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Article ; Online: Recent advances in Otology: Current landscape and future direction.

Hosoya, Makoto / Kurihara, Sho / Koyama, Hajime / Komune, Noritaka

2024 Volume 51, Issue 3, Page(s) 605–616

Abstract: Hearing is an essential sensation, and its deterioration leads to a significant decrease in the quality of life. Thus, great efforts have been made by otologists to preserve and recover hearing. Our knowledge regarding the field of otology has progressed ...

Abstract	Hearing is an essential sensation, and its deterioration leads to a significant decrease in the quality of life. Thus, great efforts have been made by otologists to preserve and recover hearing. Our knowledge regarding the field of otology has progressed with advances in technology, and otologists have sought to develop novel approaches in the field of otologic surgery to achieve higher hearing recovery or preservation rates. This requires knowledge regarding the anatomy of the temporal bone and the physiology of hearing. Basic research in the field of otology has progressed with advances in molecular biology and genetics. This review summarizes the current views and recent advances in the field of otology and otologic surgery, especially from the viewpoint of young Japanese clinician-scientists, and presents the perspectives and future directions for several topics in the field of otology. This review will aid next-generation researchers in understanding the recent advances and future challenges in the field of otology.
Language	English
Publishing date	2024-03-28
Publishing country	Netherlands
Document type	Journal Article ; Review
ZDB-ID	604552-2
ISSN	1879-1476 ; 0385-8146
ISSN (online)	1879-1476
ISSN	0385-8146
DOI	10.1016/j.anl.2024.02.009
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Absolute phase retrieval of shiny objects using fringe projection and deep learning with computer-graphics-based images.

Ueda, Kazumasa / Ikeda, Kanami / Koyama, Osanori / Yamada, Makoto

Applied optics

2022 Volume 61, Issue 10, Page(s) 2750–2756

Abstract: Fringe projection profilometry is a high-precision method used to measure the 3D shape of an object by projecting sinusoidal fringes onto an object. However, fringes projected onto a metallic or shiny object are distorted nonlinearly, which causes ... ...

Abstract	Fringe projection profilometry is a high-precision method used to measure the 3D shape of an object by projecting sinusoidal fringes onto an object. However, fringes projected onto a metallic or shiny object are distorted nonlinearly, which causes significant measurement errors. A high-precision measurement method for shiny objects that employs computer graphics (CG) and deep learning is proposed. We trained a deep neural network by projecting fringes on a shiny object in CG space. Our results show that the method can reduce the nonlinear fringe distortion caused by gloss in real space.
Language	English
Publishing date	2022-04-26
Publishing country	United States
Document type	Journal Article
ISSN	1539-4522
ISSN (online)	1539-4522
DOI	10.1364/AO.450723
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Reliability and validity of eye-hand coordination pointing tests for older adults.

Saito, Kazuo / Suzuki, Makoto / Koyama, Maki / Yamamoto, Junichi / Futaki, Toshiko

Medicine

2023 Volume 102, Issue 46, Page(s) e36025

Abstract: To examine the reliability and validity of eye-hand coordination pointing with pencil test (EHCPPT), which evaluates the spatial and temporal displacement of rhythmic movements. One hundred and thirty-five older adults participated in our study. ... ...

Abstract	To examine the reliability and validity of eye-hand coordination pointing with pencil test (EHCPPT), which evaluates the spatial and temporal displacement of rhythmic movements. One hundred and thirty-five older adults participated in our study. Reproducibility of the EHCPPT was assessed by the participants tapping on the center of the circles using a tablet pen in response to 2 types of stimulus sound sequences (Test A and B) across 2 separate trials, the first and second half. Construct validity was assessed by comparison in the distances between ultimate and current processing abilities, based on the spatial and temporal displacement relationship across Test A and Test B. Concurrent validity was assessed by examining the relationship between the distances between ultimate and current processing abilities and the motor and cognitive functions. Spatial and temporal displacements showed an excellent intraclass correlation coefficient in both Tests A and B of EHCPPT. The distance between ultimate and current processing ability, based on the relationship of spatial and temporal displacement, was significantly shorter in Test A compared to Test B. Spatial and temporal displacements were correlated with motor and cognitive functions. The spatial and temporal displacements of EHCPPT indicated reproducibility and validity in older adults. The EHCPPT may serve as a rhythmic movement reflecting motor and cognitive functions.
MeSH term(s)	Humans ; Aged ; Reproducibility of Results ; Movement/physiology ; Cognition
Language	English
Publishing date	2023-11-20
Publishing country	United States
Document type	Journal Article
ZDB-ID	80184-7
ISSN	1536-5964 ; 0025-7974
ISSN (online)	1536-5964
ISSN	0025-7974
DOI	10.1097/MD.0000000000036025
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Article: [Staged Hybrid Repair of Extensive Thoracic Aortic Aneurysm with Right Aortic Arch and Isolated Left Subclavian Artery:Report of a Case].

Niki, Taiki / Yoshida, Kazufumi / Nakamura, Ken / Kinoshita, Makoto / Koyama, Tadaaki

Kyobu geka. The Japanese journal of thoracic surgery

2023 Volume 76, Issue 2, Page(s) 132–135

Abstract: A 69-year-old male was referred to our hospital due to extensive thoracic aortic aneurysm with right aortic arch and isolated left subclavian artery. We chose staged hybrid repair to avoid the risk of spinal cord injury and bilateral recurrent nerve ... ...

Abstract	A 69-year-old male was referred to our hospital due to extensive thoracic aortic aneurysm with right aortic arch and isolated left subclavian artery. We chose staged hybrid repair to avoid the risk of spinal cord injury and bilateral recurrent nerve paralysis. First, ascending aorta replacement with elephant trunk and reconstruction of the cervical branches were underwent. Second, we performed the thoracic endovascular aortic repair for aortic arch and descending aortic aneurysm. The postoperative course was satisfactory and, computed tomography (CT) showed successful aortic repair without any type of endoleak. He was discharged on the ninth day after the second operation. To our knowledge, this is the first report of surgical repair for an aortic aneurysm with right aortic arch and isolated subclavian artery.
MeSH term(s)	Male ; Humans ; Aged ; Aorta, Thoracic/diagnostic imaging ; Aorta, Thoracic/surgery ; Subclavian Artery/diagnostic imaging ; Subclavian Artery/surgery ; Aortic Aneurysm, Thoracic/diagnostic imaging ; Aortic Aneurysm, Thoracic/surgery ; Aortic Aneurysm/surgery ; Blood Vessel Prosthesis Implantation ; Treatment Outcome ; Stents ; Endovascular Procedures/methods
Language	Japanese
Publishing date	2023-01-31
Publishing country	Japan
Document type	Case Reports ; English Abstract ; Journal Article
ZDB-ID	603899-2
ISSN	0021-5252
ISSN	0021-5252
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Article ; Online: Improvement of an Automated Sample Injection System for Pillar Array Columns to Increase Analytical Reproducibility.

Kuroki, Hiroshi / Koyama, Hirotaka / Tsunoda, Makoto

Molecules (Basel, Switzerland)

2022 Volume 27, Issue 15

Abstract: In our previous study, we developed an automatic sample injection system for pillar array columns for quantitative analysis. An autosampler was used to maintain a constant sample injection volume. However, the sample was diluted during injection using ... ...

Abstract	In our previous study, we developed an automatic sample injection system for pillar array columns for quantitative analysis. An autosampler was used to maintain a constant sample injection volume. However, the sample was diluted during injection using the autosampler, thus deteriorating the analytical reproducibility. In this study, we have substituted the autosampler with a syringe pump to overcome the abovementioned problem and improve the system. Sample dilution was avoided by filling the entire capillary with the sample at a constant rate. This improved system also increased the analytical reproducibility. In the previous system, the relative standard deviation (RSD) exceeded 17% of the peak height for coumarin dyes. In contrast, the improved system decreased the RSD to the range 1.2-1.8%. The analytical reproducibility was evaluated by using five types of amino acids. The RSD of each peak height was within 3.0%, confirming good reproducibility. These results indicate that the sample injection method developed in this study can be applied to biological sample analyses as a simple quantitative analysis method for pillar array columns.
MeSH term(s)	Amino Acids ; Reproducibility of Results
Chemical Substances	Amino Acids
Language	English
Publishing date	2022-07-23
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	1413402-0
ISSN	1420-3049 ; 1431-5165 ; 1420-3049
ISSN (online)	1420-3049
ISSN	1431-5165 ; 1420-3049
DOI	10.3390/molecules27154715
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Article ; Online: Improvement of an Automated Sample Injection System for Pillar Array Columns to Increase Analytical Reproducibility

Hiroshi Kuroki / Hirotaka Koyama / Makoto Tsunoda

Molecules, Vol 27, Iss 15, p

2022 Volume 4715

Abstract	In our previous study, we developed an automatic sample injection system for pillar array columns for quantitative analysis. An autosampler was used to maintain a constant sample injection volume. However, the sample was diluted during injection using the autosampler, thus deteriorating the analytical reproducibility. In this study, we have substituted the autosampler with a syringe pump to overcome the abovementioned problem and improve the system. Sample dilution was avoided by filling the entire capillary with the sample at a constant rate. This improved system also increased the analytical reproducibility. In the previous system, the relative standard deviation (RSD) exceeded 17% of the peak height for coumarin dyes. In contrast, the improved system decreased the RSD to the range 1.2–1.8%. The analytical reproducibility was evaluated by using five types of amino acids. The RSD of each peak height was within 3.0%, confirming good reproducibility. These results indicate that the sample injection method developed in this study can be applied to biological sample analyses as a simple quantitative analysis method for pillar array columns.
Keywords	microchip ; on-chip liquid chromatography ; automation ; amino acids ; miniaturization ; Organic chemistry ; QD241-441
Subject code	600
Language	English
Publishing date	2022-07-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Prevalence of psychological distress, quality of life, and satisfaction among patients and family members following comprehensive genomic profiling testing: Protocol of the Quality of life for Cancer genomics and Advanced Therapeutics (Q-CAT) study.

Nishino, Makoto / Fujimori, Maiko / Koyama, Takafumi / Hirata, Makoto / Tanabe, Noriko / Shimizu, Toshio / Yamamoto, Noboru / Uchitomi, Yosuke

PloS one

2023 Volume 18, Issue 5, Page(s) e0283968

Abstract: Precision medicine is rapidly changing the diagnostic and treatment spectrum of oncology. In May 2019, comprehensive genomic profiling (CGP) (somatic and/or germline) was approved for reimbursement in Japan. While the promise of novel and targeted ... ...

Abstract	Precision medicine is rapidly changing the diagnostic and treatment spectrum of oncology. In May 2019, comprehensive genomic profiling (CGP) (somatic and/or germline) was approved for reimbursement in Japan. While the promise of novel and targeted therapies has elevated hopes for the benefits of CGP, the lack of relevant genomic findings and/or limited access to relevant therapies remain important themes in this field. These challenges may also negatively influence the psychology of both cancer patients and their family members. However, few studies have reported longitudinal data on quality of life (QOL) with CGP. Here, we report the protocol of a prospective study, Q-CAT (QOL for Cancer genomics and Advanced Therapeutics among patients and their family members), which aims to explore the mental burden on patients and families arising from the implementation of CGP testing by collecting real-world longitudinal data using outcomes obtained with an electronic patient report, known as ePRO. This study has been registered with the Japan Registry of Clinical Trials (jRCT1030200039).
MeSH term(s)	Humans ; Quality of Life ; Prevalence ; Prospective Studies ; Patient Satisfaction ; Neoplasms/genetics ; Neoplasms/therapy ; Neoplasms/epidemiology ; Genomics/methods ; Personal Satisfaction ; Psychological Distress
Language	English
Publishing date	2023-05-26
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2267670-3
ISSN	1932-6203 ; 1932-6203
ISSN (online)	1932-6203
ISSN	1932-6203
DOI	10.1371/journal.pone.0283968
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Thoracic endovascular aortic repair for traction-induced aortic avulsion injury in neurofibromatosis type 1.

Yoshida, Soshi / Yoshida, Kazufumi / Oka, Shojiro / Kinoshita, Makoto / Koyama, Tadaaki

Journal of vascular surgery cases and innovative techniques

2022 Volume 8, Issue 4, Page(s) 726–728

Abstract: Rupture of intercostal artery aneurysms has been reported in patients with neurofibromatosis type 1. Many reports have demonstrated the efficacy of endovascular interventions. Herein, we present a case of successful treatment with thoracic endovascular ... ...

Abstract	Rupture of intercostal artery aneurysms has been reported in patients with neurofibromatosis type 1. Many reports have demonstrated the efficacy of endovascular interventions. Herein, we present a case of successful treatment with thoracic endovascular aortic repair for traction-induced avulsion injury of the previously embolized intercostal artery. We further report the potential postoperative risk of rapid aneurysmal enlargement, possibly owing to changes in the thoracic arterial regional network. Even after successful treatment, vascular surgeons should pay attention to other aneurysmal events in the acute phase and avulsion injuries in the chronic phase. Close follow-up is essential.
Language	English
Publishing date	2022-10-17
Publishing country	United States
Document type	Case Reports
ISSN	2468-4287
ISSN	2468-4287
DOI	10.1016/j.jvscit.2022.10.006
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Short-term outcomes of laparoscopic and robotic distal gastrectomy for gastric cancer: Real-world evidence from a large-scale inpatient database in Japan.

Hondo, Nao / Yamamoto, Yuta / Nakabe, Takayo / Otsubo, Tetsuya / Kitazawa, Masato / Nakamura, Satoshi / Koyama, Makoto / Miyazaki, Satoru / Kataoka, Masahiro / Soejima, Yuji

Journal of surgical oncology

2024 Volume 129, Issue 5, Page(s) 922–929

Abstract: Background and objectives: Robotic distal gastrectomy (RDG) has been widely performed throughout Japan since it became insured in 2018. This study aimed to evaluate the short-term outcomes of RDG and laparoscopic distal gastrectomy (LDG) for gastric ... ...

Abstract	Background and objectives: Robotic distal gastrectomy (RDG) has been widely performed throughout Japan since it became insured in 2018. This study aimed to evaluate the short-term outcomes of RDG and laparoscopic distal gastrectomy (LDG) for gastric cancer using real-world data. Methods: A total of 4161 patients who underwent LDG (n = 3173) or RDG (n = 988) for gastric cancer between April 2018 and October 2022 were identified through the Japanese Diagnosis Procedure Combination Database, which covers 42 national university hospitals. The primary outcome was postoperative in-hospital mortality rate. The secondary outcomes were postoperative complication rates, time to diet resumption, and postoperative length of stay (LOS). Results: In-hospital mortality and postoperative complication rates in the RDG group were comparable with those in the LDG group (0.1% vs. 0.0%, p = 1.000, and 8.7% vs. 8.2%, p = 0.693, respectively). RDG was associated with a longer duration of anesthesia (325 vs. 262 min, p < 0.001), similar time to diet resumption (3 vs. 3 days, p < 0.001), and shorter postoperative LOS (10 vs. 11 days, p < 0.001) compared with LDG. Conclusions: RDG was performed safely and provided shorter postoperative LOS, since it became covered by insurance in Japan.
MeSH term(s)	Humans ; Robotic Surgical Procedures/methods ; Japan/epidemiology ; Stomach Neoplasms ; Inpatients ; Gastrectomy/methods ; Treatment Outcome ; Laparoscopy/methods ; Postoperative Complications/etiology ; Retrospective Studies
Language	English
Publishing date	2024-01-04
Publishing country	United States
Document type	Journal Article
ZDB-ID	82063-5
ISSN	1096-9098 ; 0022-4790
ISSN (online)	1096-9098
ISSN	0022-4790
DOI	10.1002/jso.27575
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Zs.A 706: Show issues

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Article ; Online: Prevalence of psychological distress, quality of life, and satisfaction among patients and family members following comprehensive genomic profiling testing

Makoto Nishino / Maiko Fujimori / Takafumi Koyama / Makoto Hirata / Noriko Tanabe / Toshio Shimizu / Noboru Yamamoto / Yosuke Uchitomi

PLoS ONE, Vol 18, Iss 5, p e

Protocol of the Quality of life for Cancer genomics and Advanced Therapeutics (Q-CAT) study.

2023 Volume 0283968

Abstract	Precision medicine is rapidly changing the diagnostic and treatment spectrum of oncology. In May 2019, comprehensive genomic profiling (CGP) (somatic and/or germline) was approved for reimbursement in Japan. While the promise of novel and targeted therapies has elevated hopes for the benefits of CGP, the lack of relevant genomic findings and/or limited access to relevant therapies remain important themes in this field. These challenges may also negatively influence the psychology of both cancer patients and their family members. However, few studies have reported longitudinal data on quality of life (QOL) with CGP. Here, we report the protocol of a prospective study, Q-CAT (QOL for Cancer genomics and Advanced Therapeutics among patients and their family members), which aims to explore the mental burden on patients and families arising from the implementation of CGP testing by collecting real-world longitudinal data using outcomes obtained with an electronic patient report, known as ePRO. This study has been registered with the Japan Registry of Clinical Trials (jRCT1030200039).
Keywords	Medicine ; R ; Science ; Q
Language	English
Publishing date	2023-01-01T00:00:00Z
Publisher	Public Library of Science (PLoS)
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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