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  1. Article ; Online: Advanced heart failure: parenteral diuretics for breathlessness and peripheral oedema - systematic review.

    Hughes, Alex / Oluyase, Adejoke O / Below, Natalie / Bajwah, Sabrina

    BMJ supportive & palliative care

    2024  Volume 14, Issue 1, Page(s) 1–13

    Abstract: Background: Advanced heart failure patients suffer with breathlessness and peripheral oedema, which are frequently treated with parenteral diuretics despite limited evidence.: Aim: To analyse the effectiveness of parenteral diuretics on ... ...

    Abstract Background: Advanced heart failure patients suffer with breathlessness and peripheral oedema, which are frequently treated with parenteral diuretics despite limited evidence.
    Aim: To analyse the effectiveness of parenteral diuretics on breathlessness and peripheral oedema in advanced heart failure patients.
    Methods: We searched Embase, MEDLINE(R), PsycINFO, CINAHL and CENTRAL from their respective inceptions to 2021, and performed handsearching, citation searching and grey literature search; limited to English publications. Selection criteria included parenteral (intravenous/subcutaneous) diuretic administration in advanced heart failure patients (New York Heart Association class III-IV). Two authors independently assessed articles for inclusion; one author extracted data. Data were synthesised through narrative synthesis or meta-analysed as appropriate.
    Results: 4646 records were screened; 6 trials (384 participants) were included. All were randomised controlled trials (RCTs) comparing intravenous continuous furosemide infusion (CFI) versus intravenous bolus furosemide infusion (BFI). Improvement in breathlessness and peripheral oedema (two studies, n=161, OR 2.80, 95% CI 1.45 to 5.40; I
    Conclusions: CFI appears to improve congestion in advanced heart failure patients in the short term. Available data came from small trials. Larger, prospective RCTs are recommended to address the evidence gap.
    MeSH term(s) Humans ; Diuretics/therapeutic use ; Furosemide/therapeutic use ; Heart Failure/complications ; Heart Failure/drug therapy ; Dyspnea/drug therapy ; Dyspnea/etiology ; Edema/drug therapy
    Chemical Substances Diuretics ; Furosemide (7LXU5N7ZO5)
    Language English
    Publishing date 2024-02-21
    Publishing country England
    Document type Journal Article
    ISSN 2045-4368
    ISSN (online) 2045-4368
    DOI 10.1136/spcare-2022-003863
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Comment on: "Advance" care planning reenvisioned.

    Bradshaw, Andy / Bayly, Joanne / Penfold, Clarissa / Lin, Cheng-Pei / Oluyase, Adejoke O / Hocaoglu, Mevhibe B / Murtagh, Fliss E M / Koffman, Jonathan

    Journal of the American Geriatrics Society

    2021  Volume 69, Issue 5, Page(s) 1177–1179

    MeSH term(s) Advance Care Planning ; Advance Directives ; Humans
    Language English
    Publishing date 2021-02-16
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 80363-7
    ISSN 1532-5415 ; 0002-8614
    ISSN (online) 1532-5415
    ISSN 0002-8614
    DOI 10.1111/jgs.17058
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Cardiovascular health promotion: A systematic review involving effectiveness of faith-based institutions in facilitating maintenance of normal blood pressure.

    Sanusi, Abayomi / Elsey, Helen / Golder, Su / Sanusi, Osayuwamen / Oluyase, Adejoke

    PLOS global public health

    2023  Volume 3, Issue 1, Page(s) e0001496

    Abstract: Globally, faith institutions have a range of beneficial social utility, but a lack of understanding remains regarding their role in cardiovascular health promotion, particularly for hypertension. Our objective was assessment of modalities, mechanisms and ...

    Abstract Globally, faith institutions have a range of beneficial social utility, but a lack of understanding remains regarding their role in cardiovascular health promotion, particularly for hypertension. Our objective was assessment of modalities, mechanisms and effectiveness of hypertension health promotion and education delivered through faith institutions. A result-based convergent mixed methods review was conducted with 24 databases including MEDLINE, Embase and grey literature sources searched on 30 March 2021, results independently screened by three researchers, and data extracted based on behaviour change theories. Quality assessment tools were selected by study design, from Cochrane risk of bias, ROBINS I and E, and The Joanna Briggs Institute's Qualitative Assessment and Review Instrument tools. Twenty-four publications contributed data. Faith institution roles include cardiovascular health/disease teaching with direct lifestyle linking, and teaching/ encouragement of personal psychological control. Also included were facilitation of: exercise/physical activity as part of normal lifestyle, nutrition change for cardiovascular health, cardiovascular health measurements, and opportunistic blood pressure checks. These demand relationships of trust with local leadership, contextualisation to local sociocultural realities, volitional participation but prior consent by faith / community leaders. Limited evidence for effectiveness: significant mean SBP reduction of 2.98 mmHg (95%CI -4.39 to -1.57), non-significant mean DBP increase of 0.14 mmHg (95%CI -2.74 to +3.01) three months after interventions; and significant mean SBP reduction of 0.65 mmHg (95%CI -0.91 to -0.39), non-significant mean DBP reduction of 0.53 mmHg (95%CI -1.86 to 0.80) twelve months after interventions. Body weight, waist circumference and multiple outcomes beneficially reduced for cardiovascular health: significant mean weight reduction 0.83kg (95% CI -1.19 to -0.46), and non-significant mean waist circumference reduction 1.48cm (95% CI -3.96 to +1.00). In addressing the global hypertension epidemic the cardiovascular health promotion roles of faith institutions probably hold unrealised potential. Deliberate cultural awareness, intervention contextualisation, immersive involvement of faith leaders and alignment with religious practice characterise their deployment as healthcare assets.
    Language English
    Publishing date 2023-01-20
    Publishing country United States
    Document type Journal Article
    ISSN 2767-3375
    ISSN (online) 2767-3375
    DOI 10.1371/journal.pgph.0001496
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: COVID-19 and palliative care capacity, African Region.

    Afolabi, Oladayo A / Abboah-Offei, Mary / Namisango, Eve / Chukwusa, Emeka / Oluyase, Adejoke O / Luyirika, Emmanuel Bk / Harding, Richard / Nkhoma, Kennedy

    Bulletin of the World Health Organization

    2021  Volume 99, Issue 8, Page(s) 542–542A

    MeSH term(s) COVID-19 ; Humans ; Palliative Care ; SARS-CoV-2 ; Surveys and Questionnaires
    Language English
    Publishing date 2021-08-05
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 80213-x
    ISSN 1564-0604 ; 0042-9686 ; 0366-4996 ; 0510-8659
    ISSN (online) 1564-0604
    ISSN 0042-9686 ; 0366-4996 ; 0510-8659
    DOI 10.2471/BLT.20.285286
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Correction: Charitably funded hospices and the challenges associated with the COVID-19 pandemic: a mixed-methods study (CovPall).

    Garner, Ian W / Walshe, Catherine / Dunleavy, Lesley / Bradshaw, Andy / Preston, Nancy / Fraser, Lorna K / Murtagh, Fliss Em / Oluyase, Adejoke O / Sleeman, Katherine E / Hocaoglu, Mevhibe / Bajwah, Sabrina / Chambers, Rachel L / Maddocks, Matthew / Higginson, Irene J

    BMC palliative care

    2022  Volume 21, Issue 1, Page(s) 190

    Language English
    Publishing date 2022-11-02
    Publishing country England
    Document type Published Erratum
    ZDB-ID 2091556-1
    ISSN 1472-684X ; 1472-684X
    ISSN (online) 1472-684X
    ISSN 1472-684X
    DOI 10.1186/s12904-022-01084-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Adaptation and multicentre validation of a patient-centred outcome scale for people severely ill with COVID (IPOS-COV).

    Hocaoglu, Mevhibe B / Murtagh, Fliss E M / Walshe, Catherine / Chambers, Rachel L / Maddocks, Matthew / Sleeman, Katherine E / Oluyase, Adejoke O / Dunleavy, Lesley / Bradshaw, Andy / Bajwah, Sabrina / Fraser, Lorna K / Preston, Nancy / Higginson, Irene J

    Health and quality of life outcomes

    2023  Volume 21, Issue 1, Page(s) 29

    Abstract: Background: Patient-centred measures to capture symptoms and concerns have rarely been reported in severe COVID. We adapted and tested the measurement properties of the proxy version of the Integrated Palliative care Outcome Scale-IPOS-COV for severe ... ...

    Abstract Background: Patient-centred measures to capture symptoms and concerns have rarely been reported in severe COVID. We adapted and tested the measurement properties of the proxy version of the Integrated Palliative care Outcome Scale-IPOS-COV for severe COVID using psychometric approach.
    Methods: We consulted experts and followed consensus-based standards for the selection of health status measurement instruments and United States Food and Drug Administration guidance for adaptation and analysis. Exploratory Factor Analysis and clinical perspective informed subscales. We tested the internal consistency reliability, calculated item total correlations, examined re-test reliability in stable patients, and also evaluated inter-rater reproducibility. We examined convergent and divergent validity of IPOS-COV with the Australia-modified Karnofsky Performance Scale and evaluated known-groups validity. Ability to detect change was examined.
    Results: In the adaptation phase, 6 new items were added, 7 items were removed from the original measure. The recall period was revised to be the last 12-24 h to capture fast deterioration in COVID. General format and response options of the original Integrated Palliative care Outcome Scale were preserved. Data from 572 patients with COVID from across England and Wales seen by palliative care services were included. Four subscales were supported by the 4-factor solution explaining 53.5% of total variance. Breathlessness-Agitation and Gastro-intestinal subscales demonstrated good reliability with high to moderate (a = 0.70 and a = 0.67) internal consistency, and item-total correlations (0.62-0.21). All except the Flu subscale discriminated well between patients with differing disease severity. Inter-rater reliability was fair with ICC of 0.40 (0.3-0.5, 95% CI, n = 324). Correlations between the subscales and AKPS as predicted were weak (r = 0.13-0.26) but significant (p < 0.01). Breathlessness-Agitation and Drowsiness-Delirium subscales demonstrated good divergent validity. Patients with low oxygen saturation had higher mean Breathlessness-Agitation scores (M = 5.3) than those with normal levels (M = 3.4), t = 6.4 (186), p < 0.001. Change in Drowsiness-Delirium subscale correctly classified patients who died.
    Conclusions: IPOS-COV is the first patient-centred measure adapted for severe COVID to support timely management. Future studies could further evaluate its responsiveness and clinical utility with clinimetric approaches.
    MeSH term(s) Humans ; Reproducibility of Results ; Quality of Life ; COVID-19 ; Palliative Care ; Psychometrics ; Delirium ; Surveys and Questionnaires
    Language English
    Publishing date 2023-03-24
    Publishing country England
    Document type Multicenter Study ; Journal Article
    ZDB-ID 2098765-1
    ISSN 1477-7525 ; 1477-7525
    ISSN (online) 1477-7525
    ISSN 1477-7525
    DOI 10.1186/s12955-023-02102-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Do the Clinical Management Guidelines for Covid-19 in African Countries Reflect the African Quality Palliative Care Standards? A Review of Current Guidelines.

    Afolabi, Oladayo A / Abboah-Offei, Mary / Namisango, Eve / Chukwusa, Emeka / Oluyase, Adejoke O / Luyirika, Emmanuel B K / Harding, Richard / Nkhoma, Kennedy

    Journal of pain and symptom management

    2021  Volume 61, Issue 5, Page(s) e17–e23

    Abstract: Context: Palliative care should be a component of COVID-19 management to relieve suffering, improve patient outcomes and save cost.: Objectives: We aimed to identify and critically appraise the palliative care recommendations within COVID-19 case ... ...

    Abstract Context: Palliative care should be a component of COVID-19 management to relieve suffering, improve patient outcomes and save cost.
    Objectives: We aimed to identify and critically appraise the palliative care recommendations within COVID-19 case management guidelines in African countries.
    Methods: The study employed systematic guideline review design. All guidelines from any country in Africa, of any language, published between December 2019 and June 2020 were retrieved through online search and email to in-country key contacts. We conducted a content analysis of the palliative care recommendations within the guidelines and appraised the recommendations using African Palliative Care Association standards for providing quality palliative care.
    Results: We retrieved documents from 29 of 54 African countries. Fifteen documents from 15 countries were included in the final analysis, of which eight countries have identifiable PC recommendations in their COVID-19 management guidelines. Of these eight, only one country (South Sudan) provided comprehensive palliative care recommendations covering the domains of physical, psychological, social and spiritual wellbeing, two (Namibia and Uganda) addressed only physical and psychological wellbeing while the remaining five countries addressed only physical symptom management.
    Conclusions: Comprehensive palliative care which addresses physical, psychological, social and spiritual concerns must be prioritized within case management guidelines in African countries.
    MeSH term(s) COVID-19 ; Humans ; Namibia ; Palliative Care ; SARS-CoV-2 ; Uganda
    Language English
    Publishing date 2021-02-19
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 639142-4
    ISSN 1873-6513 ; 0885-3924
    ISSN (online) 1873-6513
    ISSN 0885-3924
    DOI 10.1016/j.jpainsymman.2021.01.126
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Change in Activity of Palliative Care Services during the Covid-19 Pandemic: A Multinational Survey (CovPall).

    Sleeman, Katherine E / Cripps, Rachel L / Murtagh, Fliss E M / Oluyase, Adejoke O / Hocaoglu, Mevhibe B / Maddocks, Matthew / Walshe, Catherine / Preston, Nancy / Dunleavy, Lesley / Bradshaw, Andy / Bajwah, Sabrina / Higginson, Irene J / Fraser, Lorna K

    Journal of palliative medicine

    2021  Volume 25, Issue 3, Page(s) 465–471

    Abstract: Objectives: ...

    Abstract Objectives:
    MeSH term(s) COVID-19 ; Cross-Sectional Studies ; Humans ; Palliative Care ; Pandemics ; SARS-CoV-2
    Language English
    Publishing date 2021-12-20
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1427361-5
    ISSN 1557-7740 ; 1096-6218
    ISSN (online) 1557-7740
    ISSN 1096-6218
    DOI 10.1089/jpm.2021.0315
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Journal ; Article ; Online: COVID-19 and palliative care capacity, African Region

    Afolabi, Oladayo A / Abboah-Offei, Mary / Namisango, Eve / Chukwusa, Emeka / Oluyase, Adejoke O / Luyirika, Emmanuel BK / Harding, Richard / Nkhoma, Kennedy

    2021  

    Abstract: ... 542 ... ...

    Abstract 542

    542A
    Keywords Editorials
    Language English
    Publisher World Health Organization
    Document type Journal ; Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: Charitably funded hospices and the challenges associated with the COVID-19 pandemic: a mixed-methods study (CovPall).

    Garner, Ian W / Walshe, Catherine / Dunleavy, Lesley / Bradshaw, Andy / Preston, Nancy / Fraser, Lorna K / Murtagh, Fliss Em / Oluyase, Adejoke O / Sleeman, Katherine E / Hocaoglu, Mevhibe / Bajwah, Sabrina / Chambers, Rachel L / Maddocks, Matthew / Higginson, Irene J

    BMC palliative care

    2022  Volume 21, Issue 1, Page(s) 176

    Abstract: Background: Independent charitably funded hospices have been an important element of the UK healthcare response to the COVID-19 pandemic. Hospices usually have different funding streams, procurement processes, and governance arrangements compared to NHS ...

    Abstract Background: Independent charitably funded hospices have been an important element of the UK healthcare response to the COVID-19 pandemic. Hospices usually have different funding streams, procurement processes, and governance arrangements compared to NHS provision, which may affect their experiences during the COVID-19 pandemic. The aim of this study is to understand the challenges faced by charitably funded hospices during the COVID-19 pandemic.
    Methods: Eligible Organisations providing specialist palliative or hospice care completed the online CovPall survey (2020) which explored their response to the COVID-19 pandemic. Eligible organisations were then purposively selected to participate in interviews as part of qualitative case studies (2020-21) to understand challenges in more depth. Free-text responses from the survey were analysed using content analysis and were categorised accordingly. These categorisations were used a priori for a reflexive thematic analysis of interview data.
    Results: 143 UK independent charitably funded hospices completed the online CovPall survey. Five hospices subsequently participated in qualitative case studies (n = 24 staff interviews). Key themes include: vulnerabilities of funding; infection control during patient care; and bereavement support provision. Interviewees discussed the fragility of income due to fundraising events stopping; the difficulties of providing care to COVID-19 and non-COVID-19 patients within relatively small organisations; and challenges with maintaining the quality of bereavement services.
    Conclusion: Some unique care and provision challenges during the COVID-19 pandemic were highlighted by charitably funded hospices. Funding core services charitably and independently may affect their ability to respond to pandemics, or scenarios where resources are unexpectedly insufficient.
    MeSH term(s) COVID-19 ; Hospice Care ; Hospices ; Humans ; Palliative Care/methods ; Pandemics
    Language English
    Publishing date 2022-10-10
    Publishing country England
    Document type Journal Article
    ZDB-ID 2091556-1
    ISSN 1472-684X ; 1472-684X
    ISSN (online) 1472-684X
    ISSN 1472-684X
    DOI 10.1186/s12904-022-01070-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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