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  1. Book ; Online ; E-Book: New insights on antiviral probiotics

    Al-Kassaa, Imad

    from research to applications

    2017  

    Author's details Imad Al Kassaa
    Keywords Probiotics ; Antiviral Agents ; Virus Diseases / therapy
    Language English
    Size 1 Online-Ressource (xii, 119 Seiten), Illustrationen
    Publisher Springer
    Publishing place Cham
    Publishing country Switzerland
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT019501817
    ISBN 978-3-319-49688-7 ; 9783319496870 ; 3-319-49688-3 ; 3319496875
    DOI 10.1007/978-3-319-49688-7
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: Occurrence and risk factors of feline immunodeficiency virus (FIV) and feline leukaemia virus (FeLV) in cats of Lebanon.

    Khalife, Sara / Kassaa, Imad Al

    Comparative immunology, microbiology and infectious diseases

    2022  Volume 93, Page(s) 101931

    Abstract: A cross-sectional study was carried out between April 2020 and August 2021. Blood samples were collected from 260 household cats recruited in different clinics in North and Mount Lebanon, with the aim of determining the seroprevalence of feline ... ...

    Abstract A cross-sectional study was carried out between April 2020 and August 2021. Blood samples were collected from 260 household cats recruited in different clinics in North and Mount Lebanon, with the aim of determining the seroprevalence of feline immunodeficiency virus (FIV) and feline leukaemia virus (FeLV). The seroprevalence reported reached 18.84% (95% CI 0.14-0.24) and 13.84% (95% CI 0.09-0.18) for FIV and FeLV, respectively. FIV seropositivity was associated with a younger age, health and neuter status, lymphoma, lethargy, and vomiting. Furthermore, male sex, neuter status, lymphoma, anaemia, lethargy, and vomiting were significantly associated with FeLV seropositivity. This first data from Lebanon emphasizes the need for implementing preventive programmes to cope with FIV- and FeLV-associated morbidity and mortality among cats.
    MeSH term(s) Cats ; Male ; Animals ; Immunodeficiency Virus, Feline ; Leukemia Virus, Feline ; Seroepidemiologic Studies ; Cross-Sectional Studies ; Lebanon ; Lethargy/veterinary ; Risk Factors ; Lymphoma/veterinary ; Feline Acquired Immunodeficiency Syndrome/epidemiology ; Cat Diseases/epidemiology
    Language English
    Publishing date 2022-12-17
    Publishing country England
    Document type Journal Article
    ZDB-ID 436522-7
    ISSN 1878-1667 ; 0147-9571
    ISSN (online) 1878-1667
    ISSN 0147-9571
    DOI 10.1016/j.cimid.2022.101931
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1443: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  3. Article: Editorial: Malnutrition and Infections.

    Villena, Julio / Kitazawa, Haruki / Al Kassaa, Imad / Alvarez, Susana

    Frontiers in nutrition

    2022  Volume 9, Page(s) 897780

    Language English
    Publishing date 2022-04-06
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2776676-7
    ISSN 2296-861X
    ISSN 2296-861X
    DOI 10.3389/fnut.2022.897780
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Editorial: Antimicrobial resistance and antimicrobial alternatives.

    Osman, Marwan / Al Kassaa, Imad / El Omari, Khaled / Kassem, Issmat I

    Frontiers in medicine

    2023  Volume 10, Page(s) 1171283

    Language English
    Publishing date 2023-03-06
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2775999-4
    ISSN 2296-858X
    ISSN 2296-858X
    DOI 10.3389/fmed.2023.1171283
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Editorial

    Marwan Osman / Imad Al Kassaa / Khaled El Omari / Issmat I. Kassem

    Frontiers in Medicine, Vol

    Antimicrobial resistance and antimicrobial alternatives

    2023  Volume 10

    Keywords antimicrobial resistance (AMR) ; One Health ; molecular epidemiology ; sustainability ; refugee crisis ; infection prevention and control (IPC) ; Medicine (General) ; R5-920
    Language English
    Publishing date 2023-03-01T00:00:00Z
    Publisher Frontiers Media S.A.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article: Zoonotic Tuberculosis: A Neglected Disease in the Middle East and North Africa (MENA) Region.

    Kasir, Dalal / Osman, Nour / Awik, Aicha / El Ratel, Imane / Rafei, Rayane / Al Kassaa, Imad / El Safadi, Dima / Salma, Rayane / El Omari, Khaled / Cummings, Kevin J / Kassem, Issmat I / Osman, Marwan

    Diseases (Basel, Switzerland)

    2023  Volume 11, Issue 1

    Abstract: Mycobacterium ... ...

    Abstract Mycobacterium bovis
    Language English
    Publishing date 2023-03-01
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2720869-2
    ISSN 2079-9721
    ISSN 2079-9721
    DOI 10.3390/diseases11010039
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Antiviral Probiotics: A New Concept in Medical Sciences

    AL KASSAA, Imad

    New Insights on Antiviral Probiotics

    Abstract: In recent decades, probiotics have shown beneficial effects on animal and human health. Probiotics can protect the host against several health threats, including infectious diseases. Before 1995, researchers believed that the effect of probiotics was ... ...

    Abstract In recent decades, probiotics have shown beneficial effects on animal and human health. Probiotics can protect the host against several health threats, including infectious diseases. Before 1995, researchers believed that the effect of probiotics was only on gut microbiota which can restore the gut flora and thus prevent pathogenic bacteria from triggering gastroenteritis. Recent studies have shown that the immunomodulatory activity is the most important mechanism of action of probiotics. From this information, researchers started to evaluate the effect of some immunobiotics, not only on pathogenic bacteria but also on viruses, including enteric and respiratory viruses. Several studies have confirmed the potential antiviral activity of some probiotics due to the immunomodulatory effect. These studies were conducted on humans (clinical trials) and in animal models. In this chapter, probiotics with antiviral effect against respiratory and enteric viruses will be presented and discussed, as well as their mechanisms of action.
    Keywords covid19
    Publisher PMC
    Document type Article ; Online
    DOI 10.1007/978-3-319-49688-7_1
    Database COVID19

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  8. Article ; Online: Enterococcus faecium CMUL1216 an Immunobiotic Strain with a Potential Application in Animal Sector.

    Al Kassaa, Imad / Mechmchani, Samah / Zaylaa, Mazen / Bachar Ismail, Mohamad / El Omari, Khaled / Dabboussi, Fouad / Hamze, Monzer

    Biocontrol science

    2021  Volume 26, Issue 2, Page(s) 75–84

    Abstract: Antibiotic misuse in the animal sector is the first cause of the emergence and spreading of MDR bacteria. Prevention of infectious diseases and enhancement of animal growth are the main effects of antibiotics that push farmers and veterinarians to use ... ...

    Abstract Antibiotic misuse in the animal sector is the first cause of the emergence and spreading of MDR bacteria. Prevention of infectious diseases and enhancement of animal growth are the main effects of antibiotics that push farmers and veterinarians to use this molecule in animal farms. Thus, the use of alternative solutions such as natural antimicrobial substances as well as probiotic strains is a crucial need in this sector. Enterococcus faecium CMUL1216 was isolated from healthy human baby's feces. This strain was assessed in vitro for probiotic properties including activity against many pathogens isolated from animal, human, and soil samples. CMUL1216 strain exhibits good antimicrobial activity against indicator pathogens in both planktonic and biofilm forms. In addition, CMUL1216 strain showed a strong biofilm formation. Furthermore, CMUL1216 exhibits a good anti-inflammatory effect by inducing the secretion of IL-10 in vitro. Moreover, this strain did not show any pathogenic characteristics such as hemolytic effect, presence of virulence genes as well as susceptibility to the majority of antibiotic families. E. faecium CMUL1216 could be a good candidate to be used a probiotic strain in the animal sector in order to maintain animal health and therefore reduce antibiotic resistance caused by the excessive use in this sector.
    MeSH term(s) Animals ; Anti-Bacterial Agents/pharmacology ; Drug Resistance, Microbial ; Enterococcus faecium ; Humans ; Probiotics ; Virulence
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2021-06-04
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 1414347-1
    ISSN 1884-0205 ; 1342-4815
    ISSN (online) 1884-0205
    ISSN 1342-4815
    DOI 10.4265/bio.26.75
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5121: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  9. Article ; Online: High association of COVID-19 severity with poor gut health score in Lebanese patients.

    Al Kassaa, Imad / El Omari, Sarah / Abbas, Nada / Papon, Nicolas / Drider, Djamel / Kassem, Issmat I / Osman, Marwan

    PloS one

    2021  Volume 16, Issue 10, Page(s) e0258913

    Abstract: Background: Coronavirus disease 2019 (COVID-19) has affected millions of lives globally. However, the disease has presented more extreme challenges for developing countries that are experiencing economic crises. Studies on COVID-19 symptoms and gut ... ...

    Abstract Background: Coronavirus disease 2019 (COVID-19) has affected millions of lives globally. However, the disease has presented more extreme challenges for developing countries that are experiencing economic crises. Studies on COVID-19 symptoms and gut health are scarce and have not fully analyzed possible associations between gut health and disease pathophysiology. Therefore, this study aimed to demonstrate a potential association between gut health and COVID-19 severity in the Lebanese community, which has been experiencing a severe economic crisis.
    Methods: This cross-sectional study investigated SARS-CoV-2 PCR-positive Lebanese patients. Participants were interviewed and gut health, COVID-19 symptoms, and different metrics were analyzed using simple and multiple logistic regression models.
    Results: Analysis of the data showed that 25% of participants were asymptomatic, while an equal proportion experienced severe symptoms, including dyspnea (22.7%), oxygen need (7.5%), and hospitalization (3.1%). The mean age of the participants was 38.3 ±0.8 years, and the majority were males (63.9%), married (68.2%), and currently employed (66.7%). A negative correlation was found between gut health score and COVID-19 symptoms (Kendall's tau-b = -0.153, P = 0.004); indicating that low gut health was associated with more severe COVID-19 cases. Additionally, participants who reported unhealthy food intake were more likely to experience severe symptoms (Kendall's tau-b = 0.118, P = 0.049). When all items were taken into consideration, multiple ordinal logistic regression models showed a significant association between COVID-19 symptoms and each of the following variables: working status, flu-like illness episodes, and gut health score. COVID-19 severe symptoms were more common among patients having poor gut health scores (OR:1.31, 95%CI:1.07-1.61; P = 0.008), experiencing more than one episode of flu-like illness per year (OR:2.85, 95%CI:1.58-5.15; P = 0.001), and owning a job (OR:2.00, 95%CI:1.1-3.65; P = 0.023).
    Conclusions: To our knowledge, this is the first study that showed the impact of gut health and exposure to respiratory viruses on COVID-19 severity in Lebanon. These findings can facilitate combating the pandemic in Lebanon.
    MeSH term(s) Adult ; COVID-19/epidemiology ; Cross-Sectional Studies ; Female ; Humans ; Intestinal Diseases/epidemiology ; Lebanon/epidemiology ; Male ; Pandemics ; SARS-CoV-2 ; Severity of Illness Index
    Language English
    Publishing date 2021-10-21
    Publishing country United States
    Document type Clinical Trial ; Journal Article
    ISSN 1932-6203
    ISSN (online) 1932-6203
    DOI 10.1371/journal.pone.0258913
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Zoonotic Tuberculosis

    Dalal Kasir / Nour Osman / Aicha Awik / Imane El Ratel / Rayane Rafei / Imad Al Kassaa / Dima El Safadi / Rayane Salma / Khaled El Omari / Kevin J. Cummings / Issmat I. Kassem / Marwan Osman

    Diseases, Vol 11, Iss 39, p

    A Neglected Disease in the Middle East and North Africa (MENA) Region

    2023  Volume 39

    Abstract: Mycobacterium bovis is the etiologic agent of bovine tuberculosis (BTB), a serious infectious disease in both humans and animals. BTB is a zoonotic disease primarily affecting cattle and occasionally humans infected through close contact with infected ... ...

    Abstract Mycobacterium bovis is the etiologic agent of bovine tuberculosis (BTB), a serious infectious disease in both humans and animals. BTB is a zoonotic disease primarily affecting cattle and occasionally humans infected through close contact with infected hosts or the consumption of unpasteurized dairy products. Zoonotic tuberculosis is strongly associated with poverty and poor hygiene, and low- and middle-income countries bear the brunt of the disease. BTB has been increasingly recognized as a growing public health threat in developing countries. However, the lack of effective surveillance programs in many of these countries poses a barrier to accurately determining the true burden of this disease. Additionally, the control of BTB is threatened by the emergence of drug-resistant strains that affect the effectiveness of current treatment regimens. Here, we analyzed current trends in the epidemiology of the disease as well as the antimicrobial susceptibility patterns of M. bovis in the Middle East and North Africa (MENA) region, a region that includes several developing countries. Following PRISMA guidelines, a total of 90 studies conducted in the MENA region were selected. Our findings revealed that the prevalence of BTB among humans and cattle varied significantly according to the population size and country in the MENA region. Most of the available studies were based on culture and/or PCR strategies and were published without including data on antimicrobial resistance and molecular typing. Our findings highlighted the paramount need for the use of appropriate diagnostic tools and the implementation of sustainable control measures, especially at the human/animal interface, in the MENA region.
    Keywords Mycobacterium bovis ; one health ; epidemiology ; antimicrobial resistance ; MENA region ; Medicine ; R
    Subject code 630
    Language English
    Publishing date 2023-03-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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