Article ; Online: METTL3 Gains R/W Access to the Epitranscriptome.
2016 Volume 62, Issue 3, Page(s) 323–324
Abstract: Epitranscriptomic marks are dynamically placed on mRNA by "writer" or "eraser" enzymes, while "readers" modulate their function accordingly. Lin et al. (2016) now report that the N6-methyladenosine:RNA methyltransferase METTL3 is both a writer and a ... ...
Abstract | Epitranscriptomic marks are dynamically placed on mRNA by "writer" or "eraser" enzymes, while "readers" modulate their function accordingly. Lin et al. (2016) now report that the N6-methyladenosine:RNA methyltransferase METTL3 is both a writer and a reader, directly enhancing mRNA translation. |
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MeSH term(s) | Methyltransferases/genetics ; RNA/genetics ; RNA, Messenger/genetics |
Chemical Substances | RNA, Messenger ; RNA (63231-63-0) ; Methyltransferases (EC 2.1.1.-) |
Language | English |
Publishing date | 2016-05-05 |
Publishing country | United States |
Document type | Journal Article |
ZDB-ID | 1415236-8 |
ISSN | 1097-4164 ; 1097-2765 |
ISSN (online) | 1097-4164 |
ISSN | 1097-2765 |
DOI | 10.1016/j.molcel.2016.04.024 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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