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Article ; Online: Cutting edge: a further response.

Patel, Lopa / Al-Himdani, Sarah

2015 Volume 12, Issue 2, Page(s) 144

MeSH term(s)	General Surgery/education ; Humans ; Teaching/methods
Language	English
Publishing date	2015-04
Publishing country	England
Document type	Comment ; Letter
ZDB-ID	2151518-9
ISSN	1743-498X ; 1743-4971
ISSN (online)	1743-498X
ISSN	1743-4971
DOI	10.1111/tct.12365
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Article ; Online: Group C streptococcal septic arthritis of a prosthetic hip joint following dental treatment.

Al-Himdani, Sarah / Woodnutt, David

BMJ case reports

2015 Volume 2015

Abstract: We report a case of a prosthetic joint infection occurring secondary to group C Streptococcus following dental treatment in a 66-year-old woman. This patient presented 11 years following a right hip resurfacing procedure with increasing pain and ... ...

Abstract	We report a case of a prosthetic joint infection occurring secondary to group C Streptococcus following dental treatment in a 66-year-old woman. This patient presented 11 years following a right hip resurfacing procedure with increasing pain and difficulty mobilising the right hip. An ultrasound and MRI scan identified a collection in the right hip joint, which was subsequently aspirated. Cultures revealed a group C Streptococcus. Extensive washout and surgical debridement of the hip joint was undertaken and the patient was treated with a protracted course of antibiotics. At 1 year follow-up, the patient demonstrated no evidence of recurrent infection. We discuss the evidence underlying prophylactic antibiotic usage regarding dental procedures in the prevention of septic arthritis in patients with prosthetic joints. We also review the spectrum of diseases caused by this organism.
MeSH term(s)	Anti-Bacterial Agents/therapeutic use ; Antibiotic Prophylaxis ; Arthritis, Infectious/diagnosis ; Arthritis, Infectious/drug therapy ; Arthritis, Infectious/surgery ; Debridement ; Diagnosis, Differential ; Female ; Hip Prosthesis ; Humans ; Middle Aged ; Prosthesis-Related Infections/diagnosis ; Prosthesis-Related Infections/drug therapy ; Prosthesis-Related Infections/surgery ; Root Canal Therapy/adverse effects ; Streptococcal Infections/diagnosis ; Streptococcal Infections/drug therapy ; Streptococcal Infections/surgery
Chemical Substances	Anti-Bacterial Agents
Language	English
Publishing date	2015-10-22
Publishing country	England
Document type	Case Reports ; Journal Article
ISSN	1757-790X
ISSN (online)	1757-790X
DOI	10.1136/bcr-2015-211203
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Article ; Online: Periorbital necrotising fasciitis with underlying undiagnosed hepatitis C infection.

Cereceda-Monteoliva, Nicholas / Lewis, Hannah / Al-Himdani, Sarah / Stone, Christopher

BMJ case reports

2019 Volume 12, Issue 4

Abstract: We report the case of a 56-year-old man, previously well, who presented with a spontaneous right-sided periorbital necrotising soft tissue infection and subsequently found to have undiagnosed hepatitis C and liver cirrhosis. The patient presented with ... ...

Abstract	We report the case of a 56-year-old man, previously well, who presented with a spontaneous right-sided periorbital necrotising soft tissue infection and subsequently found to have undiagnosed hepatitis C and liver cirrhosis. The patient presented with rapid onset right eye pain, periorbital swelling and septic shock. CT scan revealed diffuse inflammatory changes to the soft tissue anterior to the right eye. The initial treatment included intravenous antibiotics, emergency debridement of necrotic tissue and admission to intensive care. Group A streptococcus was cultured from the debrided tissue. The patient developed decompensated liver failure and life-threatening haematemesis. Liver screening detected hepatitis C positive serology, the only risk factor for which was an old tattoo. The patient was effectively managed by early involvement of multiple clinical teams. We review the literature surrounding periorbital necrotising fasciitis, discuss the evidence for hepatic disorders as a potential cause and make recommendations for managing these patients.
MeSH term(s)	Administration, Intravenous ; Anti-Bacterial Agents/administration & dosage ; Anti-Bacterial Agents/therapeutic use ; Debridement/methods ; Diagnosis, Differential ; Fasciitis, Necrotizing/drug therapy ; Fasciitis, Necrotizing/etiology ; Fasciitis, Necrotizing/microbiology ; Fasciitis, Necrotizing/surgery ; Hepatitis C/complications ; Hepatitis C/diagnosis ; Humans ; Liver Cirrhosis/complications ; Liver Cirrhosis/diagnosis ; Liver Cirrhosis/surgery ; Male ; Middle Aged ; Orbital Diseases/diagnostic imaging ; Orbital Diseases/microbiology ; Orbital Diseases/pathology ; Streptococcal Infections/diagnosis ; Streptococcal Infections/drug therapy ; Streptococcus/isolation & purification ; Tomography, X-Ray Computed/methods ; Treatment Outcome
Chemical Substances	Anti-Bacterial Agents
Language	English
Publishing date	2019-04-23
Publishing country	England
Document type	Case Reports ; Journal Article
ISSN	1757-790X
ISSN (online)	1757-790X
DOI	10.1136/bcr-2017-223720
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Article: An 18-year Study of Malignant Melanoma in Childhood and Adolescence.

Al-Himdani, Sarah / Naderi, N / Whitaker, I S / Jones, N W

Plastic and reconstructive surgery. Global open

2019 Volume 7, Issue 8, Page(s) e2338

Abstract: Malignant melanoma is rare in childhood and adolescence. Diagnostic uncertainty and misdiagnosis often lead to delayed treatment.: Methods: We evaluated children and adolescents under 20 years of age presenting with malignant melanoma at our ... ...

Abstract	Malignant melanoma is rare in childhood and adolescence. Diagnostic uncertainty and misdiagnosis often lead to delayed treatment. Methods: We evaluated children and adolescents under 20 years of age presenting with malignant melanoma at our institution over an 18-year period. Data were collected, analyzed, and interpreted, following which findings were compared with the existing literature. Results: Twenty-four patients were included in the study with mean follow-up of 61.8 months. Males comprised 54% of cases. On presentation, 33% of children had melanoma of s thickness 2-4 mm and 34% had stage III disease. Younger children presented with thicker melanomas, differing subtypes, and more advanced stage disease compared with older children. Extremities were the most common sites affected (42%). Dissection of the draining lymph node basins was undertaken in 38% of cases. Overall survival was 92%. Conclusions: Tumor subtype, biology, hormonal influence, and lymph node status are all important prognostic factors in malignant melanoma in childhood and adolescence. Compared with adults, children presenting with thicker melanomas and more advanced stage disease generally have more favorable outcomes and a better survival. Plastic surgeons, commonly encountering skin lesion in children, must maintain a high index of suspicion so that early excision and sentinel lymph node biopsy may be promptly offered to patients with melanoma.
Language	English
Publishing date	2019-08-30
Publishing country	United States
Document type	Journal Article
ZDB-ID	2851682-5
ISSN	2169-7574 ; 2169-7574
ISSN (online)	2169-7574
ISSN	2169-7574
DOI	10.1097/GOX.0000000000002338
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Article ; Online: Cutting edge: teaching future surgeons.

Al-Himdani, Sarah / Patel, Lopa

The clinical teacher

2014 Volume 11, Issue 5, Page(s) 397–398

MeSH term(s)	England ; General Surgery/education ; Humans ; Internship and Residency/methods ; Internship and Residency/organization & administration ; Teaching/methods ; Time Factors
Language	English
Publishing date	2014-08
Publishing country	England
Document type	Journal Article
ZDB-ID	2151518-9
ISSN	1743-498X ; 1743-4971
ISSN (online)	1743-498X
ISSN	1743-4971
DOI	10.1111/tct.12152
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Zs.A 6678: Show issues

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Article ; Online: Burns surgery antiseptic preparation: A UK national survey.

Thakkar, Mehul / Wearn, Christopher / Al-Himdani, Sarah / Sack, Anthony / Sen, Sankhya / Estela, Catalina

Burns : journal of the International Society for Burn Injuries

2019 Volume 45, Issue 6, Page(s) 1491–1492

MeSH term(s)	Anti-Infective Agents, Local/therapeutic use ; Burns/surgery ; Chlorhexidine/therapeutic use ; Humans ; Povidone-Iodine/therapeutic use ; Practice Patterns, Physicians' ; Surgical Procedures, Operative/methods ; Surveys and Questionnaires ; United Kingdom ; Wound Infection/prevention & control
Chemical Substances	Anti-Infective Agents, Local ; Povidone-Iodine (85H0HZU99M) ; Chlorhexidine (R4KO0DY52L)
Language	English
Publishing date	2019-06-11
Publishing country	Netherlands
Document type	Letter
ZDB-ID	197308-3
ISSN	1879-1409 ; 0305-4179
ISSN (online)	1879-1409
ISSN	0305-4179
DOI	10.1016/j.burns.2019.05.011
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Zs.A 1250: Show issues

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Article ; Online: Antimicrobial prophylaxis for dog bites in UK plastic surgery units: a nationwide survey.

Al-Himdani, Sarah / Tan, Kian T / Duff, Christopher G

Journal of plastic, reconstructive & aesthetic surgery : JPRAS

2015 Volume 68, Issue 3, Page(s) 428–429

MeSH term(s)	Animals ; Anti-Infective Agents/administration & dosage ; Antibiotic Prophylaxis ; Bites and Stings/drug therapy ; Dogs ; Humans ; Practice Patterns, Physicians'/statistics & numerical data ; United Kingdom ; Wound Infection/prevention & control
Chemical Substances	Anti-Infective Agents
Language	English
Publishing date	2015-03
Publishing country	Netherlands
Document type	Letter
ZDB-ID	2217750-4
ISSN	1878-0539 ; 1748-6815 ; 0007-1226
ISSN (online)	1878-0539
ISSN	1748-6815 ; 0007-1226
DOI	10.1016/j.bjps.2014.10.025
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Article ; Online: The medial sural artery perforator (MSAP) flap: A versatile flap for lower extremity reconstruction.

Al-Himdani, Sarah / Din, Asmat / Wright, Thomas C / Wheble, George / Chapman, Thomas W L / Khan, Umraz

Injury

2020 Volume 51, Issue 4, Page(s) 1077–1085

Abstract: Background: The medial sural artery perforator (MSAP) flap provides a thin, pliable and durable soft tissue reconstruction with adequate pedicle length and low donor morbidity. It is an ideal choice for small-to-moderate defects of the lower extremity, ... ...

Abstract	Background: The medial sural artery perforator (MSAP) flap provides a thin, pliable and durable soft tissue reconstruction with adequate pedicle length and low donor morbidity. It is an ideal choice for small-to-moderate defects of the lower extremity, although it does have limitations. We report our experience of the flap in a three-pronged anatomical, clinical and patient reported outcome-based study. Methods: Cadaveric fresh frozen lower limbs (n = 10) were used for anatomical dissections to assess pertinent and clinically relevant findings. Data relating to MSAP flaps was collected from a prospectively maintained database over a 2-year period. Both clinical data and modified Enneking scores were analysed. Results: Anatomical study: A mean of 2.1 ± 0.99 perforators arose from the medial sural artery, located 11.9 cm ± 2.07 along the line between the popliteal fossa and medial malleolus. The largest perforator was located 13.58 cm ± 2.01 from the popliteal artery. The distance from the dominant perforator to the first branching point within the gastrocnemius was 7.39 ± 1.50 (range 5-9.2 cm). The short saphenous vein was located on average 3.08 cm ± 0.77 from the dominant perforator. Clinical study: Twenty free and nine pedicled MSAPs were included (n = 29). Open lower limb fractures (n = 18, 62%) and infection (n = 10, 35%) were the most common aetiologies. Defects sites included: foot-and-ankle (n = 12, 55%), knee (n = 9, 31%) and anterior leg (n = 4, 14%). Four patients (14%) required SSG to for donor site coverage. Venous congestion was responsible for partial flap necrosis in 6.9%(n = 2) of patients. All wounds were healed at discharge. At 14 months, the mean Enneking score was 72.5%. All patients were ambulant, 96% returned to work and 87% were using pre-operative footwear. Conclusions: The MSAP provides robust foot-and-ankle reconstruction, whilst permitting glide when over the knee. Patient satisfaction and functional outcomes are excellent with careful patient selection. Care should be taken to avoid compression or kinking of the large, thin walled veins as the most commonly observed complication was venous congestion. We advocate MSAP as a first choice flap for small-to-moderate foot, ankle or knee defects.
MeSH term(s)	Adult ; Aged ; Cadaver ; Female ; Free Tissue Flaps/blood supply ; Humans ; Lower Extremity/injuries ; Lower Extremity/surgery ; Male ; Middle Aged ; Patient Satisfaction ; Perforator Flap/blood supply ; Postoperative Complications/etiology ; Reconstructive Surgical Procedures/adverse effects ; Retrospective Studies ; Surgical Wound Dehiscence/etiology ; Young Adult
Language	English
Publishing date	2020-02-12
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	218778-4
ISSN	1879-0267 ; 0020-1383
ISSN (online)	1879-0267
ISSN	0020-1383
DOI	10.1016/j.injury.2020.02.060
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Zs.A 778: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MO 10: Show issues

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Article: The Challenge for Reconstructive Surgeons in the Twenty-First Century: Manufacturing Tissue-Engineered Solutions.

Jessop, Zita M / Al-Himdani, Sarah / Clement, Marc / Whitaker, Iain Stuart

Frontiers in surgery

2015 Volume 2, Page(s) 52

Language	English
Publishing date	2015-10-16
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2773823-1
ISSN	2296-875X
ISSN	2296-875X
DOI	10.3389/fsurg.2015.00052
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Article ; Online: Comparison of Local Recurrence After Simple and Skin-Sparing Mastectomy Performed in Patients with Ductal Carcinoma In Situ.

Timbrell, Simon / Al-Himdani, Sarah / Shaw, Oliver / Tan, Kian / Morris, Julie / Bundred, Nigel

Annals of surgical oncology

2017 Volume 24, Issue 4, Page(s) 1071–1076

Abstract: Background: The incidence of ductal carcinoma in situ (DCIS) is increasing with the use of screening mammography, and approximately 30% of all women diagnosed with DCIS are treated by mastectomy. There is increasing use of a skin-sparing mastectomy (SSM) ...

Abstract	Background: The incidence of ductal carcinoma in situ (DCIS) is increasing with the use of screening mammography, and approximately 30% of all women diagnosed with DCIS are treated by mastectomy. There is increasing use of a skin-sparing mastectomy (SSM) approach to surgically excise DCIS as this facilitates immediate breast reconstruction. The rates of locoregional recurrence (LRR) after simple mastectomy performed for pure DCIS are historically reported as 1%; however, international data suggest that LRR after SSM may be higher. Methods: To determine our rates of LRR and compare the effect of the type of mastectomy performed, we undertook a retrospective review of all patients who underwent a mastectomy for pure DCIS at our institution between 2000 and 2010. Results: In total, 199 patients underwent a mastectomy for pure DCIS (with eight local recurrences), all of which were invasive ductal carcinoma. The recurrences all occurred after SSM, which was associated with a higher 5-year LRR of 5.9% (5/102) compared with 0% in the simple mastectomy group (0/97; p = 0.012), log-rank. Univariate analysis showed the two factors that predicted the risk of recurrence were a young age at mastectomy and close or involved margins. Conclusions: These data highlight the importance of achieving clear margins, especially in young women with estrogen receptor-negative DCIS who have a higher risk of invasive recurrence. Women undergoing a mastectomy for DCIS should be counseled as to the importance of achieving clear margins and the potential increased need for further excision, post-mastectomy radiotherapy and post-reconstruction mammography in order to prevent LRR after SSM.
Language	English
Publishing date	2017-04
Publishing country	United States
Document type	Journal Article
ZDB-ID	1200469-8
ISSN	1534-4681 ; 1068-9265
ISSN (online)	1534-4681
ISSN	1068-9265
DOI	10.1245/s10434-016-5673-6
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