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Article: Advances on plant miR169/NF-YA regulation modules.

Xu, Miao-yun / Zhu, Jia-xu / Zhang, Min / Wang, Lei

Yi chuan = Hereditas

2016 Volume 38, Issue 8, Page(s) 700–706

Abstract: ... and experimental analyses suggest that miR169 targets members of the transcription factor NF-YA gene ... In addition, a comprehensive understanding the regulatory functions of the miR169/NF-YA module in plant ...

Abstract	Plant microRNAs (miRNAs) are a class of small non-coding RNAs which target and regulate the expression of genes involved in several growth, development, and metabolism processes. The miR169 family is the largest and most conserved miRNA family in plants. Recent researches have shown involvement of miR169 members in the regulation of plant responding to abiotic stress and development. Computational prediction and experimental analyses suggest that miR169 targets members of the transcription factor NF-YA gene family. In this review, we summarize the origins, evolution and diversity of miR169 family members. In addition, a comprehensive understanding the regulatory functions of the miR169/NF-YA module in plant with particular emphasis on stress-induced flowering is discussed.
MeSH term(s)	Flowers/genetics ; Gene Expression Regulation, Plant/genetics ; Genes, Plant/genetics ; MicroRNAs/genetics ; RNA, Plant/genetics ; Stress, Physiological/genetics ; Transcription Factors/genetics
Chemical Substances	MicroRNAs ; RNA, Plant ; Transcription Factors
Language	English
Publishing date	2016
Publishing country	China
Document type	Journal Article ; Review
ISSN	0253-9772
ISSN	0253-9772
DOI	10.16288/j.yczz.15-526
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Theaflavoids A-C, new flavan-3-ols with potent α-glucosidase inhibitory activity from Yunnan black tea 'Jin-Ya'

Li, Na / Chen, Min / Zhu, Hong-Tao / Zhang, Man / Wang, Dong / Yang, Chong-Ren / Zhang, Ying-Jun

Lebensmittel-Wissenschaft + Technologie. 2022 Oct. 01, v. 168

2022

Abstract: ... The extensive investigation on the chemical constituents of Yunnan black tea 'Jin-Ya', produced from the leaf ... only moderate activities. The results indicated that Yunnan black tea 'Jin-Ya' is an ideal drink ...

Abstract	Black tea, rich in various and complex polyphenols, is one of the most popular beverages in the world due to its pleasant aroma and health benefits, such as alleviate hyperglycemia and antioxidant. The extensive investigation on the chemical constituents of Yunnan black tea 'Jin-Ya', produced from the leaf buds of Camellia sinensis var. assamica, led to the isolation and identification of 16 flavonoids including three new flavan-3-ols, namely theaflavoids A-C (1–3). Most of the isolates displayed obvious inhibitory activity on α-glucosidase with IC₅₀ values ranging from 1.11 to 24.7 μM. Notably, the new theaflavoids 1–3 showed much stronger inhibitory activity (IC₅₀ = 1.34, 1.11, and 4.57 μM, respectively) than those of the positive controls (acarbose and quercetin, IC₅₀ = 228 and 9.38 μM, respectively). In addition, the isolated flavonol glycosides 5–16 were evaluated for their antioxidant activities by DPPH and ABTS ⁺ radical scavenging assays. Those with galloyl group in molecular exhibited comparable free radical scavenging activities to the positive controls (ascorbic acid and Trolox), while most of the flavonol glycosides showed only moderate activities. The results indicated that Yunnan black tea 'Jin-Ya' is an ideal drink with hypoglycemic and antioxidant property, and is worthy of regular consumption.
Keywords	Camellia sinensis var. assamica ; acarbose ; antioxidant activity ; antioxidants ; ascorbic acid ; black tea ; flavanols ; free radicals ; glycosides ; hyperglycemia ; leaves ; odors ; polyphenols ; quercetin ; China
Language	English
Dates of publication	2022-1001
Publishing place	Elsevier Ltd
Document type	Article
ZDB-ID	241369-3
ISSN	0460-1173 ; 0023-6438
ISSN	0460-1173 ; 0023-6438
DOI	10.1016/j.lwt.2022.113918
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: New Flavoalkaloids with Potent α-Glucosidase and Acetylcholinesterase Inhibitory Activities from Yunnan Black Tea 'Jin-Ya'.

Li, Na / Zhu, Hong-Tao / Wang, Dong / Zhang, Man / Yang, Chong-Ren / Zhang, Ying-Jun

Journal of agricultural and food chemistry

2020 Volume 68, Issue 30, Page(s) 7955–7963

Abstract: As a subgroup of flavoalkaloids, ...

Abstract	As a subgroup of flavoalkaloids,
MeSH term(s)	Acetylcholinesterase/chemistry ; Alkaloids/chemistry ; Camellia sinensis/chemistry ; China ; Enzyme Inhibitors/chemistry ; Glycosides/chemistry ; Humans ; Kinetics ; Molecular Structure ; Plant Extracts/chemistry ; Plant Leaves/chemistry ; alpha-Glucosidases/chemistry
Chemical Substances	Alkaloids ; Enzyme Inhibitors ; Glycosides ; Plant Extracts ; Acetylcholinesterase (EC 3.1.1.7) ; alpha-Glucosidases (EC 3.2.1.20)
Language	English
Publishing date	2020-07-14
Publishing country	United States
Document type	Journal Article
ZDB-ID	241619-0
ISSN	1520-5118 ; 0021-8561
ISSN (online)	1520-5118
ISSN	0021-8561
DOI	10.1021/acs.jafc.0c02401
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Zs.A 1172: Show issues

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Article ; Online: Landslide Detection in the Linzhi–Ya’an Section along the Sichuan–Tibet Railway Based on InSAR and Hot Spot Analysis Methods

Jinmin Zhang / Wu Zhu / Yiqing Cheng / Zhenhong Li

Remote Sensing, Vol 13, Iss 3566, p

2021 Volume 3566

Abstract: Construction of the 998.64-km Linzhi–Ya’an section of the Sichuan–Tibet Railway has been influenced ... images were collected to detect landslide disasters along the entire Linzhi–Ya’an section. Interferogram ... Finally, 517 landslide disasters along the Linzhi–Ya’an route were detected by integrating observed ...

Abstract	Construction of the 998.64-km Linzhi–Ya’an section of the Sichuan–Tibet Railway has been influenced by landslide disasters, threatening the safety of Sichuan–Tibet railway projects. Landslide identification and deformation analysis in this area are urgently needed. In this context, it was the first time that 164 advanced land-observing satellite-2 (ALOS-2) phased array type L-band synthetic aperture radar-2 (PALSAR-2) images were collected to detect landslide disasters along the entire Linzhi–Ya’an section. Interferogram stacking and small baseline interferometry methods were used to derive the deformation rate and time-series deformation from 2014–2020. After that, the hot spot analysis method was introduced to conduct spatial clustering analysis of the annual deformation rate, and the effective deformation area was quickly extracted. Finally, 517 landslide disasters along the Linzhi–Ya’an route were detected by integrating observed deformation, Google Earth optical images, and external geological data. The main factors controlling the spatial landslide distribution were analyzed. In the vertical direction, the spatial landslide distribution was mainly concentrated in the elevation range of 3000–5000 m, the slope range of 10–40°, and the aspect of northeast and east. In the horizontal direction, landslides were concentrated near rivers, and were also closely related to earthquake-prone areas, fault zones, and high-precipitation areas. In short, rainfall, freeze–thaw weathering, seismic activity, and fault zones are the main factors inducing landslides along this route. This research provides scientific support for the construction and operation of the Linzhi–Ya’an section of the Sichuan–Tibet Railway.
Keywords	landslide detection ; Sichuan–Tibet Railway ; interferometric synthetic aperture radar (InSAR) ; hot spot analysis ; Science ; Q
Subject code	550
Language	English
Publishing date	2021-09-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Landslide Detection in the Linzhi–Ya’an Section along the Sichuan–Tibet Railway Based on InSAR and Hot Spot Analysis Methods

Zhang, Jinmin / Zhu, Wu / Cheng, Yiqing / Li, Zhenhong

Remote Sensing. 2021 Sept. 08, v. 13, no. 18

2021

Abstract	Construction of the 998.64-km Linzhi–Ya’an section of the Sichuan–Tibet Railway has been influenced by landslide disasters, threatening the safety of Sichuan–Tibet railway projects. Landslide identification and deformation analysis in this area are urgently needed. In this context, it was the first time that 164 advanced land-observing satellite-2 (ALOS-2) phased array type L-band synthetic aperture radar-2 (PALSAR-2) images were collected to detect landslide disasters along the entire Linzhi–Ya’an section. Interferogram stacking and small baseline interferometry methods were used to derive the deformation rate and time-series deformation from 2014–2020. After that, the hot spot analysis method was introduced to conduct spatial clustering analysis of the annual deformation rate, and the effective deformation area was quickly extracted. Finally, 517 landslide disasters along the Linzhi–Ya’an route were detected by integrating observed deformation, Google Earth optical images, and external geological data. The main factors controlling the spatial landslide distribution were analyzed. In the vertical direction, the spatial landslide distribution was mainly concentrated in the elevation range of 3000–5000 m, the slope range of 10–40°, and the aspect of northeast and east. In the horizontal direction, landslides were concentrated near rivers, and were also closely related to earthquake-prone areas, fault zones, and high-precipitation areas. In short, rainfall, freeze–thaw weathering, seismic activity, and fault zones are the main factors inducing landslides along this route. This research provides scientific support for the construction and operation of the Linzhi–Ya’an section of the Sichuan–Tibet Railway.
Keywords	Internet ; deformation ; freeze-thaw cycles ; geophysics ; interferometry ; landslides ; railroads ; rain ; time series analysis
Language	English
Dates of publication	2021-0908
Publishing place	Multidisciplinary Digital Publishing Institute
Document type	Article
ZDB-ID	2513863-7
ISSN	2072-4292
ISSN	2072-4292
DOI	10.3390/rs13183566
Database	NAL-Catalogue (AGRICOLA)

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Article: New Flavoalkaloids with Potent α-Glucosidase and Acetylcholinesterase Inhibitory Activities from Yunnan Black Tea ‘Jin-Ya’

Li, Na / Zhu, Hong-Tao / Wang, Dong / Zhang, Man / Yang, Chong-Ren / Zhang, Ying-Jun

Journal of agricultural and food chemistry. 2020 July 06, v. 68, no. 30

2020

Abstract: ... ols in ‘Jin-Ya’, which is a Yunnan black tea produced only from the buds of the tea plant ...

Abstract	As a subgroup of flavoalkaloids, N-ethyl-2-pyrrolidinone substituted flavan-3-ols are reported to possess various biological activities that may play important roles in the beneficial healthcare functions of tea. The HPLC and LC-MS analyses showed the existence of N-ethyl-2-pyrrolidinone substituted flavan-3-ols in ‘Jin-Ya’, which is a Yunnan black tea produced only from the buds of the tea plant Camellia sinensis var. assamica. Further phytochemical study on this precious black tea led to the identification of 8 flavoalkaloids, 1–8, along with 11 known flavan-3-ols (9–14) and flavonol glycosides (15–19). The new compounds, (−)-6-(5″S)-N-ethyl-2-pyrrolidinone-epiafzelechin (1), (−)-8-(5″R)-N-ethyl-2-pyrrolidinone-epiafzelechin-3-O-gallate (2a), and (−)-8-(5″S)-N-ethyl-2-pyrrolidinone-epiafzelechin-3-O-gallate (2b), were identified based on extensive spectroscopic analysis. Flavoalkaloids 2–6 showed inhibitory activity on α-glucosidase with IC₅₀ values ranging from 2.09 to 8.47 μM, compared to those of quercetin and acarbose (IC₅₀ = 6.87 and 228.9 μM, respectively). Moreover, compounds 2, 3, and 6 displayed an inhibitory effect on acetyl-cholinesterase with IC₅₀ values of 14.23, 33.79, and 34.82 μM, respectively, compared to tacrine (IC₅₀ = 0.223 μM).
Keywords	Camellia sinensis var. assamica ; acarbose ; acetylcholinesterase ; black tea ; flavanols ; food chemistry ; glycosides ; health services ; quercetin ; spectral analysis ; China
Language	English
Dates of publication	2020-0706
Size	p. 7955-7963.
Publishing place	American Chemical Society
Document type	Article
Note	NAL-AP-2-clean
ZDB-ID	241619-0
ISSN	1520-5118 ; 0021-8561
ISSN (online)	1520-5118
ISSN	0021-8561
DOI	10.1021/acs.jafc.0c02401
Database	NAL-Catalogue (AGRICOLA)

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Article: NF-Ya activates multiple hematopoietic stem cell (HSC) regulatory genes and promotes HSC self-renewal.

Zhu, Jiang / Zhang, Yi / Joe, Gerard J / Pompetti, Richard / Emerson, Stephen G

Proceedings of the National Academy of Sciences of the United States of America

2005 Volume 102, Issue 33, Page(s) 11728–11733

Abstract: ... that NF-Ya, the regulatory and DNA-binding subunit of the trimeric transcription factor NF-Y, plays ... a central, integrating role in several of these HSC pathways. NF-Ya is preferentially expressed in HSC ... enriched bone marrow subpopulations, and NF-Ya mRNA rapidly declines with HSC differentiation ...

Abstract	Hematopoietic stem cell (HSC) self-renewal and differentiation are influenced through multiple pathways, including homeobox transcription factors, signaling through beta-catenin and Notch-1, telomerase, and p27. How these multiple pathways interact and are orchestrated is currently unknown. We now report that NF-Ya, the regulatory and DNA-binding subunit of the trimeric transcription factor NF-Y, plays a central, integrating role in several of these HSC pathways. NF-Ya is preferentially expressed in HSC-enriched bone marrow subpopulations, and NF-Ya mRNA rapidly declines with HSC differentiation. Overexpression of NF-Ya in primitive hematopoietic cells activates the transcription of multiple HOX4 paralogs, as well as Notch-1, LEF-1, and telomerase RNA. HSCs overexpressing NF-Ya are biased toward primitive hematopoiesis in vitro and show strikingly increased in vivo repopulating abilities after single or sequential bone marrow transplantation. Thus, NF-Ya is a potent cellular regulator of HSC self-renewal.
MeSH term(s)	Animals ; CCAAT-Binding Factor/genetics ; CCAAT-Binding Factor/metabolism ; Cell Proliferation ; Cells, Cultured ; Female ; Gene Expression Regulation/genetics ; Hematopoietic Stem Cells/cytology ; Hematopoietic Stem Cells/metabolism ; Homeodomain Proteins/genetics ; Male ; Mice ; Phenotype ; Promoter Regions, Genetic/genetics ; Regeneration ; Transcription Factors/genetics ; Transcription Factors/metabolism
Chemical Substances	CCAAT-Binding Factor ; Homeodomain Proteins ; Hoxb4 protein, mouse ; NFYA protein, human ; Transcription Factors
Language	English
Publishing date	2005-08-16
Publishing country	United States
Document type	Journal Article
ZDB-ID	209104-5
ISSN	1091-6490 ; 0027-8424
ISSN (online)	1091-6490
ISSN	0027-8424
DOI	10.1073/pnas.0503405102
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Zs.A 1148: Show issues

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Book: Zhongguo dong Ya fei huang fa sheng yu zhi li

Zhu, Enlin

1999

Author's details	Zhu Enlin zhu bian
Keywords	Migratory locust ; Migratory locust/Control
Language	Chinese
Size	2, 3, 7, 576 p. :, ill. (some col.), maps ;, 27 cm.
Edition	Di 1 ban.
Publisher	Zhongguo nong ye chu ban she ; Xin hua shu dian Beijing fa xing suo fa xing
Publishing place	Beijing Shi
Document type	Book
ISBN	7109056163 ; 9787109056169
Database	NAL-Catalogue (AGRICOLA)

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Book ; Thesis: Complex effects of iPLA2β deficiency on hepatic lipid metabolism in methionine-choline-deficient diet-induced fatty liver

Zhu, Xingya

2018

Author's details	vorgelegt von Xingya Zhu
Language	English
Size	82 Seiten, Illustrationen, Diagramme, 30 cm
Publishing place	Heidelberg
Publishing country	Germany
Document type	Book ; Thesis
Thesis / German Habilitation thesis	Dissertation, Ruprecht-Karls-Universität Heidelberg, 2019
Note	Im Titel ist "2" tiefgestellt
HBZ-ID	HT020239884
Database	Catalogue ZB MED Medicine, Health

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Shelf mark	Loan status	Location
2019 E 1144	order for loan	Magazin

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Book: Ya ge

Wang, Fumin / Zhu, Yixiong / Gordis, Robert / Ting, Simon

The song of songs

1959

Title translation	Bible. <Song of Solomon.> <engl.>. Gordis., 1960.
Title variant	Bible. <Song of Solomon.> . Revised Standard., 1960. ; Song of songs
Author's details	[Ying yi zhe Gedisi yu biao zhun xiu zheng ban xue zhe; Han yi zhe Wang Fumin; cha hua zhe Zhu Yixiong]
Language	Chinese ; English
Size	4, 1, 175 p., [8] leaves of plates, col. ill
Document type	Book
Note	Title in Hebrew, Chinese, English, Greek, and Latin
Database	Former special subject collection: coastal and deep sea fishing

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