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  1. Article ; Conference proceedings: Seltene Neoplasie der Glandula parotidea

    Dandachi, Amer / Seuthe Inga, M. C. / Eichhorn, Sabine / Park, Jonas

    Laryngo-Rhino-Otologie

    2024  Volume 103, Issue S 02

    Event/congress 95. Jahresversammlung Deutsche Gesellschaft für Hals-Nasen-Ohren-Heilkunde, Kopf- und Hals-Chirurgie e. V., Bonn, Messe Essen, 2024-05-08
    Language German
    Publishing date 2024-04-19
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article ; Conference proceedings
    ZDB-ID 96005-6
    ISSN 1438-8685 ; 0935-8943 ; 0340-1588
    ISSN (online) 1438-8685
    ISSN 0935-8943 ; 0340-1588
    DOI 10.1055/s-0044-1783997
    Database Thieme publisher's database

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    In stock of ZB MED Cologne/Königswinter

    Ul II Zs.95: Show issues Location:
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  2. Article ; Conference proceedings: Rare Neoplasm of the Parotid Gland

    Dandachi, Amer / Seuthe, Inga M.C. / Eichhorn, Sabine / Park, Jonas

    Laryngo-Rhino-Otologie

    2024  Volume 103, Issue S 02

    Event/congress 95th Annual Meeting German Society of Oto-Rhino-Laryngology, Head and Neck Surgery e. V., Bonn, Messe Essen, 2024-05-08
    Language English
    Publishing date 2024-04-19
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article ; Conference proceedings
    ZDB-ID 96005-6
    ISSN 1438-8685 ; 0935-8943 ; 0340-1588
    ISSN (online) 1438-8685
    ISSN 0935-8943 ; 0340-1588
    DOI 10.1055/s-0044-1784547
    Database Thieme publisher's database

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    In stock of ZB MED Cologne/Königswinter

    Ul II Zs.95: Show issues Location:
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  3. Conference proceedings: Veränderungen von Angst und Depression während der palliativen und kurativen Therapie von Kopf-Hals-Tumor-Patienten: Eine Analyse anhand des HADS-Fragebogens

    Motamedi, Golnaz / Hermann, Manuel / Eichhorn, Sabine / Seuthe, Inga / Park, Jonas

    2024  , Page(s) 50

    Event/congress Jahrestagung der Vereinigung Westdeutscher Hals-Nasen-Ohren-Ärzte; Köln; Vereinigung Westdeutscher HNO-Ärzte; 2024
    Keywords Medizin, Gesundheit
    Publishing date 2024-02-09
    Publisher German Medical Science GMS Publishing House; Düsseldorf
    Document type Conference proceedings
    DOI 10.3205/24wdhno50
    Database German Medical Science

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  4. Article ; Online: German coasts harbor non-O1/non-O139 Vibrio cholerae with clinical virulence gene profiles.

    Zhang, Quantao / Alter, Thomas / Strauch, Eckhard / Eichhorn, Inga / Borowiak, Maria / Deneke, Carlus / Fleischmann, Susanne

    Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases

    2024  Volume 120, Page(s) 105587

    Abstract: Non-O1/non-O139 Vibrio cholerae (NOVC) are ubiquitous in aquatic ecosystems. In rare cases, they can cause intestinal and extra-intestinal infections in human. This ability is associated with various virulence factors. The presence of NOVC in German ... ...

    Abstract Non-O1/non-O139 Vibrio cholerae (NOVC) are ubiquitous in aquatic ecosystems. In rare cases, they can cause intestinal and extra-intestinal infections in human. This ability is associated with various virulence factors. The presence of NOVC in German North Sea and Baltic Sea was observed in previous studies. However, data on virulence characteristics are still scarce. Therefore, this work aimed to investigating the virulence potential of NOVC isolated in these two regions. In total, 31 NOVC strains were collected and subjected to whole genome sequencing. In silico analysis of the pathogenic potential was performed based on the detection of genes involved in colonization and virulence. Phenotypic assays, including biofilm formation, mobility and human serum resistance assays were applied for validation. Associated toxin genes (hlyA, rtxA, chxA and stn), pathogenicity islands (Vibrio pathogenicity island 2 (VPI-II) and Vibrio seventh pathogenicity island 2 (VSP-II)) and secretion systems (Type II, III and VI secretion system) were observed. A maximum likelihood analysis from shared core genes revealed a close relationship between clinical NOVCs published in NCBI and environmental strains from this study. NOVC strains are more mobile at 37 °C than at 25 °C, and 68% of the NOVC strains could form strong biofilms at both temperatures. All tested strains were able to lyse erythrocytes from both human and sheep blood. Additionally, one strain could survive up to 60% and seven strains up to 40% human serum at 37 °C. Overall, the genetic virulence profile as well as the phenotypic virulence characteristics of the investigated NOVC from the German North Sea and Baltic Sea suggest potential human pathogenicity.
    MeSH term(s) Virulence Factors/genetics ; Humans ; Virulence/genetics ; Vibrio cholerae non-O1/genetics ; Vibrio cholerae non-O1/pathogenicity ; Vibrio cholerae non-O1/isolation & purification ; Germany ; Genomic Islands/genetics ; Biofilms/growth & development ; Phylogeny ; North Sea ; Vibrio cholerae/genetics ; Vibrio cholerae/pathogenicity ; Vibrio cholerae/classification ; Cholera/microbiology ; Animals ; Whole Genome Sequencing
    Chemical Substances Virulence Factors
    Language English
    Publishing date 2024-03-20
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2037068-4
    ISSN 1567-7257 ; 1567-1348
    ISSN (online) 1567-7257
    ISSN 1567-1348
    DOI 10.1016/j.meegid.2024.105587
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Conference proceedings: Durchführbarkeit zentraler Hörtestungen bei Patienten mit Demenz

    Alyoussef, Wael / Eichhorn, Sabine / Streitenberg, Lada / Seuthe, Inga M. C. / Park, Jonas J.-H.

    2024  , Page(s) 7

    Event/congress Jahrestagung der Vereinigung Westdeutscher Hals-Nasen-Ohren-Ärzte; Köln; Vereinigung Westdeutscher HNO-Ärzte; 2024
    Keywords Medizin, Gesundheit
    Publishing date 2024-02-09
    Publisher German Medical Science GMS Publishing House; Düsseldorf
    Document type Conference proceedings
    DOI 10.3205/24wdhno07
    Database German Medical Science

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  6. Conference proceedings: Nebenwirkungen und ihr Management in Abhängigkeit von den Komorbiditäten bei HNO-ärztlich durchgeführter medikamentöser Tumortherapie im Rahmen der Radiochemotherapie bei Kopf-Hals-Tumorpatienten

    Eichhorn, Sabine / Seuthe, Inga / Erdogan, Eren / Veleva, Tina / Park, Jonas J.-H.

    2024  , Page(s) 16

    Event/congress Jahrestagung der Vereinigung Westdeutscher Hals-Nasen-Ohren-Ärzte; Köln; Vereinigung Westdeutscher HNO-Ärzte; 2024
    Keywords Medizin, Gesundheit
    Publishing date 2024-02-09
    Publisher German Medical Science GMS Publishing House; Düsseldorf
    Document type Conference proceedings
    DOI 10.3205/24wdhno16
    Database German Medical Science

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  7. Article ; Conference proceedings: Machbarkeit und Therapiesicherheit der HNO-ärztlich geführten Durchführung der kurativen medikamentösen Tumortherapie (MT) bei multimorbiden Kopf-Hals-Tumorpatienten (KHT)

    Eichhorn, Sabine / Seuthe, Inga M.C. / Erdogan, Eren / Veleva, Tina / Park, Jonas

    Laryngo-Rhino-Otologie

    2024  Volume 103, Issue S 02

    Event/congress 95. Jahresversammlung Deutsche Gesellschaft für Hals-Nasen-Ohren-Heilkunde, Kopf- und Hals-Chirurgie e. V., Bonn, Messe Essen, 2024-05-08
    Language German
    Publishing date 2024-04-19
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article ; Conference proceedings
    ZDB-ID 96005-6
    ISSN 1438-8685 ; 0935-8943 ; 0340-1588
    ISSN (online) 1438-8685
    ISSN 0935-8943 ; 0340-1588
    DOI 10.1055/s-0044-1784073
    Database Thieme publisher's database

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    In stock of ZB MED Cologne/Königswinter

    Ul II Zs.95: Show issues Location:
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  8. Article ; Conference proceedings: Feasibility and therapeutic safety of ENT-led implementation of curative drug tumor therapy (DTT) in multimorbid head and neck cancer patients (HNC)

    Eichhorn, Sabine / Seuthe, Inga M.C. / Erdogan, Eren / Veleva, Tina / Park, Jonas

    Laryngo-Rhino-Otologie

    2024  Volume 103, Issue S 02

    Event/congress 95th Annual Meeting German Society of Oto-Rhino-Laryngology, Head and Neck Surgery e. V., Bonn, Messe Essen, 2024-05-08
    Language English
    Publishing date 2024-04-19
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article ; Conference proceedings
    ZDB-ID 96005-6
    ISSN 1438-8685 ; 0935-8943 ; 0340-1588
    ISSN (online) 1438-8685
    ISSN 0935-8943 ; 0340-1588
    DOI 10.1055/s-0044-1784649
    Database Thieme publisher's database

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    In stock of ZB MED Cologne/Königswinter

    Ul II Zs.95: Show issues Location:
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  9. Article ; Conference proceedings: Veränderung von Angst und Depression anhand des HADS (Hospital Anxiety and Depression Scale)-Fragebogens während der palliativen und kurativen Therapie von Kopf-Hals-Tumor Patienten

    Heidary, Moeid / Motamedi, Golnaz / Hermann, Manuel / Eichhorn, Sabine / Seuthe, Inga M.C. / Park, Jonas

    Laryngo-Rhino-Otologie

    2024  Volume 103, Issue S 02

    Event/congress 95. Jahresversammlung Deutsche Gesellschaft für Hals-Nasen-Ohren-Heilkunde, Kopf- und Hals-Chirurgie e. V., Bonn, Messe Essen, 2024-05-08
    Language German
    Publishing date 2024-04-19
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article ; Conference proceedings
    ZDB-ID 96005-6
    ISSN 1438-8685 ; 0935-8943 ; 0340-1588
    ISSN (online) 1438-8685
    ISSN 0935-8943 ; 0340-1588
    DOI 10.1055/s-0044-1784110
    Database Thieme publisher's database

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    In stock of ZB MED Cologne/Königswinter

    Ul II Zs.95: Show issues Location:
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  10. Article ; Conference proceedings: Change in anxiety and depression using the HADS (Hospital Anxiety and Depression Scale) questionnaire during palliative and curative therapy of head and neck cancer patients

    Heidary, Moeid / Motamedi, Golnaz / Hermann, Manuel / Eichhorn, Sabine / Seuthe, Inga M.C. / Park, Jonas

    Laryngo-Rhino-Otologie

    2024  Volume 103, Issue S 02

    Event/congress 95th Annual Meeting German Society of Oto-Rhino-Laryngology, Head and Neck Surgery e. V., Bonn, Messe Essen, 2024-05-08
    Language English
    Publishing date 2024-04-19
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article ; Conference proceedings
    ZDB-ID 96005-6
    ISSN 1438-8685 ; 0935-8943 ; 0340-1588
    ISSN (online) 1438-8685
    ISSN 0935-8943 ; 0340-1588
    DOI 10.1055/s-0044-1784694
    Database Thieme publisher's database

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    In stock of ZB MED Cologne/Königswinter

    Ul II Zs.95: Show issues Location:
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