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  1. Article ; Online: Diagnostic validity of premenstrual dysphoric disorder: revisited.

    Naik, Shalini S / Nidhi, Yadav / Kumar, Krishan / Grover, Sandeep

    Frontiers in global women's health

    2023  Volume 4, Page(s) 1181583

    Abstract: The World Health Organization (WHO) and American Psychiatric Association (APA) have recognised premenstrual dysphoric disorder (PMDD) as an independent diagnostic entity, legitimising the distress and socio-occupational impairment experienced by affected ...

    Abstract The World Health Organization (WHO) and American Psychiatric Association (APA) have recognised premenstrual dysphoric disorder (PMDD) as an independent diagnostic entity, legitimising the distress and socio-occupational impairment experienced by affected women. However, the biological validity of this diagnosis remains inexplicit. This illness has also been criticised for a feminist-led, sympathetic reaction to the modern cultural challenges of urban, literate, employed, high-functioning women. This article systematically reviews existing literature on PMDD using the criteria established by Robins and Guze for the validity of a psychiatric diagnosis (clinical description, laboratory study, exclusion of other disorders, follow-up study, and family study). Despite the early recognition of premenstrual syndrome (PMS) in the 1950s, the research has encountered challenges due to two groups of proponents viewing it with psychologising bias and medicalising bias. PMDD is currently understood as the most severe form of PMS, characterised by the presence of psychological features. Recent evidence suggests that PMDD perhaps has neurodevelopmental underpinnings (attention deficit hyperactive disorder, adverse childhood experiences) affecting the fronto-limbic circuit that regulates the emotions. In addition, the affected individuals exhibit an increased sensitivity to gonadal hormonal fluctuations as observed during premenstrual, pregnancy, and perimenopausal phases of life. The prevalence is comparable between high-income countries and low- and middle-income countries (LAMIC), refuting the notion that it mostly affects modern women. Instead, a greater prevalence is observed in LAMIC. Despite the fact that educated women possess knowledge regarding the importance of getting help, there is a prevalent issue of inadequate help-seeking behaviour. This can be attributed to the perception of seeking help as an isolating experience, which is influenced by profound internalised stigma and discrimination in the workplace. Future studies must aim to develop culturally validated assessment tools and more research to understand the life course of the illness, in addition to systematically examining for more biological validators (animal models, genetics, imaging, neurotransmitters).
    Language English
    Publishing date 2023-11-27
    Publishing country Switzerland
    Document type Journal Article ; Review
    ISSN 2673-5059
    ISSN (online) 2673-5059
    DOI 10.3389/fgwh.2023.1181583
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: COVID-19 vaccination prioritization for persons with severe mental illness.

    Jakhar, Jitender / Naik, Shalini S / Prasad, Shiv

    Asian journal of psychiatry

    2021  Volume 64, Page(s) 102792

    MeSH term(s) COVID-19 ; COVID-19 Vaccines ; Humans ; Mental Disorders ; SARS-CoV-2 ; Vaccination
    Chemical Substances COVID-19 Vaccines
    Language English
    Publishing date 2021-07-24
    Publishing country Netherlands
    Document type Letter
    ZDB-ID 2456678-0
    ISSN 1876-2026 ; 1876-2018
    ISSN (online) 1876-2026
    ISSN 1876-2018
    DOI 10.1016/j.ajp.2021.102792
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Global visuospatial processing - a screening tool to predict cognition in schizophrenia.

    Mehta, Urvakhsh Meherwan / Naik, Shalini S / Thirthalli, Jagadisha

    Schizophrenia research

    2021  Volume 228, Page(s) 311–313

    MeSH term(s) Cognition ; Humans ; Neuropsychological Tests ; Schizophrenia/complications ; Schizophrenia/diagnosis ; Space Perception
    Language English
    Publishing date 2021-01-23
    Publishing country Netherlands
    Document type Letter ; Research Support, Non-U.S. Gov't
    ZDB-ID 639422-x
    ISSN 1573-2509 ; 0920-9964
    ISSN (online) 1573-2509
    ISSN 0920-9964
    DOI 10.1016/j.schres.2020.12.039
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Effectiveness of buprenorphine (naloxone) for opioid dependence does not differ across opioid categories: a retrospective cohort study from India.

    Ghosh, Abhishek / Shaktan, Alka / Basu, Debasish / Bn, Subodh / Naik, Shalini S / Mattoo, S K

    Journal of psychoactive drugs

    2023  , Page(s) 1–9

    Abstract: We aimed to examine whether treatment retention, abstinence, and adherence to buprenorphine-naloxone (BNX) differ among individuals with opioid dependence (OD) across three common categories of opioids- heroin, opium, and low-potency pharmaceutical. In a ...

    Abstract We aimed to examine whether treatment retention, abstinence, and adherence to buprenorphine-naloxone (BNX) differ among individuals with opioid dependence (OD) across three common categories of opioids- heroin, opium, and low-potency pharmaceutical. In a retrospective cohort study, we analyzed outpatient treatment records from March 2020 through February 2022. Opioid category was determined by lifetime and current opioid use. We defined treatment retention as weeks of uninterrupted clinic attendance. Abstinence and BNX adherence were calculated by weeks of extra-medical opioid-negative and buprenorphine-positive urine screening from treatment initiation. Four-hundred-thirteen patients were eligible; 406 (98.3%) were included in the final analysis. Two-hundred-ninety (71.4%) patients were dependent on heroin; 66 (16.3%) were natural opioid dependent, and 50 (12.3%) were dependent on low-potency pharmaceutical opioids. BNX effectiveness in treatment retention, abstinence, and adherence did not differ in patients dependent on heroin, natural, and low-potency pharmaceutical opioids. Patients on ≥8 mg daily BNX had better retention and adherence than those on <8 mg daily. Patients from lower socioeconomic status (SES) had higher odds of retention, abstinence, and adherence than those from upper/middle SES. Treatment outcomes on BNX did not differ across opioid categories. However, BNX should be dosed adequately.
    Language English
    Publishing date 2023-06-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 392405-1
    ISSN 2159-9777 ; 0279-1072
    ISSN (online) 2159-9777
    ISSN 0279-1072
    DOI 10.1080/02791072.2023.2225061
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Transdiagnostic investigation into the relationship between mirror neuron system activity, echo-phenomena, and theory of mind in major psychoses.

    Shamanna, Varsha / Mehta, Urvakhsh Meherwan / Naik, Shalini S / Basavaraju, Rakshathi / Thirthalli, Jagadisha

    Asian journal of psychiatry

    2023  Volume 82, Page(s) 103504

    Abstract: The association between social cognition and putative mirror neuron system (MNS)-activity in major psychoses might be contingent upon frontal dysregulation. We used a transdiagnostic ecological approach to enrich a specific behavioral phenotype ( ... ...

    Abstract The association between social cognition and putative mirror neuron system (MNS)-activity in major psychoses might be contingent upon frontal dysregulation. We used a transdiagnostic ecological approach to enrich a specific behavioral phenotype (echophenomena or hyper-imitative states) across clinical diagnoses (mania and schizophrenia) to compare behavioral and physiological markers of social cognition and frontal disinhibition. We examined 114 participants with schizophrenia (N = 53) and mania (N = 61) for the presence and severity of echo-phenomena (echopraxia, incidental, and induced echolalia) using an ecological paradigm to simulate real-life social communication. Symptom severity, frontal release reflexes, and theory of mind performance were also assessed. In a proportion of these participants with (N = 20) and without (N = 20) echo-phenomena, we compared motor resonance (motor evoked potential facilitation during action observation compared to static image viewing) and cortical silent period (CSP) as putative markers of MNS-activity and frontal disinhibition, respectively, using Transcranial Magnetic Stimulation. While the prevalence of echo-phenomena was similar between mania and schizophrenia, incidental echolalia was more severe in mania. Participants with echo-phenomena (compared to those without) had significantly greater motor resonance with singlepulse (not with paired-pulse) stimuli, poorer theory of mind scores, higher frontal release reflexes but similar CSP, and greater symptom severity. None of these parameters significantly differed between participants with mania and schizophrenia. We observed relatively better phenotypic and neurophysiological characterization of major psychoses by categorizing participants based on the presence of echophenomena than clinical diagnoses. Higher putative MNS-activity was associated with poorer theory of mind in a hyper-imitative behavioral state.
    MeSH term(s) Humans ; Mirror Neurons/physiology ; Echolalia ; Mania ; Theory of Mind/physiology ; Psychotic Disorders/diagnostic imaging
    Language English
    Publishing date 2023-02-09
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2456678-0
    ISSN 1876-2026 ; 1876-2018
    ISSN (online) 1876-2026
    ISSN 1876-2018
    DOI 10.1016/j.ajp.2023.103504
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Frequency and Duration of Course of ECT Sessions: An Appraisal of Recent Evidence.

    Thirthalli, Jagadisha / Naik, Shalini S / Kunigiri, Girish

    Indian journal of psychological medicine

    2020  Volume 42, Issue 3, Page(s) 207–218

    Abstract: Aims and method: This paper aims to review the recent literature regarding factors influencing the frequency and number of sessions during a course of electroconvulsive therapy (ECT) for different psychiatric disorders. We systematically reviewed ... ...

    Abstract Aims and method: This paper aims to review the recent literature regarding factors influencing the frequency and number of sessions during a course of electroconvulsive therapy (ECT) for different psychiatric disorders. We systematically reviewed English-language papers of clinical trials of ECT published since the year 2000 in terms of frequency and number of sessions of ECT.
    Results: None of the 30 studies meeting our inclusion criteria were specifically designed to study frequency or number of sessions of ECT. A preliminary inference may be drawn regarding the number of sessions from the information available in these papers. For depression, patients receiving brief-pulse ECT needed fewer sessions than those receiving ultra-brief ECT when these were delivered at 8-times the threshold with unilateral electrode placement or at 2.5-times the threshold with bilateral placement. For schizophrenia, those receiving bifrontal ECT and ECT at 4-times the threshold-level stimulus needed fewer sessions than those receiving bitemporal ECT and 2-times the threshold-level stimulus, respectively. There were no clinical trials of the frequency of ECT sessions.
    Clinical implications: As there is a dearth of studies specifically examining frequency and number of ECT sessions, broad recommendations from professional bodies should continue to guide practice.
    Language English
    Publishing date 2020-04-25
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2622378-8
    ISSN 0975-1564 ; 0253-7176
    ISSN (online) 0975-1564
    ISSN 0253-7176
    DOI 10.4103/IJPSYM.IJPSYM_410_19
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Biomedical data analysis using neuro-fuzzy model with post-feature reduction

    Himansu Das / Bighnaraj Naik / H.S. Behera / Shalini Jaiswal / Priyanka Mahato / Minakhi Rout

    Journal of King Saud University: Computer and Information Sciences, Vol 34, Iss 6, Pp 2540-

    2022  Volume 2550

    Abstract: Now-a-days, a large volume of biomedical data are continuously generated from various biomedical devices and experiments due to the rapid technological advancement in medical science. The effective analysis of these biomedical data such as extracting the ...

    Abstract Now-a-days, a large volume of biomedical data are continuously generated from various biomedical devices and experiments due to the rapid technological advancement in medical science. The effective analysis of these biomedical data such as extracting the significant features biologically and diagnostically is really a challenging task. This paper proposes a Neuro-Fuzzy model with post-feature reduction to analyze these complex biomedical data. The proposed Neuro-Fuzzy approach uses class belongingness fuzzification of input patterns to handle uncertainty issues. However, the complexity of the model increases due to this fuzzy expansion of input patterns. On the other hand, all the expanded fuzzified patterns may not always be significant for model identification. To address this issue, post-feature reduction has been employed on fuzzified patterns to filter out the irrelevant, redundant and noisy features. Unlike pre-feature reduction, this allows all the features to be participated in the fuzzification process and then identify irrelevant features from the fuzzified patterns. Further, this approach allows exploring potential fuzzified features from the strong as well as weak feature set. The effectiveness of this proposed model has been tested and validated with a variety of benchmark biomedical data collected from various domains.
    Keywords Biomedical research ; Classification ; Machine learning ; Dimensionality reduction ; Feature reduction ; Neuro-fuzzy ; Electronic computers. Computer science ; QA75.5-76.95
    Subject code 006
    Language English
    Publishing date 2022-06-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Can yoga practise prevent electro-convulsive therapy induced neurocognitive deficits? - Findings from a pilot randomised controlled trial.

    Sudheer, Nivedita / Kumar, Vijay / Bhide, Shree Raksha / Naik, Shalini S / Baliga, Sachin / Varambally, Shivarama / Thirthalli, Jagadisha / Gangadhar, Bangalore N

    Asian journal of psychiatry

    2022  Volume 76, Page(s) 103244

    Abstract: Despite decades of experience with ECT, no single agent has emerged as a suitable strategy to mitigate the associated neuro-cognitive deficits. In this first of its kind pilot randomised controlled trial, we sought to demonstrate the effect of yoga on ... ...

    Abstract Despite decades of experience with ECT, no single agent has emerged as a suitable strategy to mitigate the associated neuro-cognitive deficits. In this first of its kind pilot randomised controlled trial, we sought to demonstrate the effect of yoga on neurocognitive deficits. We found a favourable effect of Yoga in the domain of verbal fluency, however our study did not reveal significant differences in other cognitive domains. Future studies could look to build on this study while addressing the limitations cited.
    MeSH term(s) Cognition Disorders ; Convulsive Therapy ; Electroconvulsive Therapy ; Humans ; Pilot Projects ; Yoga
    Language English
    Publishing date 2022-08-15
    Publishing country Netherlands
    Document type Journal Article ; Randomized Controlled Trial
    ZDB-ID 2456678-0
    ISSN 1876-2026 ; 1876-2018
    ISSN (online) 1876-2026
    ISSN 1876-2018
    DOI 10.1016/j.ajp.2022.103244
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Yoga therapy for social cognition in schizophrenia: An experimental medicine-based randomized controlled trial.

    Govindaraj, Ramajayam / Naik, Shalini S / Mehta, Urvakhsh M / Sharma, Manjunath / Varambally, Shivarama / Gangadhar, B N

    Asian journal of psychiatry

    2021  Volume 62, Page(s) 102731

    Abstract: Negative symptoms and cognitive deficits are difficult-to-treat symptoms of schizophrenia. In this single blind randomized controlled study, we compared change in social cognitive performance in persons with Schizophrenia (PWS) (as per DSM-5), after 6 ... ...

    Abstract Negative symptoms and cognitive deficits are difficult-to-treat symptoms of schizophrenia. In this single blind randomized controlled study, we compared change in social cognitive performance in persons with Schizophrenia (PWS) (as per DSM-5), after 6 weeks of yoga intervention with a waitlist control group. We also examined changes in putative Mirror Neuron System (MNS) activity measured by Transcranial Magnetic Stimulation (TMS) in a subset of sample (n = 30). 51 PWS stabilized on antipsychotic medication for at least 6 weeks, were assigned to add-on yoga therapy (YT) (n = 26) or waitlist (WL) (n = 25). Subjects in the YT group received add-on yoga therapy (20 sessions in 6 weeks). Both the groups continued their standard treatment and were assessed at baseline and after 6 weeks for social cognition, clinical symptoms and social disability. RM-ANOVA showed significant interaction between time and group for social cognition composite score (SCCS) (F = 42.09 [1,44], P < 0.001); negative symptoms (SANS) (F = 74.91 [1,45], P < 0.001); positive symptoms (SAPS) (F = 16.05 [1,45], P < 0.001) and social disability (GSDS) (F = 29.91 [1,46], P < 0.001). MNS activity had increased after 6 weeks in both groups but not of statistical significance. This study demonstrates that 6 weeks of add-on yoga therapy could improve social cognition in PWS compared to waitlist control subjects. However, the change in social cognition was not associated with a change in the putative MNS-activity. It necessiatates further studies to investigate the mechanistic processes of yoga and replicate these observations in a larger sample.
    MeSH term(s) Biomedical Research ; Cognition ; Humans ; Schizophrenia/therapy ; Single-Blind Method ; Social Cognition ; Treatment Outcome ; Yoga
    Language English
    Publishing date 2021-06-01
    Publishing country Netherlands
    Document type Journal Article ; Randomized Controlled Trial
    ZDB-ID 2456678-0
    ISSN 1876-2026 ; 1876-2018
    ISSN (online) 1876-2026
    ISSN 1876-2018
    DOI 10.1016/j.ajp.2021.102731
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: A chart-based study of theta burst stimulation for depression at a tertiary care center.

    Baliga, Sachin Pradeep / Mehta, Urvakhsh Meherwan / Naik, Shalini S / Thanki, Milind Vijay / Mitra, Sayantanava / Arumugham, Shyam Sundar / Kesavan, Muralidharan / Thirthalli, Jagadisha

    Brain stimulation

    2020  Volume 13, Issue 6, Page(s) 1606–1608

    Language English
    Publishing date 2020-09-26
    Publishing country United States
    Document type Letter
    ZDB-ID 2394410-9
    ISSN 1876-4754 ; 1935-861X
    ISSN (online) 1876-4754
    ISSN 1935-861X
    DOI 10.1016/j.brs.2020.09.015
    Database MEDical Literature Analysis and Retrieval System OnLINE

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