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  1. Article ; Online: The diversity of speech-perception difficulties among autistic individuals.

    Bendo, George J / Sturrock, Alexandra / Hanks, Graham / Plack, Christopher J / Gowen, Emma / Guest, Hannah

    Autism & developmental language impairments

    2024  Volume 9, Page(s) 23969415241227074

    Abstract: Background & aims: Communicative and sensory differences are core autistic traits, yet speech-perception abilities and difficulties among autistic individuals remain poorly understood. Laboratory studies have produced mixed and inconclusive results, in ... ...

    Abstract Background & aims: Communicative and sensory differences are core autistic traits, yet speech-perception abilities and difficulties among autistic individuals remain poorly understood. Laboratory studies have produced mixed and inconclusive results, in part because of the lack of input from autistic individuals in defining the hypotheses and shaping the methods used in this field of research. Little in-depth qualitative research on autistic experiences of speech perception has been published, yet such research could form the basis for better laboratory research, for improved understanding of autistic experiences, and for the development of interventions. Existing qualitative research describes widespread autistic listening differences with significant impacts, but these results rely on data gathered via oral interviews in a small sample. The present study addresses these limitations and employs a mixed-methods approach to explore autistic listening experiences.
    Methods: We gathered survey data from 79 autistic individuals aged 18-55 without diagnosed hearing loss. The questionnaire included 20 closed-set questions on listening abilities and difficulties and three free-text questions on listening experiences. The free-text questions underwent deductive content analysis using a framework composed of themes from previous interview data on listening experiences (including auditory differences, contributing factors, impacts, and coping strategies). Concepts in the free-text data that were not part of the analysis framework were analyzed inductively.
    Results: In the closed-set data, participants reported listening difficulties in most specified environments, but complex background sounds and particularly background voices caused the most difficulty. Those who reported listening difficulties expressed having substantially greater difficulties than other people the same age. Participants indicated multiple impacts from listening difficulties, most prominently in their social lives. Concepts in the free-text data strongly supported previous interview data on listening differences and factors that affect listening ability, especially the diversity of types of listening difficulties. Consistent with the closed-set data, background-sound complexity and concurrent voices were especially troubling. Some concepts in the free-text data were novel, particularly difficulties with remote, broadcast, and recorded audio, prompting the creation of new themes.
    Conclusions: Both forms of data indicate widespread listening differences-predominantly listening difficulties-affecting most autistic adults. Diverse types of listening difficulty are evident, potentially indicating heterogeneous underlying mechanisms, and complexity of background noise is consistently identified as an important factor. Listening difficulties are said to have substantial and varied impacts. Autistic adults are keen to share coping strategies, which are varied and usually self-devised.
    Implications: Based on both the quantitative and qualitative results, we provide recommendations to improve future research and support the autistic community. The data-revealing types of listening difficulties can guide better quantitative research into underlying mechanisms. Such research should take into account potential heterogeneity in listening difficulties. Suggestions for optimized collection of self-report data are also offered. Additionally, our results could be used to improve societal understanding of autistic listening differences and to create beneficial interventions for and with autistic individuals. Moreover, given the willingness of the autistic community to share coping strategies, systematic collation of these strategies could form the basis for self-help and clinical guidance.
    Language English
    Publishing date 2024-01-27
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2863109-2
    ISSN 2396-9415 ; 2396-9415
    ISSN (online) 2396-9415
    ISSN 2396-9415
    DOI 10.1177/23969415241227074
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Chasing the conversation: Autistic experiences of speech perception.

    Sturrock, Alexandra / Guest, Hannah / Hanks, Graham / Bendo, George / Plack, Christopher J / Gowen, Emma

    Autism & developmental language impairments

    2022  Volume 7, Page(s) 23969415221077532

    Abstract: Background and aims: Humans communicate primarily through spoken language and speech perception is a core function of the human auditory system. Among the autistic community, atypical sensory reactivity and social communication difficulties are ... ...

    Abstract Background and aims: Humans communicate primarily through spoken language and speech perception is a core function of the human auditory system. Among the autistic community, atypical sensory reactivity and social communication difficulties are pervasive, yet the research literature lacks in-depth self-report data on speech perception in this population. The present study aimed to elicit detailed first-person accounts of autistic individuals' abilities and difficulties perceiving the spoken word.
    Methods: Semi-structured interviews were conducted with nine autistic adults. The interview schedule addressed interviewees' experiences of speech perception, factors influencing those experiences, and responses to those experiences. Resulting interview transcripts underwent thematic analysis. The six-person study team included two autistic researchers, to reduce risk of neurotypical 'overshadowing' of autistic voices.
    Results: Most interviewees reported pronounced difficulties perceiving speech in the presence of competing sounds. They emphasised that such listening difficulties are distinct from social difficulties, though the two can add and interact. Difficulties were of several varieties, ranging from powerful auditory distraction to drowning out of voices by continuous sounds. Contributing factors encompassed not only features of the soundscape but also non-acoustic factors such as multisensory processing and social cognition. Participants also identified compounding factors, such as lack of understanding of listening difficulties. Impacts were diverse and sometimes disabling, affecting socialising, emotions, fatigue, career, and self-image. A wide array of coping mechanisms was described.
    Conclusions: The first in-depth qualitative investigation of autistic speech-perception experiences has revealed diverse and widespread listening difficulties. These can combine with other internal, interpersonal, and societal factors to induce profound impacts. Lack of understanding of such listening difficulties - by the self, by communication partners, by institutions, and especially by clinicians - appears to be a crucial exacerbating factor. Many autistic adults have developed coping strategies to lessen speech-perception difficulties or mitigate their effects, and these are generally self-taught due to lack of clinical support.
    Implications: There is a need for carefully designed, adequately powered confirmatory research to verify, quantify, and disentangle the various forms of listening difficulty, preferably using large samples to explore heterogeneity. More immediate benefit might be obtained through development of self-help and clinical guidance materials, and by raising awareness of autistic listening experiences and needs, among the autistic community, communication partners, institutions, and clinicians.
    Language English
    Publishing date 2022-02-24
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2863109-2
    ISSN 2396-9415 ; 2396-9415
    ISSN (online) 2396-9415
    ISSN 2396-9415
    DOI 10.1177/23969415221077532
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: The Impact of Tele-Education on Family Medicine Clerkship Students' Learning Outcomes.

    Unger, Kendra / Bors, Kathleen / Xiang, Jun / Lapp, Madison / Oreskovich, Jason / Higinbotham, Ashley / Snyder, Telista / Hanks, Heather / Ashcraft, Amie M

    Family medicine

    2023  Volume 55, Issue 9, Page(s) 616–619

    Abstract: Background and objectives: The COVID-19 pandemic necessitated rapid changes to medical education for student and patient protection. A dearth of published US studies examine resulting clinical education outcomes due to pandemic-induced curricula changes. ...

    Abstract Background and objectives: The COVID-19 pandemic necessitated rapid changes to medical education for student and patient protection. A dearth of published US studies examine resulting clinical education outcomes due to pandemic-induced curricula changes. We describe adaptations made to a family medicine clerkship to move it from traditional in-person delivery to virtual only, and then from virtual to hybrid; and compare educational outcomes of students across delivery types.
    Methods: We stratified 386 medical students in their third year completing their 8-week family medicine clerkship by type of content delivery, including in person, virtual only, and hybrid instruction. We examined the impact of these changes on three clerkship learning outcomes: the midblock assessment score, the National Board of Medical Examiners (NBME) exam score, and the final numeric score (FNS).
    Results: In our sample, 164 (42.5%) received content in person, 36 (9.3%) received virtual only, and 186 (48.2%) received hybrid content. Students receiving virtual only (M=76.4, SD=9.1) had significantly higher midblock assessment scores (F=8.06, df=2, P=.0004) than students receiving hybrid (M=71.7, SD=8.8) and in-person training (M=74.5, SD=7.2). No significant differences existed in students' NBME exam scores or FNSs across delivery types.
    Conclusions: Students receiving virtual-only or hybrid content performed at least as well on three clerkship-related educational outcomes as their pre-COVID peers participating in person. Further research is needed to understand how changes to medical education affected student learning and skill development.
    MeSH term(s) Humans ; Educational Measurement/methods ; Family Practice ; Pandemics ; Clinical Clerkship/methods ; Curriculum ; Students, Medical ; Clinical Competence
    Language English
    Publishing date 2023-07-24
    Publishing country United States
    Document type Journal Article
    ZDB-ID 639374-3
    ISSN 1938-3800 ; 0742-3225
    ISSN (online) 1938-3800
    ISSN 0742-3225
    DOI 10.22454/FamMed.2023.410835
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Radiation Exposure in Extracorporeal Life Support.

    Krishnan, Sudhir / Soltesz, Edward / Hanks, Justin / Adi, Ahmad / Elgharably, Haytham / McCurry, Kenneth / Bribriesco, Alejandro

    ASAIO journal (American Society for Artificial Internal Organs : 1992)

    2023  Volume 69, Issue 12, Page(s) 1049–1054

    Abstract: Extracorporeal membrane oxygenation (ECMO) exposes patients to multiple radiologic studies. We hypothesized ECMO patients endure radiation exposure in excess of the International Commission of Radiological Protection (ICRP) recommendations of cumulative ... ...

    Abstract Extracorporeal membrane oxygenation (ECMO) exposes patients to multiple radiologic studies. We hypothesized ECMO patients endure radiation exposure in excess of the International Commission of Radiological Protection (ICRP) recommendations of cumulative effective dose (CED, >20 mSv and 5-year cumulative limit of CED >100 mSv). We conducted a retrospective observational study in an academic medical center between January 2016 and December 2018 involving adult admissions (N = 306) on ECMO. Ionizing radiation was calculated from reference values to determine CED. Approximately 9.4% (N = 29) patients accrued CED >50 mSv and 4.5% (N = 14) accrued CED >100 mSv during ECMO. Over the entire hospitalization, 28% (N = 85) accrued >50 mSv and 14.7% (N = 45) accrued CED >100 mSv. Median CED during ECMO was 2.3 mSv (IQR, -0.82 to 8.1 mSv), and the entire hospitalization was 17.4 mSv (IQR, -4.5 to 56.6 mSv). Thirteen percent of the median CED accrued during hospitalization could be attributed to ECMO. Longer hospitalization was associated with a higher CED (50 days [IQR, -25 to 76 days] in CED >50 vs. 19 days [IQR, -10 to 32 days] in CED <50). Computer tomography (CT) scans and interventional radiology (IR) procedures contributed to 43.8% and 44.86%, respectively, of CED accrued on ECMO and 52.2% and 37.1% of CED accumulated during the whole hospitalization. Guidelines aimed at mitigating radiation exposure are urgently needed.
    MeSH term(s) Adult ; Humans ; Extracorporeal Membrane Oxygenation/adverse effects ; Tomography, X-Ray Computed ; Radiation Dosage ; Radiation Exposure/adverse effects ; Retrospective Studies
    Language English
    Publishing date 2023-10-24
    Publishing country United States
    Document type Observational Study ; Journal Article
    ZDB-ID 759982-1
    ISSN 1538-943X ; 0162-1432 ; 1058-2916
    ISSN (online) 1538-943X
    ISSN 0162-1432 ; 1058-2916
    DOI 10.1097/MAT.0000000000002037
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Critical care pharmacy service provision and workforce in adult extracorporeal membrane oxygenation centres: a multicentre cross-sectional survey.

    Remmington, Christopher / Cameron, Lynda / Hanks, Fraser / Liang, Ya-Hui / Barrow, Linda / Coxhead, Ruth / Mehta, Reena / Bhudia, Nisha / Lyster, Haifa / Cooke, Sarah / Gilmartin, James / Lee, Phillisa / Sloss, Rhona / McKenzie, Cathrine

    International journal of clinical pharmacy

    2024  

    Abstract: Background: There is good evidence describing pharmacy workforce and service provision in general critical care units. However, no data exist from adult extracorporeal membrane oxygenation (ECMO) centres.: Aim: To describe workforce characteristics, ... ...

    Abstract Background: There is good evidence describing pharmacy workforce and service provision in general critical care units. However, no data exist from adult extracorporeal membrane oxygenation (ECMO) centres.
    Aim: To describe workforce characteristics, pharmacy service provision, and pharmaceutical care activities in critical care units (CCUs) providing an adult ECMO service in the United Kingdom (UK) and compare to national staffing standards for CCUs.
    Method: We conducted a multicentre, cross-sectional electronic survey inviting one pharmacy professional response per UK ECMO centre. We collated information on workforce, service provision, and pharmaceutical care activities provided by pharmacy teams in adult CCUs with an ECMO service.
    Results: The survey response rate was 90.9%: representatives of 10/11 tertiary hospitals providing ECMO services responded. Median critical care pharmacist to critical care bed was 1:12.1 (IQR: 1:9.4-1:14.9). Most centres (90.0%) did not meet national standards for pharmacy professionals to critical care bed staffing ratios for weekday services. Total critical care beds covered by the critical care pharmacy team varied across the UK: median (IQR) - 45 (37-80) beds. Two centres funded pharmacist time for ECMO activity, and one centre funded a pharmacy technician post. Median peak ECMO activity was 4 ECMO patients in a single day (IQR: 3-5). Most respondents reported reduced pharmacy service at weekends compared to weekday, with limited on-site support.
    Conclusion: Most responding ECMO centres in the UK reported pharmacy staffing ratios below nationally agreed critical care standards. There was high variability in clinical pharmacy services to ECMO patients over 7 days.
    Language English
    Publishing date 2024-03-29
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2601204-2
    ISSN 2210-7711 ; 2210-7703 ; 0928-1231
    ISSN (online) 2210-7711
    ISSN 2210-7703 ; 0928-1231
    DOI 10.1007/s11096-024-01719-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: A cryogenically cooled 200 kV DC photoemission electron gun for ultralow emittance photocathodes.

    Gevorkyan, Gevork / Sarabia-Cardenas, Carlos / Kachwala, Alimohammad / Knill, Christopher / Hanks, Tatum J / Bhattacharyya, Priyadarshini / Li, William H / Cultrera, Luca / Galdi, Alice / Bazarov, Ivan / Maxson, Jared / Karkare, Siddharth

    The Review of scientific instruments

    2023  Volume 94, Issue 9

    Abstract: Novel photocathode materials like ordered surfaces of single crystal metals, epitaxially grown high quantum efficiency thin films, and topologically non-trivial materials with dirac cones show great promise for generating brighter electron beams for ... ...

    Abstract Novel photocathode materials like ordered surfaces of single crystal metals, epitaxially grown high quantum efficiency thin films, and topologically non-trivial materials with dirac cones show great promise for generating brighter electron beams for various accelerator and ultrafast electron scattering applications. Despite several materials being identified as brighter photocathodes, none of them have been tested in electron guns to extract electron beams due to technical and logistical challenges. In this paper, we present the design and commissioning of a cryocooled 200 kV DC electron gun that is capable of testing a wide variety of novel photocathode materials over a broad range of temperatures from 298 to 35 K for bright electron beam generation. This gun is designed to enable easy transfer of the photocathode to various standard ultra-high-vacuum surface diagnostics and preparation techniques, allowing a full characterization of the dependence of beam brightness on the photocathode material and surface properties. We demonstrate the development of such a high-voltage, high-gradient gun using materials and equipment that are easily available in any standard university lab, making the development of such 200 kV electron guns more accessible.
    Language English
    Publishing date 2023-09-14
    Publishing country United States
    Document type Journal Article
    ZDB-ID 209865-9
    ISSN 1089-7623 ; 0034-6748
    ISSN (online) 1089-7623
    ISSN 0034-6748
    DOI 10.1063/5.0160818
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: The longevity of chick tissue cultures without renewal of medium.

    HANKS, J H

    Journal of cellular and comparative physiology

    2008  Volume 31, Issue 2, Page(s) 235–260

    MeSH term(s) Animals ; Chickens ; Longevity ; Tissues/ethnology
    Language English
    Publishing date 2008-08-27
    Publishing country United States
    Document type Journal Article
    ZDB-ID 3117-3
    ISSN 0095-9898
    ISSN 0095-9898
    DOI 10.1002/jcp.1030310209
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Calcification of cell cultures in the presence of embryo juice and mamalian sera.

    HANKS, J H

    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.)

    2007  Volume 71, Issue 2, Page(s) 328–334

    MeSH term(s) Calcification, Physiologic ; Cell Culture Techniques ; Tissues/ethnology
    Language English
    Publishing date 2007-12-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 4015-0
    ISSN 1535-3699 ; 1525-1373 ; 0037-9727
    ISSN (online) 1535-3699 ; 1525-1373
    ISSN 0037-9727
    DOI 10.3181/00379727-71-17181
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Inorganic aging of the plasma layer of tissue cultures.

    HANKS, J H

    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.)

    2007  Volume 71, Issue 2, Page(s) 313–315

    MeSH term(s) Aging ; Immunologic Tests ; Plasma ; Research Design ; Tissues/ethnology
    Language English
    Publishing date 2007-12-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 4015-0
    ISSN 1535-3699 ; 1525-1373 ; 0037-9727
    ISSN (online) 1535-3699 ; 1525-1373
    ISSN 0037-9727
    DOI 10.3181/00379727-71-17175
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: A Comparison of Rural and Academic Training Environments for Third-Year Medical Students on a Family Medicine Rotation.

    Haggerty, Treah / Hanks, Heather / Xiang, Jun / Unger, Kendra / Dino, Geri

    Family medicine

    2019  Volume 51, Issue 5, Page(s) 430–433

    Abstract: Background and objectives: Medical students have been training in rural environments for many years. However, there is sparse research demonstrating that training in a rural environment provides an equivalent learning experience to training in an ... ...

    Abstract Background and objectives: Medical students have been training in rural environments for many years. However, there is sparse research demonstrating that training in a rural environment provides an equivalent learning experience to training in an academic medical setting. This study addresses that gap by comparing student performance after training in rural or community environment versus an academic setting while completing the family medicine clerkship.
    Methods: Participants in this retrospective cohort study were students who completed an 8-week family medicine third-year clerkship between 2013 and 2016. Half spent the first 4 weeks in a rural or community setting while the other half were in an academic setting. These placements were reversed after midterm exams. Data were collected from both student academic files and from rural rotation tracking systems at two time points: midterm and following the 8-week rotation.
    Results: Results from our sample of 159 medical students (89 [56.0%] male and 70 [44.0%] female) revealed no statistically significant differences in students' midterm (P=.63) and final scores (P=.74) based on training locations.
    Conclusions: Study findings suggest that rural and academic clerkships provide equivalent levels of knowledge for family medicine students. This finding has particular relevance for students whose intent is to practice in a rural location. Additional research is needed to identify if these findings are generalizable to other medical schools and locations.
    MeSH term(s) Clinical Clerkship ; Education, Medical, Undergraduate ; Educational Measurement/statistics & numerical data ; Family Practice ; Female ; Humans ; Male ; Professional Practice Location ; Retrospective Studies ; Rural Health Services ; Students, Medical
    Language English
    Publishing date 2019-05-13
    Publishing country United States
    Document type Comparative Study ; Journal Article
    ZDB-ID 639374-3
    ISSN 1938-3800 ; 0742-3225
    ISSN (online) 1938-3800
    ISSN 0742-3225
    DOI 10.22454/FamMed.2019.893411
    Database MEDical Literature Analysis and Retrieval System OnLINE

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