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  1. Article: The Goudge Inquiry and Forensic Pathology in Canada.

    Milroy, Christopher M

    Academic forensic pathology

    2023  Volume 13, Issue 2, Page(s) 61–72

    Abstract: Aims: This article analyses the effects of The Inquiry into Pediatric Forensic Pathology in Ontario, commonly known as the Goudge Inquiry, and its effects upon forensic pathology in Canada.: Methods: The Goudge Inquiry was a Government of Ontario ... ...

    Abstract Aims: This article analyses the effects of The Inquiry into Pediatric Forensic Pathology in Ontario, commonly known as the Goudge Inquiry, and its effects upon forensic pathology in Canada.
    Methods: The Goudge Inquiry was a Government of Ontario public inquiry that examined the delivery of pediatric forensic pathology services to the Ontario Coroner's Office and the Canadian criminal justice system. The inquiry was conducted by Mr. Justice Goudge, a court of Appeal Judge and made substantial recommendations of improving forensic pathology in a Coroner system and its role in delivering evidence to the criminal justice system. This article reviews the inquiry and discusses the effect of the inquiry on the development of forensic pathology in Canada and academic literature about the inquiry.
    Results: The Inquiry has had important effects on the role of all expert witnesses in the courts and is the most substantial examination of forensic pathology by any judicial inquiry.
    Conclusions: The Goudge Inquiry has been considered a significant success, being described as transformative.
    Language English
    Publishing date 2023-05-10
    Publishing country United States
    Document type Journal Article
    ISSN 1925-3621
    ISSN 1925-3621
    DOI 10.1177/19253621231167016
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Letter From the Editor-In-Chief.

    Milroy, Christopher M

    Academic forensic pathology

    2020  Volume 9, Issue 3-4, Page(s) vii

    Language English
    Publishing date 2020-01-31
    Publishing country United States
    Document type Editorial
    ISSN 1925-3621
    ISSN 1925-3621
    DOI 10.1177/1925362120905406
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Elephantiasis Nostra Verrucosa at Autopsy.

    Milroy, Christopher M

    Academic forensic pathology

    2020  Volume 9, Issue 3-4, Page(s) 243–249

    Language English
    Publishing date 2020-01-31
    Publishing country United States
    Document type Journal Article
    ISSN 1925-3621
    ISSN 1925-3621
    DOI 10.1177/1925362119898794
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Letter From the Editor-In-Chief.

    Milroy, Christopher M

    Academic forensic pathology

    2019  Volume 9, Issue 1-2, Page(s) vii

    Language English
    Publishing date 2019-09-06
    Publishing country United States
    Document type Editorial
    ISSN 1925-3621
    ISSN 1925-3621
    DOI 10.1177/1925362119875362
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Subnuclear renal tubular vacuoles in alcohol use disorder.

    Auld, Finn M / Parai, Jaqueline L / Milroy, Christopher M

    Journal of forensic sciences

    2023  Volume 68, Issue 5, Page(s) 1759–1767

    Abstract: Subnuclear vacuoles in the proximal renal tubules have been reported as a histologic sign of ketoacidosis. Originally described in diabetic ketoacidosis, renal vacuoles can be found in other ketogenic states such as alcoholic ketoacidosis (AKA), ... ...

    Abstract Subnuclear vacuoles in the proximal renal tubules have been reported as a histologic sign of ketoacidosis. Originally described in diabetic ketoacidosis, renal vacuoles can be found in other ketogenic states such as alcoholic ketoacidosis (AKA), starvation, and hypothermia, underpinned by deranged fatty acid metabolism. A retrospective analysis of 133 deaths associated with alcohol use disorder (AUD) examined at autopsy between 2017 and 2020 was undertaken. This study aimed to determine the prevalence of subnuclear vacuoles in deaths of those with AUD and their specificity for deaths from AKA, and to elucidate what demographic, biochemical, and pathologic findings are associated with subnuclear vacuoles. In each case, vitreous humor biochemistry including electrolytes, glucose, and beta-hydroxybutyrate (BHB) was analyzed alongside postmortem hemoglobin A1c and renal and liver histology. Renal histology was graded for the presence of vacuoles as absent (0), scanty (1), or easily identifiable (2). Liver histology was graded for steatosis and for fibrosis if Masson trichrome staining was available. Vacuoles were commonly seen in the deaths of those with AUD. They were seen in deaths due to AKA but were not specific to that cause of death. With vacuoles present, lower vitreous sodium (139 vs. 142 mmol/L; p = 0.005), higher vitreous BHB (1.50 vs. 1.39 mmol/L; p = 0.04), severe hepatic steatosis, and severe hepatic fibrosis were seen, compared with those without renal vacuoles.
    MeSH term(s) Humans ; Retrospective Studies ; Alcoholism/complications ; Vacuoles/pathology ; Epithelial Cells/pathology ; Forensic Pathology ; Ketosis/diagnosis ; Diabetic Ketoacidosis/complications ; 3-Hydroxybutyric Acid/metabolism ; Fatty Liver/pathology
    Chemical Substances 3-Hydroxybutyric Acid (TZP1275679)
    Language English
    Publishing date 2023-07-06
    Publishing country United States
    Document type Journal Article
    ZDB-ID 219216-0
    ISSN 1556-4029 ; 0022-1198
    ISSN (online) 1556-4029
    ISSN 0022-1198
    DOI 10.1111/1556-4029.15321
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  6. Article: Deaths From Alcoholic and Diabetic Ketoacidosis at Autopsy-A Comparison Study.

    Milroy, Christopher M / Lal, Anita / Parai, Jacqueline L

    Academic forensic pathology

    2023  Volume 13, Issue 2, Page(s) 73–79

    Abstract: ... 5 to 40.4 kg/m ...

    Abstract Diabetes mellitus and alcoholism are common disorders that may result in sudden death. Ketoacidosis may occur in both conditions. Diagnosis is based on history, and post-mortem findings including biochemistry and toxicology. This study compares deaths from alcoholic and diabetic ketoacidosis from two centres with large autopsy workloads. In the study period 9332 deaths were autopsies with 151 deaths diagnosed as ketoacidosis (1.6%) with 82 (0.9 %) being diabetic ketoacidosis (DKA) and 48 (0.5%) alcoholic ketoacidosis (AKA) deaths. There were more male deaths in each group. The median age for DKA deaths was 51 years (range 19-79). The median age for AKA deaths was 55 years (range was 34-78). The BMI range in DKA deaths was 12.5 to 40.4 kg/m
    Language English
    Publishing date 2023-05-10
    Publishing country United States
    Document type Journal Article
    ISSN 1925-3621
    ISSN 1925-3621
    DOI 10.1177/19253621231167014
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Order via subito

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  7. Article ; Online: Letter From the Editor-In-Chief.

    Milroy, Christopher M

    Academic forensic pathology

    2018  Volume 8, Issue 3, Page(s) vi–vii

    Language English
    Publishing date 2018-08-31
    Publishing country United States
    Document type Editorial
    ISSN 1925-3621
    ISSN (online) 1925-3621
    DOI 10.1177/1925362118797771
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Order via subito

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  8. Article ; Online: Letter From the Editor-In-Chief.

    Milroy, Christopher M

    Academic forensic pathology

    2018  Volume 8, Issue 2, Page(s) vi–vii

    Language English
    Publishing date 2018-06-07
    Publishing country United States
    Document type Editorial
    ISSN 1925-3621
    ISSN (online) 1925-3621
    DOI 10.1177/1925362118785209
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Order via subito

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  9. Article ; Online: Letter From the Editor-In-Chief.

    Milroy, Christopher M

    Academic forensic pathology

    2018  Volume 8, Issue 4, Page(s) viii–ix

    Language English
    Publishing date 2018-12-19
    Publishing country United States
    Document type Editorial
    ISSN 1925-3621
    ISSN (online) 1925-3621
    DOI 10.1177/1925362118821506
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Fatty Liver and the Forensic Pathologist.

    Milroy, Christopher M

    Academic forensic pathology

    2018  Volume 8, Issue 2, Page(s) 296–310

    Abstract: Fatty liver is a common finding in clinical practice and at autopsy. It is most commonly seen associated with alcohol abuse and in non-alcoholic fatty liver disease (NAFLD). It may also be seen in many other conditions in both adults and children. It is ... ...

    Abstract Fatty liver is a common finding in clinical practice and at autopsy. It is most commonly seen associated with alcohol abuse and in non-alcoholic fatty liver disease (NAFLD). It may also be seen in many other conditions in both adults and children. It is now recognized that NAFLD, like alcoholic liver disease, may lead to end stage liver disease. Nonalcoholic fatty liver disease is associated with increased mortality from other disorders, particularly cardiovascular diseases. Fatty liver may be seen in many conditions that concern autopsy pathologists, including drug toxicity, anorexia, hepatic ischemia, and heatstroke. In infants, steatosis is common in sudden unexpected deaths. Fatty liver has been associated with sudden death and this review examines the pathology and role of fatty liver in sudden death.
    Language English
    Publishing date 2018-06-06
    Publishing country United States
    Document type Journal Article ; Review
    ISSN 1925-3621
    ISSN (online) 1925-3621
    DOI 10.1177/1925362118782061
    Database MEDical Literature Analysis and Retrieval System OnLINE

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