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  1. Article ; Online: High Proportion of Asymptomatic SARS-CoV-2 Infections in 9 Long-Term Care Facilities, Pasadena, California, USA, April 2020.

    Feaster, Matt / Goh, Ying-Ying

    Emerging infectious diseases

    2020  Volume 26, Issue 10, Page(s) 2416–2419

    Abstract: Our analysis of coronavirus disease prevalence in 9 long-term care facilities demonstrated a high proportion (40.7%) of asymptomatic infections among residents and staff members. Infection control measures in congregate settings should include mass ... ...

    Abstract Our analysis of coronavirus disease prevalence in 9 long-term care facilities demonstrated a high proportion (40.7%) of asymptomatic infections among residents and staff members. Infection control measures in congregate settings should include mass testing-based strategies in concert with symptom screening for greater effectiveness in preventing the spread of severe acute respiratory syndrome coronavirus 2.
    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; Assisted Living Facilities/statistics & numerical data ; Asymptomatic Infections/epidemiology ; COVID-19 ; California/epidemiology ; Cities/epidemiology ; Coronavirus Infections/complications ; Coronavirus Infections/diagnosis ; Coronavirus Infections/epidemiology ; Female ; Health Personnel/statistics & numerical data ; Housekeeping/statistics & numerical data ; Humans ; Maintenance/statistics & numerical data ; Male ; Middle Aged ; Pandemics ; Pneumonia, Viral/complications ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/epidemiology ; Prevalence ; Skilled Nursing Facilities/statistics & numerical data
    Keywords covid19
    Language English
    Publishing date 2020-07-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1380686-5
    ISSN 1080-6059 ; 1080-6040
    ISSN (online) 1080-6059
    ISSN 1080-6040
    DOI 10.3201/eid2610.202694
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: High Proportion of Asymptomatic SARS-CoV-2 Infections in 9 Long-Term Care Facilities, Pasadena, California, USA, April 2020

    Matt Feaster / Ying-Ying Goh

    Emerging Infectious Diseases, Vol 26, Iss 10, Pp 2416-

    2020  Volume 2419

    Abstract: Our analysis of coronavirus disease prevalence in 9 long-term care facilities demonstrated a high proportion (40.7%) of asymptomatic infections among residents and staff members. Infection control measures in congregate settings should include mass ... ...

    Abstract Our analysis of coronavirus disease prevalence in 9 long-term care facilities demonstrated a high proportion (40.7%) of asymptomatic infections among residents and staff members. Infection control measures in congregate settings should include mass testing–based strategies in concert with symptom screening for greater effectiveness in preventing the spread of severe acute respiratory syndrome coronavirus 2.
    Keywords COVID-19 ; skilled nursing facility ; assisted living facility ; long-term care facility ; 2019 novel coronavirus disease ; severe acute respiratory syndrome coronavirus 2 ; Medicine ; R ; Infectious and parasitic diseases ; RC109-216 ; covid19
    Language English
    Publishing date 2020-10-01T00:00:00Z
    Publisher Centers for Disease Control and Prevention
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article: High Proportion of Asymptomatic SARS-CoV-2 Infections in 9 Long-Term Care Facilities, Pasadena, California, USA, April 2020

    Feaster, Matt / Goh, Ying-Ying

    Emerg Infect Dis

    Abstract: Our analysis of coronavirus disease prevalence in 9 long-term care facilities demonstrated a high proportion (40.7%) of asymptomatic infections among residents and staff members. Infection control measures in congregate settings should include mass ... ...

    Abstract Our analysis of coronavirus disease prevalence in 9 long-term care facilities demonstrated a high proportion (40.7%) of asymptomatic infections among residents and staff members. Infection control measures in congregate settings should include mass testing-based strategies in concert with symptom screening for greater effectiveness in preventing the spread of severe acute respiratory syndrome coronavirus 2.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #624970
    Database COVID19

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  4. Article ; Online: Job strain associated with increases in ambulatory blood and pulse pressure during and after work hours among female hotel room cleaners.

    Feaster, Matt / Krause, Niklas

    American journal of industrial medicine

    2018  Volume 61, Issue 6, Page(s) 492–503

    Abstract: Background: Previously documented elevated hypertension rates among Las Vegas hotel room cleaners are hypothesized to be associated with job strain.: Methods: Job strain was assessed by questionnaire. Ambulatory blood pressure (ABP) was recorded ... ...

    Abstract Background: Previously documented elevated hypertension rates among Las Vegas hotel room cleaners are hypothesized to be associated with job strain.
    Methods: Job strain was assessed by questionnaire. Ambulatory blood pressure (ABP) was recorded among 419 female cleaners from five hotels during 18 waking hours. Multiple linear regression models assessed associations of job strain with ABP and pulse pressure for 18-h, work hours, and after work hours.
    Results: Higher job strain was associated with increased 18-h systolic ABP, after work hours systolic ABP, and ambulatory pulse pressure. Dependents at home but not social support at work attenuated effects. Among hypertensive workers, job strain effects were partially buffered by anti-hypertensive medication.
    Conclusions: High job strain is positively associated with blood pressure among female hotel workers suggesting potential for primary prevention at work. Work organizational changes, stress management, and active ABP surveillance and hypertension management should be considered for integrated intervention programs.
    MeSH term(s) Adult ; Antihypertensive Agents ; Blood Pressure/physiology ; Blood Pressure Monitoring, Ambulatory/methods ; Female ; Housekeeping ; Humans ; Hypertension/drug therapy ; Hypertension/epidemiology ; Hypertension/etiology ; Linear Models ; Middle Aged ; Nevada/epidemiology ; Occupational Stress/complications ; Occupational Stress/epidemiology ; Risk Factors ; Surveys and Questionnaires ; Young Adult
    Chemical Substances Antihypertensive Agents
    Language English
    Publishing date 2018-03-22
    Publishing country United States
    Document type Comparative Study ; Journal Article ; Research Support, U.S. Gov't, P.H.S.
    ZDB-ID 604538-8
    ISSN 1097-0274 ; 0271-3586
    ISSN (online) 1097-0274
    ISSN 0271-3586
    DOI 10.1002/ajim.22837
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Index cases first identified by nasal-swab rapid COVID-19 tests had more transmission to household contacts than cases identified by other test types.

    Ji, Jenny / Viloria Winnett, Alexander / Shelby, Natasha / Reyes, Jessica A / Schlenker, Noah W / Davich, Hannah / Caldera, Saharai / Tognazzini, Colten / Goh, Ying-Ying / Feaster, Matt / Ismagilov, Rustem F

    PloS one

    2023  Volume 18, Issue 10, Page(s) e0292389

    Abstract: At-home rapid COVID-19 tests in the U.S. utilize nasal-swab specimens and require high viral loads to reliably give positive results. Longitudinal studies from the onset of infection have found infectious virus can present in oral specimens days before ... ...

    Abstract At-home rapid COVID-19 tests in the U.S. utilize nasal-swab specimens and require high viral loads to reliably give positive results. Longitudinal studies from the onset of infection have found infectious virus can present in oral specimens days before nasal. Detection and initiation of infection-control practices may therefore be delayed when nasal-swab rapid tests are used, resulting in greater transmission to contacts. We assessed whether index cases first identified by rapid nasal-swab COVID-19 tests had more transmission to household contacts than index cases who used other test types (tests with higher analytical sensitivity and/or non-nasal specimen types). In this observational cohort study, 370 individuals from 85 households with a recent COVID-19 case were screened at least daily by RT-qPCR on one or more self-collected upper-respiratory specimen types. A two-level random intercept model was used to assess the association between the infection outcome of household contacts and each covariable (household size, race/ethnicity, age, vaccination status, viral variant, infection-control practices, and whether a rapid nasal-swab test was used to initially identify the household index case). Transmission was quantified by adjusted secondary attack rates (aSAR) and adjusted odds ratios (aOR). An aSAR of 53.6% (95% CI 38.8-68.3%) was observed among households where the index case first tested positive by a rapid nasal-swab COVID-19 test, which was significantly higher than the aSAR for households where the index case utilized another test type (27.2% 95% CI 19.5-35.0%, P = 0.003 pairwise comparisons of predictive margins). We observed an aOR of 4.90 (95% CI 1.65-14.56) for transmission to household contacts when a nasal-swab rapid test was used to identify the index case, compared to other test types. Use of nasal-swab rapid COVID-19 tests for initial detection of infection and initiation of infection control may be less effective at limiting transmission to household contacts than other test types.
    MeSH term(s) Humans ; COVID-19/diagnosis ; COVID-19/epidemiology ; SARS-CoV-2 ; Family Characteristics ; Cohort Studies ; Nose
    Language English
    Publishing date 2023-10-05
    Publishing country United States
    Document type Observational Study ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0292389
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Extreme differences in SARS-CoV-2 viral loads among respiratory specimen types during presumed pre-infectious and infectious periods.

    Viloria Winnett, Alexander / Akana, Reid / Shelby, Natasha / Davich, Hannah / Caldera, Saharai / Yamada, Taikun / Reyna, John Raymond B / Romano, Anna E / Carter, Alyssa M / Kim, Mi Kyung / Thomson, Matt / Tognazzini, Colten / Feaster, Matthew / Goh, Ying-Ying / Chew, Yap Ching / Ismagilov, Rustem F

    PNAS nexus

    2023  Volume 2, Issue 3, Page(s) pgad033

    Abstract: SARS-CoV-2 viral-load measurements from a single-specimen type are used to establish diagnostic strategies, interpret clinical-trial results for vaccines and therapeutics, model viral transmission, and understand virus-host interactions. However, ... ...

    Abstract SARS-CoV-2 viral-load measurements from a single-specimen type are used to establish diagnostic strategies, interpret clinical-trial results for vaccines and therapeutics, model viral transmission, and understand virus-host interactions. However, measurements from a single-specimen type are implicitly assumed to be representative of other specimen types. We quantified viral-load timecourses from individuals who began daily self-sampling of saliva, anterior-nares (nasal), and oropharyngeal (throat) swabs before or at the incidence of infection with the Omicron variant. Viral loads in different specimen types from the same person at the same timepoint exhibited extreme differences, up to 10
    Language English
    Publishing date 2023-03-14
    Publishing country England
    Document type Journal Article
    ISSN 2752-6542
    ISSN (online) 2752-6542
    DOI 10.1093/pnasnexus/pgad033
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: The Influence of Housing Status on the HIV Continuum of Care: Results From a Multisite Study of Patient Navigation Models to Build a Medical Home for People Living With HIV Experiencing Homelessness.

    Rajabiun, Serena / Tryon, Janell / Feaster, Matt / Pan, Amy / McKeithan, Lisa / Fortu, Karen / Cabral, Howard J / Borne, Deborah / Altice, Frederick L

    American journal of public health

    2020  Volume 108, Issue S7, Page(s) S539–S545

    Abstract: Objectives. ...

    Abstract Objectives.
    Language English
    Publishing date 2020-09-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 121100-6
    ISSN 1541-0048 ; 0090-0036 ; 0002-9572
    ISSN (online) 1541-0048
    ISSN 0090-0036 ; 0002-9572
    DOI 10.2105/AJPH.2018.304736
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Index cases first identified by nasal-swab rapid COVID-19 tests had more transmission to household contacts than cases identified by other test types.

    Jenny Ji / Alexander Viloria Winnett / Natasha Shelby / Jessica A Reyes / Noah W Schlenker / Hannah Davich / Saharai Caldera / Colten Tognazzini / Ying-Ying Goh / Matt Feaster / Rustem F Ismagilov

    PLoS ONE, Vol 18, Iss 10, p e

    2023  Volume 0292389

    Abstract: At-home rapid COVID-19 tests in the U.S. utilize nasal-swab specimens and require high viral loads to reliably give positive results. Longitudinal studies from the onset of infection have found infectious virus can present in oral specimens days before ... ...

    Abstract At-home rapid COVID-19 tests in the U.S. utilize nasal-swab specimens and require high viral loads to reliably give positive results. Longitudinal studies from the onset of infection have found infectious virus can present in oral specimens days before nasal. Detection and initiation of infection-control practices may therefore be delayed when nasal-swab rapid tests are used, resulting in greater transmission to contacts. We assessed whether index cases first identified by rapid nasal-swab COVID-19 tests had more transmission to household contacts than index cases who used other test types (tests with higher analytical sensitivity and/or non-nasal specimen types). In this observational cohort study, 370 individuals from 85 households with a recent COVID-19 case were screened at least daily by RT-qPCR on one or more self-collected upper-respiratory specimen types. A two-level random intercept model was used to assess the association between the infection outcome of household contacts and each covariable (household size, race/ethnicity, age, vaccination status, viral variant, infection-control practices, and whether a rapid nasal-swab test was used to initially identify the household index case). Transmission was quantified by adjusted secondary attack rates (aSAR) and adjusted odds ratios (aOR). An aSAR of 53.6% (95% CI 38.8-68.3%) was observed among households where the index case first tested positive by a rapid nasal-swab COVID-19 test, which was significantly higher than the aSAR for households where the index case utilized another test type (27.2% 95% CI 19.5-35.0%, P = 0.003 pairwise comparisons of predictive margins). We observed an aOR of 4.90 (95% CI 1.65-14.56) for transmission to household contacts when a nasal-swab rapid test was used to identify the index case, compared to other test types. Use of nasal-swab rapid COVID-19 tests for initial detection of infection and initiation of infection control may be less effective at limiting transmission to household contacts than other test types.
    Keywords Medicine ; R ; Science ; Q
    Subject code 150
    Language English
    Publishing date 2023-01-01T00:00:00Z
    Publisher Public Library of Science (PLoS)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Daily SARS-CoV-2 Nasal Antigen Tests Miss Infected and Presumably Infectious People Due to Viral Load Differences among Specimen Types.

    Viloria Winnett, Alexander / Akana, Reid / Shelby, Natasha / Davich, Hannah / Caldera, Saharai / Yamada, Taikun / Reyna, John Raymond B / Romano, Anna E / Carter, Alyssa M / Kim, Mi Kyung / Thomson, Matt / Tognazzini, Colten / Feaster, Matthew / Goh, Ying-Ying / Chew, Yap Ching / Ismagilov, Rustem F

    Microbiology spectrum

    2023  Volume 11, Issue 4, Page(s) e0129523

    Abstract: In a recent household transmission study of SARS-CoV-2, we found extreme differences in SARS-CoV-2 viral loads among paired saliva, anterior nares swab (ANS), and oropharyngeal swab specimens collected from the same time point. We hypothesized these ... ...

    Abstract In a recent household transmission study of SARS-CoV-2, we found extreme differences in SARS-CoV-2 viral loads among paired saliva, anterior nares swab (ANS), and oropharyngeal swab specimens collected from the same time point. We hypothesized these differences may hinder low-analytical-sensitivity assays (including antigen rapid diagnostic tests [Ag-RDTs]) by using a single specimen type (e.g., ANS) from reliably detecting infected and infectious individuals. We evaluated daily at-home ANS Ag-RDTs (Quidel QuickVue) in a cross-sectional analysis of 228 individuals and a longitudinal analysis (throughout infection) of 17 individuals enrolled early in the course of infection. Ag-RDT results were compared to reverse transcription-quantitative PCR (RT-qPCR) results and high, presumably infectious viral loads (in each, or any, specimen type). The ANS Ag-RDT correctly detected only 44% of time points from infected individuals on cross-sectional analysis, and this population had an inferred limit of detection of 7.6 × 10
    MeSH term(s) Humans ; Cross-Sectional Studies ; Longitudinal Studies ; SARS-CoV-2 ; Viral Load ; COVID-19/diagnosis
    Language English
    Publishing date 2023-06-14
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2807133-5
    ISSN 2165-0497 ; 2165-0497
    ISSN (online) 2165-0497
    ISSN 2165-0497
    DOI 10.1128/spectrum.01295-23
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Surveillance of Flea-Borne Typhus in California, 2011-2019.

    Yomogida, Kyle / Kjemtrup, Anne / Martínez-López, Beatriz / Ibrahim, Mireille / Contreras, Zuelma / Ngo, Van / Halai, Umme-Aiman / Balter, Sharon / Feaster, Matt / Zahn, Matthew / Shearer, Eric / Sorvillo, Rochelle / Balanji, Nora / Torres, Cindy / Prado, Belinda / Porse, Charsey / Kramer, Vicki

    The American journal of tropical medicine and hygiene

    2023  Volume 110, Issue 1, Page(s) 142–149

    Abstract: Flea-borne typhus (FBT), also referred to as murine typhus, is an acute febrile disease in humans caused by the bacteria Rickettsia typhi. Currently, cases of FBT are reported for public health surveillance purposes (i.e., to detect incidence and ... ...

    Abstract Flea-borne typhus (FBT), also referred to as murine typhus, is an acute febrile disease in humans caused by the bacteria Rickettsia typhi. Currently, cases of FBT are reported for public health surveillance purposes (i.e., to detect incidence and outbreaks) in a few U.S. states. In California, healthcare providers and testing laboratories are mandated to report to their respective local public health jurisdictions whenever R. typhi or antibodies reactive to R. typhi are detected in a patient, who then report cases to state health department. In this study, we characterize the epidemiology of flea-borne typhus cases in California from 2011 to 2019. A total of 881 cases were reported during this period, with most cases reported among residents of Los Angeles and Orange Counties (97%). Demographics, animal exposures, and clinical courses for case patients were summarized. Additionally, spatiotemporal cluster analyses pointed to five areas in southern California with persistent FBT transmission.
    MeSH term(s) Animals ; Mice ; Humans ; Typhus, Endemic Flea-Borne/diagnosis ; Typhus, Epidemic Louse-Borne ; Rickettsia typhi ; California/epidemiology ; Siphonaptera/microbiology
    Language English
    Publishing date 2023-12-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2942-7
    ISSN 1476-1645 ; 0002-9637
    ISSN (online) 1476-1645
    ISSN 0002-9637
    DOI 10.4269/ajtmh.23-0272
    Database MEDical Literature Analysis and Retrieval System OnLINE

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