healthcare professionals from seven disciplines between August and December 2019. The interviews were audio-recorded, transcribed, and reviewed by participants for accuracy. Thematic inductive data analysis was deductively mapped to the Theoretical Domains Framework (TDF). Results: Four major themes of Barriers, Facilitators, Current Practice, and Recommendations and 11 subthemes were identified and mapped to nine domains in the TDF. The Barriers subtheme identified perceived patient related factors, health system issues, and provider issues, while the Facilitators subtheme included a patient centred approach, knowledge, and resources in the subacute setting. The major Current Practice theme explored factors influencing clinical management, and the Recommendations subthemes included engaging patients, access to quality care, education and support, and obesity as a chronic disease. Conclusion: This novel application of the TDF provided broad insights related to the barriers and facilitators in delivering non-surgical care to this hospital population, from the perspective of healthcare professionals. Understanding how these barriers interact can provide strategies to influence behaviour change and assist in the development of a holistic multidisciplinary model of care.
Language	English
Publishing date	2023-11-08
Publishing country	New Zealand
Document type	Journal Article
ZDB-ID	2453343-9
ISSN	1178-2390
ISSN	1178-2390
DOI	10.2147/JMDH.S421520
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Article ; Online: Gender differences in social desirability and approval biases, and associations with diet quality in young adults.

Tang, Jei Sey / Haslam, Rebecca L / Ashton, Lee M / Fenton, Sasha / Collins, Clare E

Appetite

2022 Volume 175, Page(s) 106035

Abstract: ... median age 21.7 years, BMI 24.7 kg/m ...

Abstract	Social desirability and approval biases can influence self-report of diet, contributing to inaccurate assessment. Biases may be influenced by sex. This study examined gender differences in social desirability and approval, and diet quality in young adults, and relationships between social biases and diet quality. Data from 1003 young adults participating in the Advice, Ideas and Motivation for My Eating trial, median age 21.7 years, BMI 24.7 kg/m
Language	English
Publishing date	2022-04-09
Publishing country	England
Document type	Journal Article
ZDB-ID	1461347-5
ISSN	1095-8304 ; 0195-6663
ISSN (online)	1095-8304
ISSN	0195-6663
DOI	10.1016/j.appet.2022.106035
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Article ; Online: Cerebral Malaria Is Regulated by Host-Mediated Changes in

Cimperman, Clare K / Pena, Mirna / Gokcek, Sohret M / Theall, Brandon P / Patel, Meha V / Sharma, Anisha / Qi, ChenFeng / Sturdevant, Daniel / Miller, Louis H / Collins, Patrick L / Pierce, Susan K / Akkaya, Munir

mBio

2023 Volume 14, Issue 2, Page(s) e0339122

Abstract: Cerebral malaria (CM), the deadliest complication ... ...

Abstract	Cerebral malaria (CM), the deadliest complication of
MeSH term(s)	Animals ; Mice ; Malaria, Cerebral/parasitology ; Plasmodium berghei/physiology ; Mice, Inbred C57BL ; Gene Expression ; Disease Models, Animal
Language	English
Publishing date	2023-02-28
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, N.I.H., Intramural
ZDB-ID	2557172-2
ISSN	2150-7511 ; 2161-2129
ISSN (online)	2150-7511
ISSN	2161-2129
DOI	10.1128/mbio.03391-22
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Article ; Online: An online qualitative study exploring wants and needs for a cooking programme during pregnancy in the UK and Ireland.

Lavelle, Fiona / McKernan, Claire / Shrewsbury, Vanessa / Wolfson, Julia A / Taylor, Rachael M / Duncanson, Kerith / Martins, Carla A / Elliott, Christopher / Collins, Clare E

Journal of human nutrition and dietetics : the official journal of the British Dietetic Association

2024

Abstract: Background: Optimal maternal nutrition is associated with better pregnancy and infant outcomes. Culinary nutrition programmes have potential to improve diet quality during pregnancy. Therefore, this research aimed to understand the experiences of ... ...

Abstract	Background: Optimal maternal nutrition is associated with better pregnancy and infant outcomes. Culinary nutrition programmes have potential to improve diet quality during pregnancy. Therefore, this research aimed to understand the experiences of cooking and the wants and needs of pregnant women regarding a cooking and food skills programme in the United Kingdom (UK) and Republic of Ireland (ROI). Methods: Online focus group discussions with pregnant women and those who had experienced a pregnancy in the UK or ROI were conducted between February and April 2022. Two researchers conducted a thematic analysis. Seven focus groups with ROI participants (n = 24) and six with UK participants (n = 28) were completed. Results: Five themes were generated. These were (1) cooking during pregnancy: barriers, motivators and solutions; (2) food safety, stress and guilt; (3) need for cooking and food skills programmes and desired content; (4) programme structure; (5) barriers and facilitators to programme participation. Overall, there was support for a programme focusing on broad food skills, including planning, food storage, using leftovers and to manage pregnancy-specific physiological symptoms such as food aversions. Participants emphasised the importance of inclusivity for a diverse range of people and lifestyles for programme design and content. Conclusions: Current findings support the use of digital technologies for culinary nutrition interventions, potentially combined with in-person sessions using a hybrid structure to enable the development of a support network.
Language	English
Publishing date	2024-04-12
Publishing country	England
Document type	Journal Article
ZDB-ID	645183-4
ISSN	1365-277X ; 0952-3871 ; 1465-8178
ISSN (online)	1365-277X
ISSN	0952-3871 ; 1465-8178
DOI	10.1111/jhn.13307
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Zs.A 2551: Show issues

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ab Jg. 2022: Lesesaal (EG)

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Article ; Online: A three-arm randomised controlled trial of a telehealth intervention targeting improvement in addictive eating for Australian adults (the TRACE program).

Skinner, Janelle A / Leary, Mark / Whatnall, Megan / Collins, Rebecca A / Pursey, Kirrilly M / Verdejo-Garcia, Antonio / Hay, Phillipa J / Baker, Amanda L / Hides, Leanne / Paxton, Susan J / Wood, Lisa G / Colyvas, Kim / Collins, Clare E / Burrows, Tracy L

Appetite

2024 Volume 195, Page(s) 107211

Abstract: There is a substantial research base for addictive eating with development of interventions. The current 3-arm RCT aimed to investigate the efficacy of the TRACE (Targeted Research for Addictive and Compulsive Eating) program to decrease addictive eating ...

Abstract	There is a substantial research base for addictive eating with development of interventions. The current 3-arm RCT aimed to investigate the efficacy of the TRACE (Targeted Research for Addictive and Compulsive Eating) program to decrease addictive eating symptoms and improve mental health. Participants (18-85 yrs) endorsing ≥3 addictive eating symptoms were randomly allocated to 1) active intervention, 2) passive intervention, or 3) control group. Primary outcome was change in addictive eating symptoms 3-months post-baseline measured by the Yale Food Addiction Scale. Depression, anxiety and stress were also assessed. A total of 175 individuals were randomised. Using Linear Mixed Models, from baseline to 3-months, there was significant improvement in symptom scores in all groups with mean decrease of 4.7 (95% CI: -5.8, -3.6; p < 0.001), 3.8 (95% CI: -5.2, -2.4; p < 0.001) and 1.5 (95% CI: -2.6, -0.4; p = 0.01) respectively. Compared with the control group, participants in the active intervention were five times more likely to achieve a clinically significant change in symptom scores. There was a significant reduction in depression scores in the active and passive intervention groups, but not control group [-2.9 (95% CI: -4.5, -1.3); -2.3 (95% CI: -4.3, -0.3); 0.5 (95% CI: -1.1, 2.1), respectively]; a significant reduction in stress scores within the active group, but not passive intervention or control groups [-1.3 (95% CI: -2.2, -0.5); -1.0 (95% CI: -2.1, 0.1); 0.4 (95% CI: -0.5, 1.2), respectively]; and the reduction in anxiety scores over time was similar for all groups. A dietitian-led telehealth intervention for addictive eating in adults was more effective than a passive or control condition in reducing addictive eating scores from baseline to 6 months. Trial registration: Australia New Zealand Clinical Trial Registry ACTRN12621001079831.
MeSH term(s)	Adult ; Humans ; Australia ; Behavior, Addictive ; Anxiety/therapy ; Anxiety/psychology ; Anxiety Disorders ; Telemedicine
Language	English
Publishing date	2024-01-11
Publishing country	England
Document type	Randomized Controlled Trial ; Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1461347-5
ISSN	1095-8304 ; 0195-6663
ISSN (online)	1095-8304
ISSN	0195-6663
DOI	10.1016/j.appet.2024.107211
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Article ; Online: Genetic influences on circulating retinol and its relationship to human health.

Reay, William R / Kiltschewskij, Dylan J / Di Biase, Maria A / Gerring, Zachary F / Kundu, Kousik / Surendran, Praveen / Greco, Laura A / Clarke, Erin D / Collins, Clare E / Mondul, Alison M / Albanes, Demetrius / Cairns, Murray J

Nature communications

2024 Volume 15, Issue 1, Page(s) 1490

Abstract: Retinol is a fat-soluble vitamin that plays an essential role in many biological processes throughout the human lifespan. Here, we perform the largest genome-wide association study (GWAS) of retinol to date in up to 22,274 participants. We identify eight ...

Abstract	Retinol is a fat-soluble vitamin that plays an essential role in many biological processes throughout the human lifespan. Here, we perform the largest genome-wide association study (GWAS) of retinol to date in up to 22,274 participants. We identify eight common variant loci associated with retinol, as well as a rare-variant signal. An integrative gene prioritisation pipeline supports novel retinol-associated genes outside of the main retinol transport complex (RBP4:TTR) related to lipid biology, energy homoeostasis, and endocrine signalling. Genetic proxies of circulating retinol were then used to estimate causal relationships with almost 20,000 clinical phenotypes via a phenome-wide Mendelian randomisation study (MR-pheWAS). The MR-pheWAS suggests that retinol may exert causal effects on inflammation, adiposity, ocular measures, the microbiome, and MRI-derived brain phenotypes, amongst several others. Conversely, circulating retinol may be causally influenced by factors including lipids and serum creatinine. Finally, we demonstrate how a retinol polygenic score could identify individuals more likely to fall outside of the normative range of circulating retinol for a given age. In summary, this study provides a comprehensive evaluation of the genetics of circulating retinol, as well as revealing traits which should be prioritised for further investigation with respect to retinol related therapies or nutritional intervention.
MeSH term(s)	Humans ; Vitamin A ; Genome-Wide Association Study ; Phenotype ; Obesity ; Adiposity ; Mendelian Randomization Analysis/methods ; Retinol-Binding Proteins, Plasma
Chemical Substances	Vitamin A (11103-57-4) ; RBP4 protein, human ; Retinol-Binding Proteins, Plasma
Language	English
Publishing date	2024-02-19
Publishing country	England
Document type	Journal Article
ZDB-ID	2553671-0
ISSN	2041-1723 ; 2041-1723
ISSN (online)	2041-1723
ISSN	2041-1723
DOI	10.1038/s41467-024-45779-x
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Primary and secondary cardiovascular disease prevention interventions targeting lifestyle risk factors in women: A systematic review and meta-analysis.

Slater, Kaylee / Colyvas, Kim / Taylor, Rachael / Collins, Clare E / Hutchesson, Melinda

Frontiers in cardiovascular medicine

2022 Volume 9, Page(s) 1010528

Abstract: ... achieved statistically significant reductions in BMI at ≤ 6 months (0.95 kg/m: Conclusions: Lifestyle ...

Abstract	Background and aims: Over seven million women die from cardiovascular disease (CVD) annually. While lifestyle modification is recommended for CVD prevention, there are no systematic reviews evaluating the effectiveness of interventions targeted to women. The primary aim of this systematic review is to determine the efficacy of primary and secondary CVD prevention interventions targeting lifestyle risk factors in women. Methods: Six electronic databases were searched up to January 2022. Eligible studies included randomized controlled trials of primary or secondary CVD prevention interventions targeting CVD lifestyle risk factors (diet, physical activity, sedentary behavior, smoking, alcohol, sleep, and weight management) in women (≥18 years) that reported CVD risk markers or lifestyle risk factors. Meta-analyses were conducted on CVD risk markers and body mass index (BMI), and the level of evidence was applied to the GRADE (Grading of Recommendations Assessment, Development and Evaluation) criteria and reported. Results: Thirty-five RCTs were included (24 primary and 11 secondary prevention). Meta-analyses demonstrated that lifestyle CVD prevention interventions achieved statistically significant reductions in BMI at ≤ 6 months (0.95 kg/m Conclusions: Lifestyle interventions are important for the prevention of CVD in women, specifically to reduce systolic blood pressure in the short term (≤ 6 months) and BMI long term (>12 months). Systematic review registration: https://osf.io/bkwqm, identifier: osf-registrations-bkwqm-v1.
Language	English
Publishing date	2022-11-09
Publishing country	Switzerland
Document type	Systematic Review
ZDB-ID	2781496-8
ISSN	2297-055X
ISSN	2297-055X
DOI	10.3389/fcvm.2022.1010528
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