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  1. Article: Evaluating the Impact of Training Teachers to Identify Learning Disabilities: A Pre-experimental Study on Knowledge Enhancement.

    Dani, Akanksha P / Pusdekar, Yamini V / Dagdiya, Ketan R / Deshmukh, Vishwajit R

    Cureus

    2024  Volume 16, Issue 3, Page(s) e55685

    Abstract: Introduction Learning disability (LD) affects many school-going children and is seldom recognized or treated. As teachers spend time with students, they can easily recognize LD by observing academic activities and behaviors. In this context, the present ... ...

    Abstract Introduction Learning disability (LD) affects many school-going children and is seldom recognized or treated. As teachers spend time with students, they can easily recognize LD by observing academic activities and behaviors. In this context, the present study was conducted to assess the knowledge and practices of teachers regarding LD and evaluate the impact of an educational intervention on teachers' knowledge regarding LD and its screening and referral. Methods A pre-experimental study, including pre-post interventional assessments of teachers, was conducted from June 2018 to December 2019. A universal sample of 150 teachers from 10 schools teaching primary (first to fifth grade) and upper primary (sixth to eight grade) grades was included. Their knowledge about LD was assessed using the Dyslexia Assessment for the Languages of India (DALI), and an educational intervention for assessing, screening, and identifying LD was implemented. Data was analyzed using SPSS version 24.0 (IBM Inc., Armonk, New York). Using descriptive statistics (mean, median, and standard deviation). The pre-post test results were compared using the McNemar test. Results Overall knowledge about LD was 24.7% at baseline, and improved to 76% post-intervention (p<0.001). The knowledge for most of the components showed improvement. Teachers with a good level of knowledge increased from 21% to 84%. Post-intervention screening of students increased from 0.53% to 13.37%. The suspicion rate for LD increased from 0.04% to 1.94% post-intervention. Conclusion Knowledge about LD was poor among the school teachers. However, the overall knowledge about LD, its specific domains, screening as well as actual LD screening significantly improved after the intervention (p<0.001). This emphasizes the need of training primary and post-primary school teachers about LD and the services available for children with LD.
    Language English
    Publishing date 2024-03-06
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.55685
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Insights with consensus on Abductor Pollicis Longus from the Central Indian population at Nagpur, Maharashtra.

    Deshmukh, Vishwajit / Talhar, Shweta / Muthiyan, Gayatri / Kasat, Payal / Chandrasekaran, Kirubhanand / Sontakke, Bharat

    Bioinformation

    2023  Volume 19, Issue 11, Page(s) 1111–1115

    Abstract: The anatomical snuff box is bounded laterally by the Abductor pollicis longus (APL) and the Extensor pollicis brevis (EPB) tendons. The variation in insertion of extensor tendons at the forearm and wrist is an interesting phenomenon. Therefore, a sound ... ...

    Abstract The anatomical snuff box is bounded laterally by the Abductor pollicis longus (APL) and the Extensor pollicis brevis (EPB) tendons. The variation in insertion of extensor tendons at the forearm and wrist is an interesting phenomenon. Therefore, a sound knowledge of such variations in extensor tendons is essential to know the consequence of tendon injury during implementation of its repair. Hence, we studied 48 formaldehyde fixed forearms of Indian-origin cadavers with age groups ranging from 33 to 67 years from the Central Indian population at Nagpur, Maharashtra, India. Variation in the insertion of APL was checked by tracing the tendon till its insertion. APL muscle was found with single tendon in 20 forearms, double in 9, triple in 8 and quadruple in 5 and five (maximum) in 6 forearms. In 93% (n=45), the APL tendon was inserted into the first metacarpal bone and in 7% (n=03), it was inserted into the trapezium bone. No variation was noted in the EPB tendon. Data shows that there are accessory slips in the APL tendon, differing from the standard description. Thus, data provides awareness of such potential variation among operating surgeons for better management of the diseased during dissection.
    Language English
    Publishing date 2023-11-30
    Publishing country Singapore
    Document type Journal Article
    ZDB-ID 2203786-X
    ISSN 0973-2063
    ISSN 0973-2063
    DOI 10.6026/973206300191111
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Renal Carcinoma Is Associated With Increased Risk of Coronavirus Infections.

    Tripathi, Satyendra C / Deshmukh, Vishwajit / Creighton, Chad J / Patil, Ashlesh

    Frontiers in molecular biosciences

    2020  Volume 7, Page(s) 579422

    Abstract: Background: ...

    Abstract Background:
    Language English
    Publishing date 2020-11-20
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2814330-9
    ISSN 2296-889X
    ISSN 2296-889X
    DOI 10.3389/fmolb.2020.579422
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: The Role of the Flipped Classroom Method in Short-Term and Long-Term Retention Among Undergraduate Medical Students of Anatomy.

    Kasat, Payal / Deshmukh, Vishwajit / Muthiyan, Gayatri / T S, Gugapriya / Sontakke, Bharat / Sorte, Smita R / Tarnekar, Aditya M

    Cureus

    2023  Volume 15, Issue 9, Page(s) e45021

    Abstract: Introduction Medical education is changing towards more flexible, effective, active, and student-centred teaching strategies that reduce the limitations of traditional methods of education. Recently, the flipped classroom method has been suggested to ... ...

    Abstract Introduction Medical education is changing towards more flexible, effective, active, and student-centred teaching strategies that reduce the limitations of traditional methods of education. Recently, the flipped classroom method has been suggested to support this transition. However, research on the use of flipped classroom methods in medical education pertaining to short- and long-term retention of the topics is at an early stage. The present paper aims to determine and compare the effects of traditional and flipped classroom methods on first-year medical students' short-term and long-term retention. Method Fifty first-year medical students were subjected to traditional and flipped classroom modules in the form of five sessions each on gross anatomy topics of the thoracic region. These sessions were conducted during independent teaching slots for anatomy. Assessments were done at the completion of each module for both methods. Then, after a gap of two months, the students were again assessed on the content taught in the modules as a part of formative assessment. The data so obtained were compared and analysed statistically. Ethical approval was obtained prior to beginning the study. Written informed consent was obtained from the participating students. Result A total of 50 first-year medical students participated in the study. 33 (67%) participants were males, with a median age of 19.47 years, and 17 (33%) participants were females, with a median age of 19.39 years. The assessment scores showed differences between the two methods of teaching in the short and long term. The flipped classroom method was observed to have significant short-term retention with a p-value <0.0001, which is statistically significant. Conclusion The study concludes that the flipped classroom method serves as an advantageous tool and motivating factor for effective learning, understanding, and retention of conceptual and factual anatomical content.
    Language English
    Publishing date 2023-09-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.45021
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Pathological involvement of placenta in COVID-19: a systematic review.

    Motwani, Rohini / Deshmukh, Vishwajit / Kumar, Ashutosh / Kumari, Chiman / Raza, Khursheed / Krishna, Hare

    Le infezioni in medicina

    2022  Volume 30, Issue 2, Page(s) 157–167

    Abstract: The mammalian placenta, which is responsible for bonding between the mother and the fetus, is one of the first organs to develop. Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) infection has caused a great threat to public health and ... ...

    Abstract The mammalian placenta, which is responsible for bonding between the mother and the fetus, is one of the first organs to develop. Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) infection has caused a great threat to public health and affected almost all the organs including the placenta. Owing to limited available data on vertical transmission and pathological changes in the placenta of SARS-CoV-2 positive patients, we aim to review and summarize histopathological and ultrastructural changes in the placental tissue following SARS-CoV-2 infection. Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2009 guidelines were used for review writing. Multiple studies have reported significant pathological changes in the placental tissue of SARS-CoV-2 positive mothers. On the other hand, some studies have demonstrated either no or very little involvement of the placental tissue. The most common pathological changes reported are fetal and maternal vascular malformation, villitis of unknown etiology, thrombus formation in the intervillous space and sub-chorionic space, and chorangiosis. Reports on vertical transmission are less in number. The observations of this review present a strong base for the pathological involvement of the placenta in SARS-CoV-2 infected mothers. However, a smaller number of original studies have been done until now, and most of them have small sample sizes and lack matched control groups, which are the big limitations for drawing an effective conclusion at this stage. Antenatal care can be improved by a better understanding of the correlation between maternal SARS-CoV-2 infection and placental pathology in COVID-19.
    Language English
    Publishing date 2022-06-01
    Publishing country Italy
    Document type Journal Article ; Review
    ZDB-ID 2041081-5
    ISSN 2532-8689 ; 1124-9390
    ISSN (online) 2532-8689
    ISSN 1124-9390
    DOI 10.53854/liim-3002-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Partial Duplication of the Left Ureter and Enlarged Left Suprarenal Gland - A Case Report.

    Sontakke, Bharat / Deshmukh, Vishwajit / C, Kirubhanand / Muthiyan, Gayatri / Ts, Gugapriya / Tarnekar, Aaditya

    Cureus

    2021  Volume 13, Issue 12, Page(s) e20848

    Abstract: During routine dissection classes for the first-year undergraduate medical students, we encountered an anatomical variation concerning the duplication of the ureter. Usually, a single ureter connects to the posterior renal hilum. In the present case, a ... ...

    Abstract During routine dissection classes for the first-year undergraduate medical students, we encountered an anatomical variation concerning the duplication of the ureter. Usually, a single ureter connects to the posterior renal hilum. In the present case, a double ureter arises from the hilum on the left side and an enlarged suprarenal gland. The accessory ureter travels a short distance from the hilum before joining the other ureter. These anomalies are becoming more common during renal surgeries and renal transplant surgeries. Damage to the accessory ureter may result in complications following surgery. Knowledge of an accessory ureter and an enlarged suprarenal gland is clinically important for renal surgeons, radiologists, and anatomists.
    Language English
    Publishing date 2021-12-31
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.20848
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Histopathological observations in COVID-19: a systematic review.

    Deshmukh, Vishwajit / Motwani, Rohini / Kumar, Ashutosh / Kumari, Chiman / Raza, Khursheed

    Journal of clinical pathology

    2020  Volume 74, Issue 2, Page(s) 76–83

    Abstract: Background: Coronavirus disease-2019 (COVID-19) has caused a great global threat to public health. The World Health Organization (WHO) has declared COVID-19 disease as a pandemic, affecting the human respiratory and other body systems, which urgently ... ...

    Abstract Background: Coronavirus disease-2019 (COVID-19) has caused a great global threat to public health. The World Health Organization (WHO) has declared COVID-19 disease as a pandemic, affecting the human respiratory and other body systems, which urgently demands for better understanding of COVID-19 histopathogenesis.
    Objective: Data on pathological changes in different organs are still scarce, thus we aim to review and summarise the latest histopathological changes in different organs observed after autopsy of COVID-19 cases.
    Materials and methods: Over the period of 3 months, authors performed vast review of the articles. The search engines included were PubMed, Medline (EBSCO & Ovid), Google Scholar, Science Direct, Scopus and Bio-Medical. Search terms used were 'Histopathology in COVID-19', 'COVID-19', 'Pathological changes in different organs in COVID-19' or 'SARS-CoV-2'. Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2009 guidelines were used for review writing.
    Result: We identified various articles related to the histopathology of various organs in COVID-19 positive patients. Overall, 45 articles were identified as full articles to be included in our study. Histopathological findings observed are summarised according to the systems involved.
    Conclusion: Although COVID-19 mainly affects respiratory and immune systems, but other systems like cardiovascular, urinary, gastrointestinal tract, reproductive system, nervous system and integumentary system are not spared, especially in elderly cases and those with comorbidity. This review would help clinicians and researchers to understand the tissue pathology, which can help in better planning of the management and avoiding future risks.
    MeSH term(s) COVID-19/pathology ; Humans ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-08-18
    Publishing country England
    Document type Journal Article ; Systematic Review
    ZDB-ID 80261-x
    ISSN 1472-4146 ; 0021-9746
    ISSN (online) 1472-4146
    ISSN 0021-9746
    DOI 10.1136/jclinpath-2020-206995
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: COVID 19 diagnostic multiplicity and its role in community surveillance and control.

    Tripathi, Satyendra C / Deshmukh, Vishwajit / Patil, Ashlesh / Tripathy, Jaya Prasad

    Le infezioni in medicina

    2020  Volume 28, Issue suppl 1, Page(s) 18–28

    Abstract: Diagnosis of persons exposed to/infected with severe acute respiratory syndrome-related coronavirus-2 (SARS-CoV-2) is central to controlling the global pandemic of COVID-19. Currently, several diagnostic modalities are available for COVID-19, each with ... ...

    Abstract Diagnosis of persons exposed to/infected with severe acute respiratory syndrome-related coronavirus-2 (SARS-CoV-2) is central to controlling the global pandemic of COVID-19. Currently, several diagnostic modalities are available for COVID-19, each with its own pros and cons. Although there is a global consensus to increase the testing capacity, it is also essential to prudently utilize these tests to control the pandemic. In this paper, we have reviewed the current array of diagnostics for SARS-CoV-2, highlighted the gaps in current diagnostic modalities, and their role in community surveillance and control of the pandemic. The different modalities of COVID-19 diagnosis discussed are: clinical and radiological, molecular based (laboratory based and point-of-care), Immunoassay based (ELISA, rapid antigen and antibody detection tests) and digital diagnostics (artificial intelligence based algorithms). The role of rapid antigen/antibody detection tests in community surveillance has also been described here. These tests can be used to identify asymptomatic persons exposed to the virus and in community based seroprevalence surveys to assess the epidemiology of spread of the virus. However, there are few concerns about the accuracy of these tests which needs to evaluated beforehand.
    MeSH term(s) Algorithms ; Antibodies, Viral/analysis ; Antigens, Viral/analysis ; Artificial Intelligence ; Asymptomatic Diseases ; Betacoronavirus/genetics ; Betacoronavirus/immunology ; Betacoronavirus/isolation & purification ; Betacoronavirus/physiology ; Body Fluids/virology ; COVID-19 ; COVID-19 Testing ; Clinical Laboratory Techniques/methods ; Coronavirus Infections/diagnosis ; Coronavirus Infections/epidemiology ; Coronavirus Infections/prevention & control ; Coronavirus Infections/transmission ; Enzyme-Linked Immunosorbent Assay ; Humans ; Molecular Diagnostic Techniques ; Nasopharynx/virology ; Pandemics/prevention & control ; Pneumonia, Viral/diagnosis ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/prevention & control ; Pneumonia, Viral/transmission ; Point-of-Care Testing ; Population Surveillance ; Procedures and Techniques Utilization ; RNA, Viral/analysis ; Reverse Transcriptase Polymerase Chain Reaction/methods ; SARS-CoV-2 ; Sputum/virology ; Symptom Assessment ; Viral Load
    Chemical Substances Antibodies, Viral ; Antigens, Viral ; RNA, Viral
    Keywords covid19
    Language English
    Publishing date 2020-06-12
    Publishing country Italy
    Document type Journal Article ; Review
    ZDB-ID 2041081-5
    ISSN 1124-9390
    ISSN 1124-9390
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Corrigendum to: Possible modulation of PPAR-γ cascade against depression caused by neuropathic pain in rats.

    Garg, Shanky / Prasoon, Pranav / Deshmukh, Vishwajit Ravindra / Goyal, Rohit

    Journal of basic and clinical physiology and pharmacology

    2018  Volume 29, Issue 2, Page(s) 225

    Language English
    Publishing date 2018-02-26
    Publishing country Germany
    Document type Journal Article ; Published Erratum
    ZDB-ID 1071737-7
    ISSN 2191-0286 ; 0792-6855 ; 0334-1534
    ISSN (online) 2191-0286
    ISSN 0792-6855 ; 0334-1534
    DOI 10.1515/jbcpp-2017-0213
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Renal Carcinoma Is Associated With Increased Risk of Coronavirus Infections

    Satyendra C. Tripathi / Vishwajit Deshmukh / Chad J. Creighton / Ashlesh Patil

    Frontiers in Molecular Biosciences, Vol

    2020  Volume 7

    Abstract: Background: The current COVID-19 pandemic has affected most severely people with old age, or with comorbidities like hypertension, diabetes mellitus, and cancer. Cancer patients are twice more likely to contract the disease because of the malignancy or ... ...

    Abstract Background: The current COVID-19 pandemic has affected most severely people with old age, or with comorbidities like hypertension, diabetes mellitus, and cancer. Cancer patients are twice more likely to contract the disease because of the malignancy or treatment-related immunosuppression; hence identification of the vulnerable population among these patients is essential.Method: We took a bioinformatics approach to analyze the gene and protein expression data of these coronavirus receptors (DPP4, ANPEP, ENPEP, TMPRSS2) in human normal and cancer tissues of multiple organs including the brain, liver, kidney, heart, lung, skin, GI tract, pancreas, endocrine tissues, and the reproductive organs. RNA-Seq data from The Cancer Genome Atlas (TCGA) and GTeX databases were used for extensive profiling analysis of these receptors across 9,736 tumors and 8,587 normal tissues comparing coronavirus receptors. Protein expression from immunohistochemistry data was assessed from The Human Protein Atlas database including 144 samples, corresponding to 48 different normal human tissue types, and 432 tumor samples from 216 different cancer patients. The correlations between immune cell infiltration, chemokine, and cytokines were investigated via Tumor Immune Estimation Resource (TIMER) and TCGA.Result: We found that among all, renal tumor and normal tissues exhibited increased levels of ACE2, DPP4, ANPEP, and ENPEP. Our results revealed that TMPRSS2 may not be the co-receptor for coronavirus infection in renal carcinoma patients. The other receptors DPP4, ANPEP, and ENPEP may act as the compensatory receptor proteins to help ACE2. The receptors' expression levels were variable in different tumor stage, molecular, and immune subtypes of renal carcinoma. Intriguingly, in clear cell renal cell carcinomas, coronavirus receptors were associated with high immune infiltration, markers of immunosuppression, and T cell exhaustion.Conclusion: Our study indicates that CoV receptors may play an important role in modulating the immune ...
    Keywords coronavirus ; cancer ; kidney ; ACE2 ; DPP4 ; tmprss2 ; Biology (General) ; QH301-705.5
    Subject code 616
    Language English
    Publishing date 2020-11-01T00:00:00Z
    Publisher Frontiers Media S.A.
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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