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  1. Book ; Conference proceedings ; Thesis: Direkte und indirekte Mechanismen der Makrophagenpolarisierung durch Natriumchlorid in der Niere

    Casper, Janis Matthäus / Vietinghoff, Sibylle von

    2021  

    Institution Medizinische Hochschule Hannover
    Event/congress Klinik für Nieren- und Hochdruckerkrankungen
    Author's details vorgelegt von Janis Matthäus Casper ; aus der Klinik für Nieren- und Hochdruckerkrankungen der Medizinischen Hochschule Hannover ; Betreuerin: Prof.'in Dr. med. Sibylle von Vietinghoff
    Language German ; English
    Size 12 Blätter, Blatt 993-1001, 33 Blätter, Illustrationen, Diagramme, 30 cm
    Publishing place Hannover
    Publishing country Germany
    Document type Book ; Conference proceedings ; Thesis
    Thesis / German Habilitation thesis Dissertation, Medizinische Hochschule Hannover, 2021
    Note Text auf Deutsch, Sonderabdruck auf Englisch. ; Enthält 1 Zeitschriftenaufsatz aus "Kidney International", Jg. 94 (2018)
    HBZ-ID HT021061643
    Database Catalogue ZB MED Medicine, Health

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  2. Article ; Online: More than a Marker: Arginase-1 in Kidney Repair.

    von Vietinghoff, Sibylle / Schmitt, Roland

    Journal of the American Society of Nephrology : JASN

    2022  Volume 33, Issue 6, Page(s) 1051–1053

    MeSH term(s) Acute Kidney Injury ; Arginase ; Humans ; Kidney ; Kidney Tubules, Proximal
    Chemical Substances Arginase (EC 3.5.3.1)
    Language English
    Publishing date 2022-05-16
    Publishing country United States
    Document type Editorial ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 1085942-1
    ISSN 1533-3450 ; 1046-6673
    ISSN (online) 1533-3450
    ISSN 1046-6673
    DOI 10.1681/ASN.2022020161
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Letter to the Editor.

    Volkmann, Julia / von Vietinghoff, Sibylle

    Journal of leukocyte biology

    2020  Volume 108, Issue 6, Page(s) 1707

    MeSH term(s) Gingival Crevicular Fluid ; Humans ; Neutrophils ; Periodontitis
    Language English
    Publishing date 2020-08-13
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 605722-6
    ISSN 1938-3673 ; 0741-5400
    ISSN (online) 1938-3673
    ISSN 0741-5400
    DOI 10.1002/JLB.3LT0720-404R
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Book ; Online ; Thesis: Die Rolle von humanen Monozytensubtypen und der CX3CR1-CX3CL1 Interaktion in der Regulation des Endothelphänotyps bei chronischer Niereninsuffizienz

    Roy-Chowdhury, Eva [Verfasser] / Vietinghoff, Sibylle von [Akademischer Betreuer]

    2023  

    Author's details Eva Roy-Chowdhury ; Akademischer Betreuer: Sibylle von Vietinghoff ; Klinik für Nieren- und Hochdruckerkrankungen
    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language German
    Publisher Bibliothek der Medizinischen Hochschule Hannover
    Publishing place Hannover
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

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  5. Article ; Online: Regulation and function of CX3CR1 and its ligand CX3CL1 in kidney disease.

    von Vietinghoff, Sibylle / Kurts, Christian

    Cell and tissue research

    2021  Volume 385, Issue 2, Page(s) 335–344

    Abstract: Attraction, retention, and differentiation of leukocytes to and within the kidney are governed by chemokines. The chemokine CX3CL1 (fractalkine) and its receptor CX3CR1 are exemplary in this regard as they are highly expressed and further upregulated in ... ...

    Abstract Attraction, retention, and differentiation of leukocytes to and within the kidney are governed by chemokines. The chemokine CX3CL1 (fractalkine) and its receptor CX3CR1 are exemplary in this regard as they are highly expressed and further upregulated in a range of kidney diseases. CX3CL1 is chiefly produced by renal endothelium and tubular epithelium, where it promotes leukocyte attraction. Recent data suggest that in addition to established soluble mediators, cellular interactions may enhance CX3CL1 expression. The receptor CX3CR1 is essential in myeloid phagocyte homing to the kidney at homeostasis, after acute cell depletion and in inflammation. CX3CR1 and its ligand are highly regulated in human kidney diseases such as IgA nephritis, systemic lupus erythematosus, and inflammatory conditions such as transplant rejection. A mechanistic role of CX3CR1 has been established in experimental models of nephrotoxic nephritis and renal candidiasis. It is debated in fibrosis. Recent publications demonstrate a role for CX3CR1
    MeSH term(s) Animals ; CX3C Chemokine Receptor 1/immunology ; Chemokine CX3CL1/immunology ; Humans ; Kidney/pathology ; Kidney Diseases/immunology
    Chemical Substances CX3C Chemokine Receptor 1 ; CX3CL1 protein, human ; CX3CR1 protein, human ; Chemokine CX3CL1
    Language English
    Publishing date 2021-05-19
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 125067-x
    ISSN 1432-0878 ; 0302-766X
    ISSN (online) 1432-0878
    ISSN 0302-766X
    DOI 10.1007/s00441-021-03473-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Fate mapping reveals compartment-specific clonal expansion of mononuclear phagocytes during kidney disease.

    Yin, Junping / Mei, Qi / Prinz, Marco / Abdullah, Zeinab / Panzer, Ulf / Li, Jian / von Vietinghoff, Sibylle / Kurts, Christian

    Kidney international

    2023  Volume 104, Issue 3, Page(s) 605–610

    MeSH term(s) Humans ; Phagocytes ; Macrophages ; Kidney Diseases ; Monocytes
    Language English
    Publishing date 2023-06-07
    Publishing country United States
    Document type Letter ; Research Support, Non-U.S. Gov't
    ZDB-ID 120573-0
    ISSN 1523-1755 ; 0085-2538
    ISSN (online) 1523-1755
    ISSN 0085-2538
    DOI 10.1016/j.kint.2023.04.031
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Annexin A1 exerts renoprotective effects in experimental crescentic glomerulonephritis.

    Labes, Robert / Dong, Lei / Mrowka, Ralf / Bachmann, Sebastian / von Vietinghoff, Sibylle / Paliege, Alexander

    Frontiers in physiology

    2022  Volume 13, Page(s) 984362

    Abstract: Non-resolving inflammation plays a critical role during the transition from renal injury towards end-stage renal disease. The glucocorticoid-inducible protein annexin A1 has been shown to function as key regulator in the resolution phase of inflammation, ...

    Abstract Non-resolving inflammation plays a critical role during the transition from renal injury towards end-stage renal disease. The glucocorticoid-inducible protein annexin A1 has been shown to function as key regulator in the resolution phase of inflammation, but its role in immune-mediated crescentic glomerulonephritis has not been studied so far.
    Language English
    Publishing date 2022-10-12
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2564217-0
    ISSN 1664-042X
    ISSN 1664-042X
    DOI 10.3389/fphys.2022.984362
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Book ; Online ; Thesis: NLRP3

    Wildgrube, Susann [Verfasser] / Girndt, Matthias [Gutachter] / Edemir, Bayram [Gutachter] / Vietinghoff, Sibylle von [Gutachter]

    2022  

    Author's details ASC Expression bei Hämodialysepatienten und nierengesunden Bluthochdruckpatienten / Susann Wildgrube ; Gutachter: Matthias Girndt, Bayram Edemir, Sibylle Vietinghoff
    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language German
    Publisher Universitäts- und Landesbibliothek Sachsen-Anhalt
    Publishing place Halle (Saale)
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

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  9. Article: Regulation and function of CX3CR1 and its ligand CX3CL1 in kidney disease

    von Vietinghoff, Sibylle / Kurts, Christian

    Cell and tissue research. 2021 Aug., v. 385, no. 2

    2021  

    Abstract: Attraction, retention, and differentiation of leukocytes to and within the kidney are governed by chemokines. The chemokine CX3CL1 (fractalkine) and its receptor CX3CR1 are exemplary in this regard as they are highly expressed and further upregulated in ... ...

    Abstract Attraction, retention, and differentiation of leukocytes to and within the kidney are governed by chemokines. The chemokine CX3CL1 (fractalkine) and its receptor CX3CR1 are exemplary in this regard as they are highly expressed and further upregulated in a range of kidney diseases. CX3CL1 is chiefly produced by renal endothelium and tubular epithelium, where it promotes leukocyte attraction. Recent data suggest that in addition to established soluble mediators, cellular interactions may enhance CX3CL1 expression. The receptor CX3CR1 is essential in myeloid phagocyte homing to the kidney at homeostasis, after acute cell depletion and in inflammation. CX3CR1 and its ligand are highly regulated in human kidney diseases such as IgA nephritis, systemic lupus erythematosus, and inflammatory conditions such as transplant rejection. A mechanistic role of CX3CR1 has been established in experimental models of nephrotoxic nephritis and renal candidiasis. It is debated in fibrosis. Recent publications demonstrate a role for CX3CR1⁺ myeloid cells in radio-contrast-agent and sepsis-induced kidney damage. Systemically, circulating CX3CR1⁺ monocytes reversibly increase in individuals with renal impairment and correlate with their cardiovascular risk. In this review, we discuss role and regulatory mechanisms of the CX3CL1-CX3CR1 axis in both localized and systemic effects of renal inflammation.
    Keywords candidiasis ; chemokine CX3CL1 ; endothelium ; fibrosis ; graft rejection ; homeostasis ; humans ; inflammation ; kidneys ; ligands ; lupus erythematosus ; monocytes ; nephritis ; nephrotoxicity ; research ; risk
    Language English
    Dates of publication 2021-08
    Size p. 335-344.
    Publishing place Springer Berlin Heidelberg
    Document type Article
    Note Review
    ZDB-ID 125067-x
    ISSN 1432-0878 ; 0302-766X
    ISSN (online) 1432-0878
    ISSN 0302-766X
    DOI 10.1007/s00441-021-03473-0
    Database NAL-Catalogue (AGRICOLA)

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  10. Article ; Online: Inflammation in atherosclerosis: A key role for cytokines.

    von Vietinghoff, Sibylle / Koltsova, Ekaterina K

    Cytokine

    2019  Volume 122, Page(s) 154819

    MeSH term(s) Animals ; Atherosclerosis/immunology ; Atherosclerosis/metabolism ; Atherosclerosis/therapy ; Cytokines/metabolism ; Humans ; Inflammation/immunology ; Inflammation/metabolism
    Chemical Substances Cytokines
    Language English
    Publishing date 2019-08-22
    Publishing country England
    Document type Editorial ; Introductory Journal Article
    ZDB-ID 1018055-2
    ISSN 1096-0023 ; 1043-4666
    ISSN (online) 1096-0023
    ISSN 1043-4666
    DOI 10.1016/j.cyto.2019.154819
    Database MEDical Literature Analysis and Retrieval System OnLINE

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