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  1. Article ; Online: The Pathology Job Market Post-COVID-19-Where Are We Now? A Comparison of Pathology Job Advertisements From 2013-2017 to 2018-2022.

    Zynger, Debra L / Pernick, Nat

    Archives of pathology & laboratory medicine

    2023  Volume 147, Issue 11, Page(s) 1227–1228

    MeSH term(s) Humans ; Advertising ; COVID-19 ; Workforce ; Employment
    Language English
    Publishing date 2023-10-23
    Publishing country United States
    Document type Letter
    ZDB-ID 194119-7
    ISSN 1543-2165 ; 0363-0153 ; 0096-8528 ; 0003-9985
    ISSN (online) 1543-2165
    ISSN 0363-0153 ; 0096-8528 ; 0003-9985
    DOI 10.5858/arpa.2023-0211-LE
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ud II Zs.36: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  2. Article: What's new in genitourinary pathology 2023: WHO 5th edition updates for urinary tract, prostate, testis, and penis.

    Choy, Bonnie / Tretiakova, Maria / Zynger, Debra L

    Journal of pathology and translational medicine

    2023  Volume 58, Issue 1, Page(s) 45–48

    Abstract: The 5th edition WHO Classification of Urinary and Male Genital Tumours (2022) introduced many significant changes relevant to urologic daily practice, mainly to renal tumors which was covered in the What's New newsletter in September 2022. In this ... ...

    Abstract The 5th edition WHO Classification of Urinary and Male Genital Tumours (2022) introduced many significant changes relevant to urologic daily practice, mainly to renal tumors which was covered in the What's New newsletter in September 2022. In this newsletter, we summarize the notable changes to bladder, prostate, testis, and penis based on the 5th edition of the WHO.
    Language English
    Publishing date 2023-12-27
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 3022395-7
    ISSN 2383-7845 ; 2383-7837
    ISSN (online) 2383-7845
    ISSN 2383-7837
    DOI 10.4132/jptm.2023.12.11
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Book: Biopsy interpretation of the kidney and adrenal gland

    Tickoo, Satish K. / Chen, Ying-Bei / Zynger, Debra L.

    (Biopsy interpretation series)

    2016  

    Author's details Satish K. Tickoo ; Ying-Bei Chen ; Debra L. Zynger
    Series title Biopsy interpretation series
    Keywords Kidney Neoplasms / diagnosis ; Adrenal Gland Neoplasms / diagnosis ; Biopsy, Needle / methods ; Kidney / physiopathology ; Adrenal Glands / physiopathology
    Language English
    Size VII, 356 S. : zahlr. Ill., graph. Darst.
    Publisher Wolters Kluwer
    Publishing place Philadelphia u.a.
    Publishing country United States
    Document type Book
    Note Includes bibliographical references and index ; Renal biopsy and normal histology -- Histologic pattern approach for differential diagnosis of renal tumors / Satish K. Tickoo -- Common types of renal cell carcinoma / Satish K. Tickoo -- Renal cell carcinoma : uncommon types / Satish K. Tickoo and Ying-bei Chen -- Benign renal epithelial tumors / Ying-bei Chen -- Renal mesenchymal and mixed mesenchymal-epithelial tumors / Ying-bei Chen -- Miscellaneous tumors and tumorlike conditions / Ying-bei Chen -- Renal pelvic tumors / Debra Zynger -- Adrenal biopsy and normal histology / Debra Zynger -- Drenal primary tumors and nontumors / Debra Zynger -- Adrenal metastases / Debra Zynger -- Pediatric renal tumors and neuroblastoma / Satish K. Tickoo -- Ancillary tests / Satish K. Tickoo, Debra Zynger, and Ying-bei Chen -- Fine needle aspiration cytology of renal and adrenal lesions / Jasreman Dhillon and Marino E. Leon
    Accompanying material Zugang zur Internetausgabe über Code
    HBZ-ID HT018786718
    ISBN 978-1-4511-7647-6 ; 1-4511-7647-3
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2015 A 3603 available for loan (reading room) Lesesaal EG
    Zugang zur Internetausgabe über Code aus lizenzrechtlichen Gründen nicht verfügbar

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  4. Article ; Online: The stratification of positive lymph nodes into pN1 and pN2 for upper urinary tract carcinoma is not prognostically significant.

    Wu, Douglas J / Wong, Megan N / Lee, Cheryl T / Zynger, Debra L

    Human pathology

    2023  Volume 137, Page(s) 48–55

    Abstract: ... The ... ...

    Abstract The 3
    MeSH term(s) Humans ; Extranodal Extension/pathology ; Lymphatic Metastasis/pathology ; Prognosis ; Carcinoma/pathology ; Urologic Neoplasms/pathology ; Lymph Nodes/surgery ; Lymph Nodes/pathology ; Urinary Tract/pathology ; Neoplasm Staging ; Lymph Node Excision ; Retrospective Studies
    Language English
    Publishing date 2023-04-23
    Publishing country United States
    Document type Journal Article
    ZDB-ID 207657-3
    ISSN 1532-8392 ; 0046-8177
    ISSN (online) 1532-8392
    ISSN 0046-8177
    DOI 10.1016/j.humpath.2023.04.010
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 722: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article ; Online: Renal Pelvic Urothelial Carcinoma With Invasion Into Renal Medulla Can Be Redefined as pT2 to Improve Correlation With Survival.

    Wong, Megan N / Wu, Douglas J / Lee, Cheryl T / Zynger, Debra L

    Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc

    2023  Volume 36, Issue 6, Page(s) 100140

    Abstract: According to the American Joint Cancer Committee, pT3 renal pelvic carcinoma is defined as tumor invading the renal parenchyma and/or peripelvic fat and is the largest pT category, with notable survival heterogeneity. Anatomical landmarks within the ... ...

    Abstract According to the American Joint Cancer Committee, pT3 renal pelvic carcinoma is defined as tumor invading the renal parenchyma and/or peripelvic fat and is the largest pT category, with notable survival heterogeneity. Anatomical landmarks within the renal pelvis can be difficult to discern. Using glomeruli as a boundary to differentiate renal medulla invasion from renal cortex invasion, this study aimed to compare patient survival of pT3 renal pelvic urothelial carcinoma on the basis of the extent of renal parenchyma invasion and, thereafter, determine whether redefining pT2 and pT3 improves pT correlation with survival. Cases with primary renal pelvic urothelial carcinoma were identified through a review of pathology reports from nephroureterectomies completed at our institution from 2010 to 2019 (n = 145). Tumors were stratified by pT, pN, lymphovascular invasion, and invasion of the renal medulla versus invasion of the renal cortex and/or peripelvic fat. Overall survival between groups was compared using Kaplan-Meier survival models and Cox regression multivariate analysis. pT2 and pT3 tumors had similar 5-year overall survival, with multivariate analysis demonstrating an overlap between hazard ratios (HRs) for pT2 (HR, 2.20; 95% CI, 0.70-6.95) and pT3 (HR, 3.15; 95% CI, 1.63-6.09). pT3 tumors with peripelvic fat and/or renal cortex invasion had a 3.25-fold worse prognosis than pT3 tumors with renal medulla invasion alone. Furthermore, pT2 and pT3 tumors with only renal medulla invasion had similar overall survival, whereas pT3 tumors with peripelvic fat and/or renal cortex invasion had a worse prognosis (P = .00036). Reclassifying pT3 tumors with only renal medulla invasion as pT2 yielded greater separation between survival curves and HR. Thus, we recommend redefining pT2 renal pelvic carcinoma to include renal medulla invasion and restricting pT3 to peripelvic fat and/or renal cortex invasion to improve the prognostic accuracy of pT classification.
    MeSH term(s) Humans ; Carcinoma, Transitional Cell/pathology ; Neoplasm Staging ; Urinary Bladder Neoplasms/pathology ; Neoplasm Invasiveness/pathology ; Kidney Neoplasms/pathology ; Prognosis ; Retrospective Studies
    Language English
    Publishing date 2023-02-20
    Publishing country United States
    Document type Review ; Journal Article
    ZDB-ID 645073-8
    ISSN 1530-0285 ; 0893-3952
    ISSN (online) 1530-0285
    ISSN 0893-3952
    DOI 10.1016/j.modpat.2023.100140
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2450: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  6. Article: Implementation of a required 3rd-year medical student surgical pathology clinical experience.

    Wegman, Sonya J / Tretter, Jason G / Zynger, Debra L

    Academic pathology

    2022  Volume 9, Issue 1, Page(s) 100027

    Abstract: Few medical schools have required experience ​in surgical pathology during the clinical years. After introducing a pilot and preliminary surgical pathology clinical experience into the curriculum, we initiated a required 3rd-year medical student surgical ...

    Abstract Few medical schools have required experience ​in surgical pathology during the clinical years. After introducing a pilot and preliminary surgical pathology clinical experience into the curriculum, we initiated a required 3rd-year medical student surgical pathology clinical experience that consisted of a one hour introductory lecture; one hour gross room, histology, and immunohistochemistry laboratory introduction; and one hour of one-on-one case sign-out preceptorship with a subspecialty surgical pathologist within the surgery and obstetrics/gynecology block. Concepts that were covered included specimen processing, intraoperative frozen section consultation, completing specimen requisitions, interpreting synoptic reports, and pTNM staging. Students evaluated the surgical pathologist from 1 to 5 (1 "poor/unhelpful," 2 "marginal," 3 "neutral," 4 "good," 5 "excellent/useful"). Ten multiple-choice questions (included as part of a perioperative services exam) and attendance were incorporated into students' perioperative services rotation grade. From 2014 to 2018, 757 students participated in the required 3rd-year surgical pathology clinical experience. Thirty academic subspecialty pathologists acted as preceptors with an average of nine sessions per preceptor per year. Evaluation data from 316 students from 2015 to 2018 showed a mean preceptor rating of 4.8/5 (range 4.0-5.0). Students scored an average of 81% on the surgical pathology portion of the exam (range 21-99% for each question). We successfully implemented a required medical student surgical pathology clinical experience. At the clerkship's conclusion, students demonstrated understanding of key concepts and rated their preceptorship experience highly.
    Language English
    Publishing date 2022-03-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2819382-9
    ISSN 2374-2895
    ISSN 2374-2895
    DOI 10.1016/j.acpath.2022.100027
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Clinicopathologic features of scrotal leiomyosarcoma: single institutional experience of ten cases.

    Taylor, Anne T / Dason, Shawn / Zynger, Debra L

    Human pathology

    2022  Volume 124, Page(s) 96–102

    Abstract: Scrotal leiomyosarcoma arises from the subcutaneous smooth muscle layer and is an exceptionally rare disease process, with only six patients in the largest reported case series. This rarity creates uncertainties regarding diagnosis, surgical management, ... ...

    Abstract Scrotal leiomyosarcoma arises from the subcutaneous smooth muscle layer and is an exceptionally rare disease process, with only six patients in the largest reported case series. This rarity creates uncertainties regarding diagnosis, surgical management, and clinical outcomes. Our purpose was to retrospectively describe our institutional experience with scrotal leiomyosarcoma from 2010 to 2022. Slides were reviewed with case inclusion requiring both nuclear atypia and mitotic activity. Ten patients with scrotal leiomyosarcoma were identified. Clinical impression included scrotal cyst in nine cases. The median age at diagnosis was 52 years (range: 29-75 years). The mean tumor size was 1.6 cm (range: 0.4-3.7 cm). Margins were positive in three cases and close in one case, prompting four re-excisions. The mean mitotic rate was 2.3 per 10 high-power field (range: 1-11), with mean Ki67 of 4.6% (range: 1-15%). Nine of the tumors were grade 1, while 1 was grade 2. Four patients had disease-specific follow-up. The remaining six patients have not had disease-specific surveillance. None of the ten patients have shown evidence of recurrence (median follow-up: 75 months, range: 0-116 months). Our series demonstrates that scrotal leiomyosarcoma has a deceptive clinical presentation with a wide age range and small tumor size. With complete surgical resection, scrotal leiomyosarcoma has an excellent prognosis and rigorous follow-up or adjuvant treatment is not likely to be necessary. Cases with unusual clinical or pathologic findings, such as large tumor size or high mitotic rate, may merit more intensive disease-specific surveillance.
    MeSH term(s) Humans ; Leiomyosarcoma/diagnosis ; Leiomyosarcoma/surgery ; Male ; Prognosis ; Retrospective Studies ; Scrotum/pathology ; Scrotum/surgery ; Skin Neoplasms
    Language English
    Publishing date 2022-04-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 207657-3
    ISSN 1532-8392 ; 0046-8177
    ISSN (online) 1532-8392
    ISSN 0046-8177
    DOI 10.1016/j.humpath.2022.03.011
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 722: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  8. Article ; Online: Reclassifying pT3 renal pelvic urothelial carcinoma with renal parenchyma invasion to pT2 improves correlation with overall survival.

    Wu, Douglas / Lee, Cheryl T / Zynger, Debra L

    Human pathology

    2022  Volume 125, Page(s) 79–86

    Abstract: The American Joint Cancer Committee pT categorization in renal pelvic carcinoma defines pT3 as invasion of renal parenchyma, invasion of peripelvic fat, or both. However, survival heterogeneity within the pT3 category has been demonstrated. This ... ...

    Abstract The American Joint Cancer Committee pT categorization in renal pelvic carcinoma defines pT3 as invasion of renal parenchyma, invasion of peripelvic fat, or both. However, survival heterogeneity within the pT3 category has been demonstrated. This investigation sought to compare survival between pT categories of renal pelvic urothelial carcinoma and identify modifications to improve correlation with survival. Pathology reports from nephroureterectomies performed at our institution from 2010 to 2019 were analyzed to identify primary renal pelvic urothelial carcinoma (n = 146). Tumors were stratified based on pT, pN, and invasion of renal parenchyma vs invasion of peripelvic fat with or without renal parenchyma invasion. Kaplan-Meier survival curves and Cox regression multivariate analysis were used to compare overall survival between groups. Similar survival curves were observed for pT2 and pT3 tumors. Multivariate analysis confirmed overlapping hazard ratios (HRs) for pT2 (HR = 2.64, 95% confidence interval [CI] = 0.69, 10.06) and pT3 (HR = 4.42, 95% CI = 2.08, 9.37). pT3 tumors with peripelvic fat invasion, regardless of renal parenchyma involvement, had a 3.3-fold worse overall survival than pT3 tumors with only renal parenchyma involvement. Additionally, pT3 tumors with only renal parenchyma invasion had similar survival compared to pT2, while pT3 tumors with peripelvic fat invasion had worse overall survival (p = 0.00091). Reclassifying renal parenchyma invasion as pT2 yielded greater survival curve separation and greater difference in HRs. For renal pelvic urothelial carcinoma, modifying the pT3 category to only include tumors with peripelvic fat invasion and expanding the pT2 category to include renal parenchyma invasion may improve pT correlation with overall survival.
    MeSH term(s) Carcinoma, Transitional Cell/pathology ; Humans ; Kidney Neoplasms/pathology ; Neoplasm Staging ; Prognosis ; Retrospective Studies ; Urinary Bladder Neoplasms/pathology
    Language English
    Publishing date 2022-03-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 207657-3
    ISSN 1532-8392 ; 0046-8177
    ISSN (online) 1532-8392
    ISSN 0046-8177
    DOI 10.1016/j.humpath.2022.03.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 722: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  9. Article ; Online: Understanding the Pathology Job Market: An Analysis of 2330 Pathology Job Advertisements From 2013 Through 2017.

    Zynger, Debra L / Pernick, Nat

    Archives of pathology & laboratory medicine

    2019  Volume 143, Issue 1, Page(s) 9–10

    MeSH term(s) Advertising as Topic ; Humans ; Internship and Residency ; Pathologists ; Surveys and Questionnaires ; United States ; Universities
    Language English
    Publishing date 2019-02-19
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 194119-7
    ISSN 1543-2165 ; 0363-0153 ; 0096-8528 ; 0003-9985
    ISSN (online) 1543-2165
    ISSN 0363-0153 ; 0096-8528 ; 0003-9985
    DOI 10.5858/arpa.2018-0388-LE
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ud II Zs.36: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  10. Article ; Online: HER2 loss after neoadjuvant treatment: is the adjuvant trastuzumab treatment feasible?-reply.

    Xian, Zhaoying / Zynger, Debra L

    Human pathology

    2017  Volume 65, Page(s) 247–248

    Language English
    Publishing date 2017-07
    Publishing country United States
    Document type Letter
    ZDB-ID 207657-3
    ISSN 1532-8392 ; 0046-8177
    ISSN (online) 1532-8392
    ISSN 0046-8177
    DOI 10.1016/j.humpath.2017.02.026
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 722: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

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