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  1. Article ; Online: Measurement of the Dependence of the Hadron Production Fraction Ratios f_{s}/f_{u} and f_{d}/f_{u} on B Meson Kinematic Variables in Proton-Proton Collisions at sqrt[s]=13  TeV.

    Tumasyan, A / Adam, W / Andrejkovic, J W / Bergauer, T / Chatterjee, S / Damanakis, K / Dragicevic, M / Escalante Del Valle, A / Hussain, P S / Jeitler, M / Krammer, N / Lechner, L / Liko, D / Mikulec, I / Paulitsch, P / Schieck, J / Schöfbeck, R / Schwarz, D / Sonawane, M /
    Templ, S / Waltenberger, W / Wulz, C-E / Darwish, M R / Janssen, T / Kello, T / Rejeb Sfar, H / Van Mechelen, P / Bols, E S / D'Hondt, J / De Moor, A / Delcourt, M / El Faham, H / Lowette, S / Morton, A / Müller, D / Sahasransu, A R / Tavernier, S / Van Doninck, W / Van Putte, S / Vannerom, D / Clerbaux, B / De Lentdecker, G / Favart, L / Hohov, D / Jaramillo, J / Lee, K / Mahdavikhorrami, M / Makarenko, I / Malara, A / Paredes, S / Pétré, L / Postiau, N / Thomas, L / Vanden Bemden, M / Vander Velde, C / Vanlaer, P / Dobur, D / Knolle, J / Lambrecht, L / Mestdach, G / Rendón, C / Samalan, A / Skovpen, K / Tytgat, M / Van Den Bossche, N / Vermassen, B / Wezenbeek, L / Benecke, A / Bruno, G / Bury, F / Caputo, C / David, P / Delaere, C / Donertas, I S / Giammanco, A / Jaffel, K / Jain, Sa / Lemaitre, V / Mondal, K / Taliercio, A / Tran, T T / Vischia, P / Wertz, S / Alves, G A / Coelho, E / Hensel, C / Moraes, A / Rebello Teles, P / Aldá Júnior, W L / Alves Gallo Pereira, M / Barroso Ferreira Filho, M / Brandao Malbouisson, H / Carvalho, W / Chinellato, J / Da Costa, E M / Da Silveira, G G / De Jesus Damiao, D / Dos Santos Sousa, V / Fonseca De Souza, S / Martins, J / Mora Herrera, C / Mota Amarilo, K / Mundim, L / Nogima, H / Santoro, A / Silva Do Amaral, S M / Sznajder, A / Thiel, M / Vilela Pereira, A / Bernardes, C A / Calligaris, L / Tomei, T R Fernandez Perez / Gregores, E M / Mercadante, P G / Novaes, S F / Padula, Sandra S / Aleksandrov, A / Antchev, G / Hadjiiska, R / Iaydjiev, P / Misheva, M / Rodozov, M / Shopova, M / Sultanov, G / Dimitrov, A / Ivanov, T / Litov, L / Pavlov, B / Petkov, P / Petrov, A / Shumka, E / Thakur, S / Cheng, T / Javaid, T / Mittal, M / Yuan, L / Ahmad, M / Bauer, G / Hu, Z / Lezki, S / Yi, K / Chen, G M / Chen, H S / Chen, M / Iemmi, F / Jiang, C H / Kapoor, A / Liao, H / Liu, Z-A / Milosevic, V / Monti, F / Sharma, R / Tao, J / Thomas-Wilsker, J / Wang, J / Zhang, H / Zhao, J / Agapitos, A / An, Y / Ban, Y / Levin, A / Li, C / Li, Q / Lyu, X / Mao, Y / Qian, S J / Sun, X / Wang, D / Xiao, J / Yang, H / Lu, M / You, Z / Lu, N / Gao, X / Leggat, D / Okawa, H / Zhang, Y / Lin, Z / Lu, C / Xiao, M / Avila, C / Barbosa Trujillo, D A / Cabrera, A / Florez, C / Fraga, J / Mejia Guisao, J / Ramirez, F / Rodriguez, M / Ruiz Alvarez, J D / Giljanovic, D / Godinovic, N / Lelas, D / Puljak, I / Antunovic, Z / Kovac, M / Sculac, T / Brigljevic, V / Chitroda, B K / Ferencek, D / Mishra, S / Roguljic, M / Starodumov, A / Susa, T / Attikis, A / Christoforou, K / Konstantinou, S / Mousa, J / Nicolaou, C / Ptochos, F / Razis, P A / Rykaczewski, H / Saka, H / Stepennov, A / Finger, M / Kveton, A / Ayala, E / Carrera Jarrin, E / Abdelalim, A A / Salama, E / Abdullah Al-Mashad, M / Mahmoud, M A / Bhowmik, S / Dewanjee, R K / Ehataht, K / Kadastik, M / Lange, T / Nandan, S / Nielsen, C / Pata, J / Raidal, M / Tani, L / Veelken, C / Eerola, P / Kirschenmann, H / Osterberg, K / Voutilainen, M / Bharthuar, S / Brücken, E / Garcia, F / Havukainen, J / Kim, M S / Kinnunen, R / Lampén, T / Lassila-Perini, K / Lehti, S / Lindén, T / Lotti, M / Martikainen, L / Myllymäki, M / Rantanen, M M / Siikonen, H / Tuominen, E / Tuominiemi, J / Luukka, P / Petrow, H / Tuuva, T / Amendola, C / Besancon, M / Couderc, F / Dejardin, M / Denegri, D / Faure, J L / Ferri, F / Ganjour, S / Gras, P / Hamel de Monchenault, G / Lohezic, V / Malcles, J / Rander, J / Rosowsky, A / Sahin, M Ö / Savoy-Navarro, A / Simkina, P / Titov, M / Baldenegro Barrera, C / Beaudette, F / Buchot Perraguin, A / Busson, P / Cappati, A / Charlot, C / Damas, F / Davignon, O / Diab, B / Falmagne, G / Fontana Santos Alves, B A / Ghosh, S / Granier de Cassagnac, R / Hakimi, A / Harikrishnan, B / Liu, G / Motta, J / Nguyen, M / Ochando, C / Portales, L / Salerno, R / Sarkar, U / Sauvan, J B / Sirois, Y / Tarabini, A / Vernazza, E / Zabi, A / Zghiche, A / Agram, J-L / Andrea, J / Apparu, D / Bloch, D / Bourgatte, G / Brom, J-M / Chabert, E C / Collard, C / Darej, D / Goerlach, U / Grimault, C / Le Bihan, A-C / Van Hove, P / Beauceron, S / Blancon, B / Boudoul, G / Carle, A / Chanon, N / Choi, J / Contardo, D / Depasse, P / Dozen, C / El Mamouni, H / Fay, J / Gascon, S / Gouzevitch, M / Grenier, G / Ille, B / Laktineh, I B / Lethuillier, M / Mirabito, L / Perries, S / Torterotot, L / Vander Donckt, M / Verdier, P / Viret, S / Lomidze, I / Toriashvili, T / Tsamalaidze, Z / Botta, V / Feld, L / Klein, K / Lipinski, M / Meuser, D / Pauls, A / Röwert, N / Teroerde, M / Diekmann, S / Dodonova, A / Eich, N / Eliseev, D / Erdmann, M / Fackeldey, P / Fasanella, D / Fischer, B / Hebbeker, T / Hoepfner, K / Ivone, F / Lee, M Y / Mastrolorenzo, L / Merschmeyer, M / Meyer, A / Mondal, S / Mukherjee, S / Noll, D / Novak, A / Nowotny, F / Pozdnyakov, A / Rath, Y / Redjeb, W / Rehm, F / Reithler, H / Schmidt, A / Schuler, S C / Sharma, A / Stein, A / Torres Da Silva De Araujo, F / Vigilante, L / Wiedenbeck, S / Zaleski, S / Dziwok, C / Flügge, G / Haj Ahmad, W / Hlushchenko, O / Kress, T / Nowack, A / Pooth, O / Stahl, A / Ziemons, T / Zotz, A / Aarup Petersen, H / Aldaya Martin, M / Alimena, J / Asmuss, P / Baxter, S / Bayatmakou, M / Becerril Gonzalez, H / Behnke, O / Bhattacharya, S / Blekman, F / Borras, K / Brunner, D / Campbell, A / Cardini, A / Cheng, C / Colombina, F / Consuegra Rodríguez, S / Correia Silva, G / De Silva, M / Eckerlin, G / Eckstein, D / Estevez Banos, L I / Filatov, O / Gallo, E / Geiser, A / Giraldi, A / Greau, G / Grohsjean, A / Guglielmi, V / Guthoff, M / Jafari, A / Jomhari, N Z / Kaech, B / Kasemann, M / Kaveh, H / Kleinwort, C / Kogler, R / Komm, M / Krücker, D / Lange, W / Leyva Pernia, D / Lipka, K / Lohmann, W / Mankel, R / Melzer-Pellmann, I-A / Mendizabal Morentin, M / Metwally, J / Meyer, A B / Milella, G / Mormile, M / Mussgiller, A / Nürnberg, A / Otarid, Y / Pérez Adán, D / Ranken, E / Raspereza, A / Ribeiro Lopes, B / Rübenach, J / Saggio, A / Savitskyi, M / Scham, M / Scheurer, V / Schnake, S / Schütze, P / Schwanenberger, C / Shchedrolosiev, M / Sosa Ricardo, R E / Stafford, D / Tonon, N / Van De Klundert, M / Vazzoler, F / Ventura Barroso, A / Walsh, R / Walter, D / Wang, Q / Wen, Y / Wichmann, K / Wiens, L / Wissing, C / Wuchterl, S / Yang, Y / Zimermmane Castro Santos, A / Albrecht, A / Albrecht, S / Antonello, M / Bein, S / Benato, L / Bonanomi, M / Connor, P / De Leo, K / Eich, M / El Morabit, K / Feindt, F / Fröhlich, A / Garbers, C / Garutti, E / Hajheidari, M / Haller, J / Hinzmann, A / Jabusch, H R / Kasieczka, G / Keicher, P / Klanner, R / Korcari, W / Kramer, T / Kutzner, V / Labe, F / Lange, J / Lobanov, A / Matthies, C / Mehta, A / Moureaux, L / Mrowietz, M / Nigamova, A / Nissan, Y / Paasch, A / Pena Rodriguez, K J / Quadfasel, T / Rieger, M / Rieger, O / Savoiu, D / Schindler, J / Schleper, P / Schröder, M / Schwandt, J / Sommerhalder, M / Stadie, H / Steinbrück, G / Tews, A / Wolf, M / Brommer, S / Burkart, M / Butz, E / Chwalek, T / Dierlamm, A / Droll, A / Faltermann, N / Giffels, M / Gosewisch, J O / Gottmann, A / Hartmann, F / Horzela, M / Husemann, U / Klute, M / Koppenhöfer, R / Link, M / Lintuluoto, A / Maier, S / Mitra, S / Müller, Th / Neukum, M / Oh, M / Quast, G / Rabbertz, K / Rauser, J / Shvetsov, I / Simonis, H J / Trevisani, N / Ulrich, R / van der Linden, J / Von Cube, R F / Wassmer, M / Wieland, S / Wolf, R / Wozniewski, S / Wunsch, S / Zuo, X / Anagnostou, G / Assiouras, P / Daskalakis, G / Kyriakis, A / Stakia, A / Diamantopoulou, M / Karasavvas, D / Kontaxakis, P / Manousakis-Katsikakis, A / Panagiotou, A / Papavergou, I / Saoulidou, N / Theofilatos, K / Tziaferi, E / Vellidis, K / Zisopoulos, I / Bakas, G / Chatzistavrou, T / Karapostoli, G / Kousouris, K / Papakrivopoulos, I / Tsipolitis, G / Zacharopoulou, A / Adamidis, K / Bestintzanos, I / Evangelou, I / Foudas, C / Gianneios, P / Kamtsikis, C / Katsoulis, P / Kokkas, P / Kosmoglou Kioseoglou, P G / Manthos, N / Papadopoulos, I / Strologas, J / Csanád, M / Farkas, K / Gadallah, M M A / Lökös, S / Major, P / Mandal, K / Pásztor, G / Rádl, A J / Surányi, O / Veres, G I / Bartók, M / Bencze, G / Hajdu, C / Horvath, D / Sikler, F / Veszpremi, V / Beni, N / Czellar, S / Karancsi, J / Molnar, J / Szillasi, Z / Teyssier, D / Raics, P / Ujvari, B / Zilizi, G / Csorgo, T / Nemes, F / Novak, T / Babbar, J / Bansal, S / Beri, S B / Bhatnagar, V / Chaudhary, G / Chauhan, S / Dhingra, N / Gupta, R / Kaur, A / Kaur, H / Kaur, M / Kumar, S / Kumari, P / Meena, M / Sandeep, K / Sheokand, T / Singh, J B / Singla, A / Ahmed, A / Bhardwaj, A / Chhetri, A / Choudhary, B C / Kumar, A / Naimuddin, M / Ranjan, K / Saumya, S / Baradia, S / Barman, S / Bhowmik, D / Dutta, S / Gomber, B / Maity, M / Palit, P / Saha, G / Sahu, B / Sarkar, S / Behera, P K / Behera, S C / Kalbhor, P / Komaragiri, J R / Kumar, D / Muhammad, A / Panwar, L / Pradhan, R / Pujahari, P R / Saha, N R / Sikdar, A K / Verma, S / Naskar, K / Aziz, T / Das, I / Dugad, S / Kumar, M / Mohanty, G B / Suryadevara, P / Banerjee, S / Guchait, M / Karmakar, S / Majumder, G / Mazumdar, K / Thachayath, A / Bahinipati, S / Das, A K / Kar, C / Mal, P / Mishra, T / Muraleedharan Nair Bindhu, V K / Nayak, A / Saha, P / Swain, S K / Vats, D / Alpana, A / Dube, S / Kansal, B / Laha, A / Pandey, S / Rastogi, A / Sharma, S / Bakhshiansohi, H / Khazaie, E / Zeinali, M / Chenarani, S / Etesami, S M / Khakzad, M / Mohammadi Najafabadi, M / Grunewald, M / Abbrescia, M / Aly, R / Aruta, C / Colaleo, A / Creanza, D / Cristella, L / De Filippis, N / De Palma, M / Di Florio, A / Elmetenawee, W / Errico, F / Fiore, L / Iaselli, G / Maggi, G / Maggi, M / Margjeka, I / Mastrapasqua, V / My, S / Nuzzo, S / Pellecchia, A / Pompili, A / Pugliese, G / Radogna, R / Ramos, D / Ranieri, A / Selvaggi, G / Silvestris, L / Simone, F M / Sözbilir, Ü / Stamerra, A / Venditti, R / Verwilligen, P / Abbiendi, G / Battilana, C / Bonacorsi, D / Borgonovi, L / Brigliadori, L / Campanini, R / Capiluppi, P / Castro, A / Cavallo, F R / Cuffiani, M / Dallavalle, G M / Diotalevi, T / Fabbri, F / Fanfani, A / Giacomelli, P / Giommi, L / Grandi, C / Guiducci, L / Lo Meo, S / Lunerti, L / Marcellini, S / Masetti, G / Navarria, F L / Perrotta, A / Primavera, F / Rossi, A M / Rovelli, T / Siroli, G P / Costa, S / Di Mattia, A / Potenza, R / Tricomi, A / Tuve, C / Barbagli, G / Bardelli, G / Camaiani, B / Cassese, A / Ceccarelli, R / Ciulli, V / Civinini, C / D'Alessandro, R / Focardi, E / Latino, G / Lenzi, P / Lizzo, M / Meschini, M / Paoletti, S / Sguazzoni, G / Viliani, L / Benussi, L / Bianco, S / Meola, S / Piccolo, D / Bozzo, M / Chatagnon, P / Ferro, F / Robutti, E / Tosi, S / Benaglia, A / Boldrini, G / Brivio, F / Cetorelli, F / De Guio, F / Dinardo, M E / Dini, P / Gennai, S / Ghezzi, A / Govoni, P / Guzzi, L / Lucchini, M T / Malberti, M / Malvezzi, S / Massironi, A / Menasce, D / Moroni, L / Paganoni, M / Pedrini, D / Pinolini, B S / Ragazzi, S / Redaelli, N / Tabarelli de Fatis, T / Zuolo, D / Buontempo, S / Carnevali, F / Cavallo, N / De Iorio, A / Fabozzi, F / Iorio, A O M / Lista, L / Paolucci, P / Rossi, B / Sciacca, C / Azzi, P / Bacchetta, N / Bisello, D / Bortignon, P / Bragagnolo, A / Carlin, R / Checchia, P / Dorigo, T / Gasparini, F / Gasparini, U / Grosso, G / Gulmini, M / Layer, L / Lusiani, E / Margoni, M / Meneguzzo, A T / Pazzini, J / Ronchese, P / Rossin, R / Simonetto, F / Strong, G / Tosi, M / Yarar, H / Zanetti, M / Zotto, P / Zucchetta, A / Abu Zeid, S / Aimè, C / Braghieri, A / Calzaferri, S / Fiorina, D / Montagna, P / Re, V / Riccardi, C / Salvini, P / Vai, I / Vitulo, P / Asenov, P / Bilei, G M / Ciangottini, D / Fanò, L / Magherini, M / Mantovani, G / Mariani, V / Menichelli, M / Moscatelli, F / Piccinelli, A / Presilla, M / Rossi, A / Santocchia, A / Spiga, D / Tedeschi, T / Azzurri, P / Bagliesi, G / Bertacchi, V / Bhattacharya, R / Bianchini, L / Boccali, T / Bossini, E / Bruschini, D / Castaldi, R / Ciocci, M A / D'Amante, V / Dell'Orso, R / Donato, S / Giassi, A / Ligabue, F / Matos Figueiredo, D / Messineo, A / Musich, M / Palla, F / Parolia, S / Ramirez-Sanchez, G / Rizzi, A / Rolandi, G / Roy Chowdhury, S / Sarkar, T / Scribano, A / Spagnolo, P / Tenchini, R / Tonelli, G / Turini, N / Venturi, A / Verdini, P G / Barria, P / Campana, M / Cavallari, F / Del Re, D / Di Marco, E / Diemoz, M / Longo, E / Meridiani, P / Organtini, G / Pandolfi, F / Paramatti, R / Quaranta, C / Rahatlou, S / Rovelli, C / Santanastasio, F / Soffi, L / Tramontano, R / Amapane, N / Arcidiacono, R / Argiro, S / Arneodo, M / Bartosik, N / Bellan, R / Bellora, A / Biino, C / Cartiglia, N / Costa, M / Covarelli, R / Demaria, N / Grippo, M / Kiani, B / Legger, F / Mariotti, C / Maselli, S / Mecca, A / Migliore, E / Monteno, M / Mulargia, R / Obertino, M M / Ortona, G / Pacher, L / Pastrone, N / Pelliccioni, M / Ruspa, M / Shchelina, K / Siviero, F / Sola, V / Solano, A / Soldi, D / Staiano, A / Tornago, M / Trocino, D / Umoret, G / Vagnerini, A / Vlasov, E / Belforte, S / Candelise, V / Casarsa, M / Cossutti, F / Della Ricca, G / Sorrentino, G / Dogra, S / Huh, C / Kim, B / Kim, D H / Kim, G N / Kim, J / Lee, J / Lee, S W / Moon, C S / Oh, Y D / Pak, S I / Ryu, M S / Sekmen, S / Yang, Y C / Kim, H / Moon, D H / Asilar, E / Kim, T J / Park, J / Choi, S / Han, S / Hong, B / Lee, K S / Lim, J / Park, S K / Yoo, J / Goh, J / Kim, H S / Kim, Y / Lee, S / Almond, J / Bhyun, J H / Jeon, S / Kim, J S / Ko, S / Kwon, H / Lee, H / Oh, B H / Oh, S B / Seo, H / Yang, U K / Yoon, I / Jang, W / Kang, D Y / Kang, Y / Kim, D / Kim, S / Ko, B / Lee, J S H / Lee, Y / Merlin, J A / Park, I C / Roh, Y / Song, D / Watson, I J / Yang, S / Ha, S / Yoo, H D / Choi, M / Kim, M R / Yu, I / Beyrouthy, T / Maghrbi, Y / Dreimanis, K / Pikurs, G / Potrebko, A / Seidel, M / Veckalns, V / Ambrozas, M / Carvalho Antunes De Oliveira, A / Juodagalvis, A / Rinkevicius, A / Tamulaitis, G / Bin Norjoharuddeen, N / Hoh, S Y / Yusuff, I / Zolkapli, Z / Benitez, J F / Castaneda Hernandez, A / Encinas Acosta, H A / Gallegos Maríñez, L G / León Coello, M / Murillo Quijada, J A / Sehrawat, A / Valencia Palomo, L / Ayala, G / Castilla-Valdez, H / Heredia-De La Cruz, I / Lopez-Fernandez, R / Mondragon Herrera, C A / Perez Navarro, D A / Sánchez Hernández, A / Oropeza Barrera, C / Vazquez Valencia, F / Pedraza, I / Salazar Ibarguen, H A / Uribe Estrada, C / Bubanja, I / Mijuskovic, J / Raicevic, N / Ahmad, A / Asghar, M I / Awais, A / Awan, M I M / Gul, M / Hoorani, H R / Khan, W A / Avati, V / Grzanka, L / Malawski, M / Bialkowska, H / Bluj, M / Boimska, B / Górski, M / Kazana, M / Szleper, M / Zalewski, P / Bunkowski, K / Doroba, K / Kalinowski, A / Konecki, M / Krolikowski, J / Araujo, M / Bargassa, P / Bastos, D / Boletti, A / Faccioli, P / Gallinaro, M / Hollar, J / Leonardo, N / Niknejad, T / Pisano, M / Seixas, J / Varela, J / Adzic, P / Dordevic, M / Milenovic, P / Milosevic, J / Aguilar-Benitez, M / Alcaraz Maestre, J / Barrio Luna, M / Bedoya, Cristina F / Cepeda, M / Cerrada, M / Colino, N / De La Cruz, B / Delgado Peris, A / Fernández Del Val, D / Fernández Ramos, J P / Flix, J / Fouz, M C / Gonzalez Lopez, O / Goy Lopez, S / Hernandez, J M / Josa, M I / León Holgado, J / Moran, D / Perez Dengra, C / Pérez-Calero Yzquierdo, A / Puerta Pelayo, J / Redondo, I / Redondo Ferrero, D D / Romero, L / Sánchez Navas, S / Sastre, J / Urda Gómez, L / Vazquez Escobar, J / Willmott, C / de Trocóniz, J F / Alvarez Gonzalez, B / Cuevas, J / Fernandez Menendez, J / Folgueras, S / Gonzalez Caballero, I / González Fernández, J R / Palencia Cortezon, E / Ramón Álvarez, C / Rodríguez Bouza, V / Soto Rodríguez, A / Trapote, A / Vico Villalba, C / Brochero Cifuentes, J A / Cabrillo, I J / Calderon, A / Duarte Campderros, J / Fernandez, M / Fernandez Madrazo, C / García Alonso, A / Gomez, G / Lasaosa García, C / Martinez Rivero, C / Martinez Ruiz Del Arbol, P / Matorras, F / Matorras Cuevas, P / Piedra Gomez, J / Prieels, C / Scodellaro, L / Vila, I / Vizan Garcia, J M / Jayananda, M K / Kailasapathy, B / Sonnadara, D U J / Wickramarathna, D D C / Dharmaratna, W G D / Liyanage, K / Perera, N / Wickramage, N / Abbaneo, D / Auffray, E / Auzinger, G / Baechler, J / Baillon, P / Barney, D / Bendavid, J / Bermúdez Martínez, A / Bianco, M / Bilin, B / Bin Anuar, A A / Bocci, A / Brondolin, E / Caillol, C / Camporesi, T / Cerminara, G / Chernyavskaya, N / Chhibra, S S / Choudhury, S / Cipriani, M / d'Enterria, D / Dabrowski, A / David, A / De Roeck, A / Defranchis, M M / Deile, M / Dobson, M / Dünser, M / Dupont, N / Fallavollita, F / Florent, A / Forthomme, L / Franzoni, G / Funk, W / Giani, S / Gigi, D / Gill, K / Glege, F / Gouskos, L / Govorkova, E / Haranko, M / Hegeman, J / Innocente, V / James, T / Janot, P / Kaspar, J / Kieseler, J / Kratochwil, N / Laurila, S / Lecoq, P / Leutgeb, E / Lourenço, C / Maier, B / Malgeri, L / Mannelli, M / Marini, A C / Meijers, F / Mersi, S / Meschi, E / Moortgat, F / Mulders, M / Orfanelli, S / Orsini, L / Pantaleo, F / Perez, E / Peruzzi, M / Petrilli, A / Petrucciani, G / Pfeiffer, A / Pierini, M / Piparo, D / Pitt, M / Qu, H / Quast, T / Rabady, D / Racz, A / Reales Gutiérrez, G / Rovere, M / Sakulin, H / Salfeld-Nebgen, J / Scarfi, S / Selvaggi, M / Silva, P / Sphicas, P / Stahl Leiton, A G / Summers, S / Tatar, K / Treille, D / Tropea, P / Tsirou, A / Wanczyk, J / Wozniak, K A / Zeuner, W D / Caminada, L / Ebrahimi, A / Erdmann, W / Horisberger, R / Ingram, Q / Kaestli, H C / Kotlinski, D / Lange, C / Missiroli, M / Noehte, L / Rohe, T / Aarrestad, T K / Androsov, K / Backhaus, M / Calandri, A / Datta, K / De Cosa, A / Dissertori, G / Dittmar, M / Donegà, M / Eble, F / Galli, M / Gedia, K / Glessgen, F / Gómez Espinosa, T A / Grab, C / Hits, D / Lustermann, W / Lyon, A-M / Manzoni, R A / Marchese, L / Martin Perez, C / Mascellani, A / Nessi-Tedaldi, F / Niedziela, J / Pauss, F / Perovic, V / Pigazzini, S / Ratti, M G / Reichmann, M / Reissel, C / 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Spiegel, L / Stoynev, S / Strait, J / Taylor, L / Tkaczyk, S / Tran, N V / Uplegger, L / Vaandering, E W / Zoi, I / Avery, P / Bourilkov, D / Cadamuro, L / Chang, P / Cherepanov, V / Field, R D / Koenig, E / Kolosova, M / Konigsberg, J / Korytov, A / Kuznetsova, E / Lo, K H / Matchev, K / Menendez, N / Mitselmakher, G / Muthirakalayil Madhu, A / Rawal, N / Rosenzweig, D / Rosenzweig, S / Shi, K / Wu, Z / Adams, T / Askew, A / Bower, N / Habibullah, R / Hagopian, V / Kolberg, T / Martinez, G / Prosper, H / Viazlo, O / Wulansatiti, M / Yohay, R / Zhang, J / Baarmand, M M / Butalla, S / Elkafrawy, T / Hohlmann, M / Kumar Verma, R / Rahmani, M / Yumiceva, F / Adams, M R / Cavanaugh, R / Dittmer, S / Evdokimov, O / Gerber, C E / Hofman, D J / Lemos, D S / Merrit, A H / Mills, C / Oh, G / Roy, T / Rudrabhatla, S / Tonjes, M B / Varelas, N / Wang, X / Ye, Z / Alhusseini, M / Dilsiz, K / Emediato, L / Karaman, G / Köseyan, O K / Merlo, J-P / Mestvirishvili, A / Nachtman, J / Neogi, O / Ogul, H / Onel, Y / Penzo, A / Snyder, C / Tiras, E / Amram, O / Blumenfeld, B / Corcodilos, L / Davis, J / Gritsan, A V / Kyriacou, S / Maksimovic, P / Roskes, J / Sekhar, S / Swartz, M / Vámi, T Á / Abreu, A / Alcerro Alcerro, L F / Anguiano, J / Baringer, P / Bean, A / Flowers, Z / King, J / Krintiras, G / Lazarovits, M / Le Mahieu, C / Lindsey, C / Marquez, J / Minafra, N / Murray, M / Nickel, M / Rogan, C / Royon, C / Salvatico, R / Sanders, S / Smith, C / Wilson, G / Allmond, B / Duric, S / Ivanov, A / Kaadze, K / Kalogeropoulos, A / Maravin, Y / Mitchell, T / Modak, A / Nam, K / Roy, D / Rebassoo, F / Wright, D / Adams, E / Baden, A / Baron, O / Belloni, A / Bethani, A / Eno, S C / Hadley, N J / Jabeen, S / Kellogg, R G / Koeth, T / Lai, Y / Lascio, S / Mignerey, A C / Nabili, S / Palmer, C / Papageorgakis, C / Wang, L / Wong, K / Busza, W / Cali, I A / Chen, Y / D'Alfonso, M / Eysermans, J / Freer, C / Gomez-Ceballos, G / Goncharov, M / Harris, P / Hu, M / Kovalskyi, D / Krupa, J / 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/ Liu, Y / Odell, N / Schmitt, M H / Velasco, M / Band, R / Bucci, R / Cremonesi, M / Das, A / Goldouzian, R / Hildreth, M / Hurtado Anampa, K / Jessop, C / Lannon, K / Lawrence, J / Loukas, N / Lutton, L / Mariano, J / Marinelli, N / Mcalister, I / McCauley, T / Mcgrady, C / Mohrman, K / Moore, C / Musienko, Y / Ruchti, R / Townsend, A / Wayne, M / Yockey, H / Zarucki, M / Zygala, L / Bylsma, B / Carrigan, M / Durkin, L S / Hill, C / Joyce, M / Lesauvage, A / Nunez Ornelas, M / Wei, K / Winer, B L / Yates, B R / Addesa, F M / Das, P / Dezoort, G / Elmer, P / Frankenthal, A / Greenberg, B / Haubrich, N / Higginbotham, S / Kopp, G / Kwan, S / Lange, D / Loeliger, A / Marlow, D / Ojalvo, I / Olsen, J / Stickland, D / Tully, C / Bakshi, A S / Barnes, V E / Chawla, R / Das, S / Gutay, L / Jones, M / Jung, A W / Kondratyev, D / Koshy, A M / Liu, M / Negro, G / Neumeister, N / Paspalaki, G / Piperov, S / Purohit, A / Schulte, J F / Stojanovic, M / Thieman, J / Virdi, A K / Wang, F / Xiao, R 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A / Ivanov, Y / Kachanov, V / Kardapoltsev, L / Karjavine, V / Karneyeu, A / Kim, V / Kirakosyan, M / Kirpichnikov, D / Kirsanov, M / Klyukhin, V / Kodolova, O / Konstantinov, D / Korenkov, V / Kozyrev, A / Krasnikov, N / Lanev, A / Levchenko, P / Litomin, A / Lychkovskaya, N / Makarenko, V / Malakhov, A / Matveev, V / Murzin, V / Nikitenko, A / Obraztsov, S / Ovtin, I / Palichik, V / Perelygin, V / Petrushanko, S / Polikarpov, S / Popov, V / Radchenko, O / Savina, M / Savrin, V / Selivanova, D / Shalaev, V / Shmatov, S / Shulha, S / Skovpen, Y / Slabospitskii, S / Smirnov, V / Snigirev, A / Sosnov, D / Sulimov, V / Tcherniaev, E / Terkulov, A / Teryaev, O / Tlisova, I / Toropin, A / Uvarov, L / Uzunian, A / Vorobyev, A / Voytishin, N / Yuldashev, B S / Zarubin, A / Zhizhin, I / Zhokin, A

    Physical review letters

    2023  Volume 131, Issue 12, Page(s) 121901

    Abstract: ... to B^{+} meson production fractions, f_{d}/f_{u}, is also measured, for the first time in proton-proton ...

    Abstract The dependence of the ratio between the B_{s}^{0} and B^{+} hadron production fractions, f_{s}/f_{u}, on the transverse momentum (p_{T}) and rapidity of the B mesons is studied using the decay channels B_{s}^{0}→J/ψϕ and B^{+}→J/ψK^{+}. The analysis uses a data sample of proton-proton collisions at a center-of-mass energy of 13 TeV, collected by the CMS experiment in 2018 and corresponding to an integrated luminosity of 61.6  fb^{-1}. The f_{s}/f_{u} ratio is observed to depend on the B p_{T} and to be consistent with becoming asymptotically constant at large p_{T}. No rapidity dependence is observed. The ratio of the B^{0} to B^{+} meson production fractions, f_{d}/f_{u}, is also measured, for the first time in proton-proton collisions, using the B^{0}→J/ψK^{*0} decay channel. The result is found to be within 1 standard deviation of unity and independent of p_{T} and rapidity, as expected from isospin invariance.
    Language English
    Publishing date 2023-10-06
    Publishing country United States
    Document type Journal Article
    ZDB-ID 208853-8
    ISSN 1079-7114 ; 0031-9007
    ISSN (online) 1079-7114
    ISSN 0031-9007
    DOI 10.1103/PhysRevLett.131.121901
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: First expert elicitation of knowledge on drivers of emergence of influenza D in Europe.

    Saegerman, Claude / Bianchini, Juana / Snoeck, Chantal J / Moreno, Ana / Chiapponi, Chiara / Zohari, Siamak / Ducatez, Mariette F

    Transboundary and emerging diseases

    2020  Volume 68, Issue 6, Page(s) 3349–3359

    Abstract: The influenza D virus (IDV) was first identified and characterized in 2011. Considering the virus' ...

    Abstract The influenza D virus (IDV) was first identified and characterized in 2011. Considering the virus' zoonotic potential, its genome nature (segmented RNA virus), its worldwide circulation in livestock and its role in bovine respiratory disease, an increased interest is given to IDV. However, few data are available on drivers of emergence of IDV. We first listed fifty possible drivers of emergence of IDV in ruminants and swine. As recently carried out for COVID-19 in pets (Transboundary and Emerging Diseases, 2020), a scoring system was developed per driver and scientific experts (N = 28) were elicited to (a) allocate a score to each driver, (b) weight the drivers' scores within each domain and (c) weight the different domains among themselves. An overall weighted score was calculated per driver, and drivers were ranked in decreasing order. Drivers with comparable likelihoods to play a role in the emergence of IDV in ruminants and swine in Europe were grouped using a regression tree analysis. Finally, the robustness of the expert elicitation was verified. Eight drivers were ranked with the highest probability to play a key role in the emergence of IDV: current species specificity of the causing agent of the disease; influence of (il)legal movements of live animals (ruminants, swine) from neighbouring/European Union member states and from third countries for the disease to (re-)emerge in a given country; detection of emergence; current knowledge of the pathogen; vaccine availability; animal density; and transport vehicles of live animals. As there is still limited scientific knowledge on the topic, expert elicitation of knowledge and multi-criteria decision analysis, in addition to clustering and sensitivity analyses, are very important to prioritize future studies, starting from the top eight drivers. The present methodology could be applied to other emerging animal diseases.
    MeSH term(s) Animals ; COVID-19/veterinary ; Cattle ; Europe/epidemiology ; Humans ; Influenza, Human ; Orthomyxoviridae Infections/epidemiology ; Orthomyxoviridae Infections/prevention & control ; Orthomyxoviridae Infections/veterinary ; SARS-CoV-2 ; Swine ; Swine Diseases/epidemiology ; Swine Diseases/prevention & control
    Language English
    Publishing date 2020-12-14
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2414822-2
    ISSN 1865-1682 ; 1865-1674
    ISSN (online) 1865-1682
    ISSN 1865-1674
    DOI 10.1111/tbed.13938
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: First expert elicitation of knowledge on drivers of emergence of influenza D in Europe

    Saegerman, Claude / Bianchini, Juana / Snoeck, Chantal J. / Moreno, Ana / Chiapponi, Chiara / Zohari, Siamak / Ducatez, Mariette F.

    Transboundary and emerging diseases. 2021 Nov., v. 68, no. 6

    2021  

    Abstract: The influenza D virus (IDV) was first identified and characterized in 2011. Considering the virus ...

    Abstract The influenza D virus (IDV) was first identified and characterized in 2011. Considering the virus’ zoonotic potential, its genome nature (segmented RNA virus), its worldwide circulation in livestock and its role in bovine respiratory disease, an increased interest is given to IDV. However, few data are available on drivers of emergence of IDV. We first listed fifty possible drivers of emergence of IDV in ruminants and swine. As recently carried out for COVID‐19 in pets (Transboundary and Emerging Diseases, 2020), a scoring system was developed per driver and scientific experts (N = 28) were elicited to (a) allocate a score to each driver, (b) weight the drivers’ scores within each domain and (c) weight the different domains among themselves. An overall weighted score was calculated per driver, and drivers were ranked in decreasing order. Drivers with comparable likelihoods to play a role in the emergence of IDV in ruminants and swine in Europe were grouped using a regression tree analysis. Finally, the robustness of the expert elicitation was verified. Eight drivers were ranked with the highest probability to play a key role in the emergence of IDV: current species specificity of the causing agent of the disease; influence of (il)legal movements of live animals (ruminants, swine) from neighbouring/European Union member states and from third countries for the disease to (re‐)emerge in a given country; detection of emergence; current knowledge of the pathogen; vaccine availability; animal density; and transport vehicles of live animals. As there is still limited scientific knowledge on the topic, expert elicitation of knowledge and multi‐criteria decision analysis, in addition to clustering and sensitivity analyses, are very important to prioritize future studies, starting from the top eight drivers. The present methodology could be applied to other emerging animal diseases.
    Keywords COVID-19 infection ; European Union ; RNA viruses ; animal density ; bovine respiratory disease ; expert opinion ; genome ; influenza ; multi-criteria decision making ; pathogens ; probability ; regression analysis ; swine ; vaccines ; viruses ; zoonoses ; Europe
    Language English
    Dates of publication 2021-11
    Size p. 3349-3359.
    Publishing place John Wiley & Sons, Ltd
    Document type Article
    Note JOURNAL ARTICLE
    ZDB-ID 2414822-2
    ISSN 1865-1682 ; 1865-1674
    ISSN (online) 1865-1682
    ISSN 1865-1674
    DOI 10.1111/tbed.13938
    Database NAL-Catalogue (AGRICOLA)

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  4. Article ; Online: Retinoic acid prevents immunogenicity of milk lipocalin Bos d 5 through binding to its immunodominant T-cell epitope.

    Hufnagl, Karin / Ghosh, Debajyoti / Wagner, Stefanie / Fiocchi, Alessandro / Dahdah, Lamia / Bianchini, Rodolfo / Braun, Nina / Steinborn, Ralf / Hofer, Martin / Blaschitz, Marion / Roth, Georg A / Hofstetter, Gerlinde / Roth-Walter, Franziska / Pacios, Luis F / Jensen-Jarolim, Erika

    Scientific reports

    2018  Volume 8, Issue 1, Page(s) 1598

    Abstract: The major cow's milk allergen Bos d 5 belongs to the lipocalin protein family ... with an intramolecular pocket for hydrophobic ligands. We investigated whether Bos d 5 when loaded with the active ... to the unloaded state. By in silico docking an affinity energy of -7.8 kcal/mol was calculated for RA into Bos d 5 ...

    Abstract The major cow's milk allergen Bos d 5 belongs to the lipocalin protein family, with an intramolecular pocket for hydrophobic ligands. We investigated whether Bos d 5 when loaded with the active vitamin A metabolite retinoic acid (RA), would elicit differential immune responses compared to the unloaded state. By in silico docking an affinity energy of -7.8 kcal/mol was calculated for RA into Bos d 5. Loading of RA to Bos d 5 could be achieved in vitro, as demonstrated by ANS displacement assay, but had no effect on serum IgE binding in tolerant or challenge-positive milk allergic children. Bioinformatic analysis revealed that RA binds to the immunodominant T-cell epitope region of Bos d 5. In accordance, Bos d 5 significantly suppressed the CD3+ CD4+ cell numbers, proliferative response and IL-10, IL-13 and IFN-γ secretion from stimulated human PBMCs only when complexed with RA. This phenomenon was neither associated with apoptosis of T-cells nor with the activation of Foxp3+ T-cells, but correlated likely with enhanced stability to lysosomal digestion due to a predicted overlap of Cathepsin S cleavage sites with the RA binding site. Taken together, proper loading of Bos d 5 with RA may suppress its immunogenicity and prevent its allergenicity.
    MeSH term(s) Allergens/immunology ; Allergens/metabolism ; Animals ; Cattle ; Cell Proliferation/drug effects ; Epitopes, T-Lymphocyte/metabolism ; Humans ; Immunoglobulin E/metabolism ; Immunologic Factors/metabolism ; Interferon-gamma/metabolism ; Interleukin-10/metabolism ; Interleukin-13/metabolism ; Leukocytes, Mononuclear/immunology ; Lipocalins/immunology ; Lipocalins/metabolism ; Lysosomes/metabolism ; Molecular Docking Simulation ; Protein Binding ; Proteolysis ; Tretinoin/metabolism
    Chemical Substances Allergens ; Bos d 5 allergen, Bos taurus ; Epitopes, T-Lymphocyte ; IL10 protein, human ; Immunologic Factors ; Interleukin-13 ; Lipocalins ; Interleukin-10 (130068-27-8) ; Immunoglobulin E (37341-29-0) ; Tretinoin (5688UTC01R) ; Interferon-gamma (82115-62-6)
    Language English
    Publishing date 2018-01-25
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-018-19883-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: D-Ring-Modified Analogues of Luotonin A with Reduced Planarity

    Abdulrahman I. Almansour / Raju Suresh Kumar / Natarajan Arumugam / Giulia Bianchini / J. Carlos Menéndez / Faruq Mohammad / Kotresha Dupadahalli / Mohammad Altaf

    BioMed Research International, Vol

    Design, Synthesis, and Evaluation of Their Topoisomerase Inhibition-Associated Cytotoxicity

    2019  Volume 2019

    Abstract: A- and D-ring-modified luotonin-inspired heterocycles have been synthesized and were evaluated ...

    Abstract A- and D-ring-modified luotonin-inspired heterocycles have been synthesized and were evaluated for their activity against the viability of four cancer cell lines in vitro, namely, MCF7, HCT116, JURKAT, and NCI-H460. The analysis of results indicated that two of the synthesized derivatives displayed good inhibition against the growth of the human colon cancer HCT116 cell line, with potencies lower than but in the same order of magnitude as camptothecin (CPT). These two luotonin analogues also showed an activity similar to that of the highly potent alkaloid CPT as inhibitors of topoisomerase I and also inhibited topoisomerase II. These results show that complete planarity is not a strict requirement for topoisomerase inhibition by luotonin-related compounds, paving the way to the design of analogues with improved solubility.
    Keywords Medicine ; R
    Subject code 616
    Language English
    Publishing date 2019-01-01T00:00:00Z
    Publisher Hindawi Limited
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Réflexions sur la formalisation, en tant que système, d’une transcription des formes des Langues des Signes

    Boutet Dominique / Bianchini Claudia S. / Doan Patrick / Chèvrefils-Desbiolles Léa / Thomas Chloé / Rébulard Morgane / Contesse Adrien / Danet Claire / Dauphin Jean-François / Réguer Mathieu

    SHS Web of Conferences, Vol 78, p

    l’approche Typannot

    2020  Volume 11001

    Abstract: ... et de comprendre les raisons (parmi lesquelles centration sur les mains et utilisation d’un cadre de référence ... selon des degrés de liberté, en fonction d’amplitudes particulières et à travers une série de cadres de référence ... aux traits (caractères), rassemblés dans un niveau de glyphes composés. La facilité d’utilisation de Typannot ...

    Abstract Transcrire les langues des signes (LS) nécessite de prendre en considération leur nature gestuelle et de comprendre les raisons (parmi lesquelles centration sur les mains et utilisation d’un cadre de référence égocentré) pour lesquelles des systèmes typographiques (HamNoSys, SignWriting) ont échoué à s’imposer comme outil de transcription. La gestualité met en mouvement tous les segments du membre supérieur selon des degrés de liberté, en fonction d’amplitudes particulières et à travers une série de cadres de référence intrinsèque centrée sur chaque segment. Typannot, le système typographique présenté ici, repose sur ces caractéristiques et les intègre dans une hiérarchie structurelle ménageant un niveau informationnel correspondant aux traits (caractères), rassemblés dans un niveau de glyphes composés. La facilité d’utilisation de Typannot est assurée par le respect de quatre principes de conception (généricité, modularité, lisibilité et inscriptibilité) et l’utilisation d’une interface de saisie ménageant ces niveaux d’informations. Afin d’illustrer l’usage de Typannot, ont été menée des analyses portant sur les configurations et l’emplacement propre de la main, qui montrent l’influence de la gestualité praxique sur la gestualité symbolique (c.-à-d. les signes des LS). Vue la durée d’annotation encore très importante qu’un tel système de transcription impose, l’objectif est de permettre une "dictée gestuelle", une transcription directe à partir des données de capture de mouvement. Cette perspective devrait aussi faciliter la transcription de l’ensemble des gestes dits co-verbaux de n’importe quelle langue vocale.
    Keywords Social Sciences ; H
    Language English
    Publishing date 2020-01-01T00:00:00Z
    Publisher EDP Sciences
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Measurement of Prompt D^{0} Meson Azimuthal Anisotropy in Pb-Pb Collisions at sqrt[s_{NN}]=5.02  TeV.

    Sirunyan, A M / Tumasyan, A / Adam, W / Ambrogi, F / Asilar, E / Bergauer, T / Brandstetter, J / Brondolin, E / Dragicevic, M / Erö, J / Flechl, M / Friedl, M / Frühwirth, R / Ghete, V M / Grossmann, J / Hrubec, J / Jeitler, M / König, A / Krammer, N /
    Krätschmer, I / Liko, D / Madlener, T / Mikulec, I / Pree, E / Rabady, D / Rad, N / Rohringer, H / Schieck, J / Schöfbeck, R / Spanring, M / Spitzbart, D / Waltenberger, W / Wittmann, J / Wulz, C-E / Zarucki, M / Chekhovsky, V / Mossolov, V / Suarez Gonzalez, J / De Wolf, E A / Di Croce, D / Janssen, X / Lauwers, J / Van Haevermaet, H / Van Mechelen, P / Van Remortel, N / Abu Zeid, S / Blekman, F / D'Hondt, J / De Bruyn, I / De Clercq, J / Deroover, K / Flouris, G / Lontkovskyi, D / Lowette, S / Moortgat, S / Moreels, L / Python, Q / Skovpen, K / Tavernier, S / Van Doninck, W / Van Mulders, P / Van Parijs, I / Brun, H / Clerbaux, B / De Lentdecker, G / Delannoy, H / Fasanella, G / Favart, L / Goldouzian, R / Grebenyuk, A / Karapostoli, G / Lenzi, T / Luetic, J / Maerschalk, T / Marinov, A / Randle-Conde, A / Seva, T / Vander Velde, C / Vanlaer, P / Vannerom, D / Yonamine, R / Zenoni, F / Zhang, F / Cimmino, A / Cornelis, T / Dobur, D / Fagot, A / Gul, M / Khvastunov, I / Poyraz, D / Roskas, C / Salva, S / Tytgat, M / Verbeke, W / Zaganidis, N / Bakhshiansohi, H / Bondu, O / Brochet, S / Bruno, G / Caudron, A / De Visscher, S / Delaere, C / Delcourt, M / Francois, B / Giammanco, A / Jafari, A / Komm, M / Krintiras, G / Lemaitre, V / Magitteri, A / Mertens, A / Musich, M / Piotrzkowski, K / Quertenmont, L / Vidal Marono, M / Wertz, S / Beliy, N / Aldá Júnior, W L / Alves, F L / Alves, G A / Brito, L / Correa Martins Junior, M / Hensel, C / Moraes, A / Pol, M E / Rebello Teles, P / Belchior Batista Das Chagas, E / Carvalho, W / Chinellato, J / Custódio, A / Da Costa, E M / Da Silveira, G G / De Jesus Damiao, D / Fonseca De Souza, S / Huertas Guativa, L M / Malbouisson, H / Melo De Almeida, M / Mora Herrera, C / Mundim, L / Nogima, H / Santoro, A / Sznajder, A / Tonelli Manganote, E J / Torres Da Silva De Araujo, F / Vilela Pereira, A / Ahuja, S / Bernardes, C A / Fernandez Perez Tomei, T R / Gregores, E M / Mercadante, P G / Novaes, S F / Padula, Sandra S / Romero Abad, D / Ruiz Vargas, J C / Aleksandrov, A / Hadjiiska, R / Iaydjiev, P / Misheva, M / Rodozov, M / Shopova, M / Stoykova, S / Sultanov, G / Dimitrov, A / Glushkov, I / Litov, L / Pavlov, B / Petkov, P / Fang, W / Gao, X / Ahmad, M / Bian, J G / Chen, G M / Chen, H S / Chen, M / Chen, Y / Jiang, C H / Leggat, D / Liao, H / Liu, Z / Romeo, F / Shaheen, S M / Spiezia, A / Tao, J / Wang, C / Wang, Z / Yazgan, E / Zhang, H / Zhao, J / Ban, Y / Chen, G / Li, Q / Liu, S / Mao, Y / Qian, S J / Wang, D / Xu, Z / Avila, C / Cabrera, A / Chaparro Sierra, L F / Florez, C / González Hernández, C F / Ruiz Alvarez, J D / Courbon, B / Godinovic, N / Lelas, D / Puljak, I / Ribeiro Cipriano, P M / Sculac, T / Antunovic, Z / Kovac, M / Brigljevic, V / Ferencek, D / Kadija, K / Mesic, B / Starodumov, A / Susa, T / Ather, M W / Attikis, A / Mavromanolakis, G / Mousa, J / Nicolaou, C / Ptochos, F / Razis, P A / Rykaczewski, H / Finger, M / Carrera Jarrin, E / El-Khateeb, E / Elgammal, S / Ellithi Kamel, A / Dewanjee, R K / Kadastik, M / Perrini, L / Raidal, M / Tiko, A / Veelken, C / Eerola, P / Pekkanen, J / Voutilainen, M / Härkönen, J / Järvinen, T / Karimäki, V / Kinnunen, R / Lampén, T / Lassila-Perini, K / Lehti, S / Lindén, T / Luukka, P / Tuominen, E / Tuominiemi, J / Tuovinen, E / Talvitie, J / Tuuva, T / Besancon, M / Couderc, F / Dejardin, M / Denegri, D / Faure, J L / Ferri, F / Ganjour, S / Ghosh, S / Givernaud, A / Gras, P / Hamel de Monchenault, G / Jarry, P / Kucher, I / Locci, E / Machet, M / Malcles, J / Negro, G / Rander, J / Rosowsky, A / Sahin, M Ö / Titov, M / Abdulsalam, A / Antropov, I / Baffioni, S / Beaudette, F / Busson, P / Cadamuro, L / Charlot, C / Granier de Cassagnac, R / Jo, M / Lisniak, S / Lobanov, A / Martin Blanco, J / Nguyen, M / Ochando, C / Ortona, G / Paganini, P / Pigard, P / Regnard, S / Salerno, R / Sauvan, J B / Sirois, Y / Stahl Leiton, A G / Strebler, T / Yilmaz, Y / Zabi, A / Zghiche, A / Agram, J-L / Andrea, J / Bloch, D / Brom, J-M / Buttignol, M / Chabert, E C / Chanon, N / Collard, C / Conte, E / Coubez, X / Fontaine, J-C / Gelé, D / Goerlach, U / Jansová, M / Le Bihan, A-C / Tonon, N / Van Hove, P / Gadrat, S / Beauceron, S / Bernet, C / Boudoul, G / Chierici, R / Contardo, D / Depasse, P / El Mamouni, H / Fay, J / Finco, L / Gascon, S / Gouzevitch, M / Grenier, G / Ille, B / Lagarde, F / Laktineh, I B / Lethuillier, M / Mirabito, L / Pequegnot, A L / Perries, S / Popov, A / Sordini, V / Vander Donckt, M / Viret, S / Khvedelidze, A / Bagaturia, I / Autermann, C / Beranek, S / Feld, L / Kiesel, M K / Klein, K / Lipinski, M / Preuten, M / Schomakers, C / Schulz, J / Verlage, T / Albert, A / Dietz-Laursonn, E / Duchardt, D / Endres, M / Erdmann, M / Erdweg, S / Esch, T / Fischer, R / Güth, A / Hamer, M / Hebbeker, T / Heidemann, C / Hoepfner, K / Knutzen, S / Merschmeyer, M / Meyer, A / Millet, P / Mukherjee, S / Olschewski, M / Padeken, K / Pook, T / Radziej, M / Reithler, H / Rieger, M / Scheuch, F / Teyssier, D / Thüer, S / Flügge, G / Kargoll, B / Kress, T / Künsken, A / Lingemann, J / Müller, T / Nehrkorn, A / Nowack, A / Pistone, C / Pooth, O / Stahl, A / Aldaya Martin, M / Arndt, T / Asawatangtrakuldee, C / Beernaert, K / Behnke, O / Behrens, U / Bermúdez Martínez, A / Bin Anuar, A A / Borras, K / Botta, V / Campbell, A / Connor, P / Contreras-Campana, C / Costanza, F / Diez Pardos, C / Eckerlin, G / Eckstein, D / Eichhorn, T / Eren, E / Gallo, E / Garay Garcia, J / Geiser, A / Gizhko, A / Grados Luyando, J M / Grohsjean, A / Gunnellini, P / Harb, A / Hauk, J / Hempel, M / Jung, H / Kalogeropoulos, A / Kasemann, M / Keaveney, J / Kleinwort, C / Korol, I / Krücker, D / Lange, W / Lelek, A / Lenz, T / Leonard, J / Lipka, K / Lohmann, W / Mankel, R / Melzer-Pellmann, I-A / Meyer, A B / Mittag, G / Mnich, J / Mussgiller, A / Ntomari, E / Pitzl, D / Raspereza, A / Roland, B / Savitskyi, M / Saxena, P / Shevchenko, R / Spannagel, S / Stefaniuk, N / Van Onsem, G P / Walsh, R / Wen, Y / Wichmann, K / Wissing, C / Zenaiev, O / Bein, S / Blobel, V / Centis Vignali, M / Dreyer, T / Garutti, E / Gonzalez, D / Haller, J / Hinzmann, A / Hoffmann, M / Karavdina, A / Klanner, R / Kogler, R / Kovalchuk, N / Kurz, S / Lapsien, T / Marchesini, I / Marconi, D / Meyer, M / Niedziela, M / Nowatschin, D / Pantaleo, F / Peiffer, T / Perieanu, A / Scharf, C / Schleper, P / Schmidt, A / Schumann, S / Schwandt, J / Sonneveld, J / Stadie, H / Steinbrück, G / Stober, F M / Stöver, M / Tholen, H / Troendle, D / Usai, E / Vanelderen, L / Vanhoefer, A / Vormwald, B / Akbiyik, M / Barth, C / Baur, S / Butz, E / Caspart, R / Chwalek, T / Colombo, F / De Boer, W / Dierlamm, A / Freund, B / Friese, R / Giffels, M / Gilbert, A / Haitz, D / Hartmann, F / Heindl, S M / Husemann, U / Kassel, F / Kudella, S / Mildner, H / Mozer, M U / Müller, Th / Plagge, M / Quast, G / Rabbertz, K / Schröder, M / Shvetsov, I / Sieber, G / Simonis, H J / Ulrich, R / Wayand, S / Weber, M / Weiler, T / Williamson, S / Wöhrmann, 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Calvelli, V / Ferro, F / Robutti, E / Tosi, S / Brianza, L / Brivio, F / Ciriolo, V / Dinardo, M E / Fiorendi, S / Gennai, S / Ghezzi, A / Govoni, P / Malberti, M / Malvezzi, S / Manzoni, R A / Menasce, D / Moroni, L / Paganoni, M / Pauwels, K / Pedrini, D / Pigazzini, S / Ragazzi, S / Tabarelli de Fatis, T / Buontempo, S / Cavallo, N / Di Guida, S / Fabozzi, F / Fienga, F / Iorio, A O M / Khan, W A / Lista, L / Meola, S / Paolucci, P / Sciacca, C / Thyssen, F / Azzi, P / Bacchetta, N / Benato, L / Bisello, D / Boletti, A / Carlin, R / Carvalho Antunes De Oliveira, A / Checchia, P / De Castro Manzano, P / Dorigo, T / Dosselli, U / Gasparini, F / Gasparini, U / Gozzelino, A / Lacaprara, S / Margoni, M / Meneguzzo, A T / Pozzobon, N / Ronchese, P / Rossin, R / Simonetto, F / Torassa, E / Zanetti, M / Zotto, P / Zumerle, G / Braghieri, A / Fallavollita, F / Magnani, A / Montagna, P / Ratti, S P / Re, V / Ressegotti, M / Riccardi, C / Salvini, P / Vai, I / Vitulo, P / Alunni Solestizi, L / 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    Physical review letters

    2018  Volume 120, Issue 20, Page(s) 202301

    Abstract: The prompt D^{0} meson azimuthal anisotropy coefficients, v_{2} and v_{3}, are measured ... throughout the p_{T} range studied. The first measurement of the prompt D^{0} meson v_{3} coefficient is performed ... particles, a similar p_{T} dependence, but smaller magnitude for p_{T}<6  GeV/c, is found for prompt D^{0 ...

    Abstract The prompt D^{0} meson azimuthal anisotropy coefficients, v_{2} and v_{3}, are measured at midrapidity (|y|<1.0) in Pb-Pb collisions at a center-of-mass energy sqrt[s_{NN}]=5.02  TeV per nucleon pair with data collected by the CMS experiment. The measurement is performed in the transverse momentum (p_{T}) range of 1 to 40  GeV/c, for central and midcentral collisions. The v_{2} coefficient is found to be positive throughout the p_{T} range studied. The first measurement of the prompt D^{0} meson v_{3} coefficient is performed, and values up to 0.07 are observed for p_{T} around 4  GeV/c. Compared to measurements of charged particles, a similar p_{T} dependence, but smaller magnitude for p_{T}<6  GeV/c, is found for prompt D^{0} meson v_{2} and v_{3} coefficients. The results are consistent with the presence of collective motion of charm quarks at low p_{T} and a path length dependence of charm quark energy loss at high p_{T}, thereby providing new constraints on the theoretical description of the interactions between charm quarks and the quark-gluon plasma.
    Language English
    Publishing date 2018-05-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 208853-8
    ISSN 1079-7114 ; 0031-9007
    ISSN (online) 1079-7114
    ISSN 0031-9007
    DOI 10.1103/PhysRevLett.120.202301
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Studies of Beauty Suppression via Nonprompt D^{0} Mesons in Pb-Pb Collisions at sqrt[s_{NN}]=5.02  TeV.

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    Physical review letters

    2019  Volume 123, Issue 2, Page(s) 22001

    Abstract: The transverse momentum spectra of D^{0} mesons from b hadron decays are measured at midrapidity ... detector at the LHC. The D^{0} mesons from b hadron decays are distinguished from prompt D^{0} mesons ... D^{0} mesons and charged hadrons for p_{T} around 10  GeV/c. While theoretical calculations ...

    Abstract The transverse momentum spectra of D^{0} mesons from b hadron decays are measured at midrapidity (|y|<1) in pp and Pb-Pb collisions at a nucleon-nucleon center of mass energy of 5.02 TeV with the CMS detector at the LHC. The D^{0} mesons from b hadron decays are distinguished from prompt D^{0} mesons by their decay topologies. In Pb-Pb collisions, the B→D^{0} yield is found to be suppressed in the measured p_{T} range from 2 to 100  GeV/c as compared to pp collisions. The suppression is weaker than that of prompt D^{0} mesons and charged hadrons for p_{T} around 10  GeV/c. While theoretical calculations incorporating partonic energy loss in the quark-gluon plasma can successfully describe the measured B→D^{0} suppression at higher p_{T}, the data show an indication of larger suppression than the model predictions in the range of 2<p_{T}<5  GeV/c.<br />
    Language English
    Publishing date 2019-08-03
    Publishing country United States
    Document type Journal Article
    ZDB-ID 208853-8
    ISSN 1079-7114 ; 0031-9007
    ISSN (online) 1079-7114
    ISSN 0031-9007
    DOI 10.1103/PhysRevLett.123.022001
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  9. Article ; Online: Identification of highly potent and selective MMP2 inhibitors addressing the S1' subsite with d-proline-based compounds.

    Lenci, Elena / Innocenti, Riccardo / Di Francescantonio, Tommaso / Menchi, Gloria / Bianchini, Francesca / Contini, Alessandro / Trabocchi, Andrea

    Bioorganic & medicinal chemistry

    2019  Volume 27, Issue 9, Page(s) 1891–1902

    Abstract: ... subsite is the major driver to attain selective and potent inhibitors. The synthesis of d-proline-derived ...

    Abstract MMP2 and MMP9, also called gelatinases, play a primary role in the angiogenic switch, as a fundamental step of tumor progression, and show high degree of structural similarity. Clinically successful gelatinase inhibitors need to be highly selective as opposite effects have been found for the two enzymes, and the S1' subsite is the major driver to attain selective and potent inhibitors. The synthesis of d-proline-derived hydroxamic acids containing diverse appendages at the amino group, varying in length and decoration allowed to give insight on the MMP2/MMP9 selectivity around the S1' subsite, resulting in the identification of sub-nanomolar compounds with high selectivity up to 730. Molecular docking studies revealed the existence of an additional hydrophobic channel at the bottom of S1' subsite for MMP2 enzyme useful to drive selectivity towards such gelatinase.
    MeSH term(s) Amino Acid Sequence ; Binding Sites ; Cell Line, Tumor ; Cell Survival/drug effects ; Humans ; Hydroxamic Acids/chemical synthesis ; Hydroxamic Acids/chemistry ; Hydroxamic Acids/metabolism ; Matrix Metalloproteinase 2/chemistry ; Matrix Metalloproteinase 2/metabolism ; Matrix Metalloproteinase 9/chemistry ; Matrix Metalloproteinase 9/metabolism ; Matrix Metalloproteinase Inhibitors/chemistry ; Matrix Metalloproteinase Inhibitors/metabolism ; Matrix Metalloproteinase Inhibitors/pharmacology ; Molecular Docking Simulation ; Proline/chemistry ; Protein Structure, Tertiary ; Sequence Alignment ; Structure-Activity Relationship
    Chemical Substances Hydroxamic Acids ; Matrix Metalloproteinase Inhibitors ; Proline (9DLQ4CIU6V) ; Matrix Metalloproteinase 2 (EC 3.4.24.24) ; Matrix Metalloproteinase 9 (EC 3.4.24.35)
    Language English
    Publishing date 2019-03-22
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1161284-8
    ISSN 1464-3391 ; 0968-0896
    ISSN (online) 1464-3391
    ISSN 0968-0896
    DOI 10.1016/j.bmc.2019.03.043
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    Zs.A 3815: Show issues Location:
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  10. Article ; Online: D-Ring-Modified Analogues of Luotonin A with Reduced Planarity: Design, Synthesis, and Evaluation of Their Topoisomerase Inhibition-Associated Cytotoxicity.

    Almansour, Abdulrahman I / Kumar, Raju Suresh / Arumugam, Natarajan / Bianchini, Giulia / Menéndez, J Carlos / Mohammad, Faruq / Dupadahalli, Kotresha / Altaf, Mohammad

    BioMed research international

    2019  Volume 2019, Page(s) 2514524

    Abstract: A- and D-ring-modified luotonin-inspired heterocycles have been synthesized and were evaluated ...

    Abstract A- and D-ring-modified luotonin-inspired heterocycles have been synthesized and were evaluated for their activity against the viability of four cancer cell lines in vitro, namely, MCF7, HCT116, JURKAT, and NCI-H460. The analysis of results indicated that two of the synthesized derivatives displayed good inhibition against the growth of the human colon cancer HCT116 cell line, with potencies lower than but in the same order of magnitude as camptothecin (CPT). These two luotonin analogues also showed an activity similar to that of the highly potent alkaloid CPT as inhibitors of topoisomerase I and also inhibited topoisomerase II. These results show that complete planarity is not a strict requirement for topoisomerase inhibition by luotonin-related compounds, paving the way to the design of analogues with improved solubility.
    MeSH term(s) Alkaloids/pharmacology ; Antineoplastic Agents/pharmacology ; Camptothecin/analogs & derivatives ; Camptothecin/chemical synthesis ; Cell Line, Tumor/drug effects ; DNA Topoisomerases, Type I/drug effects ; DNA Topoisomerases, Type II/drug effects ; Enzyme Inhibitors/pharmacology ; Humans ; Molecular Docking Simulation ; Poly-ADP-Ribose Binding Proteins/drug effects ; Pyrroles/chemical synthesis ; Pyrroles/pharmacology ; Quinones/chemical synthesis ; Quinones/pharmacology ; Solubility ; Structure-Activity Relationship ; Topoisomerase Inhibitors/pharmacology
    Chemical Substances Alkaloids ; Antineoplastic Agents ; Enzyme Inhibitors ; Poly-ADP-Ribose Binding Proteins ; Pyrroles ; Quinones ; Topoisomerase Inhibitors ; luotonin A ; DNA Topoisomerases, Type I (EC 5.99.1.2) ; TOP1 protein, human (EC 5.99.1.2) ; DNA Topoisomerases, Type II (EC 5.99.1.3) ; TOP2A protein, human (EC 5.99.1.3) ; Camptothecin (XT3Z54Z28A)
    Language English
    Publishing date 2019-11-13
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2698540-8
    ISSN 2314-6141 ; 2314-6133
    ISSN (online) 2314-6141
    ISSN 2314-6133
    DOI 10.1155/2019/2514524
    Database MEDical Literature Analysis and Retrieval System OnLINE

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