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  1. Article: Three-point traction method for endoscopic submucosal dissection using clip-with-thread and clip-with-silicon bands for large early gastric neoplasms.

    Maruoka, Ryohei / Esaki, Mitsuru / Minoda, Yosuke / Tokunaga, Noriko / Haraguchi, Kazuhiro / Ihara, Eikichi / Ogawa, Yoshihiro

    Endoscopy international open

    2024  Volume 12, Issue 1, Page(s) E57–E58

    Language English
    Publishing date 2024-01-08
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2761052-4
    ISSN 2196-9736 ; 2364-3722
    ISSN (online) 2196-9736
    ISSN 2364-3722
    DOI 10.1055/a-2219-8130
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: [113th Scientific Meeting of the Japanese Society of Internal Medicine: Presidential Lecture: Panel Discussion: Molecular Mechanism of Metabolic Syndrome].

    Ogawa, Yoshihiro

    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine

    2018  Volume 105, Issue 9, Page(s) 1632–1636

    MeSH term(s) Chronic Disease ; Fibrosis ; Humans ; Inflammation/metabolism ; Internal Medicine ; Intracellular Space/metabolism ; Japan ; Metabolic Syndrome/metabolism ; Metabolic Syndrome/pathology ; Societies, Medical
    Language Japanese
    Publishing date 2018-10-28
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 952816-7
    ISSN 1883-2083 ; 0021-5384
    ISSN (online) 1883-2083
    ISSN 0021-5384
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    In stock of ZB MED Cologne/Königswinter

    Zs.B 594: Show issues Location:
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  3. Article ; Online: What is the best modality for diagnosing pancreatic cancer?

    Fujimori, Nao / Minoda, Yosuke / Ogawa, Yoshihiro

    Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society

    2022  Volume 34, Issue 4, Page(s) 744–746

    MeSH term(s) Humans ; Pancreatic Neoplasms/diagnosis ; Pancreatic Neoplasms
    Language English
    Publishing date 2022-03-22
    Publishing country Australia
    Document type Editorial ; Comment
    ZDB-ID 1171589-3
    ISSN 1443-1661 ; 0915-5635
    ISSN (online) 1443-1661
    ISSN 0915-5635
    DOI 10.1111/den.14283
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 3854: Show issues Location:
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  4. Article: Molecular Mechanism of Lifestyle-related Diseases : See Both the Wood and Trees!

    Ogawa, Yoshihiro

    Fukuoka igaku zasshi = Hukuoka acta medica

    2016  Volume 107, Issue 11, Page(s) 191–198

    MeSH term(s) Adipocytes ; Animals ; Fatty Liver ; Humans ; Inflammation ; Life Style ; Macrophages ; Obesity/metabolism
    Language Japanese
    Publishing date 2016
    Publishing country Japan
    Document type Journal Article ; Review ; English Abstract
    ZDB-ID 41251-x
    ISSN 0016-254X
    ISSN 0016-254X
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Structure-based design, biophysical characterization, and biochemical application of the heterodimeric affinity purification tag based on the Schistosoma japonicum glutathione-S-transferase (SjGST) homodimer.

    Du, Yan / Kobashigawa, Yoshihiro / Okazaki, Kyo / Ogawa, Mizuki / Kawaguchi, Tomoyuki / Sato, Takashi / Morioka, Hiroshi

    Journal of biochemistry

    2024  

    Abstract: Schistosoma japonicum glutathione-S-transferase (SjGST), so-called GST-tag, is one of the most widely used protein tags for the purification of recombinant proteins by affinity chromatography. Attachment of SjGST enables the purification of a protein of ... ...

    Abstract Schistosoma japonicum glutathione-S-transferase (SjGST), so-called GST-tag, is one of the most widely used protein tags for the purification of recombinant proteins by affinity chromatography. Attachment of SjGST enables the purification of a protein of interest (POI) using commercially available glutathione-immobilizing resins. Here we produced an SjGST mutant pair that forms heterodimers by adjusting the salt bridge pairs in the homodimer interface of SjGST. A molecular dynamics study confirmed that the SjGST mutant pair did not disrupt the heterodimer formation. The modified SjGST protein pair coexpressed in E. coli was purified by glutathione-immobilized resin. The stability of the heterodimeric form of the SjGST mutant pair was further confirmed by size exclusion chromatography. Surface plasmon resonance measurements unveiled the selective formation of heterodimers within the pair, accompanied by a significant suppression of homodimerization. The heterodimeric SjGST exhibited enzymatic activity in assays employing a commercially available fluorescent substrate. By fusing one member of the heterodimeric SjGST pair with a fluorescent protein and the other with the POI, we were able to conveniently and sensitively detect protein-protein interactions using fluorescence spectroscopy in the pull-down assays. Thus, utilization of the heterodimeric SjGST would be a useful tag for protein science.
    Language English
    Publishing date 2024-03-12
    Publishing country England
    Document type Journal Article
    ZDB-ID 218073-x
    ISSN 1756-2651 ; 0021-924X
    ISSN (online) 1756-2651
    ISSN 0021-924X
    DOI 10.1093/jb/mvae028
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  6. Article ; Online: Two-point fixed pulley-traction method in endoscopic submucosal dissection for early gastric neoplasm.

    Takeuchi, Tsubasa / Esaki, Mitsuru / Minoda, Yosuke / Hata, Yoshitaka / Ogino, Haruei / Ihara, Eikichi / Ogawa, Yoshihiro

    Endoscopy

    2023  Volume 55, Issue S 01, Page(s) E1087–E1088

    Language English
    Publishing date 2023-09-27
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 80120-3
    ISSN 1438-8812 ; 0013-726X
    ISSN (online) 1438-8812
    ISSN 0013-726X
    DOI 10.1055/a-2173-8010
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Walking ability after resection of soft tissue sarcoma of the thigh and the sciatic nerve.

    Isobe, Mizuki / Hakozaki, Michiyuki / Kaneuchi, Yoichi / Ogawa, Itaru / Suzuki, Takeo / Sasaki, Nobuyuki / Kameda, Takuya / Matsumoto, Yoshihiro

    Clinical case reports

    2024  Volume 12, Issue 3, Page(s) e8603

    Abstract: Walking ability may be fairly well maintained after sciatic nerve resection combined with wide resection of soft tissue sarcoma, therefore, surgeons should not hesitate to perform sciatic nerve resection to achieve an adequate surgical margin. ...

    Abstract Walking ability may be fairly well maintained after sciatic nerve resection combined with wide resection of soft tissue sarcoma, therefore, surgeons should not hesitate to perform sciatic nerve resection to achieve an adequate surgical margin.
    Language English
    Publishing date 2024-03-08
    Publishing country England
    Document type Case Reports
    ZDB-ID 2740234-4
    ISSN 2050-0904
    ISSN 2050-0904
    DOI 10.1002/ccr3.8603
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Two Akabane virus glycoprotein Gc domains induce neutralizing antibodies in mice.

    Ogawa, Yohsuke / Eguchi, Masahiro / Shimoji, Yoshihiro

    The Journal of veterinary medical science

    2022  Volume 84, Issue 4, Page(s) 538–542

    Abstract: Akabane virus (AKAV), belonging to the genus Orthobunyavirus and family Peribunyaviridae, causes reproductive and congenital abnormalities in ruminants. Its envelope glycoprotein Gc is a neutralizing antigen, on which at least five distinct antigenic ... ...

    Abstract Akabane virus (AKAV), belonging to the genus Orthobunyavirus and family Peribunyaviridae, causes reproductive and congenital abnormalities in ruminants. Its envelope glycoprotein Gc is a neutralizing antigen, on which at least five distinct antigenic regions have been identified. We attempted to identify the domains using truncated recombinant AKAV Gc proteins expressed in Escherichia coli and monoclonal antibodies (mAbs) with AKAV-neutralizing activity. Dot blot analysis revealed that amino acid positions 1-97 and 189-397 (Gc
    MeSH term(s) Animals ; Antibodies, Monoclonal ; Antibodies, Neutralizing ; Antibodies, Viral ; Bunyaviridae Infections/veterinary ; Glycoproteins ; Mice ; Orthobunyavirus ; Recombinant Proteins ; Viral Envelope Proteins
    Chemical Substances Antibodies, Monoclonal ; Antibodies, Neutralizing ; Antibodies, Viral ; Glycoproteins ; Recombinant Proteins ; Viral Envelope Proteins
    Language English
    Publishing date 2022-02-23
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 1071753-5
    ISSN 1347-7439 ; 0916-7250
    ISSN (online) 1347-7439
    ISSN 0916-7250
    DOI 10.1292/jvms.21-0670
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: HNF1A Mutations and Beta Cell Dysfunction in Diabetes.

    Miyachi, Yasutaka / Miyazawa, Takashi / Ogawa, Yoshihiro

    International journal of molecular sciences

    2022  Volume 23, Issue 6

    Abstract: Understanding the genetic factors of diabetes is essential for addressing the global increase in type 2 diabetes. HNF1A mutations cause a monogenic form of diabetes called maturity-onset diabetes of the young (MODY), and HNF1A single-nucleotide ... ...

    Abstract Understanding the genetic factors of diabetes is essential for addressing the global increase in type 2 diabetes. HNF1A mutations cause a monogenic form of diabetes called maturity-onset diabetes of the young (MODY), and HNF1A single-nucleotide polymorphisms are associated with the development of type 2 diabetes. Numerous studies have been conducted, mainly using genetically modified mice, to explore the molecular basis for the development of diabetes caused by HNF1A mutations, and to reveal the roles of HNF1A in multiple organs, including insulin secretion from pancreatic beta cells, lipid metabolism and protein synthesis in the liver, and urinary glucose reabsorption in the kidneys. Recent studies using human stem cells that mimic MODY have provided new insights into beta cell dysfunction. In this article, we discuss the involvement of HNF1A in beta cell dysfunction by reviewing previous studies using genetically modified mice and recent findings in human stem cell-derived beta cells.
    MeSH term(s) Animals ; Diabetes Mellitus, Type 2/genetics ; Insulin Secretion ; Insulin-Secreting Cells ; Mice ; Mutation
    Language English
    Publishing date 2022-03-16
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms23063222
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Cutaneous Adnexal Adenocarcinoma: Genomic Analysis and Successful HER2-targeted Therapy of Metastatic Disease.

    Hirano-Lotman, Yui / Ishida, Yoshihiro / Endo, Yuichiro / Ogawa, Seishi / Kabashima, Kenji

    Acta dermato-venereologica

    2023  Volume 103, Page(s) adv9399

    MeSH term(s) Humans ; Skin/pathology ; Adenocarcinoma/drug therapy ; Adenocarcinoma/genetics ; Adenocarcinoma/pathology ; Genomics ; Receptor, ErbB-2/genetics
    Chemical Substances Receptor, ErbB-2 (EC 2.7.10.1)
    Language English
    Publishing date 2023-08-16
    Publishing country Sweden
    Document type Journal Article
    ZDB-ID 80007-7
    ISSN 1651-2057 ; 0001-5555
    ISSN (online) 1651-2057
    ISSN 0001-5555
    DOI 10.2340/actadv.v103.9399
    Database MEDical Literature Analysis and Retrieval System OnLINE

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