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  1. Article ; Online: Response to the letter by Dr Sébastien Champion regarding the study "Can mortality due to circulatory failure in comatose out-of-hospital cardiac arrest patients be predicted on admission? A study in a retrospective derivation cohort validated in a prospective cohort".

    Voicu, Sebastian

    Journal of critical care

    2016  Volume 36, Page(s) 300

    Language English
    Publishing date 2016-12
    Publishing country United States
    Document type Letter
    ZDB-ID 632818-0
    ISSN 1557-8615 ; 0883-9441
    ISSN (online) 1557-8615
    ISSN 0883-9441
    DOI 10.1016/j.jcrc.2016.07.006
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    Zs.A 2152: Show issues Location:
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  2. Article ; Online: Targeted Temperature Management for Cardiac Arrest.

    Deye, Nicolas / Voicu, Sebastian / Megarbane, Bruno

    The New England journal of medicine

    2020  Volume 382, Issue 26, Page(s) e109

    MeSH term(s) Heart Arrest ; Humans ; Hypothermia, Induced
    Language English
    Publishing date 2020-06-22
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 207154-x
    ISSN 1533-4406 ; 0028-4793
    ISSN (online) 1533-4406
    ISSN 0028-4793
    DOI 10.1056/NEJMc2011066
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: New Trend in Toxicological Screening Using Volumetric Absorptive Microsampling (VAMS) and High-Resolution Mass Spectrometry (HR/MS) Combination.

    Houzé, Pascal / Borowski, Ilona / Bito, Eugénie / Magny, Romain / Morcos, Athina / Voicu, Sebastian / Mégarbane, Bruno / Labat, Laurence

    Molecules (Basel, Switzerland)

    2023  Volume 28, Issue 8

    Abstract: In toxicology, screenings are routinely performed using chromatographic methods coupled to detection systems such as high-resolution mass spectrometry (HR/MS). The increase in specificity and sensitivity of HRMS is responsible for the development of ... ...

    Abstract In toxicology, screenings are routinely performed using chromatographic methods coupled to detection systems such as high-resolution mass spectrometry (HR/MS). The increase in specificity and sensitivity of HRMS is responsible for the development of methods for alternative samples such as Volumetric Adsorptive Micro-Sampling. Whole blood overloaded with 90 drugs was sampled with 20 µL Mitra
    MeSH term(s) Humans ; Child ; Tandem Mass Spectrometry/methods ; Blood Specimen Collection/methods ; Specimen Handling/methods ; Chromatography, Liquid/methods ; Plasma ; Dried Blood Spot Testing/methods
    Language English
    Publishing date 2023-04-14
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1413402-0
    ISSN 1420-3049 ; 1431-5165 ; 1420-3049
    ISSN (online) 1420-3049
    ISSN 1431-5165 ; 1420-3049
    DOI 10.3390/molecules28083466
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    Zs.MO 81: Show issues

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  4. Article ; Online: Topical Capsaicin To Treat Cannabinoid Hyperemesis Syndrome: Mind The Dose.

    Mégarbane, Bruno / Malissin, Isabelle / Deye, Nicolas / Voicu, Sebastian

    Clinical toxicology (Philadelphia, Pa.)

    2019  Volume 58, Issue 8, Page(s) 855–856

    Language English
    Publishing date 2019-11-25
    Publishing country England
    Document type Letter
    ZDB-ID 204476-6
    ISSN 1556-9519 ; 0009-9309 ; 0731-3810 ; 1556-3650
    ISSN (online) 1556-9519
    ISSN 0009-9309 ; 0731-3810 ; 1556-3650
    DOI 10.1080/15563650.2019.1694683
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    Zs.B 419: Show issues Location:
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  5. Article ; Online: Extracorporeal life support in cardiotoxicant poisoning-A narrative review.

    Voicu, Sebastian / M'Rad, Aymen / Malissin, Isabelle / Deye, Nicolas / Mégarbane, Bruno

    Basic & clinical pharmacology & toxicology

    2022  Volume 132, Issue 1, Page(s) 5–20

    Abstract: Extracorporeal life support (ECLS) improves circulation in life-threatening cardiac dysfunction or arrest patients. Its benefits in drug-induced cardiovascular complications are debated. Indications and outcomes are poorly established. We performed a ... ...

    Abstract Extracorporeal life support (ECLS) improves circulation in life-threatening cardiac dysfunction or arrest patients. Its benefits in drug-induced cardiovascular complications are debated. Indications and outcomes are poorly established. We performed a narrative review discussing ECLS indications, timing and results in cardiotoxicant-poisoned patients. The review was focused on antiarrhythmic drugs and aluminium phosphide. Literature analysis was limited to the past 30 years in adults. Most reports were single cases and retrospective except one prospective case series of limited size, two of them controlled. ECLS indications and timing were at the discretion of physicians in charge but mostly included persistent cardiovascular failure despite elevated doses of inotropic/vasopressor support associated with elevated blood lactate concentrations (usually, >5 mmol/L) and collapsed left ventricular ejection fraction (LVEF; usually, ≤40%). Survival improved using ECLS versus standard care in one study. Survival was ~80% if ECLS was implemented in refractory cardiovascular failure and 25%-66% if implemented in cardiac arrest. In two controlled studies, survival of ECLS-treated aluminium phosphide-poisoned patients was improved versus standard care, if implemented in the presence of systolic blood pressure ≤80 mmHg despite inotropic/vasopressor treatment, arterial pH ≤ 7.0 and LVEF ≤ 40%. Despite low-to-moderate level of evidence, ECLS seems effective to improve survival in selected cardiotoxicant-poisoned patients. Selection criteria need clarification.
    Language English
    Publishing date 2022-10-17
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2134679-3
    ISSN 1742-7843 ; 1742-7835
    ISSN (online) 1742-7843
    ISSN 1742-7835
    DOI 10.1111/bcpt.13804
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  6. Article ; Online: The presence of Pneumocystis jirovecii in critically ill patients with COVID-19.

    Alanio, Alexandre / Dellière, Sarah / Voicu, Sebastian / Bretagne, Stéphane / Mégarbane, Bruno

    The Journal of infection

    2020  Volume 82, Issue 4, Page(s) 84–123

    MeSH term(s) COVID-19 ; Coinfection ; Critical Illness ; Humans ; Pneumocystis carinii ; Pneumonia, Pneumocystis/diagnosis ; Pneumonia, Pneumocystis/epidemiology ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-11-04
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 424417-5
    ISSN 1532-2742 ; 0163-4453
    ISSN (online) 1532-2742
    ISSN 0163-4453
    DOI 10.1016/j.jinf.2020.10.034
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    Zs.A 1501: Show issues Location:
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    Zs.MG 48: Show issues

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  7. Article ; Online: Cerebral hemodynamic effects of head-up CPR in a porcine model.

    Jaeger, Deborah / Kosmopoulos, Marinos / Voicu, Sebastian / Kalra, Rajat / Gaisendrees, Christopher / Schlartenberger, Georg / Bartos, Jason A / Yannopoulos, Demetri

    Resuscitation

    2023  Volume 193, Page(s) 110039

    Abstract: Aim: To assess the hemodynamic effects of head elevation on cerebral perfusion during cardiopulmonary resuscitation (CPR) in a porcine model of cardiac arrest.: Methods: VF was induced in eight 65 kg pigs that were treated with CPR after five minutes ...

    Abstract Aim: To assess the hemodynamic effects of head elevation on cerebral perfusion during cardiopulmonary resuscitation (CPR) in a porcine model of cardiac arrest.
    Methods: VF was induced in eight 65 kg pigs that were treated with CPR after five minutes of no flow. Mean arterial pressure (MAP) was measured at the descending thoracic aorta. Internal carotid artery blood flow (CBF) was measured with an ultrasound probe. Cerebral perfusion pressure (CerPP) was calculated in two ways (CerPP
    Results: MAP and coronary perfusion pressure measurements were similar in both CPR positions (p = 0.36 and p = 0.1, respectively). ICP was significantly lower in the HUP CPR group (14.7 ± 1 mm Hg vs 26.9 ± 1 mm Hg, p < 0.001) as was ICAP (30.1 ± 2 mm Hg vs 42.6 ± 1 mmHg, p < 0.001). The proportional decrease in ICP and ICAP resulted in similar CerPP
    Conclusion: HUP did not affect cerebral perfusion pressure and it significantly decreased internal carotid blood flow.
    MeSH term(s) Animals ; Swine ; Cardiopulmonary Resuscitation/methods ; Heart Arrest/therapy ; Hemodynamics/physiology ; Arterial Pressure ; Cerebrovascular Circulation/physiology
    Language English
    Publishing date 2023-11-05
    Publishing country Ireland
    Document type Journal Article
    ZDB-ID 189901-6
    ISSN 1873-1570 ; 0300-9572
    ISSN (online) 1873-1570
    ISSN 0300-9572
    DOI 10.1016/j.resuscitation.2023.110039
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    Zs.A 1048: Show issues Location:
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  8. Article ; Online: Does COVID-19 alter the oxyhemoglobin dissociation curve? - An observational cohort study using a mixed-effect modelling.

    Laredo, Mikael / Curis, Emmanuel / Masson-Fron, Elisabeth / Voicu, Sebastian / Mégarbane, Bruno

    Clinical chemistry and laboratory medicine

    2021  Volume 59, Issue 11, Page(s) e416–e419

    MeSH term(s) Aged ; COVID-19/metabolism ; Cohort Studies ; Coronavirus Infections/complications ; Female ; Hemoglobins/metabolism ; Humans ; Hypoxia/complications ; Male ; Middle Aged ; Oxygen/blood ; Oxygen/metabolism ; Oxyhemoglobins/metabolism ; SARS-CoV-2/metabolism ; Solubility
    Chemical Substances Hemoglobins ; Oxyhemoglobins ; Oxygen (S88TT14065)
    Language English
    Publishing date 2021-06-21
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1418007-8
    ISSN 1437-4331 ; 1434-6621 ; 1437-8523
    ISSN (online) 1437-4331
    ISSN 1434-6621 ; 1437-8523
    DOI 10.1515/cclm-2021-0387
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    Zs.A 121: Show issues Location:
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  9. Conference proceedings ; Online: Microdoping of Layers for High Efficiency Silicon Heterojunction Solar Cells

    Voicu Vulcanean, Ioan / Seif, Johannes / Pingel, Sebastian / Koc, Ibrahim / Bivour, Martin / Steinmetz, Anamaria

    2023  

    Abstract: 020051-001 ... 020051-005 ... Within this paper two approaches have been attempted to improve the interfaces of silicon heterojunction devices, either intrinsic amorphous silicon a-Si:H(i) to doped layer a-Si:H(n) or a-Si:H(i) layer to silicon oxide and ... ...

    Abstract 020051-001

    020051-005

    Within this paper two approaches have been attempted to improve the interfaces of silicon heterojunction devices, either intrinsic amorphous silicon a-Si:H(i) to doped layer a-Si:H(n) or a-Si:H(i) layer to silicon oxide and nanocrystalline layer nc-Si:H (n or p). For the conventional a-Si:H based device, microdoping was implemented in the i2 layer of the a-Si:H(i) layer stack, aiming to increase the fill factor. An improvement in fill factor of up to 0.5%abs. was shown by introducing microdoping into a fraction of the i2 layer, resulting in an improved efficiency reaching 23.4% compared to the undoped reference at 23.2%. For "next generation" SHJ devices based on nc-Si:H, microdoping was implemented in the interfacial silicon oxide layer. For nc-Si:H(n) the fill factor showed a gain of up to 0.3%abs. compared with the undoped group, with the best cell reaching 22.9% efficiency. When introducing microdoping in the silicon oxide layer for nc-Si:H(p), a similar trend is observed as an increase in FF of ~0.3%abs. compared with undoped group drives the efficiency for the best cell at 23%. The two microdoping approaches decreased the series resistance, positively affecting the fill factor.
    Keywords Silicon heterojunction solar cell ; a-Si ; Nanocrystalline ; Microdoping ; Fill factor
    Subject code 621
    Language English
    Publishing country de
    Document type Conference proceedings ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: Reply letter to: Targeted temperature management using the "Esophageal Cooling Device" after cardiac arrest (the COOL study): A feasibility and safety study.

    Goury, Antoine / Voicu, Sebastian / Deye, Nicolas

    Resuscitation

    2018  Volume 123, Page(s) e7–e8

    MeSH term(s) Body Temperature ; Cold Temperature ; Heart Arrest ; Humans ; Hypothermia, Induced
    Language English
    Publishing date 2018
    Publishing country Ireland
    Document type Letter ; Comment
    ZDB-ID 189901-6
    ISSN 1873-1570 ; 0300-9572
    ISSN (online) 1873-1570
    ISSN 0300-9572
    DOI 10.1016/j.resuscitation.2017.12.001
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