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  1. Article ; Online: Hospitalisation due to acute cardiovascular conditions: is screening for recreational drug use justified?

    Choudry, Fizzah A / Jones, Daniel A / Archbold, R Andrew

    Heart (British Cardiac Society)

    2023  Volume 109, Issue 21, Page(s) 1582–1583

    Language English
    Publishing date 2023-10-12
    Publishing country England
    Document type Editorial
    ZDB-ID 1303417-0
    ISSN 1468-201X ; 1355-6037
    ISSN (online) 1468-201X
    ISSN 1355-6037
    DOI 10.1136/heartjnl-2023-322808
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    Ui IV Zs.40: Show issues Location:
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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 112: Show issues

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  2. Article ; Online: Editorial commentary: Understanding thrombosis in COVID-19 - A long way to go.

    Choudry, Fizzah A / Mathur, Anthony / Jones, Daniel A

    Trends in cardiovascular medicine

    2020  Volume 31, Issue 3, Page(s) 161–162

    MeSH term(s) COVID-19 ; Humans ; SARS-CoV-2 ; Thrombosis/epidemiology
    Language English
    Publishing date 2020-12-28
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 1097434-9
    ISSN 1873-2615 ; 1050-1738
    ISSN (online) 1873-2615
    ISSN 1050-1738
    DOI 10.1016/j.tcm.2020.12.006
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    Zs.A 3419: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  3. Article ; Online: Long-Term Outcomes of COVID-19-Associated ST-Elevation Myocardial Infarction Treated With Primary PCI.

    Choudry, Fizzah A / Rathod, Krishnaraj S / Baumbach, Andreas / Mathur, Anthony / Jones, Daniel A

    Cardiovascular revascularization medicine : including molecular interventions

    2022  Volume 43, Page(s) 133–135

    MeSH term(s) COVID-19 ; Coronary Angiography ; Humans ; Myocardial Infarction/therapy ; Percutaneous Coronary Intervention/adverse effects ; ST Elevation Myocardial Infarction/diagnostic imaging ; ST Elevation Myocardial Infarction/therapy ; Treatment Outcome
    Language English
    Publishing date 2022-05-25
    Publishing country United States
    Document type Letter
    ZDB-ID 2212113-4
    ISSN 1878-0938 ; 1553-8389
    ISSN (online) 1878-0938
    ISSN 1553-8389
    DOI 10.1016/j.carrev.2022.05.029
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    Zs.A 5562: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article ; Online: Reply: Pitfalls of Unfractionated Heparin Use During ST-Segment Elevation Myocardial Infarction in Patients With COVID-19 Infection.

    Choudry, Fizzah A / Rathod, Krishnaraj S / Baumbach, Andreas / Mathur, Anthony / Jones, Daniel A

    Journal of the American College of Cardiology

    2021  Volume 77, Issue 1, Page(s) 105–106

    MeSH term(s) COVID-19 ; Heparin/adverse effects ; Hirudins ; Humans ; SARS-CoV-2 ; ST Elevation Myocardial Infarction/diagnosis
    Chemical Substances Hirudins ; Heparin (9005-49-6)
    Language English
    Publishing date 2021-01-08
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 605507-2
    ISSN 1558-3597 ; 0735-1097
    ISSN (online) 1558-3597
    ISSN 0735-1097
    DOI 10.1016/j.jacc.2020.11.004
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    Zs.A 1846: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 196: Show issues

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  5. Article ; Online: Intravascular ultrasound-guided management of ST-elevation myocardial infarction in a patient with lung cancer and myocardial metastasis.

    Ramasamy, Anantharaman / Bajaj, Retesh / Choudry, Fizzah A / Pugliese, Francesca / Baumbach, Andreas / Bourantas, Christos V

    European heart journal

    2020  Volume 41, Issue 33, Page(s) 3201

    MeSH term(s) Coronary Angiography ; Humans ; Lung Neoplasms/diagnostic imaging ; Lung Neoplasms/therapy ; Percutaneous Coronary Intervention ; ST Elevation Myocardial Infarction/diagnostic imaging ; ST Elevation Myocardial Infarction/therapy ; Treatment Outcome ; Ultrasonography, Interventional
    Language English
    Publishing date 2020-03-27
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 603098-1
    ISSN 1522-9645 ; 0195-668X
    ISSN (online) 1522-9645
    ISSN 0195-668X
    DOI 10.1093/eurheartj/ehaa004
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    Zs.A 1563: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 640: Show issues

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  6. Article ; Online: Thrombus Embolisation: Prevention is Better than Cure.

    Choudry, Fizzah A / Weerackody, Roshan P / Jones, Daniel A / Mathur, Anthony

    Interventional cardiology (London, England)

    2019  Volume 14, Issue 2, Page(s) 95–101

    Abstract: Thrombus embolisation complicating primary percutaneous coronary intervention in ST-elevation myocardial infarction is associated with an increase in adverse outcomes. However, there are currently no proven recommendations for intervention in the setting ...

    Abstract Thrombus embolisation complicating primary percutaneous coronary intervention in ST-elevation myocardial infarction is associated with an increase in adverse outcomes. However, there are currently no proven recommendations for intervention in the setting of large thrombus burden. In this review, we discuss the clinical implications of thrombus embolisation and angiographic predictors of embolisation, and provide an update of current evidence for some preventative strategies, both pharmacological and mechanical, in this setting.
    Keywords covid19
    Language English
    Publishing date 2019-05-21
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2813989-6
    ISSN 1756-1485 ; 1756-1477
    ISSN (online) 1756-1485
    ISSN 1756-1477
    DOI 10.15420/icr.2019.11
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  7. Article: The safety of deferred coronary angiography in COVID-19 patients with acute coronary syndrome: the Barts COVID recovered pathway.

    Teoh, Zhi / Rathod, Krishnaraj S / Comer, Katrina / Tyrlis, Angelos / Choudry, Fizzah A / Ozkor, Mick / Archbold, R Andrew / Guttmann, Oliver / Wragg, Andrew / Baumbach, Andreas / Jain, Ajay K / Mathur, Anthony / Jones, Daniel A

    American journal of cardiovascular disease

    2023  Volume 13, Issue 3, Page(s) 168–176

    Abstract: Objective: To assess the safety and effectiveness of a novel pathway of deferrred invasive angiography in low-risk NSTEMI patients with concurrent COVID-19 infections; contrary to current UK guidelines recommending invasive coronary angiography in ... ...

    Abstract Objective: To assess the safety and effectiveness of a novel pathway of deferrred invasive angiography in low-risk NSTEMI patients with concurrent COVID-19 infections; contrary to current UK guidelines recommending invasive coronary angiography in NSTEMI patients within 72 hours.
    Methods: This was a single-centre, observational study of all NSTEMI patients referred for inpatient coronary angiography at Barts Heart Centre, between March 2020 and June 2022. Demographic, procedural and outcome data were collected as part of a national cardiac audit.
    Results: 201 COVID positive NSTEMI patients were referred for angiography at Barts Heart Centre. 10 patients died from COVID related respiratory complications prior to angiography. Therefore, 191 patients underwent deferred angiography (median time 16 days from COVID diagnosis). The median GRACE score was 128 (IQR 86-153). Troponin levels were significantly elevated on initial COVID diagnosis compared to time of their procedure. 73% patients had a culprit lesion identified. 61.2% receiving PCI. Patients were followed-up for a median of 363 days (IQR 120-485 days) with MACE rates of 7.3%. This is comparable to the MACE event for NSTEMI patients (n=4529) without COVID at our institution treated during the same time-period (8.1%).
    Conclusion: This study demonstrates the safety and effectiveness of deferred coronary angiography on a COVID-Recovered pathway after a period of medical management for patients presenting with NSTEMI and concurrent COVID-19 infection. There was no adverse signal associated with the wait for angiography with similar MACE rates to the non-deferred NSTEMI cohort without COVID-19.
    Language English
    Publishing date 2023-06-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2616844-3
    ISSN 2160-200X
    ISSN 2160-200X
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  8. Article ; Online: Thrombus Burden and Outcomes in Patients With COVID-19 Presenting With STEMI Across the Pandemic.

    Rathod, Krishnaraj S / Teoh, Zhi / Tyrlis, Angelos / Choudry, Fizzah A / Hamshere, Stephen M / Comer, Katrina / Guttmann, Oliver / Jain, Ajay K / Ozkor, Muhiddin A / Wragg, Andrew / Archbold, R Andrew / Baumbach, Andreas / Mathur, Anthony / Jones, Daniel A

    Journal of the American College of Cardiology

    2023  Volume 81, Issue 25, Page(s) 2406–2416

    Abstract: Background: It has been previously reported during the first COVID-19 outbreak that patients presenting with ST-segment elevation myocardial infarction (STEMI) and concurrent COVID-19 infection have increased thrombus burden and poorer outcomes. To date, ...

    Abstract Background: It has been previously reported during the first COVID-19 outbreak that patients presenting with ST-segment elevation myocardial infarction (STEMI) and concurrent COVID-19 infection have increased thrombus burden and poorer outcomes. To date, there have been no reports comparing the outcomes of COVID-19-positive STEMI patients across all waves of the pandemic.
    Objectives: This study compared the baseline demographic, procedural, and angiographic characteristics alongside the clinical outcomes of patients presenting with STEMI and concurrent COVID-19 infection across the COVID-19 pandemic in the United Kingdom.
    Methods: This was a single-center, observational study of 1,269 consecutive patients admitted with confirmed STEMI treated with percutaneous coronary intervention (between January 3, 2020 and October 3, 2022). COVID-19-positive patients were split into 3 groups based upon the time course of the pandemic, and a comparison was made between waves.
    Results: A total of 154 COVID-19-positive patients with STEMI were included in the present analysis and were compared with 1,115 COVID-19-negative patients. Early during the pandemic (wave 1), STEMI patients presenting with concurrent COVID-19 infection had high rates of cardiac arrest, evidence of increased thrombus burden, bigger infarcts, and worse outcomes. However, by wave 3, no differences existed in outcomes between COVID-19-positive and -negative patients, with significant differences compared with earlier COVID-19-positive patients. Poor outcomes later in the study period were predominantly in unvaccinated individuals.
    Conclusions: Significant changes have occurred in the clinical characteristics, angiographic features, and outcomes of STEMI patients with COVID-19 infection treated by primary percutaneous coronary intervention during the course of the pandemic. Importantly, outcomes of recent waves and in vaccinated individuals are no different to a non-COVID-19 population.
    MeSH term(s) Humans ; COVID-19/epidemiology ; ST Elevation Myocardial Infarction/diagnosis ; ST Elevation Myocardial Infarction/epidemiology ; ST Elevation Myocardial Infarction/therapy ; Pandemics ; Thrombosis/diagnostic imaging ; Thrombosis/epidemiology ; Thrombosis/etiology ; United Kingdom/epidemiology ; Percutaneous Coronary Intervention/adverse effects ; Treatment Outcome
    Language English
    Publishing date 2023-06-21
    Publishing country United States
    Document type Observational Study ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 605507-2
    ISSN 1558-3597 ; 0735-1097
    ISSN (online) 1558-3597
    ISSN 0735-1097
    DOI 10.1016/j.jacc.2023.04.029
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1846: Show issues Location:
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    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 196: Show issues

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  9. Article: An exploration of the early discharge approach for low-risk STEMI patients following primary percutaneous coronary intervention.

    Broughton, Nicole / Comer, Katrina / Casey-Gillman, Oliver / Moore, Lizze / Antoniou, Sotiris / Patel, Riyaz / Fhadil, Sadeer / Wright, Paul / Ozkor, Muhiddin / Guttmann, Oliver / Baumbach, Andreas / Wragg, Andrew / Jain, Ajay J / Choudry, Fizzah / Mathur, Anthony / Rathod, Krishnaraj S / Jones, Daniel A

    American journal of cardiovascular disease

    2023  Volume 13, Issue 2, Page(s) 32–42

    Abstract: Recently, there has been growing interest in the early discharge strategy for low-risk patients who have undergone primary percutaneous coronary intervention (PCI) to treat ST-segment elevation myocardial infarction (STEMI). So far findings have ... ...

    Abstract Recently, there has been growing interest in the early discharge strategy for low-risk patients who have undergone primary percutaneous coronary intervention (PCI) to treat ST-segment elevation myocardial infarction (STEMI). So far findings have suggested there are multiple advantages of shorter hospital stays, including that it could be a safe way to be more cost- and resource-efficient, reduce cases of hospital-acquired infection and boost patient satisfaction. However, there are remaining concerns surrounding safety, patient education, adequate follow-up and the generalisability of the findings from current studies which are mostly small-scale. By assessing the current research, we describe the advantages, disadvantages and challenges of early hospital discharge for STEMI and discuss the factors that determine if a patient can be considered low risk. If it is feasible to safely employ a strategy like this, the implications for healthcare systems worldwide could be extremely beneficial, particularly in lower-income economies and when we consider the detrimental impacts of the recent COVID-19 pandemic on healthcare systems.
    Language English
    Publishing date 2023-04-15
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2616844-3
    ISSN 2160-200X
    ISSN 2160-200X
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  10. Article ; Online: Five-year follow-up of intracoronary autologous cell therapy in acute myocardial infarction: the REGENERATE-AMI trial.

    Mathur, Anthony / Sim, Doo Sun / Choudry, Fizzah / Veerapen, Jessry / Colicchia, Martina / Turlejski, Tymoteusz / Hussain, Mohsin / Hamshere, Stephen / Locca, Didier / Rakhit, Roby / Crake, Tom / Kastrup, Jens / Agrawal, Samir / Jones, Daniel A / Martin, John

    ESC heart failure

    2022  Volume 9, Issue 2, Page(s) 1152–1159

    Abstract: Aims: The long-term outcomes of the intracoronary delivery of autologous bone marrow-derived cells (BMCs) after acute myocardial infarction are not well established. Following the promising 1 year results of the REGENERATE-AMI trial (despite it not ... ...

    Abstract Aims: The long-term outcomes of the intracoronary delivery of autologous bone marrow-derived cells (BMCs) after acute myocardial infarction are not well established. Following the promising 1 year results of the REGENERATE-AMI trial (despite it not achieving its primary endpoint), this paper presents the analysis of the 5 year clinical outcomes of these acute myocardial infarction patients who were treated with an early intracoronary autologous BMC infusion or placebo.
    Methods and results: A 5 year follow-up of major adverse cardiac events (defined as the composite of all-cause death, recurrent myocardial infarction, and all coronary revascularization) and of rehospitalization for heart failure was completed in 85 patients (BMC n = 46 and placebo n = 39). The incidence of major adverse cardiac events was similar between the BMC-treated patients and the placebo group (26.1% vs. 18.0%, P = 0.41). There were no cases of cardiac death in either group, but an increase in non-cardiac death was seen in the BMC group (6.5% vs. 0%, P = 0.11). The rates of recurrent myocardial infarction and repeat revascularization were similar between the two groups. There were no cases of rehospitalization for heart failure in either group.
    Conclusion: This 5 year follow-up analysis of the REGENERATE-AMI trial did not show an improvement in clinical outcomes for patients treated with cell therapy. This contrasts with the 1 year results which showed improvements in the surrogate outcome measures of ejection fraction and myocardial salvage index.
    MeSH term(s) Bone Marrow Transplantation/methods ; Follow-Up Studies ; Humans ; Myocardial Infarction/therapy ; Transplantation, Autologous ; Treatment Outcome
    Language English
    Publishing date 2022-01-18
    Publishing country England
    Document type Journal Article ; Randomized Controlled Trial ; Research Support, Non-U.S. Gov't
    ZDB-ID 2814355-3
    ISSN 2055-5822 ; 2055-5822
    ISSN (online) 2055-5822
    ISSN 2055-5822
    DOI 10.1002/ehf2.13786
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